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Volumn 7, Issue 1, 2017, Pages

Creation of mutant mice with megabase-sized deletions containing custom-designed breakpoints by means of the CRISPR/Cas9 system

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; CRISPR CAS SYSTEM; DISEASE MODEL; FEMALE; GENE DELETION; GENETICS; MALE; MICROINJECTION; MUTANT MOUSE STRAIN; MUTATION; PLASMID; ZYGOTE;

EID: 85038959265     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-00140-9     Document Type: Article
Times cited : (15)

References (21)
  • 1
    • 0030032063 scopus 로고    scopus 로고
    • Hybrid restriction enzymes: Zinc finger fusions to Fok i cleavage domain
    • Kim, Y. G., Cha, J. & Chandrasegaran, S. Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. Proc. Natl. Acad. Sci. USA 93, 1156-1160 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1156-1160
    • Kim, Y.G.1    Cha, J.2    Chandrasegaran, S.3
  • 2
    • 78951479577 scopus 로고    scopus 로고
    • Targeting DNA double-strand breaks with TAL effector nucleases
    • Christian, M. et al. Targeting DNA double-strand breaks with TAL effector nucleases. Genetics 186, 757-761 (2010).
    • (2010) Genetics , vol.186 , pp. 757-761
    • Christian, M.1
  • 3
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1
  • 4
    • 84873734105 scopus 로고    scopus 로고
    • RNA-guided human genome engineering via Cas9
    • Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339, 823-826 (2013).
    • (2013) Science , vol.339 , pp. 823-826
    • Mali, P.1
  • 5
    • 84903185106 scopus 로고    scopus 로고
    • Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system
    • Inui, M. et al. Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system. Sci. Rep. 4, 5396 (2014).
    • (2014) Sci. Rep. , vol.4 , pp. 5396
    • Inui, M.1
  • 6
    • 84877707375 scopus 로고    scopus 로고
    • One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
    • Wang, H. et al. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153, 910-918 (2013).
    • (2013) Cell , vol.153 , pp. 910-918
    • Wang, H.1
  • 7
    • 84889253665 scopus 로고    scopus 로고
    • Production of Sry knockout mouse using TALEN via oocyte injection
    • Kato, T. et al. Production of Sry knockout mouse using TALEN via oocyte injection. Sci. Rep. 3, 3136 (2013).
    • (2013) Sci. Rep. , vol.3 , pp. 3136
    • Kato, T.1
  • 8
    • 84938945636 scopus 로고    scopus 로고
    • Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice
    • Aida, T. et al. Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice. Genome Biol. 16, 87 (2015).
    • (2015) Genome Biol. , vol.16 , pp. 87
    • Aida, T.1
  • 9
    • 84938932957 scopus 로고    scopus 로고
    • Efficient inversions and duplications of mammalian regulatory DNA elements and gene clusters by CRISPR/Cas9
    • Li, J. et al. Efficient inversions and duplications of mammalian regulatory DNA elements and gene clusters by CRISPR/Cas9. J. Mol. Cell Biol. 4, 284-298 (2015).
    • (2015) J. Mol. Cell Biol. , vol.4 , pp. 284-298
    • Li, J.1
  • 10
    • 84949211352 scopus 로고    scopus 로고
    • Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos
    • Wang, L. et al. Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos. Sci. Rep. 5, 17517 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 17517
    • Wang, L.1
  • 11
    • 84991764274 scopus 로고    scopus 로고
    • Microinjection-based generation of mutant mice with a 0.5 Mb deletion in their genome by the CRISPR/Cas9 system
    • Hara, S. et al. Microinjection-based generation of mutant mice with a 0.5 Mb deletion in their genome by the CRISPR/Cas9 system. J. Reprod. Dev. 62, 531-536 (2016).
    • (2016) J. Reprod. Dev. , vol.62 , pp. 531-536
    • Hara, S.1
  • 12
    • 84941092940 scopus 로고    scopus 로고
    • Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation
    • Mizuno, S. et al. Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation. Sci. Rep. 5, 13632 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 13632
    • Mizuno, S.1
  • 13
    • 84959375643 scopus 로고    scopus 로고
    • Chromosome engineering in zygotes with CRISPR/Cas9
    • Boroviak, K., Doe, B., Banerjee, R., Yang, F. & Bradley, A. Chromosome engineering in zygotes with CRISPR/Cas9. Genesis 54, 78-85 (2016).
    • (2016) Genesis , vol.54 , pp. 78-85
    • Boroviak, K.1    Doe, B.2    Banerjee, R.3    Yang, F.4    Bradley, A.5
  • 14
    • 77950629101 scopus 로고    scopus 로고
    • Familial 1.1 Mb deletion in chromosome Xq22.1 associated with mental retardation and behavioural disorders in female patients
    • Grillo, L. et al. Familial 1.1 Mb deletion in chromosome Xq22.1 associated with mental retardation and behavioural disorders in female patients. Eur. J. Med. Genet. 53, 113-116 (2010).
    • (2010) Eur. J. Med. Genet. , vol.53 , pp. 113-116
    • Grillo, L.1
  • 15
    • 39349116291 scopus 로고    scopus 로고
    • Array based characterization of a terminal deletion involving chromosome subband 15q26.2: An emerging syndrome associated with growth retardation, cardiac defects and developmental delay
    • Davidsson, J., Collin, A., Björkhem, G. & Soller, M. Array based characterization of a terminal deletion involving chromosome subband 15q26.2: an emerging syndrome associated with growth retardation, cardiac defects and developmental delay. BMC Med. Genet. 9, 2 (2008).
    • (2008) BMC Med. Genet. , vol.9 , pp. 2
    • Davidsson, J.1    Collin, A.2    Björkhem, G.3    Soller, M.4
  • 16
    • 71949122225 scopus 로고    scopus 로고
    • Clinical and genomic characterization of distal duplications and deletions of chromosome 4q: Study of two cases and review of the literature
    • Rossi, M. R. et al. Clinical and genomic characterization of distal duplications and deletions of chromosome 4q: study of two cases and review of the literature. Am. J. Med. Genet. A. 149A, 2788-2794 (2009).
    • (2009) Am. J. Med. Genet. A , vol.149 A , pp. 2788-2794
    • Rossi, M.R.1
  • 17
    • 84902958754 scopus 로고    scopus 로고
    • Respiratory failure, cleft palate and epilepsy in the mouse model of human Xq22.1 deletion syndrome
    • Zhou, J. et al. Respiratory failure, cleft palate and epilepsy in the mouse model of human Xq22.1 deletion syndrome. Hum. Mol. Genet. 23, 3823-3829 (2014).
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 3823-3829
    • Zhou, J.1
  • 19
    • 84931291783 scopus 로고    scopus 로고
    • Functional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR-Cas9-mediated mutagenesis
    • Seruggia, D., Fernández, A., Cantero, M., Pelczar, P. & Montoliu, L. Functional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR-Cas9-mediated mutagenesis. Nucleic Acids Res. 43, 4855-4867 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , pp. 4855-4867
    • Seruggia, D.1    Fernández, A.2    Cantero, M.3    Pelczar, P.4    Montoliu, L.5
  • 20
    • 84929142256 scopus 로고    scopus 로고
    • CRISPRdirect: Software for designing CRISPR/Cas guide RNA with reduced off-target sites
    • Naito, Y., Hino, K., Bono, H. & Ui-Tei, K. CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites. Bioinformatics 31, 1120-1123 (2015).
    • (2015) Bioinformatics , vol.31 , pp. 1120-1123
    • Naito, Y.1    Hino, K.2    Bono, H.3    Ui-Tei, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.