메뉴 건너뛰기




Volumn 32, Issue 4, 2017, Pages 520-537.e5

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

(63)  Mackay, Alan a   Burford, Anna a   Carvalho, Diana a   Izquierdo, Elisa a   Fazal Salom, Janat a   Taylor, Kathryn R a,b   Bjerke, Lynn a   Clarke, Matthew a   Vinci, Mara a   Nandhabalan, Meera a   Temelso, Sara a   Popov, Sergey a,c   Molinari, Valeria a   Raman, Pichai d   Waanders, Angela J d   Han, Harry J d   Gupta, Saumya e   Marshall, Lynley f   Zacharoulis, Stergios f   Vaidya, Sucheta f   more..


Author keywords

DIPG; exome; genome; glioblastoma; histone; methylation

Indexed keywords

HISTONE; HISTONE H3; ISOCITRATE DEHYDROGENASE 1; BCOR PROTEIN, HUMAN; CELL CYCLE PROTEIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE III; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; ONCOPROTEIN; REPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

EID: 85030706440     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2017.08.017     Document Type: Article
Times cited : (735)

References (55)
  • 1
    • 84962900469 scopus 로고    scopus 로고
    • Pediatric gliomas as neurodevelopmental disorders
    • Baker, S.J., Ellison, D.W., Gutmann, D.H., Pediatric gliomas as neurodevelopmental disorders. Glia 64 (2015), 879–895.
    • (2015) Glia , vol.64 , pp. 879-895
    • Baker, S.J.1    Ellison, D.W.2    Gutmann, D.H.3
  • 8
    • 84862099805 scopus 로고    scopus 로고
    • arrayMap: a reference resource for genomic copy number imbalances in human malignancies
    • Cai, H., Kumar, N., Baudis, M., arrayMap: a reference resource for genomic copy number imbalances in human malignancies. PLoS One, 7, 2012, e36944.
    • (2012) PLoS One , vol.7 , pp. e36944
    • Cai, H.1    Kumar, N.2    Baudis, M.3
  • 10
    • 84921274493 scopus 로고    scopus 로고
    • The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma
    • Carvalho, D., Mackay, A., Bjerke, L., Grundy, R.G., Lopes, C., Reis, R.M., Jones, C., The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma. Acta Neuropathol. Commun., 2, 2014, 23.
    • (2014) Acta Neuropathol. Commun. , vol.2 , pp. 23
    • Carvalho, D.1    Mackay, A.2    Bjerke, L.3    Grundy, R.G.4    Lopes, C.5    Reis, R.M.6    Jones, C.7
  • 11
    • 84947617209 scopus 로고    scopus 로고
    • Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
    • Castel, D., Philippe, C., Calmon, R., Le Dret, L., Truffaux, N., Boddaert, N., Pages, M., Taylor, K.R., Saulnier, P., Lacroix, L., et al. Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes. Acta Neuropathol. 130 (2015), 815–827.
    • (2015) Acta Neuropathol. , vol.130 , pp. 815-827
    • Castel, D.1    Philippe, C.2    Calmon, R.3    Le Dret, L.4    Truffaux, N.5    Boddaert, N.6    Pages, M.7    Taylor, K.R.8    Saulnier, P.9    Lacroix, L.10
  • 14
    • 84908011711 scopus 로고    scopus 로고
    • Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities
    • Davis, R.J., Welcker, M., Clurman, B.E., Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities. Cancer Cell 26 (2014), 455–464.
    • (2014) Cancer Cell , vol.26 , pp. 455-464
    • Davis, R.J.1    Welcker, M.2    Clurman, B.E.3
  • 17
    • 84919458472 scopus 로고    scopus 로고
    • Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
    • Funato, K., Major, T., Lewis, P.W., Allis, C.D., Tabar, V., Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation. Science 346 (2014), 1529–1533.
    • (2014) Science , vol.346 , pp. 1529-1533
    • Funato, K.1    Major, T.2    Lewis, P.W.3    Allis, C.D.4    Tabar, V.5
  • 20
    • 84991702429 scopus 로고    scopus 로고
    • Recurrent MET fusion genes represent a drug target in pediatric glioblastoma
    • International Cancer Genome Consortium PedBrain Tumor Project. Recurrent MET fusion genes represent a drug target in pediatric glioblastoma. Nat. Med. 22 (2016), 1314–1320.
    • (2016) Nat. Med. , vol.22 , pp. 1314-1320
  • 21
    • 84930188532 scopus 로고    scopus 로고
    • Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma
    • Jones, C., Baker, S.J., Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma. Nat. Rev. Cancer 14 (2014), 651–661.
    • (2014) Nat. Rev. Cancer , vol.14 , pp. 651-661
    • Jones, C.1    Baker, S.J.2
  • 22
    • 84863434843 scopus 로고    scopus 로고
    • Paediatric and adult malignant glioma: close relatives or distant cousins?
    • Jones, C., Perryman, L., Hargrave, D., Paediatric and adult malignant glioma: close relatives or distant cousins?. Nat. Rev. Clin. Oncol. 9 (2012), 400–413.
