-
1
-
-
84957940642
-
-
Fact Sheet 297
-
World Health Organization, “Cancer”, Fact Sheet No. 297, updated February 2017, http://www.who.int/mediacentre/factsheets/fs297/en/, (accessed February 21, 2017).
-
Cancer
-
-
-
3
-
-
77952310268
-
-
D. R. Fooksman, S. Vardhana, G. Vasiliver-Shamis, J. Liese, D. Blair, J. Waite, C. Sacristán, G. Victora, A. Zanin-Zhorov, M. L. Dustin, Annu. Rev. Immunol. 2010, 28, 79–105.
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 79-105
-
-
Fooksman, D.R.1
Vardhana, S.2
Vasiliver-Shamis, G.3
Liese, J.4
Blair, D.5
Waite, J.6
Sacristán, C.7
Victora, G.8
Zanin-Zhorov, A.9
Dustin, M.L.10
-
4
-
-
84925625990
-
-
1
-
A. M. Lesokhin, M. K. Callahan, M. A. Postow, J. D. Wolchok, Sci. Transl. Med. 2015, 7, 280sr1.
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 280sr
-
-
Lesokhin, A.M.1
Callahan, M.K.2
Postow, M.A.3
Wolchok, J.D.4
-
6
-
-
85006459521
-
-
M. Swart, I. Verbrugge, J. B. Beltman, Front. Oncol. 2016, 6, 233;
-
(2016)
Front. Oncol.
, vol.6
, pp. 233
-
-
Swart, M.1
Verbrugge, I.2
Beltman, J.B.3
-
7
-
-
85045238749
-
-
PD-1/PDL1 combination therapies, Evaluate Pharma May 2017
-
J. Plieth, E. Edhirst, PD-1/PDL1 combination therapies, Vantage, Evaluate Pharma May 2017.
-
-
-
Plieth, J.1
Edhirst, E.2
-
8
-
-
33748416499
-
-
G. Suntharalingam, M. R. Perry, S. Ward, S. J. Brett, A. Castello-Cortes, M. D. Brunner, N. Panoskaltsis, N. Engl. J. Med. 2006, 355, 1018–1028.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 1018-1028
-
-
Suntharalingam, G.1
Perry, M.R.2
Ward, S.3
Brett, S.J.4
Castello-Cortes, A.5
Brunner, M.D.6
Panoskaltsis, N.7
-
9
-
-
84940890382
-
-
J. L. Adams, J. Smothers, R. Srinivasan, A. Hoos, Nat. Rev. Drug Discovery 2015, 14, 603–622;
-
(2015)
Nat. Rev. Drug Discovery
, vol.14
, pp. 603-622
-
-
Adams, J.L.1
Smothers, J.2
Srinivasan, R.3
Hoos, A.4
-
12
-
-
85029624705
-
-
D. Dhanak, J. P. Edwards, A. Nguyen, P. J. Tummino, Cell Chem. Biol. 2017, 24, 1148–1160.
-
(2017)
Cell Chem. Biol.
, vol.24
, pp. 1148-1160
-
-
Dhanak, D.1
Edwards, J.P.2
Nguyen, A.3
Tummino, P.J.4
-
13
-
-
42949160646
-
-
D. Y.-w. Lin, Y. Tanaka, M. Iwasaki, A. G. Gittis, H.-P. Su, B. Mikami, T. Okazaki, T. Honjo, N. Minato, D. N. Garboczi, Proc. Natl. Acad. Sci. USA 2008, 105, 3011–3016.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3011-3016
-
-
Lin, D.Y.-W.1
Tanaka, Y.2
Iwasaki, M.3
Gittis, A.G.4
Su, H.-P.5
Mikami, B.6
Okazaki, T.7
Honjo, T.8
Minato, N.9
Garboczi, D.N.10
-
14
-
-
84949228878
-
-
K. M. Zak, R. Kitel, S. Przetocka, P. Golik, K. Guzik, B. Musielak, A. Dömling, G. Dubin, T. A. Holak, Structure 2015, 23, 2341–2348.
-
(2015)
Structure
, vol.23
, pp. 2341-2348
-
-
Zak, K.M.1
Kitel, R.2
Przetocka, S.3
Golik, P.4
Guzik, K.5
Musielak, B.6
Dömling, A.7
Dubin, G.8
Holak, T.A.9
-
15
-
-
85045234366
-
-
P. G. N. Sasikumar, M. Ramachandra, S. K. Vadlamani, K. R. Shrimali, K. Subbarao, WO2012/168944 A1, 2012;
-
(2012)
-
-
Sasikumar, P.G.N.1
Ramachandra, M.2
Vadlamani, S.K.3
Shrimali, K.R.4
Subbarao, K.5
-
18
-
-
85045241645
-
-
M. M. Miller, C. Mapelli, M. P. Allen, M. S. Bowsher, M. K. Boy, E. P. Gillis, D. R. Langley, E. Mull, M. A. Poirier, N. Sanghvi, L.-Q. Sun, D. J. Tenney, K.-S. Yeung, J. Zhu, P. C. Reid, P. M. Scola, WO2014/151634, 2014.
-
(2014)
-
-
Miller, M.M.1
Mapelli, C.2
Allen, M.P.3
Bowsher, M.S.4
Boy, M.K.5
Gillis, E.P.6
Langley, D.R.7
Mull, E.8
Poirier, M.A.9
Sanghvi, N.10
Sun, L.-Q.11
Tenney, D.J.12
Yeung, K.-S.13
Zhu, J.14
Reid, P.C.15
Scola, P.M.16
-
20
-
-
84971543833
-
-
K. M. Zak, P. Grudnik, K. Guzik, B. J. Zieba, B. Musielak, A. Dömling, G. Dubin, T. A. Holak, Oncotarget 2016, 7, 30323–30335.
-
(2016)
Oncotarget
, vol.7
, pp. 30323-30335
-
-
Zak, K.M.1
Grudnik, P.2
Guzik, K.3
Zieba, B.J.4
Musielak, B.5
Dömling, A.6
Dubin, G.7
Holak, T.A.8
-
22
-
-
85045273382
-
-
2017
-
J. J. Lee, J. D. Powderly, M. R. Patel, J. Brody, E. P. Hamilton, J. R. Infante, G. S. Falchook, H. W. Wang, L. Adams, L. Gong, A. W. Ma, T. Wyant, A. Lazorchak, S. Agarwal, D. P. Tuck, A. Daud, Poster Abstract Number: TPS3099 53rd Annual Meeting Am. Soc. Clin. Oncol. (ASCO), June 2–6, Chicago, 2017.
-
Clin. Oncol.
, pp. 2-6
-
-
Lee, J.J.1
Powderly, J.D.2
Patel, M.R.3
Brody, J.4
Hamilton, E.P.5
Infante, J.R.6
Falchook, G.S.7
Wang, H.W.8
Adams, L.9
Gong, L.10
Ma, A.W.11
Wyant, T.12
Lazorchak, A.13
Agarwal, S.14
Tuck, D.P.15
Daud, A.16
-
23
-
-
85045282213
-
-
https://clinicaltrials.gov NCT02812875, (accessed July 7, 2017).
-
-
-
-
24
-
-
85045246030
-
-
http://www.curis.com/images/stories/pdfs/posters/Aurigene_EORTC2016CA-327.pdf, (accessed July 7, 2017).
