Hydroxytyrosol ameliorates insulin resistance by modulating endoplasmic reticulum stress and prevents hepatic steatosis in diet-induced obesity mice

Journal of Nutritional Biochemistry

Volumn 57, Issue , 2018, Pages 180-188

  Wang, Ningning ^a   Liu, Yang ^b   Ma, Yanan ^b   Wen, Deliang ^b  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Endoplasmic reticulum stress; Hydroxytyrosol; Insulin resistance; Liver steatosis; Obesity; Olive oil

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; FAS LIGAND; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYTYROSOL; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PALMITIC ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; VIRGIN OLIVE OIL; 3,4-DIHYDROXYPHENYLETHANOL; GLUCOSE; PHENETHYL ALCOHOL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CHRONIC INFLAMMATION; COMPARATIVE STUDY; CONTROLLED STUDY; DIET INDUCED OBESITY; ENDOPLASMIC RETICULUM STRESS; EPIDIDYMAL TISSUE; EXPERIMENTAL FATTY LIVER; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; HEP-G2 CELL LINE; HOMEOSTASIS MODEL ASSESSMENT; HUMAN; HUMAN CELL; IN VITRO STUDY; INGUINAL WHITE ADIPOSE TISSUE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN SIGNALING; INSULIN TOLERANCE TEST; LIPID DIET; LIPID STORAGE; LIPOGENESIS; LIVER PROTECTION; LIVER TISSUE; MALE; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; RETROPERITONEAL WHITE ADIPOSE TISSUE; SIGNAL TRANSDUCTION; TREATMENT DURATION; ADIPOSE TISSUE; ADVERSE EVENT; ANIMAL; COMPLICATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIPID METABOLISM; MAPK SIGNALING; METABOLISM; NONALCOHOLIC FATTY LIVER; OBESITY; PANNICULITIS; PHYSIOLOGY;

ADIPOSE TISSUE; ANIMALS; DIET, HIGH-FAT; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; GLUCOSE; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MAP KINASE SIGNALING SYSTEM; MICE, INBRED ICR; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY; PANNICULITIS; PHENYLETHYL ALCOHOL;

EID: 85046659662     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2018.03.018     Document Type: Article

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