Clock gene mPer2 functions in diurnal variation of acetaminophen induced hepatotoxicity in mice

Experimental and Toxicologic Pathology

Volumn 63, Issue 6, 2011, Pages 581-585

  Kakan, Xiamusiya ^a,b   Chen, Peng ^a   Zhang, Jianfa ^a  

^a NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b XINJIANG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Acetaminophen; Circadian; Cyp1a2; Mice; Period 2

Indexed keywords

CYTOCHROME P450 1A2; MESSENGER RNA; PARACETAMOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DISEASE SEVERITY; DRUG OVERDOSE; GENE; GENE EXPRESSION; LIVER TOXICITY; MALE; MOUSE; MPER2 GENE; NONHUMAN; WILD TYPE;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CIRCADIAN RHYTHM; CYTOCHROME P-450 ENZYME SYSTEM; DRUG-INDUCED LIVER INJURY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PERIOD CIRCADIAN PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION;

MAMMALIA; MUS;

EID: 79952707813     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2010.04.011     Document Type: Article

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