-
-
-
-
25
-
-
0037205048
-
-
L. C. Cantley, Science 2002, 296, 1655–1657.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
26
-
-
68249093818
-
-
P. Liu, H. Cheng, T. M. Roberts, J. J. Zhao, Nat. Rev. Drug Discovery 2009, 8, 627–644.
-
(2009)
Nat. Rev. Drug Discovery
, vol.8
, pp. 627-644
-
-
Liu, P.1
Cheng, H.2
Roberts, T.M.3
Zhao, J.J.4
-
27
-
-
84903188335
-
-
K. Ali, D. R. Soond, R. Pineiro, T. Hagemann, W. Pearce, E. L. Lim, H. Bouabe, C. L. Scudamore, T. Hancox, H. Maecker, L. Friedman, M. Turner, K. Okkenhaug, B. Vanhaesebroeck, Nature 2014, 510, 407–411.
-
(2014)
Nature
, vol.510
, pp. 407-411
-
-
Ali, K.1
Soond, D.R.2
Pineiro, R.3
Hagemann, T.4
Pearce, W.5
Lim, E.L.6
Bouabe, H.7
Scudamore, C.L.8
Hancox, T.9
Maecker, H.10
Friedman, L.11
Turner, M.12
Okkenhaug, K.13
Vanhaesebroeck, B.14
-
28
-
-
85045289634
-
-
https://clinicaltrials.gov, NCT02332980, (accessed July 28, 2017).
-
-
-
-
29
-
-
84907964717
-
-
S. Joshi, A. R. Singh, M. Zulcic, D. L. Durden, Mol. Cancer Res. 2014, 12, 1520–1531.
-
(2014)
Mol. Cancer Res.
, vol.12
, pp. 1520-1531
-
-
Joshi, S.1
Singh, A.R.2
Zulcic, M.3
Durden, D.L.4
-
30
-
-
79958696667
-
-
M. C. Schmid, C. J. Avraamides, H. C. Dippold, I. Franco, P. Foubert, L. G. Ellies, L. M. Acevedo, J. R. E. Manglicmot, X. Song, W. Wrasidlo, S. L. Blair, M. H. Ginsberg, D. A. Cheresh, E. Hirsch, S. J. Field, J. A. Varner, Cancer Cell 2011, 19, 715–727.
-
(2011)
Cancer Cell
, vol.19
, pp. 715-727
-
-
Schmid, M.C.1
Avraamides, C.J.2
Dippold, H.C.3
Franco, I.4
Foubert, P.5
Ellies, L.G.6
Acevedo, L.M.7
Manglicmot, J.R.E.8
Song, X.9
Wrasidlo, W.10
Blair, S.L.11
Ginsberg, M.H.12
Cheresh, D.A.13
Hirsch, E.14
Field, S.J.15
Varner, J.A.16
-
31
-
-
84986334019
-
-
C. A. Evans, T. Liu, A. Lescarbeau, S. J. Nair, L. Grenier, J. A. Pradeilles, Q. Glenadel, T. Tibbitts, A. M. Rowley, J. P. DiNitto, E. E. Brophy, E. L. O'Hearn, J. A. Ali, D. G. Winkler, S. I. Goldstein, P. O'Hearn, C. M. Martin, J. G. Hoyt, J. R. Soglia, C. Cheung, M. M. Pink, J. L. Proctor, V. J. Palombella, M. R. Tremblay, A. C. Castro, ACS Med. Chem. Lett. 2016, 7, 862–867.
-
(2016)
ACS Med. Chem. Lett.
, vol.7
, pp. 862-867
-
-
Evans, C.A.1
Liu, T.2
Lescarbeau, A.3
Nair, S.J.4
Grenier, L.5
Pradeilles, J.A.6
Glenadel, Q.7
Tibbitts, T.8
Rowley, A.M.9
DiNitto, J.P.10
Brophy, E.E.11
O'Hearn, E.L.12
Ali, J.A.13
Winkler, D.G.14
Goldstein, S.I.15
O'Hearn, P.16
Martin, C.M.17
Hoyt, J.G.18
Soglia, J.R.19
Cheung, C.20
Pink, M.M.21
Proctor, J.L.22
Palombella, V.J.23
Tremblay, M.R.24
Castro, A.C.25
more..
-
32
-
-
84996523368
-
-
M. M. Kaneda, K. S. Messer, N. Ralainirina, H. Li, C. J. Leem, S. Gorjestani, G. Woo, A. V. Nguyen, C. C. Figueiredo, P. Foubert, M. C. Schmid, M. Pink, D. G. Winkler, M. Rausch, V. J. Palombella, J. Kutok, K. McGovern, K. A. Frazer, X. Wu, M. Karin, R. Sasik, E. E. W. Cohen, J. A. Varner, Nature 2016, 539, 437–442.
-
(2016)
Nature
, vol.539
, pp. 437-442
-
-
Kaneda, M.M.1
Messer, K.S.2
Ralainirina, N.3
Li, H.4
Leem, C.J.5
Gorjestani, S.6
Woo, G.7
Nguyen, A.V.8
Figueiredo, C.C.9
Foubert, P.10
Schmid, M.C.11
Pink, M.12
Winkler, D.G.13
Rausch, M.14
Palombella, V.J.15
Kutok, J.16
McGovern, K.17
Frazer, K.A.18
Wu, X.19
Karin, M.20
Sasik, R.21
Cohen, E.E.W.22
Varner, J.A.23
more..
-
33
-
-
85045266913
-
-
https://clinicaltrials.gov, NCT02637531, (accessed July 28, 2017).
-
-
-
-
36
-
-
77953023274
-
-
L. Yang, Y. Pang, H. L. Moses, Trends Immunol. 2010, 31, 220–227.
-
(2010)
Trends Immunol.
, vol.31
, pp. 220-227
-
-
Yang, L.1
Pang, Y.2
Moses, H.L.3
-
37
-
-
85045268977
-
-
https://clinicaltrials.gov, (accessed July 28, 2017)
-
-
-
-
38
-
-
85045263758
-
-
NCT02423343;
-
NCT02423343;
-
-
-
-
39
-
-
85045275103
-
-
NCT02734160
-
NCT02734160.
-
-
-
-
40
-
-
84897055483
-
-
R. W. Hendriks, S. Yuvaraj, L. P. Kil, Nat. Rev. Cancer 2014, 14, 219–232.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 219-232
-
-
Hendriks, R.W.1
Yuvaraj, S.2
Kil, L.P.3
-
41
-
-
84888216911
-
-
J. A. Dubovsky, K. A. Beckwith, G. Natarajan, J. A. Woyach, S. Jaglowski, Y. Zhong, J. D. Hessler, T.-M. Liu, B. Y. Chang, K. M. Larkin, M. R. Stefanovski, D. L. Chappell, F. W. Frissora, L. L. Smith, K. A. Smucker, J. M. Flynn, J. A. Jones, L. A. Andritsos, K. Maddocks, A. M. Lehman, R. Furman, J. Sharman, A. Mishra, M. A. Caligiuri, A. R. Satoskar, J. J. Buggy, N. Muthusamy, A. J. Johnson, J. C. Byrd, Blood 2013, 122, 2539–2549.
-
(2013)
Blood
, vol.122
, pp. 2539-2549
-
-
Dubovsky, J.A.1
Beckwith, K.A.2
Natarajan, G.3
Woyach, J.A.4
Jaglowski, S.5
Zhong, Y.6
Hessler, J.D.7
Liu, T.-M.8
Chang, B.Y.9
Larkin, K.M.10
Stefanovski, M.R.11
Chappell, D.L.12
Frissora, F.W.13
Smith, L.L.14
Smucker, K.A.15
Flynn, J.M.16
Jones, J.A.17
Andritsos, L.A.18
Maddocks, K.19
Lehman, A.M.20
Furman, R.21
Sharman, J.22
Mishra, A.23
Caligiuri, M.A.24
Satoskar, A.R.25
Buggy, J.J.26
Muthusamy, N.27
Johnson, A.J.28
Byrd, J.C.29
more..
