Single-Cell RNA-Seq Reveals Transcriptional Heterogeneity in Latent and Reactivated HIV-Infected Cells

Cell Reports

Volumn 23, Issue 4, 2018, Pages 942-950

  Golumbeanu, Monica ^a,b   Cristinelli, Sara ^c   Rato, Sylvie ^c   Munoz, Miguel ^c   Cavassini, Matthias ^c   Beerenwinkel, Niko ^a,b   Ciuffi, Angela ^c  

^a ETH ZURICH   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

cure; heterogeneity; HIV; inducible cell; latency; reactivation; scRNA seq; signature; single cell; transcriptome

Indexed keywords

T LYMPHOCYTE RECEPTOR; VORINOSTAT;

ARTICLE; CD4+ T LYMPHOCYTE; CELL HETEROGENEITY; CELL ISOLATION; CELL POPULATION; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; GENE CLUSTER; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IN VITRO STUDY; IN VIVO STUDY; LATENT VIRUS INFECTION; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RNA SEQUENCE; VIRUS CELL INTERACTION; VIRUS EXPRESSION; VIRUS LATENCY; VIRUS REACTIVATION; VIRUS TRANSCRIPTION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; METABOLISM; PHYSIOLOGY; SEQUENCE ANALYSIS; VIRUS ACTIVATION;

FEMALE; GENE EXPRESSION REGULATION, VIRAL; HIV INFECTIONS; HIV-1; HUMANS; MALE; SEQUENCE ANALYSIS, RNA; VIRUS ACTIVATION; VIRUS LATENCY;

EID: 85045284573     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2018.03.102     Document Type: Article

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