Targeted overexpression of tumor necrosis factor-α increases cyclin-dependent kinase 5 activity and TRPV1-dependent Ca2+ influx in trigeminal neurons

Pain

Volumn 157, Issue 6, 2016, Pages 1346-1362

  Rozas, Pablo ^a   Lazcano, Pablo ^a   Piña, Ricardo ^b   Cho, Andrew ^c   Terse, Anita ^c   Pertusa, Maria ^b   Madrid, Rodolfo ^b   Gonzalez Billault, Christian ^a   Kulkarni, Ashok B ^c   Utreras, Elias ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Cdk5; Inflammation; Orofacial pain; TNF ; TRPV1

Indexed keywords

CALCIUM; CAPSAICIN; CRE RECOMBINASE; CYCLIN DEPENDENT KINASE 5; EARLY GROWTH RESPONSE FACTOR 1; GLIAL FIBRILLARY ACIDIC PROTEIN; IBA1 PROTEIN; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; NERVE PROTEIN; PROTEIN P35; ROSCOVITINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; TRPV1 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR; VANILLOID RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVERSIVE BEHAVIOR; CALCIUM TRANSPORT; CELL ACTIVATION; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVITY; FACE PAIN; GENETIC RECOMBINATION; HEK293 CELL LINE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY PAIN; MACROPHAGE; MOUSE; MOUTH PAIN; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SATELLITE CELL; SENSITIZATION; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; THERMAL STIMULATION; TRIGEMINUS GANGLION; ANIMAL; GENETICS; METABOLISM; TRANSGENIC MOUSE;

ANIMALS; CALCIUM; CHEMOKINE CCL2; CYCLIN-DEPENDENT KINASE 5; MACROPHAGES; MICE; MICE, TRANSGENIC; SENSORY RECEPTOR CELLS; TRIGEMINAL GANGLION; TRPV CATION CHANNELS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84971287263     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/j.pain.0000000000000527     Document Type: Article

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