Acetaminophen changes intestinal epithelial cell membrane properties, subsequently affecting absorption processes

Cellular Physiology and Biochemistry

Volumn 32, Issue 2, 2013, Pages 431-447

  Schäfer, Christine ^a   Schröder, Klaus Rudolf ^a   Höglinger, Otmar ^b   Tollabimazraehno, Sajjad ^c,d   Lornejad Schäfer, Mohammad Reza ^a  

^a BioMed Zet Life Science GmbH   (Austria)

^b UNIVERSITY OF APPLIED SCIENCES UPPER AUSTRIA   (Austria)

^c JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acetaminophen; Impedance; Intestinal barrier model; Membrane properties; Microvilli

Indexed keywords

ALKALINE PHOSPHATASE; DEXTRAN; MULTIDRUG RESISTANCE PROTEIN 1; PARACETAMOL; PROTEIN ZO1; FLUORESCEIN ISOTHIOCYANATE DEXTRAN;

ARTICLE; CAPACITANCE BLOOD VESSEL; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; CYTOTOXICITY; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; MEMBRANE PERMEABILITY; MICROVILLUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; ULTRASTRUCTURE ANALYSIS AND ELECTRON MICROSCOPY; WESTERN BLOTTING; APOPTOSIS; BASOLATERAL MEMBRANE; CACO 2 CELL LINE; CELL MEMBRANE PERMEABILITY; CELL ULTRASTRUCTURE; DOSE RESPONSE; DRUG CYTOTOXICITY; INTESTINE ABSORPTION; INTESTINE BRUSH BORDER; MITOCHONDRIAL MEMBRANE POTENTIAL; TRANSPORT ASSAY;

ABSORPTION; ACETAMINOPHEN; ALKALINE PHOSPHATASE; ANALGESICS, NON-NARCOTIC; CACO-2 CELLS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GPI-LINKED PROTEINS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MITOCHONDRIA;

EID: 84885579904     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000354449     Document Type: Article

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