Aminoglycoside interactions and impacts on the eukaryotic ribosome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 51, 2017, Pages E10899-E10908

  Prokhorova, Irina ^a   Altman, Roger B ^b   Djumagulov, Muminjon ^a   Shrestha, Jaya P ^c   Urzhumtsev, Alexandre ^a,d   Ferguson, Angelica ^b,e   Chang, Cheng Wei Tom ^c   Yusupov, Marat ^a   Blanchard, Scott C ^b,e   Yusupova, Gulnara ^a   Puglisi, Joseph D ^f  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UTAH STATE UNIVERSITY   (United States)

^d UNIVERSITÉ DE LORRAINE   (France)

^e ROCKEFELLER UNIVERSITY   (United States)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aminoglycosides; Protein synthesis; PTC read through; Ribosome; Translation

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC G 418; GENTAMICIN; MESSENGER RNA; METHIONINE TRANSFER RNA; NEOMYCIN; PAROMOMYCIN; PHENYLALANINE TRANSFER RNA; RIBOSOME RNA; RNA 18S; RNA 28S; STREPTOMYCIN; TC 007; TOBRAMYCIN; TRANSFER RNA; UNCLASSIFIED DRUG; AMINOGLYCOSIDE; PROTEIN BINDING;

ARTICLE; CELL INTERACTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING; DRUG BINDING SITE; EUKARYOTIC CELL; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LARGE RIBOSOMAL SUBUNIT; NONHUMAN; PRIORITY JOURNAL; RIBOSOME; RNA BINDING; TRANSLATION REGULATION; TRNA AMINOACYLATION; WHEAT GERM; X RAY CRYSTALLOGRAPHY; BACTERIUM; BINDING SITE; CHEMISTRY; CONFORMATION; DRUG EFFECT; EUKARYOTE; GENETICS; METABOLISM; MOLECULAR MODEL; RIBOSOMAL SUBUNIT;

AMINOGLYCOSIDES; BACTERIA; BINDING SITES; EUKARYOTA; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; RIBOSOME SUBUNITS; RIBOSOMES;

EID: 85038806805     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1715501114     Document Type: Article

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