-
42
-
-
84924033378
-
-
E, –E
-
I. Sagiv-Barfi, H. E. K. Kohrt, D. K. Czerwinski, P. P. Ng, B. Y. Chang, R. Levy, Proc. Natl. Acad. Sci. USA 2015, 112, E966–E972.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 966-972
-
-
Sagiv-Barfi, I.1
Kohrt, H.E.K.2
Czerwinski, D.K.3
Ng, P.P.4
Chang, B.Y.5
Levy, R.6
-
43
-
-
85045285784
-
-
https://clinicaltrials.gov, (accessed July 28, 2017)
-
-
-
-
44
-
-
85045285916
-
-
NCT02899078;
-
NCT02899078;
-
-
-
-
45
-
-
85045244145
-
-
NCT02940301;
-
NCT02940301;
-
-
-
-
46
-
-
85045259199
-
-
NCT02420912;
-
NCT02420912;
-
-
-
-
47
-
-
85045250999
-
-
NCT02329847;
-
NCT02329847;
-
-
-
-
48
-
-
85045243695
-
-
NCT02733042
-
NCT02733042.
-
-
-
-
49
-
-
85045259783
-
-
https://clinicaltrials.gov, (accessed July 28, 2017)
-
-
-
-
50
-
-
85045247394
-
-
NCT02537444;
-
NCT02537444;
-
-
-
-
51
-
-
85045240766
-
-
NCT02362035;
-
NCT02362035;
-
-
-
-
52
-
-
85045269770
-
-
NCT02448303;
-
NCT02448303;
-
-
-
-
53
-
-
85045254256
-
-
NCT02362048;
-
NCT02362048;
-
-
-
-
54
-
-
85045235817
-
-
NCT02454179;
-
NCT02454179;
-
-
-
-
55
-
-
85045236839
-
-
NCT02351739
-
NCT02351739.
-
-
-
-
57
-
-
79961125367
-
-
I. M. E. Desar, J. F. M. Jacobs, C. A. Hulsbergen-vandeKaa, W. J. G. Oyen, P. F. A. Mulders, W. T. A. van der Graaf, G. J. Adema, C. M. L. van Herpen, I. J. M. de Vries, Int. J. Cancer 2011, 129, 507–512.
-
(2011)
Int. J. Cancer
, vol.129
, pp. 507-512
-
-
Desar, I.M.E.1
Jacobs, J.F.M.2
Hulsbergen-vandeKaa, C.A.3
Oyen, W.J.G.4
Mulders, P.F.A.5
van der Graaf, W.T.A.6
Adema, G.J.7
van Herpen, C.M.L.8
de Vries, I.J.M.9
-
58
-
-
84914176528
-
-
A. Amin, E. R. Plimack, J. R. Infante, M. S. Ernstoff, B. I. Rini, D. F. McDermott, J. J. Knox, S. K. Pal, M. H. Voss, P. Sharma, C. K. Kollmannsberger, D. Y. C. Heng, J. L. Spratlin, Y. Shen, J. F. Kurland, P. Gagnier, H. J. Hammers, J. Clin. Oncol. 2014, 32, 5010.
-
(2014)
J. Clin. Oncol.
, vol.32
, pp. 5010
-
-
Amin, A.1
Plimack, E.R.2
Infante, J.R.3
Ernstoff, M.S.4
Rini, B.I.5
McDermott, D.F.6
Knox, J.J.7
Pal, S.K.8
Voss, M.H.9
Sharma, P.10
Kollmannsberger, C.K.11
Heng, D.Y.C.12
Spratlin, J.L.13
Shen, Y.14
Kurland, J.F.15
Gagnier, P.16
Hammers, H.J.17
-
59
-
-
84976871907
-
-
H. Jiang, S. Hegde, B. L. Knolhoff, Y. Zhu, J. M. Herndon, M. A. Meyer, T. M. Nywening, W. G. Hawkins, I. M. Shapiro, D. T. Weaver, J. A. Pachter, A. Wang-Gillam, D. G. DeNardo, Nat. Med. 2016, 22, 851–860;
-
(2016)
Nat. Med.
, vol.22
, pp. 851-860
-
-
Jiang, H.1
Hegde, S.2
Knolhoff, B.L.3
Zhu, Y.4
Herndon, J.M.5
Meyer, M.A.6
Nywening, T.M.7
Hawkins, W.G.8
Shapiro, I.M.9
Weaver, D.T.10
Pachter, J.A.11
Wang-Gillam, A.12
DeNardo, D.G.13
-
60
-
-
85045260480
-
-
2017 (Chicago);
-
R. Bueno, R. R. Gill, P. H. Lizotte, Abstract Number: 8555, 53rd Annual Meeting Am. Soc. Clin. Oncol (ASCO), June 2–6 2017 (Chicago);
-
Oncol
, pp. 2-6
-
-
Bueno, R.1
Gill, R.R.2
Lizotte, P.H.3
-
61
-
-
85045271878
-
-
https://clinicaltrials.gov, NCT02758587, (accessed July 28, 2017);
-
-
-
-
62
-
-
85045259980
-
-
https://clinicaltrials.gov, NCT02943317, (accessed July 28, 2017).
-
-
-
-
63
-
-
85045250661
-
-
https://clinicaltrials.gov, NCT02546531, (accessed July 28, 2017).
-
-
-
-
65
-
-
84927666190
-
-
L. Liu, P. A. Mayes, S. Eastman, H. Shi, S. Yadavilli, T. Zhang, J. Yang, L. Seestaller-Wehr, S.-Y. Zhang, C. Hopson, L. Tsvetkov, J. Jing, S. Zhang, J. Smothers, A. Hoos, Clin. Cancer Res. 2015, 21, 1639–1651.
-
(2015)
Clin. Cancer Res.
, vol.21
, pp. 1639-1651
-
-
Liu, L.1
Mayes, P.A.2
Eastman, S.3
Shi, H.4
Yadavilli, S.5
Zhang, T.6
Yang, J.7
Seestaller-Wehr, L.8
Zhang, S.-Y.9
Hopson, C.10
Tsvetkov, L.11
Jing, J.12
Zhang, S.13
Smothers, J.14
Hoos, A.15
-
66
-
-
84995336454
-
-
J. C. Bendell, T. W. Kim, B. C. Goh, J. Wallin, D.-Y. Oh, S.-W. Han, C. B. Lee, M. D. Hellmann, J. Desai, J. H. Lewin, B. J. Solomon, L. Q. M. Chow, W. H. Miller, J. F. Gainor, K. Flaherty, J. R. Infante, M. Das-Thakur, P. Foster, E. Cha, Y.-J. Bang, J. Clin. Oncol. 2016, 34, 3502;
-
(2016)
J. Clin. Oncol.
, vol.34
, pp. 3502
-
-
Bendell, J.C.1
Kim, T.W.2
Goh, B.C.3
Wallin, J.4
Oh, D.-Y.5
Han, S.-W.6
Lee, C.B.7
Hellmann, M.D.8
Desai, J.9
Lewin, J.H.10
Solomon, B.J.11
Chow, L.Q.M.12
Miller, W.H.13
Gainor, J.F.14
Flaherty, K.15
Infante, J.R.16
Das-Thakur, M.17
Foster, P.18
Cha, E.19
Bang, Y.-J.20
more..
-
67
-
-
85045281523
-
-
NCT03108131;
-
https://clinicaltrials.gov, (accessed July 28, 2017), NCT03108131;
-
-
-
-
68
-
-
85045264216
-
-
NCT01656642;
-
NCT01656642;
-
-
-
-
69
-
-
85045266182
-
-
NCT02788279
-
NCT02788279.
