Advanced oxidative protein products cause pain hypersensitivity in rats by inducing dorsal root ganglion neurons apoptosis via NADPH oxidase 4/c-jun N-terminal kinase pathways

Frontiers in Molecular Neuroscience

Volumn 10, Issue , 2017, Pages

  Ding, Ruoting ^a   Sun, Baihui ^a   Liu, Zhongyuan ^a   Yao, Xinqiang ^a   Wang, Haiming ^a   Shen, Xing ^a   Jiang, Hui ^a   Chen, Jianting ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Advanced oxidative protein products; Apoptosis; Dorsal root ganglion; Hypersensitivity; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ADVANCED OXIDATION PROTEIN PRODUCT; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CASPASE 9; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; HYPERSENSITIVITY; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; INTRACELLULAR SIGNALING; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; NERVE CELL; NONHUMAN; PAIN; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; TUNEL ASSAY; WESTERN BLOTTING;

EID: 85021411452     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2017.00195     Document Type: Article

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