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Volumn 116, Issue 2, 2007, Pages 156-162

Leishmania major: In vitro and in vivo anti-leishmanial activity of paromomycin ointment (Leshcutan) combined with the immunomodulator Imiquimod

Author keywords

Aldara; Amastigotes; Balb c mice; Imiquimod; IMQ; In vitro and In vivo activity; Leishmania major; Leshcutan; MBCL; Methylbenzethonium chloride; Paromomycin; PR; Promastigotes; Topical treatment

Indexed keywords

IMIQUIMOD; LESHCUTAN; METHYLBENZETHONIUM CHLORIDE; PARAFFIN; PAROMOMYCIN; UNCLASSIFIED DRUG;

EID: 34247130502     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2006.12.004     Document Type: Article
Times cited : (44)

References (32)
  • 1
    • 0028204477 scopus 로고
    • Efficacy of a short course (10 days) of high-dose meglumine antimonate with or without interferon-gamma in treating cutaneous leishmaniasis in Guatemala
    • Arana B.A., Navin T.R., Arana F.E., Berman J.D., and Rosenkaimer F. Efficacy of a short course (10 days) of high-dose meglumine antimonate with or without interferon-gamma in treating cutaneous leishmaniasis in Guatemala. Clinical Infectious Diseases 18 (1994) 381-384
    • (1994) Clinical Infectious Diseases , vol.18 , pp. 381-384
    • Arana, B.A.1    Navin, T.R.2    Arana, F.E.3    Berman, J.D.4    Rosenkaimer, F.5
  • 2
    • 0035211329 scopus 로고    scopus 로고
    • Randomized, controlled, double-blind trial of topical treatment of cutaneous leishmaniasis with paromomycin plus methylbenzethonium chloride ointment in Guatemala
    • Arana B.A., Mendoza C.E., Rizzo N.R., and Kroeger A. Randomized, controlled, double-blind trial of topical treatment of cutaneous leishmaniasis with paromomycin plus methylbenzethonium chloride ointment in Guatemala. American Journal of Tropical Medicine and Hygiene 65 (2001) 466-470
    • (2001) American Journal of Tropical Medicine and Hygiene , vol.65 , pp. 466-470
    • Arana, B.A.1    Mendoza, C.E.2    Rizzo, N.R.3    Kroeger, A.4
  • 5
    • 0025326712 scopus 로고
    • Tumor necrosis factor alpha in combination with interferon-gamma, but not with interleukin 4 activates murine macrophages for elimination of Leishmania major amastigotes
    • Bogdan C., Moll H., Solbach W., and Rollinghoff M. Tumor necrosis factor alpha in combination with interferon-gamma, but not with interleukin 4 activates murine macrophages for elimination of Leishmania major amastigotes. European Journal of Immunology 20 (1990) 1131-1135
    • (1990) European Journal of Immunology , vol.20 , pp. 1131-1135
    • Bogdan, C.1    Moll, H.2    Solbach, W.3    Rollinghoff, M.4
  • 6
    • 0033057209 scopus 로고    scopus 로고
    • Treatment of experimental leishmaniasis with the immunomodulators imiquimod and S-28463: efficacy and mode of action
    • Buates S., and Matlashewski G. Treatment of experimental leishmaniasis with the immunomodulators imiquimod and S-28463: efficacy and mode of action. Journal of Infectious Diseases 179 (1999) 1485-1494
    • (1999) Journal of Infectious Diseases , vol.179 , pp. 1485-1494
    • Buates, S.1    Matlashewski, G.2
  • 8
    • 0023868731 scopus 로고
    • Topical chemotherapy of cutaneous leishmaniasis
    • El-On J., Jacobs G., and Weinrauch L. Topical chemotherapy of cutaneous leishmaniasis. Parasitology Today 4 (1988) 76-81
    • (1988) Parasitology Today , vol.4 , pp. 76-81
    • El-On, J.1    Jacobs, G.2    Weinrauch, L.3
  • 9
    • 0021705093 scopus 로고
    • Development of topical treatment for cutaneous leishmaniasis caused by Leishmania major in experimental animals
    • El-On J., Jacobs G.F., Witztum E., and Greenblatt C.L. Development of topical treatment for cutaneous leishmaniasis caused by Leishmania major in experimental animals. Antimicrobial Agents and Chemotherapy 26 (1984) 745-751
    • (1984) Antimicrobial Agents and Chemotherapy , vol.26 , pp. 745-751
    • El-On, J.1    Jacobs, G.F.2    Witztum, E.3    Greenblatt, C.L.4
  • 10
    • 0025878924 scopus 로고
    • Leishmania major: resistance of promastigotes to paromomycin and susceptibility of amastigotes to paromomycin-methylbenzethonium chloride ointment
    • El-On J., Sulitzeanu A., and Schnur L.F. Leishmania major: resistance of promastigotes to paromomycin and susceptibility of amastigotes to paromomycin-methylbenzethonium chloride ointment. Annals of Tropical Medicine and Parasitology 85 (1991) 323-328
    • (1991) Annals of Tropical Medicine and Parasitology , vol.85 , pp. 323-328
    • El-On, J.1    Sulitzeanu, A.2    Schnur, L.F.3
  • 11
    • 0028169194 scopus 로고
    • Interferon-gamma as an immunological strategy for the treatment of human leishmaniasis
    • Falcoff E., Gimenez L.A., Bernabo J.C., and Bottasso O. Interferon-gamma as an immunological strategy for the treatment of human leishmaniasis. Medicina Buenos Aires 54 (1994) 265-271