-
-
-
-
70
-
-
84995616659
-
-
B. Alford, K. Cox, H. Soliman, Drugs Future 2016, 41, 553.
-
(2016)
Drugs Future
, vol.41
, pp. 553
-
-
Alford, B.1
Cox, K.2
Soliman, H.3
-
72
-
-
85045262750
-
-
Bristol-Myers Squibb To Expand Its Immuno-Oncology Pipeline with Agreement to Acquire Flexus Biosciences, Inc
-
Bristol-Myers Squibb To Expand Its Immuno-Oncology Pipeline with Agreement to Acquire Flexus Biosciences, Inc., Press Release Bristol-Myers Squibb, Feb 23, 2015, (accessed June 8, 2017).
-
(2015)
-
-
-
73
-
-
85045287035
-
-
https://clinicaltrials.gov, (accessed July 28, 2017)
-
-
-
-
74
-
-
85045259235
-
-
NCT03196232;
-
NCT03196232;
-
-
-
-
75
-
-
85045281542
-
-
NCT02752074;
-
NCT02752074;
-
-
-
-
76
-
-
85045268299
-
-
NCT02178722;
-
NCT02178722;
-
-
-
-
77
-
-
85045288838
-
-
NCT02862457;
-
NCT02862457;
-
-
-
-
78
-
-
85045288461
-
-
NCT03085914
-
NCT03085914.
-
-
-
-
79
-
-
84978175044
-
-
C. Jochems, M. Fantini, R. I. Fernando, A. R. Kwilas, R. N. Donahue, L. M. Lepone, I. Grenga, Y.-S. Kim, M. W. Brechbiel, J. L. Gulley, R. A. Madan, C. R. Heery, J. W. Hodge, R. Newton, J. Schlom, K. Y. Tsang, Oncotarget 2016, 7, 37762–37772.
-
(2016)
Oncotarget
, vol.7
, pp. 37762-37772
-
-
Jochems, C.1
Fantini, M.2
Fernando, R.I.3
Kwilas, A.R.4
Donahue, R.N.5
Lepone, L.M.6
Grenga, I.7
Kim, Y.-S.8
Brechbiel, M.W.9
Gulley, J.L.10
Madan, R.A.11
Heery, C.R.12
Hodge, J.W.13
Newton, R.14
Schlom, J.15
Tsang, K.Y.16
-
80
-
-
85045236009
-
-
Search in
-
Search in: https://clinicaltrials.gov using the search term “Epacadostat”, (accessed July 17, 2017).
-
-
-
-
82
-
-
84880688294
-
-
R. Metz, S. Rust, J. B. DuHadaway, M. R. Mautino, D. H. Munn, N. N. Vahanian, C. J. Link, G. C. Prendergast, Oncoimmunology 2012, 1, 1460–1468.
-
(2012)
Oncoimmunology
, vol.1
, pp. 1460-1468
-
-
Metz, R.1
Rust, S.2
DuHadaway, J.B.3
Mautino, M.R.4
Munn, D.H.5
Vahanian, N.N.6
Link, C.J.7
Prendergast, G.C.8
-
84
-
-
85045268241
-
-
https://clinicaltrials.gov, NCT02764151, (accessed July 28, 2017).
-
-
-
-
85
-
-
50949115838
-
-
S. Ryzhov, S. V. Novitskiy, D. P. Carbone, I. Biaggioni, R. Zaynagetdinov, A. E. Goldstein, M. M. Dikov, I. Feoktistov, Neoplasia 2008, 10, 987–995.
-
(2008)
Neoplasia
, vol.10
, pp. 987-995
-
-
Ryzhov, S.1
Novitskiy, S.V.2
Carbone, D.P.3
Biaggioni, I.4
Zaynagetdinov, R.5
Goldstein, A.E.6
Dikov, M.M.7
Feoktistov, I.8
-
86
-
-
84930587811
-
-
D. Preti, P. G. Baraldi, A. R. Moorman, P. A. Borea, K. Varani, Med. Res. Rev. 2015, 35, 790–848.
-
(2015)
Med. Res. Rev.
, vol.35
, pp. 790-848
-
-
Preti, D.1
Baraldi, P.G.2
Moorman, A.R.3
Borea, P.A.4
Varani, K.5
-
88
-
-
59449094359
-
-
R. J. Gillespie, S. J. Bamford, R. Botting, M. Comer, S. Denny, S. Gaur, M. Griffin, A. M. Jordan, A. R. Knight, J. Lerpiniere, S. Leonardi, S. Lightowler, S. McAteer, A. Merrett, A. Misra, A. Padfield, M. Reece, M. Saadi, D. L. Selwood, G. C. Stratton, D. Surry, R. Todd, X. Tong, V. Ruston, R. Upton, S. M. Weiss, J. Med. Chem. 2009, 52, 33–47.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 33-47
-
-
Gillespie, R.J.1
Bamford, S.J.2
Botting, R.3
Comer, M.4
Denny, S.5
Gaur, S.6
Griffin, M.7
Jordan, A.M.8
Knight, A.R.9
Lerpiniere, J.10
Leonardi, S.11
Lightowler, S.12
McAteer, S.13
Merrett, A.14
Misra, A.15
Padfield, A.16
Reece, M.17
Saadi, M.18
Selwood, D.L.19
Stratton, G.C.20
Surry, D.21
Todd, R.22
Tong, X.23
Ruston, V.24
Upton, R.25
Weiss, S.M.26
more..
-
89
-
-
85045288834
-
-
https://clinicaltrials.gov, NCT03099161, (accessed July 19, 2017).
-
-
-
-
90
-
-
85045243874
-
-
Abstract 5598;
-
P. Ho, M.-Y. Hsieh, A. Hotson, R. Miller, I. McCaffery, S. Willingham, Proceedings of the American Association of Cancer Research (AACR), Annual Meeting 2017, Washington, April, 1–5, Abstract No. 5598;
-
-
-
Ho, P.1
Hsieh, M.-Y.2
Hotson, A.3
Miller, R.4
McCaffery, I.5
Willingham, S.6
-
91
-
-
85045259434
-
-
https://clinicaltrials.gov, NCT02655822, (accessed March 17, 2017).
-
-
-
-
92
-
-
85045232839
-
-
https://clinicaltrials.gov, NCT02403193, (accessed March 17, 2017).
-
-
-
-
93
-
-
85045280984
-
-
https://clinicaltrials.gov, NCT02740985, (accessed March 17, 2017).
-
-
-
-
94
-
-
85045290449
-
-
A. Borodovsky, Y. Wang, M. YeK. F. Sachsenmeier, H. Deng, K. J. Delsignore, A. J. FretlandR. J. Goodwin, N. Strittmatter, C. Hay, V. R. Sah, D. Lawson, C. Reimer, M. Congreve, J. S. Mason, H. Marshall, P. Lyne, R. Woessner, J. C. Shaw, J. D. Clarke, Proceedings of the American Association of Cancer Research (AACR), Annual Meeting 2017, Washington, April, 1–5, Abstract No. 5580.
