Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice

Journal of Hepatology

Volumn 69, Issue 1, 2018, Pages 51-59

  Gong, Shenhai ^a   Lan, Tian ^d   Zeng, Liyan ^a   Luo, Haihua ^a   Yang, Xiaoyu ^a   Li, Na ^a   Chen, Xiaojiao ^a   Liu, Zhanguo ^e   Li, Rui ^d   Win, Sanda ^b   Liu, Shuwen ^a   Zhou, Hongwei ^a   Schnabl, Bernd ^c   Jiang, Yong ^a   Kaplowitz, Neil ^b   Chen, Peng ^a,e  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^e SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Acetaminophen; Acute liver injury; Gut microbiota; Metabolomics

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; LONG CHAIN FATTY ACID; PARACETAMOL; RNA 16S; SHORT CHAIN FATTY ACID; ANALGESIC AGENT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALISTIPES; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BACTERIAL LOAD; BACTEROIDES; CIRCADIAN RHYTHM; CONTROLLED STUDY; FECES MICROFLORA; FOOD INTAKE; IN VITRO STUDY; IN VIVO STUDY; INTESTINE FLORA; LACTOBACILLUS; LIVER CELL; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; MALE; METABOLOMICS; MICROBIOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TOXIC HEPATITIS; ANIMAL; BAGG ALBINO MOUSE; DISEASE MODEL; DRUG EFFECT; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; CHEMICAL AND DRUG INDUCED LIVER INJURY; CIRCADIAN RHYTHM; DISEASE MODELS, ANIMAL; GASTROINTESTINAL MICROBIOME; MALE; MICE; MICE, INBRED BALB C;

EID: 85045334125     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2018.02.024     Document Type: Article

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