Pooling across cells to normalize single-cell RNA sequencing data with many zero counts

Genome Biology

Volumn 17, Issue 1, 2016, Pages

  Lun, Aaron T L ^a   Bach, Karsten ^b   Marioni, John C ^a,b,c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Differential expression; Normalization; Single cell RNA seq

Indexed keywords

BEHAVIOR; RNA SEQUENCE; ALGORITHM; ANIMAL; CALIBRATION; GENE EXPRESSION PROFILING; HUMAN; PROCEDURES; SEQUENCE ANALYSIS; SIGNAL NOISE RATIO; SINGLE CELL ANALYSIS; STANDARDS;

ALGORITHMS; ANIMALS; CALIBRATION; GENE EXPRESSION PROFILING; HUMANS; SEQUENCE ANALYSIS, RNA; SIGNAL-TO-NOISE RATIO; SINGLE-CELL ANALYSIS;

EID: 84964556059     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-0947-7     Document Type: Article

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