-
Shaw
, pp. 1-5
-
-
Borodovsky, A.1
Wang, Y.2
Ye, M.3
Sachsenmeier, K.F.4
Deng, H.5
Delsignore, K.J.6
Fretland, A.J.7
Goodwin, R.J.8
Strittmatter, N.9
Hay, C.10
Sah, V.R.11
Lawson, D.12
Reimer, C.13
Congreve, M.14
Mason, J.S.15
Marshall, H.16
Lyne, P.17
Woessner, R.18
-
99
-
-
84976515614
-
-
C. W. Steele, S. A. Karim, J. D. G. Leach, P. Bailey, R. Upstill-Goddard, L. Rishi, M. Foth, S. Bryson, K. McDaid, Z. Wilson, C. Eberlein, J. B. Candido, M. Clarke, C. Nixon, J. Connelly, N. Jamieson, C. R. Carter, F. Balkwill, D. K. Chang, T. R. J. Evans, D. Strathdee, A. V. Biankin, R. J. B. Nibbs, S. T. Barry, O. J. Sansom, J. P. Morton, Cancer Cell 2016, 29, 832–845.
-
(2016)
Cancer Cell
, vol.29
, pp. 832-845
-
-
Steele, C.W.1
Karim, S.A.2
Leach, J.D.G.3
Bailey, P.4
Upstill-Goddard, R.5
Rishi, L.6
Foth, M.7
Bryson, S.8
McDaid, K.9
Wilson, Z.10
Eberlein, C.11
Candido, J.B.12
Clarke, M.13
Nixon, C.14
Connelly, J.15
Jamieson, N.16
Carter, C.R.17
Balkwill, F.18
Chang, D.K.19
Evans, T.R.J.20
Strathdee, D.21
Biankin, A.V.22
Nibbs, R.J.B.23
Barry, S.T.24
Sansom, O.J.25
Morton, J.P.26
more..
-
100
-
-
84887512876
-
-
H. Katoh, D. Wang, T. Daikoku, H. Sun, S. K. Dey, R. N. DuBois, Cancer Cell 2013, 24, 631–644.
-
(2013)
Cancer Cell
, vol.24
, pp. 631-644
-
-
Katoh, H.1
Wang, D.2
Daikoku, T.3
Sun, H.4
Dey, S.K.5
DuBois, R.N.6
-
101
-
-
84929940191
-
-
D. J. Nicholls, K. Wiley, I. Dainty, F. MacIntosh, C. Phillips, A. Gaw, C. K. Mårdh, J. Pharmacol. Exp. Ther. 2015, 353, 340.
-
(2015)
J. Pharmacol. Exp. Ther.
, vol.353
, pp. 340
-
-
Nicholls, D.J.1
Wiley, K.2
Dainty, I.3
MacIntosh, F.4
Phillips, C.5
Gaw, A.6
Mårdh, C.K.7
-
104
-
-
85018869328
-
-
X. Lu, J. W. Horner, E. Paul, X. Shang, P. Troncoso, P. Deng, S. Jiang, Q. Chang, D. J. Spring, P. Sharma, J. A. Zebala, D. Y. Maeda, Y. A. Wang, R. A. DePinho, Nature 2017, 543, 728–732.
-
(2017)
Nature
, vol.543
, pp. 728-732
-
-
Lu, X.1
Horner, J.W.2
Paul, E.3
Shang, X.4
Troncoso, P.5
Deng, P.6
Jiang, S.7
Chang, Q.8
Spring, D.J.9
Sharma, P.10
Zebala, J.A.11
Maeda, D.Y.12
Wang, Y.A.13
DePinho, R.A.14
-
105
-
-
85045290423
-
-
https://clinicaltrials.gov, NCT03161431, (accessed July3, 2017).
-
-
-
-
106
-
-
84860390598
-
-
R
-
M. Yan, N. Jene, D. Byrne, E. K. A. Millar, S. A. O'Toole, C. M. McNeil, G. J. Bates, A. L. Harris, A. H. Banham, R. L. Sutherland, S. B. Fox, Breast Cancer Res. 2011, 13, R47.
-
(2011)
Breast Cancer Res.
, vol.13
, pp. 47
-
-
Yan, M.1
Jene, N.2
Byrne, D.3
Millar, E.K.A.4
O'Toole, S.A.5
McNeil, C.M.6
Bates, G.J.7
Harris, A.L.8
Banham, A.H.9
Sutherland, R.L.10
Fox, S.B.11
-
107
-
-
84883198880
-
-
B. Debnath, S. Xu, F. Grande, A. Garofalo, N. Neamati, Theranostics 2013, 3, 47–75.
-
(2013)
Theranostics
, vol.3
, pp. 47-75
-
-
Debnath, B.1
Xu, S.2
Grande, F.3
Garofalo, A.4
Neamati, N.5
-
108
-
-
84991022228
-
-
L. Reinholdt, M. B. Laursen, A. Schmitz, J. S. Bødker, L. H. Jakobsen, M. Bøgsted, H. E. Johnsen, K. Dybkær, Biomarker Research 2016, 4, 12;
-
(2016)
Biomarker Research
, vol.4
, pp. 12
-
-
Reinholdt, L.1
Laursen, M.B.2
Schmitz, A.3
Bødker, J.S.4
Jakobsen, L.H.5
Bøgsted, M.6
Johnsen, H.E.7
Dybkær, K.8
-
109
-
-
85045242525
-
-
https://clinicaltrials.gov NCT00694590, (accessed July 5, 2017).
-
-
-
-
110
-
-
85045269084
-
-
https://clinicaltrials.gov NCT02923531, (accessed July 5, 2017).
-
-
-
-
111
-
-
85045231995
-
-
https://clinicaltrials.gov NCT02823405, (accessed July 5, 2017).
-
-
-
-
112
-
-
84923369983
-
-
S.-B. Peng, X. Zhang, D. Paul, L. M. Kays, W. Gough, J. Stewart, M. T. Uhlik, Q. Chen, Y.-H. Hui, M. J. Zamek-Gliszczynski, J. A. Wijsman, K. M. Credille, L. Z. Yan, Mol. Cancer Ther. 2015, 14, 480–490;
-
(2015)
Mol. Cancer Ther.
, vol.14
, pp. 480-490
-
-
Peng, S.-B.1
Zhang, X.2
Paul, D.3
Kays, L.M.4
Gough, W.5
Stewart, J.6
Uhlik, M.T.7
Chen, Q.8
Hui, Y.-H.9
Zamek-Gliszczynski, M.J.10
Wijsman, J.A.11
Credille, K.M.12
Yan, L.Z.13
-
113
-
-
85045255731
-
-
https://clinicaltrials.gov NCT02737072, (accessed July 6, 2017).
-
-
-
-
114
-
-
85045255281
-
-
https://clinicaltrials.gov, (accessed July 6, 2017)
-
-
-
-
115
-
-
85045262358
-
-
NCT02907099;
-
NCT02907099;
-
-
-
-
116
-
-
85045281281
-
-
NCT02826486
-
NCT02826486.
-
-
-
-
117
-
-
85045249712
-
-
https://clinicaltrials.gov, NCT03154827, (accessed July 6, 2017).
-
-
-
-
118
-
-
83455258270
-
-
C.-B. Xue, A. Wang, Q. Han, Y. Zhang, G. Cao, H. Feng, T. Huang, C. Zheng, M. Xia, K. Zhang, L. Kong, J. Glenn, R. Anand, D. Meloni, D. J. Robinson, L. Shao, L. Storace, M. Li, R. O. Hughes, R. Devraj, P. A. Morton, D. J. Rogier, M. Covington, P. Scherle, S. Diamond, T. Emm, S. Yeleswaram, N. Contel, K. Vaddi, R. Newton, G. Hollis, B. Metcalf, ACS Med. Chem. Lett. 2011, 2, 913–918.
-
(2011)
ACS Med. Chem. Lett.