    • (1994) Medicina Buenos Aires , vol.54 , pp. 265-271
    • Falcoff, E.1    Gimenez, L.A.2    Bernabo, J.C.3    Bottasso, O.4
  • 14
    • 12344263066 scopus 로고    scopus 로고
    • Activity of paromomycin hydrophilic formulation for topical treatment of infections by Leishmania (Leishmania) amazonensis and Leishmania (Viannia) brziliensis
    • Goncalves G.S., Fernandes A.P., Souza R.C.C., Cardoso J.E., de Oliveira-Silva F., Maciel F.C., Rabello A., and Ferreira L.A.M. Activity of paromomycin hydrophilic formulation for topical treatment of infections by Leishmania (Leishmania) amazonensis and Leishmania (Viannia) brziliensis. Acta Tropica 93 (2005) 161-167
    • (2005) Acta Tropica , vol.93 , pp. 161-167
    • Goncalves, G.S.1    Fernandes, A.P.2    Souza, R.C.C.3    Cardoso, J.E.4    de Oliveira-Silva, F.5    Maciel, F.C.6    Rabello, A.7    Ferreira, L.A.M.8
  • 17
    • 0025609915 scopus 로고
    • Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide
    • Liew F.Y., Li Y., and Millott M.J. Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide. Immunology 145 (1990) 4306-4310
    • (1990) Immunology , vol.145 , pp. 4306-4310
    • Liew, F.Y.1    Li, Y.2    Millott, M.J.3
  • 18
    • 0001663843 scopus 로고
    • The problem of synergism and antagonism of combined drugs
    • Loewe S. The problem of synergism and antagonism of combined drugs. Arzneimittelforschung 3 (1953) 285-320
    • (1953) Arzneimittelforschung , vol.3 , pp. 285-320
    • Loewe, S.1
  • 20
    • 0027241626 scopus 로고
    • Visceral infection caused by Leishmania tropica in veterans of Operation Desert Strom
    • Magill A.J., Grogl M., Gasse R.A., Sun W., and Oster C.N. Visceral infection caused by Leishmania tropica in veterans of Operation Desert Strom. New England Journal of Medicine 328 (1993) 1383-1387
    • (1993) New England Journal of Medicine , vol.328 , pp. 1383-1387
    • Magill, A.J.1    Grogl, M.2    Gasse, R.A.3    Sun, W.4    Oster, C.N.5
  • 22
    • 0034475145 scopus 로고    scopus 로고
    • The role of dentritic cells at the early stages of Leishmania infection
    • Moll H. The role of dentritic cells at the early stages of Leishmania infection. Advances in Experimental Medicine and Biology 479 (2000) 163-173
    • (2000) Advances in Experimental Medicine and Biology , vol.479 , pp. 163-173
    • Moll, H.1
  • 24
    • 0037931526 scopus 로고    scopus 로고
    • Transient effect of topical treatment of cutaneous leishmaniasis with imiquimod
    • Seeberger J., Daoud S., and Pammer J. Transient effect of topical treatment of cutaneous leishmaniasis with imiquimod. International Journal of Dermatology 42 (2003) 576-579
    • (2003) International Journal of Dermatology , vol.42 , pp. 576-579
    • Seeberger, J.1    Daoud, S.2    Pammer, J.3
  • 25
    • 0043163724 scopus 로고    scopus 로고
    • Dentritic cells are responsible for the capacity of CpG oligodeoxynucleotides to act as an adjuvant for protective vaccine immunity against Leishmania major in mice
    • Shah J.A., Darrah P.A., Ambrozak D.R., Turon T.N., Mendez S., Kirman J., Wu C.Y., Glaichenhaus N., and Seder R.A. Dentritic cells are responsible for the capacity of CpG oligodeoxynucleotides to act as an adjuvant for protective vaccine immunity against Leishmania major in mice. Journal of Experimental Medicine 198 (2003) 281-291
    • (2003) Journal of Experimental Medicine , vol.198 , pp. 281-291
    • Shah, J.A.1    Darrah, P.A.2    Ambrozak, D.R.3    Turon, T.N.4    Mendez, S.5    Kirman, J.6    Wu, C.Y.7    Glaichenhaus, N.8    Seder, R.A.9
  • 30
    • 0034533054 scopus 로고    scopus 로고
    • Leishmania major-infected murine langerhans cell-like dentritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous leishmaniasis
    • von Stebut E., Belkaid Y., Nguyen B.V., Cushing M., Sacks D.L., and Udey M.C. Leishmania major-infected murine langerhans cell-like dentritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous leishmaniasis. European Journal of Immunology 30 (2000) 3498-3506
    • (2000) European Journal of Immunology , vol.30 , pp. 3498-3506
    • von Stebut, E.1    Belkaid, Y.2    Nguyen, B.V.3    Cushing, M.4    Sacks, D.L.5    Udey, M.C.6
  • 31
    • 3242665088 scopus 로고    scopus 로고
    • Host genetic background determines whether IL-18 deficiency results in increased susceptibility or resistance to murine Leishmania major
    • Wei X.Q., Niedbala W., Xu D., Luo Z.X., Pollock K.G., and Brewer J.M. Host genetic background determines whether IL-18 deficiency results in increased susceptibility or resistance to murine Leishmania major. Infection Immunology Letters 15 (2004) 35-37
    • (2004) Infection Immunology Letters , vol.15 , pp. 35-37
    • Wei, X.Q.1    Niedbala, W.2    Xu, D.3    Luo, Z.X.4    Pollock, K.G.5    Brewer, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.