Succinate metabolism: A new therapeutic target for myocardial reperfusion injury

Cardiovascular Research

Volumn 111, Issue 2, 2016, Pages 134-141

  Pell, Victoria R ^a   Chouchani, Edward T ^b,c   Frezza, Christian ^d   Murphy, Michael P ^e   Krieg, Thomas ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Ischaemia Reperfusion; Mitochondria; Reactive oxygen species; Succinate

Indexed keywords

REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; CARDIOVASCULAR AGENT;

BIOACCUMULATION; CITRIC ACID CYCLE; DRUG TARGETING; ENZYME METABOLISM; HEART PROTECTION; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; ANIMAL; CARDIAC MUSCLE; DRUG EFFECTS; ELECTRON TRANSPORT; ENERGY METABOLISM; HUMAN; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CARDIOVASCULAR AGENTS; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; ENERGY METABOLISM; HUMANS; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUCCINIC ACID;

EID: 85007381729     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvw100     Document Type: Review

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