    • (2012) Nat. Rev. Clin. Oncol. , vol.9 , pp. 400-413
    • Jones, C.1    Perryman, L.2    Hargrave, D.3
  • 25
    • 84939973619 scopus 로고    scopus 로고
    • Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
    • Korshunov, A., Ryzhova, M., Hovestadt, V., Bender, S., Sturm, D., Capper, D., Meyer, J., Schrimpf, D., Kool, M., Northcott, P.A., et al. Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers. Acta Neuropathol. 129 (2015), 669–678.
    • (2015) Acta Neuropathol. , vol.129 , pp. 669-678
    • Korshunov, A.1    Ryzhova, M.2    Hovestadt, V.3    Bender, S.4    Sturm, D.5    Capper, D.6    Meyer, J.7    Schrimpf, D.8    Kool, M.9    Northcott, P.A.10
  • 26
  • 33
    • 80054771090 scopus 로고    scopus 로고
    • Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma
    • Paugh, B.S., Broniscer, A., Qu, C., Miller, C.P., Zhang, J., Tatevossian, R.G., Olson, J.M., Geyer, J.R., Chi, S.N., da Silva, N.S., et al. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. J. Clin. Oncol. 29 (2011), 3999–4006.
    • (2011) J. Clin. Oncol. , vol.29 , pp. 3999-4006
    • Paugh, B.S.1    Broniscer, A.2    Qu, C.3    Miller, C.P.4    Zhang, J.5    Tatevossian, R.G.6    Olson, J.M.7    Geyer, J.R.8    Chi, S.N.9    da Silva, N.S.10
  • 35
    • 84857527038 scopus 로고    scopus 로고
    • Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas
    • Puget, S., Philippe, C., Bax, D.A., Job, B., Varlet, P., Junier, M.P., Andreiuolo, F., Carvalho, D., Reis, R., Guerrini-Rousseau, L., et al. Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas. PLoS One, 7, 2012, e30313.
    • (2012) PLoS One , vol.7 , pp. e30313
    • Puget, S.1    Philippe, C.2    Bax, D.A.3    Job, B.4    Varlet, P.5    Junier, M.P.6    Andreiuolo, F.7    Carvalho, D.8    Reis, R.9    Guerrini-Rousseau, L.10
  • 44
    • 84907044566 scopus 로고    scopus 로고
    • ACVR1 mutations in DIPG: lessons learned from FOP
    • Taylor, K.R., Vinci, M., Bullock, A.N., Jones, C., ACVR1 mutations in DIPG: lessons learned from FOP. Cancer Res. 74 (2014), 4565–4570.
    • (2014) Cancer Res. , vol.74 , pp. 4565-4570
    • Taylor, K.R.1    Vinci, M.2    Bullock, A.N.3    Jones, C.4
  • 46
    • 70349084987 scopus 로고    scopus 로고
    • The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells
    • Temime-Smaali, N., Guittat, L., Sidibe, A., Shin-ya, K., Trentesaux, C., Riou, J.F., The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells. PLoS One, 4, 2009, e6919.
    • (2009) PLoS One , vol.4 , pp. e6919
    • Temime-Smaali, N.1    Guittat, L.2    Sidibe, A.3    Shin-ya, K.4    Trentesaux, C.5    Riou, J.F.6
  • 49
    • 2942650133 scopus 로고    scopus 로고
    • The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
    • Welcker, M., Orian, A., Jin, J., Grim, J.E., Harper, J.W., Eisenman, R.N., Clurman, B.E., The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc. Natl. Acad. Sci. USA 101 (2004), 9085–9090.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9085-9090
    • Welcker, M.1    Orian, A.2    Jin, J.3    Grim, J.E.4    Harper, J.W.5    Eisenman, R.N.6    Clurman, B.E.7
  • 52
    • 84899526966 scopus 로고    scopus 로고
    • The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
    • Wu, G., Diaz, A.K., Paugh, B.S., Rankin, S.L., Ju, B., Li, Y., Zhu, X., Qu, C., Chen, X., Zhang, J., et al. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nat. Genet. 46 (2014), 444–450.
    • (2014) Nat. Genet. , vol.46 , pp. 444-450
    • Wu, G.1    Diaz, A.K.2    Paugh, B.S.3    Rankin, S.L.4    Ju, B.5    Li, Y.6    Zhu, X.7    Qu, C.8    Chen, X.9    Zhang, J.10
  • 54
    • 77954382263 scopus 로고    scopus 로고
    • Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1
    • Yang, J., Bachrati, C.Z., Ou, J., Hickson, I.D., Brown, G.W., Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1. J. Biol. Chem. 285 (2010), 21426–21436.
    • (2010) J. Biol. Chem. , vol.285 , pp. 21426-21436
    • Yang, J.1    Bachrati, C.Z.2    Ou, J.3    Hickson, I.D.4    Brown, G.W.5
  • 55
    • 77950487385 scopus 로고    scopus 로고
    • Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets
    • Zarghooni, M., Bartels, U., Lee, E., Buczkowicz, P., Morrison, A., Huang, A., Bouffet, E., Hawkins, C., Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets. J. Clin. Oncol. 28 (2010), 1337–1344.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 1337-1344
    • Zarghooni, M.1    Bartels, U.2    Lee, E.3    Buczkowicz, P.4    Morrison, A.5    Huang, A.6    Bouffet, E.7    Hawkins, C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.