NOX4 is an early initiator of neuropathic pain

Experimental Neurology

Volumn 288, Issue , 2017, Pages 94-103

  Geis, Christian ^a,b   Geuss, Eva ^b   Sommer, Claudia ^a   Schmidt, Harald H H W ^c   Kleinschnitz, Christoph ^b,d  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Chronic constriction injury; GKT136901; Neuropathic pain; NOX4

Indexed keywords

2 (2 CHLOROPHENYL) 4 METHYL 5 (PYRIDIN 2 YLMETHYL) 1H PYRAZOLO[4,3 C]PYRIDINE 3,6(2H,5H) DIONE; 3 NITROTYROSINE; BIOLOGICAL MARKER; CYTOKINE; OXIDOREDUCTASE INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; UNCLASSIFIED DRUG; 2-(2-CHLOROPHENYL)-4-METHYL-5-(PYRIDIN-2-YLMETHYL)-1H-PYRAZOLO(4,3-C)PYRIDINE-3,6(2H,5H)-DIONE; MESSENGER RNA; NOX4 PROTEIN, MOUSE; PYRAZOLE DERIVATIVE; PYRIDONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ADULT; ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC CONSTRICTION INJURY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG TREATMENT FAILURE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; KNOCKOUT MOUSE; MALE; MOUSE; MOUSE MODEL; NEUROPATHIC PAIN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; SCIATIC NERVE; SPINAL GANGLION; THERAPEUTIC INDEX; UPREGULATION; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; HYPERALGESIA; METABOLISM; NEURALGIA; PAIN MEASUREMENT; PATHOLOGY; PATHOPHYSIOLOGY; TRANSGENIC MOUSE;

ANALYSIS OF VARIANCE; ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; HYPERALGESIA; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NADPH OXIDASE; NEURALGIA; PAIN MEASUREMENT; PYRAZOLES; PYRIDONES; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SCIATIC NERVE;

EID: 84995878301     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2016.11.008     Document Type: Article

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