, vol.2
, pp. 913-918
-
-
Xue, C.-B.1
Wang, A.2
Han, Q.3
Zhang, Y.4
Cao, G.5
Feng, H.6
Huang, T.7
Zheng, C.8
Xia, M.9
Zhang, K.10
Kong, L.11
Glenn, J.12
Anand, R.13
Meloni, D.14
Robinson, D.J.15
Shao, L.16
Storace, L.17
Li, M.18
Hughes, R.O.19
Devraj, R.20
Morton, P.A.21
Rogier, D.J.22
Covington, M.23
Scherle, P.24
Diamond, S.25
Emm, T.26
Yeleswaram, S.27
Contel, N.28
Vaddi, K.29
Newton, R.30
Hollis, G.31
Metcalf, B.32
more..
-
119
-
-
84962367349
-
-
T. M. Nywening, A. Wang-Gillam, D. E. Sanford, B. A. Belt, R. Z. Panni, B. M. Cusworth, A. T. Toriola, R. K. Nieman, L. A. Worley, M. Yano, K. J. Fowler, A. C. Lockhart, R. Suresh, B. R. Tan, K.-H. Lim, R. C. Fields, S. M. Strasberg, W. G. Hawkins, D. G. DeNardo, S. P. Goedegebuure, D. C. Linehan, Lancet Oncol. 2016, 17, 651–662.
-
(2016)
Lancet Oncol.
, vol.17
, pp. 651-662
-
-
Nywening, T.M.1
Wang-Gillam, A.2
Sanford, D.E.3
Belt, B.A.4
Panni, R.Z.5
Cusworth, B.M.6
Toriola, A.T.7
Nieman, R.K.8
Worley, L.A.9
Yano, M.10
Fowler, K.J.11
Lockhart, A.C.12
Suresh, R.13
Tan, B.R.14
Lim, K.-H.15
Fields, R.C.16
Strasberg, S.M.17
Hawkins, W.G.18
DeNardo, D.G.19
Goedegebuure, S.P.20
Linehan, D.C.21
more..
-
120
-
-
85045251628
-
-
https://clinicaltrials.gov, NCT01413022, (accessed July 5, 2017).
-
-
-
-
121
-
-
85045267066
-
-
https://clinicaltrials.gov, NCT02732938, (accessed July 5, 2017).
-
-
-
-
122
-
-
85045241164
-
-
http://ir.chemocentryx.com/releasedetail.cfm?releaseid=987568, (accessed July 4, 2017);
-
-
-
-
123
-
-
85045257048
-
-
https://clinicaltrials.gov, NCT02345408, (accessed July 5, 2017).
-
-
-
-
124
-
-
85045241799
-
-
http://ir.chemocentryx.com/releasedetail.cfm?releaseid=998139, (accessed July 7, 2017).
-
-
-
-
125
-
-
84962698261
-
-
N. Halama, I. Zoernig, A. Berthel, C. Kahlert, F. Klupp, M. Suarez-Carmona, T. Suetterlin, K. Brand, J. Krauss, F. Lasitschka, T. Lerchl, C. Luckner-Minden, A. Ulrich, M. Koch, J. Weitz, M. Schneider, M. W. Buechler, L. Zitvogel, T. Herrmann, A. Benner, C. Kunz, S. Luecke, C. Springfeld, N. Grabe, C. S. Falk, D. Jaeger, Cancer Cell 2016, 29, 587–601.
-
(2016)
Cancer Cell
, vol.29
, pp. 587-601
-
-
Halama, N.1
Zoernig, I.2
Berthel, A.3
Kahlert, C.4
Klupp, F.5
Suarez-Carmona, M.6
Suetterlin, T.7
Brand, K.8
Krauss, J.9
Lasitschka, F.10
Lerchl, T.11
Luckner-Minden, C.12
Ulrich, A.13
Koch, M.14
Weitz, J.15
Schneider, M.16
Buechler, M.W.17
Zitvogel, L.18
Herrmann, T.19
Benner, A.20
Kunz, C.21
Luecke, S.22
Springfeld, C.23
Grabe, N.24
Falk, C.S.25
Jaeger, D.26
more..
-
126
-
-
85045288722
-
-
https://clinicaltrials.gov, NCT01736813, (accessed July 4, 2017).
-
-
-
-
129
-
-
85045239649
-
-
https://www.clinicaltrials.gov, NCT03184870, (accessed July 3, 2017).
-
-
-
-
132
-
-
84971294694
-
-
M. Terranova-Barberio, S. Thomas, P. N. Munster, Immunotherapy 2016, 8, 705–719.
-
(2016)
Immunotherapy
, vol.8
, pp. 705-719
-
-
Terranova-Barberio, M.1
Thomas, S.2
Munster, P.N.3
-
133
-
-
84905994658
-
-
K. Kim, A. D. Skora, Z. Li, Q. Liu, A. J. Tam, R. L. Blosser, L. A. Diaz, N. Papadopoulos, K. W. Kinzler, B. Vogelstein, S. Zhou, Proc. Natl. Acad. Sci. USA 2014, 111, 11774–11779.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 11774-11779
-
-
Kim, K.1
Skora, A.D.2
Li, Z.3
Liu, Q.4
Tam, A.J.5
Blosser, R.L.6
Diaz, L.A.7
Papadopoulos, N.8
Kinzler, K.W.9
Vogelstein, B.10
Zhou, S.11
-
134
-
-
85012992223
-
-
K. Li, S. Qu, X. Chen, Q. Wu, M. Shi, Int. J. Mol. Sci. 2017, 18, 404.
-
(2017)
Int. J. Mol. Sci.
, vol.18
, pp. 404
-
-
Li, K.1
Qu, S.2
Chen, X.3
Wu, Q.4
Shi, M.5
-
135
-
-
0012929728
-
-
K. Takeda, T. Kaisho, S. Akira, Annu. Rev. Immunol. 2003, 21, 335–376.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, S.3
-
137
-
-
84878414390
-
-
S. Kaczanowska, A. M. Joseph, E. Davila, J. Leukocyte Biol. 2013, 93, 847–863;
-
(2013)
J. Leukocyte Biol.
, vol.93
, pp. 847-863
-
-
Kaczanowska, S.1
Joseph, A.M.2
Davila, E.3
-
139
-
-
77950542752
-
-
E. J. Hennessy, A. E. Parker, L. A. J. O'Neill, Nat. Rev. Drug Discovery 2010, 9, 293–307.
-
(2010)
Nat. Rev. Drug Discovery
, vol.9
, pp. 293-307
-
-
Hennessy, E.J.1
Parker, A.E.2
O'Neill, L.A.J.3
-
140
-
-
84900850520
-
-
R. J. Mancini, L. Stutts, K. A. Ryu, J. K. Tom, A. P. Esser-Kahn, ACS Chem. Biol. 2014, 9, 1075–1085.
-
(2014)
ACS Chem. Biol.
