Human topoisomerase IIIα is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

Journal of Biological Chemistry

Volumn 285, Issue 28, 2010, Pages 21426-21436

  Yang, Jay ^a   Bachrati, Csanad Z ^b   Ou, Jiongwen ^a   Hickson, Ian D ^b   Brown, Grant W ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATENANES; CROSSING OVER; DNA REPLICATIONS; DNA TOPOISOMERASE; HOLLIDAY JUNCTIONS; HOMOLOGOUS RECOMBINATION; HUMAN TOPOISOMERASE; RECOMBINATION INTERMEDIATES; SINGLE-STRANDED DNA; STIMULATORY EFFECTS;

DISSOLUTION; DNA;

GENES;

BLOOM SYNDROME HELICASE; CATENANE; CELL PROTEIN; DECATENASE PROTEIN; HUMAN TOPOISOMERASE IIIALPHA PROTEIN; PROTEIN RMI1; RECQ HELICASE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; CARRIER PROTEIN; CRUCIFORM DNA; DNA TOPOISOMERASE; NUCLEAR PROTEIN; RMI1 PROTEIN, HUMAN; TOPOISOMERASE IIIALPHA;

ARTICLE; CONTROLLED STUDY; DISSOLUTION; DNA REPLICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HOMOLOGOUS RECOMBINATION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; BIOLOGICAL MODEL; CONFORMATION; DNA DAMAGE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; HUMAN GENOME; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE;

CARRIER PROTEINS; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; DNA, CRUCIFORM; DNA, SINGLE-STRANDED; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NUCLEAR PROTEINS; NUCLEIC ACID CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECQ HELICASES; SACCHAROMYCES CEREVISIAE;

EID: 77954382263     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.123216     Document Type: Article

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