Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events

Cell Cycle

Volumn 13, Issue 9, 2014, Pages 1400-1412

  McCloy, Rachael A ^a   Rogers, Samuel ^a   Caldon, C Elizabeth ^a,b   Lorca, Thierry ^c   Castro, Anna ^c   Burgess, Andrew ^a,b  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b ST VINCENT'S CLINIC   (Australia)

^c UNIV MONTPELLIER   (France)

Author keywords

B1; Cdk1; Cyclin; Mitosis; PP2A; RO3306; SAC

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR; OKADAIC ACID; RO 3306; SECURIN; UNCLASSIFIED DRUG; QUINOLINE DERIVATIVE; THIAZOLE DERIVATIVE;

ARTICLE; CELL CYCLE G2 PHASE; CELL NUCLEUS MEMBRANE; CENTROSOME; CHROMOSOME ABERRATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINESIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; METAPHASE; MITOSIS; POLYPLOIDY; PROTEIN DEGRADATION; PROTEIN FUNCTION; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; HELA CELL LINE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SPINDLE APPARATUS; ULTRASTRUCTURE;

CDC2 PROTEIN KINASE; CENTROSOME; CYTOKINESIS; G2 PHASE; HELA CELLS; HUMANS; MITOSIS; OKADAIC ACID; PHOSPHORYLATION; POLYPLOIDY; QUINOLINES; SPINDLE APPARATUS; THIAZOLES;

EID: 84899714028     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.28401     Document Type: Article

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