, vol.9
, pp. 1075-1085
-
-
Mancini, R.J.1
Stutts, L.2
Ryu, K.A.3
Tom, J.K.4
Esser-Kahn, A.P.5
-
141
-
-
84903884741
-
-
J. P. Pradere, D. H. Dapito, R. F. Schwabe, Oncogene 2014, 33, 3485–3495.
-
(2014)
Oncogene
, vol.33
, pp. 3485-3495
-
-
Pradere, J.P.1
Dapito, D.H.2
Schwabe, R.F.3
-
143
-
-
2342473348
-
-
J. Geisse, I. Caro, J. Lindholm, L. Golitz, P. Stampone, M. Owens, J. Am. Acad. Dermatol. 2004, 50, 722–733;
-
(2004)
J. Am. Acad. Dermatol.
, vol.50
, pp. 722-733
-
-
Geisse, J.1
Caro, I.2
Lindholm, J.3
Golitz, L.4
Stampone, P.5
Owens, M.6
-
144
-
-
84870999117
-
-
T. Meyer, C. Surber, L. E. French, E. Stockfleth, Expert Opin. Invest. Drugs 2013, 22, 149–159;
-
(2013)
Expert Opin. Invest. Drugs
, vol.22
, pp. 149-159
-
-
Meyer, T.1
Surber, C.2
French, L.E.3
Stockfleth, E.4
-
145
-
-
84875878203
-
-
A. Walter, M. Schäfer, V. Cecconi, C. Matter, M. Urosevic-Maiwald, B. Belloni, N. Schönewolf, R. Dummer, W. Bloch, S. Werner, H.-D. Beer, A. Knuth, M. van den Broek, Nat. Commun. 2013, 4, 1560.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1560
-
-
Walter, A.1
Schäfer, M.2
Cecconi, V.3
Matter, C.4
Urosevic-Maiwald, M.5
Belloni, B.6
Schönewolf, N.7
Dummer, R.8
Bloch, W.9
Werner, S.10
Beer, H.-D.11
Knuth, A.12
van den Broek, M.13
-
146
-
-
85045283036
-
-
e31–, e37
-
N. M. Donin, K. Chamie, A. T. Lenis, A. J. Pantuck, M. Reddy, D. Kivlin, J. Holldack, R. Pozzi, G. Hakim, L. I. Karsh, D. L. Lamm, L. H. Belkoff, A. S. Belldegrun, S. Holden, N. Shore, Urol. Oncol. Semin. Orig. Invest. 2017, 35, 39.e31–39.e37.
-
(2017)
Urol. Oncol. Semin. Orig. Invest.
, vol.35
, pp. 39
-
-
Donin, N.M.1
Chamie, K.2
Lenis, A.T.3
Pantuck, A.J.4
Reddy, M.5
Kivlin, D.6
Holldack, J.7
Pozzi, R.8
Hakim, G.9
Karsh, L.I.10
Lamm, D.L.11
Belkoff, L.H.12
Belldegrun, A.S.13
Holden, S.14
Shore, N.15
-
147
-
-
84942938920
-
-
A. H. Rook, J. M. Gelfand, M. Wysocka, A. B. Troxel, B. Benoit, C. Surber, R. Elenitsas, M. A. Buchanan, D. S. Leahy, R. Watanabe, I. R. Kirsch, E. J. Kim, R. A. Clark, Blood 2015, 126, 1452.
-
(2015)
Blood
, vol.126
, pp. 1452
-
-
Rook, A.H.1
Gelfand, J.M.2
Wysocka, M.3
Troxel, A.B.4
Benoit, B.5
Surber, C.6
Elenitsas, R.7
Buchanan, M.A.8
Leahy, D.S.9
Watanabe, R.10
Kirsch, I.R.11
Kim, E.J.12
Clark, R.A.13
-
148
-
-
37249041922
-
-
A. Z. Dudek, C. Yunis, L. I. Harrison, S. Kumar, R. Hawkinson, S. Cooley, J. P. Vasilakos, K. S. Gorski, J. S. Miller, Clin. Cancer Res. 2007, 13, 7119–7125.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 7119-7125
-
-
Dudek, A.Z.1
Yunis, C.2
Harrison, L.I.3
Kumar, S.4
Hawkinson, R.5
Cooley, S.6
Vasilakos, J.P.7
Gorski, K.S.8
Miller, J.S.9
-
149
-
-
84904387563
-
-
D. W. Northfelt, R. K. Ramanathan, P. A. Cohen, D. D. Von Hoff, G. J. Weiss, G. N. Dietsch, K. L. Manjarrez, T. D. Randall, R. M. Hershberg, Clin. Cancer Res. 2014, 20, 3683–3691.
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 3683-3691
-
-
Northfelt, D.W.1
Ramanathan, R.K.2
Cohen, P.A.3
Von Hoff, D.D.4
Weiss, G.J.5
Dietsch, G.N.6
Manjarrez, K.L.7
Randall, T.D.8
Hershberg, R.M.9
-
150
-
-
85045237773
-
-
https://clinicaltrials.gov NCT02556463, (accessed July 6, 2017).
-
-
-
-
151
-
-
84859812538
-
-
D. H. Dapito, A. Mencin, G.-Y. Gwak, J.-P. Pradere, M.-K. Jang, I. Mederacke, J. M. Caviglia, H. Khiabanian, A. Adeyemi, R. Bataller, J. H. Lefkowitch, M. Bower, R. Friedman, R. B. Sartor, R. Rabadan, R. F. Schwabe, Cancer Cell 2012, 21, 504–516;
-
(2012)
Cancer Cell
, vol.21
, pp. 504-516
-
-
Dapito, D.H.1
Mencin, A.2
Gwak, G.-Y.3
Pradere, J.-P.4
Jang, M.-K.5
Mederacke, I.6
Caviglia, J.M.7
Khiabanian, H.8
Adeyemi, A.9
Bataller, R.10
Lefkowitch, J.H.11
Bower, M.12
Friedman, R.13
Sartor, R.B.14
Rabadan, R.15
Schwabe, R.F.16
-
152
-
-
36549082403
-
-
M. Fukata, A. Chen, A. S. Vamadevan, J. Cohen, K. Breglio, S. Krishnareddy, R. Xu, N. Harpaz, A. J. Dannenberg, K. Subbaramaiah, H. S. Cooper, S. H. Itzkowitz, M. T. Abreu, Gastroenterology 2007, 133, 1869–1881;
-
(2007)
Gastroenterology
, vol.133
, pp. 1869-1881
-
-
Fukata, M.1
Chen, A.2
Vamadevan, A.S.3
Cohen, J.4
Breglio, K.5
Krishnareddy, S.6
Xu, R.7
Harpaz, N.8
Dannenberg, A.J.9
Subbaramaiah, K.10
Cooper, H.S.11
Itzkowitz, S.H.12
Abreu, M.T.13
-
153
-
-
84867605321
-
-
H. Tye, C. L. Kennedy, M. Najdovska, L. McLeod, W. McCormack, N. Hughes, A. Dev, W. Sievert, C. H. Ooi, T.-o. Ishikawa, H. Oshima, P. S. Bhathal, A. E. Parker, M. Oshima, P. Tan, B. J. Jenkins, Cancer Cell 2012, 22, 466–478;
-
(2012)
Cancer Cell
, vol.22
, pp. 466-478
-
-
Tye, H.1
Kennedy, C.L.2
Najdovska, M.3
McLeod, L.4
McCormack, W.5
Hughes, N.6
Dev, A.7
Sievert, W.8
Ooi, C.H.9
Ishikawa, T.-O.10
Oshima, H.11
Bhathal, P.S.12
Parker, A.E.13
Oshima, M.14
Tan, P.15
Jenkins, B.J.16
-
154
-
-
84868627145
-
-
A. Ochi, C. S. Graffeo, C. P. Zambirinis, A. Rehman, M. Hackman, N. Fallon, R. M. Barilla, J. R. Henning, M. Jamal, R. Rao, S. Greco, M. Deutsch, M. V. Medina-Zea, U. B. Saeed, M. O. Ego-Osuala, C. Hajdu, G. Miller, J. Clin. Invest. 2012, 122, 4118–4129;
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4118-4129
-
-
Ochi, A.1
Graffeo, C.S.2
Zambirinis, C.P.3
Rehman, A.4
Hackman, M.5
Fallon, N.6
Barilla, R.M.7
Henning, J.R.8
Jamal, M.9
Rao, R.10
Greco, S.11
Deutsch, M.12
Medina-Zea, M.V.13
Saeed, U.B.14
Ego-Osuala, M.O.15
Hajdu, C.16
Miller, G.17
-
156
-
-
33748271299
-
-
M. Fukata, A. Chen, A. Klepper, S. Krishnareddy, A. S. Vamadevan, L. S. Thomas, R. Xu, H. Inoue, M. Arditi, A. J. Dannenberg, M. T. Abreu, Gastroenterology 2006, 131, 862–877;
-
(2006)
Gastroenterology
, vol.131
, pp. 862-877
-
-
Fukata, M.1
Chen, A.2
Klepper, A.3
Krishnareddy, S.4
Vamadevan, A.S.5
Thomas, L.S.6
Xu, R.7
Inoue, H.8
Arditi, M.9
Dannenberg, A.J.10
Abreu, M.T.11
-
157
-
-
77951196379
-
-
J. Cherfils-Vicini, S. Platonova, M. Gillard, L. Laurans, P. Validire, R. Caliandro, P. Magdeleinat, F. Mami-Chouaib, M.-C. Dieu-Nosjean, W.-H. Fridman, D. Damotte, C. Sautès-Fridman, I. Cremer, J. Clin. Invest. 2010, 120, 1285–1297.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1285-1297
