Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity

Pain

Volumn 155, Issue 10, 2014, Pages 2161-2170

  Kallenborn Gerhardt, Wiebke ^a   Hohmann, Stephan W ^a   Syhr, Katharina M J ^a   Schröder, Katrin ^a   Sisignano, Marco ^a   Weigert, Andreas ^b   Lorenz, Jana E ^a   Lu, Ruirui ^a,c   Brüne, Bernhard ^b   Brandes, Ralf P ^a   Geisslinger, Gerd ^a,d   Schmidtko, Achim ^a,c  

^a GOETHE UNIVERSITY MEDICAL SCHOOL   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c UNIVERSITY OF WITTEN HERDECKE   (Germany)

^d FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

Author keywords

Dorsal root ganglion; Knockout mice; Neuropathic pain; Peripheral nerve injury; Reactive oxygen species

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TUMOR NECROSIS FACTOR ALPHA; CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MACROPHAGE; MALE; MOUSE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PERIPHERAL NERVE INJURY; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION; UPREGULATION; ANIMAL; CELL COMMUNICATION; COMPLICATION; HYPERALGESIA; METABOLISM; NEURALGIA; PHYSIOLOGY;

ANIMALS; CELL COMMUNICATION; GANGLIA, SPINAL; HYPERALGESIA; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; NADPH OXIDASE; NEURALGIA; PERIPHERAL NERVE INJURIES; REACTIVE OXYGEN SPECIES; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION;

EID: 84908110359     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2014.08.013     Document Type: Article

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