TNF-α increases production of reactive oxygen species through Cdk5 activation in nociceptive neurons

Frontiers in Physiology

Volumn 9, Issue FEB, 2018, Pages

  Sandoval, Rodrigo ^a   Lazcano, Pablo ^a   Ferrari, Franco ^a   Pinto Pardo, Nicolás ^a,b   González Billault, Christian ^a,c,d   Utreras, Elías ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE LOS ANDES   (Chile)

^c Universidad de Chile and Geroscience Center for Brain Health and Metabolism   (Chile)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Cdk5; NOX; Pain signaling; ROS; TNF

Indexed keywords

CYCLIN DEPENDENT KINASE 5; HYDROGEN PEROXIDE; OXIDOREDUCTASE INHIBITOR; PROTEIN; PROTEIN NOXO1; PROTEIN P35; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; ROSCOVITINE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VAS 2870;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL TRANSPORT; CONTROLLED STUDY; CYTOSOL; EMBRYO; ENZYME ACTIVATION; ENZYME LOCALIZATION; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOUSE; NERVE CELL; NERVE CELL CULTURE; NOCICEPTION; NONHUMAN; P35 GENE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TRIGEMINUS GANGLION;

EID: 85041837361     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2018.00065     Document Type: Article

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