-
-
Cherfils-Vicini, J.1
Platonova, S.2
Gillard, M.3
Laurans, L.4
Validire, P.5
Caliandro, R.6
Magdeleinat, P.7
Mami-Chouaib, F.8
Dieu-Nosjean, M.-C.9
Fridman, W.-H.10
Damotte, D.11
Sautès-Fridman, C.12
Cremer, I.13
-
158
-
-
70350664389
-
-
Y. Sato, Y. Goto, N. Narita, D. S. B. Hoon, Cancer Microenviron. 2009, 2, 205–214.
-
(2009)
Cancer Microenviron.
, vol.2
, pp. 205-214
-
-
Sato, Y.1
Goto, Y.2
Narita, N.3
Hoon, D.S.B.4
-
160
-
-
84941805904
-
-
Q. Wang, X. Liu, Q. Zhou, C. Wang, Expert Opin. Ther. Targets 2015, 19, 1397–1409.
-
(2015)
Expert Opin. Ther. Targets
, vol.19
, pp. 1397-1409
-
-
Wang, Q.1
Liu, X.2
Zhou, Q.3
Wang, C.4
-
161
-
-
84928199174
-
-
252
-
J. Fu, D. B. Kanne, M. Leong, L. H. Glickman, S. M. McWhirter, E. Lemmens, K. Mechette, J. J. Leong, P. Lauer, W. Liu, K. E. Sivick, Q. Zeng, K. C. Soares, L. Zheng, D. A. Portnoy, J. J. Woodward, D. M. Pardoll, T. W. Dubensky, Y. Kim, Sci. Transl. Med. 2015, 7, 283ra252.
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 283ra
-
-
Fu, J.1
Kanne, D.B.2
Leong, M.3
Glickman, L.H.4
McWhirter, S.M.5
Lemmens, E.6
Mechette, K.7
Leong, J.J.8
Lauer, P.9
Liu, W.10
Sivick, K.E.11
Zeng, Q.12
Soares, K.C.13
Zheng, L.14
Portnoy, D.A.15
Woodward, J.J.16
Pardoll, D.M.17
Dubensky, T.W.18
Kim, Y.19
-
162
-
-
84903383252
-
-
T. W. Dubensky, D. B. Kanne, M. L. Leong, Ther. Adv. Vaccines 2013, 1, 131–143.
-
(2013)
Ther. Adv. Vaccines
, vol.1
, pp. 131-143
-
-
Dubensky, T.W.1
Kanne, D.B.2
Leong, M.L.3
-
163
-
-
84929705879
-
-
L. Corrales, L. H. Glickman, S. M. McWhirter, D. B. Kanne, K. E. Sivick, G. E. Katibah, S.-R. Woo, E. Lemmens, T. Banda, J. J. Leong, K. Metchette, T. W. Dubensky, T. F. Gajewski, Cell Rep. 2015, 11, 1018–1030;
-
(2015)
Cell Rep.
, vol.11
, pp. 1018-1030
-
-
Corrales, L.1
Glickman, L.H.2
McWhirter, S.M.3
Kanne, D.B.4
Sivick, K.E.5
Katibah, G.E.6
Woo, S.-R.7
Lemmens, E.8
Banda, T.9
Leong, J.J.10
Metchette, K.11
Dubensky, T.W.12
Gajewski, T.F.13
-
165
-
-
80051638135
-
-
P. N. Lara, Jr., J.-Y. Douillard, K. Nakagawa, J. von Pawel, M. J. McKeage, I. Albert, G. Losonczy, M. Reck, D.-S. Heo, X. Fan, A. Fandi, G. Scagliotti, J. Clin. Oncol. 2011, 29, 2965–2971.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 2965-2971
-
-
Lara, P.N.1
Douillard, J.-Y.2
Nakagawa, K.3
von Pawel, J.4
McKeage, M.J.5
Albert, I.6
Losonczy, G.7
Reck, M.8
Heo, D.-S.9
Fan, X.10
Fandi, A.11
Scagliotti, G.12
-
166
-
-
53349177790
-
-
H. Yan, X. Wang, R. KuoLee, W. Chen, Bioorg. Med. Chem. Lett. 2008, 18, 5631–5634.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 5631-5634
-
-
Yan, H.1
Wang, X.2
KuoLee, R.3
Chen, W.4
-
167
-
-
85045260388
-
-
http://www.clinicaltrials.gov NCT02675439, (accessed February 6, 2017);
-
-
-
-
168
-
-
85013124305
-
-
T. R. Vargas, I. Benoit-Lizon, L. Apetoh, Eur. J. Cancer 2017, 75, 86–97;
-
(2017)
Eur. J. Cancer
, vol.75
, pp. 86-97
-
-
Vargas, T.R.1
Benoit-Lizon, I.2
Apetoh, L.3
-
169
-
-
84978419964
-
-
L. Corrales, S. M. McWhirter, T. W. Dubensky, Jr., T. F. Gajewski, J. Clin. Invest. 2016, 126, 2404–2411.
-
(2016)
J. Clin. Invest.
, vol.126
, pp. 2404-2411
-
-
Corrales, L.1
McWhirter, S.M.2
Dubensky, T.W.3
Gajewski, T.F.4
-
170
-
-
85045269969
-
-
https://clinicaltrials.gov NCT03172936, (accessed July 7, 2017).
-
-
-
-
171
-
-
85045234973
-
-
https://clinicaltrials.gov NCT03010176, (accessed July 6, 2017).
-
-
-
-
172
-
-
84989222448
-
-
L. Zitvogel, J. M. Pitt, R. Daillere, M. J. Smyth, G. Kroemer, Nat. Rev. Cancer 2016, 16, 759–773.
-
(2016)
Nat. Rev. Cancer
, vol.16
, pp. 759-773
-
-
Zitvogel, L.1
Pitt, J.M.2
Daillere, R.3
Smyth, M.J.4
Kroemer, G.5
-
173
-
-
84890278138
-
-
K. M. Kokolus, M. L. Capitano, C.-T. Lee, J. W.-L. Eng, J. D. Waight, B. L. Hylander, S. Sexton, C.-C. Hong, C. J. Gordon, S. I. Abrams, E. A. Repasky, Proc. Natl. Acad. Sci. USA 2013, 110, 20176–20181.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 20176-20181
-
-
Kokolus, K.M.1
Capitano, M.L.2
Lee, C.-T.3
Eng, J.W.-L.4
Waight, J.D.5
Hylander, B.L.6
Sexton, S.7
Hong, C.-C.8
Gordon, C.J.9
Abrams, S.I.10
Repasky, E.A.11
|