-
1
-
-
84924975551
-
Mitochondria in the regulation of innate and adaptive immunity
-
Weinberg, S. E., Sena, L. A., and Chandel, N. S. (2015) Mitochondria in the regulation of innate and adaptive immunity. Immunity 42, 406–417
-
(2015)
Immunity
, vol.42
, pp. 406-417
-
-
Weinberg, S.E.1
Sena, L.A.2
Chandel, N.S.3
-
2
-
-
0033288328
-
Mitochondrial dysfunction in sepsis
-
Singer, M., and Brealey, D. (1999) Mitochondrial dysfunction in sepsis. Biochem. Soc. Symp. 66, 149–166
-
(1999)
Biochem. Soc. Symp.
, vol.66
, pp. 149-166
-
-
Singer, M.1
Brealey, D.2
-
3
-
-
34548176581
-
Mitochondrial function in sepsis: Acute phase versus multiple organ failure
-
Singer, M. (2007) Mitochondrial function in sepsis: acute phase versus multiple organ failure. Crit. Care Med. 35 (9 Suppl), S441–S448
-
(2007)
Crit. Care Med.
, vol.35
, Issue.9
, pp. S441-S448
-
-
Singer, M.1
-
4
-
-
84890115060
-
Polymicrobial sepsis is associated with decreased hepatic oxidative phosphorylation and an altered metabolic profile
-
Whelan, S. P., Carchman, E. H., Kautza, B., Nassour, I., Mollen, K., Escobar, D., Gomez, H., Rosengart, M. A., Shiva, S., and Zuckerbraun, B. S. (2014) Polymicrobial sepsis is associated with decreased hepatic oxidative phosphorylation and an altered metabolic profile. J. Surg. Res. 186, 297–303
-
(2014)
J. Surg. Res.
, vol.186
, pp. 297-303
-
-
Whelan, S.P.1
Carchman, E.H.2
Kautza, B.3
Nassour, I.4
Mollen, K.5
Escobar, D.6
Gomez, H.7
Rosengart, M.A.8
Shiva, S.9
Zuckerbraun, B.S.10
-
5
-
-
10644281080
-
Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome
-
Crouser, E. D. (2004) Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome. Mitochondrion 4, 729–741
-
(2004)
Mitochondrion
, vol.4
, pp. 729-741
-
-
Crouser, E.D.1
-
6
-
-
84890453194
-
Experimental sepsis-induced mitochondrial biogenesis is dependent on autophagy, TLR4, and TLR9 signaling in liver
-
Carchman, E. H., Whelan, S., Loughran, P., Mollen, K., Stratamirovic, S., Shiva, S., Rosengart, M. R., and Zuckerbraun, B. S. (2013) Experimental sepsis-induced mitochondrial biogenesis is dependent on autophagy, TLR4, and TLR9 signaling in liver. FASEB J. 27, 4703–4711
-
(2013)
FASEB J.
, vol.27
, pp. 4703-4711
-
-
Carchman, E.H.1
Whelan, S.2
Loughran, P.3
Mollen, K.4
Stratamirovic, S.5
Shiva, S.6
Rosengart, M.R.7
Zuckerbraun, B.S.8
-
7
-
-
79957446643
-
Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice
-
Carchman, E. H., Rao, J., Loughran, P. A., Rosengart, M. R., and Zuckerbraun, B. S. (2011) Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice. Hepatology 53, 2053–2062
-
(2011)
Hepatology
, vol.53
, pp. 2053-2062
-
-
Carchman, E.H.1
Rao, J.2
Loughran, P.A.3
Rosengart, M.R.4
Zuckerbraun, B.S.5
-
8
-
-
84922776083
-
PINK1/Parkin-mediated mitophagy in mammalian cells
-
Eiyama, A., and Okamoto, K. (2015) PINK1/Parkin-mediated mitophagy in mammalian cells. Curr. Opin. Cell Biol. 33, 95–101
-
(2015)
Curr. Opin. Cell Biol.
, vol.33
, pp. 95-101
-
-
Eiyama, A.1
Okamoto, K.2
-
9
-
-
84867773087
-
Mitophagy: Mechanisms, pathophysiological roles, and analysis
-
Ding, W. X., and Yin, X. M. (2012) Mitophagy: mechanisms, pathophysiological roles, and analysis. Biol. Chem. 393, 547–564
-
(2012)
Biol. Chem.
, vol.393
, pp. 547-564
-
-
Ding, W.X.1
Yin, X.M.2
-
10
-
-
84865544952
-
Mitochondrial fission, fusion, and stress
-
Youle, R. J., and van der Bliek, A. M. (2012) Mitochondrial fission, fusion, and stress. Science 337, 1062–1065
-
(2012)
Science
, vol.337
, pp. 1062-1065
-
-
Youle, R.J.1
Van Der Bliek, A.M.2
-
11
-
-
84858376953
-
Mitochondria: In sickness and in health
-
Nunnari, J., and Suomalainen, A. (2012) Mitochondria: in sickness and in health. Cell 148, 1145–1159
-
(2012)
Cell
, vol.148
, pp. 1145-1159
-
-
Nunnari, J.1
Suomalainen, A.2
-
12
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
He, C., and Klionsky, D. J. (2009) Regulation mechanisms and signaling pathways of autophagy. Annu. Rev. Genet. 43, 67–93
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
13
-
-
34548265278
-
Autophagy and human disease
-
Huang, J., and Klionsky, D. J. (2007) Autophagy and human disease. Cell Cycle 6, 1837–1849
-
(2007)
Cell Cycle
, vol.6
, pp. 1837-1849
-
-
Huang, J.1
Klionsky, D.J.2
-
14
-
-
0037005133
-
Autophagy in yeast: A review of the molecular machinery
-
Huang, W. P., and Klionsky, D. J. (2002) Autophagy in yeast: a review of the molecular machinery. Cell Struct. Funct. 27, 409–420
-
(2002)
Cell Struct. Funct.
, vol.27
, pp. 409-420
-
-
Huang, W.P.1
Klionsky, D.J.2
-
15
-
-
23344446037
-
Autophagy
-
Klionsky, D. J. (2005) Autophagy. Curr. Biol. 15, R282–R283
-
(2005)
Curr. Biol.
, vol.15
, pp. R282-R283
-
-
Klionsky, D.J.1
-
16
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky, D. J., and Emr, S. D. (2000) Autophagy as a regulated pathway of cellular degradation. Science 290, 1717–1721
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
18
-
-
84867273800
-
ROS-induced mitochondrial depolarization initiates PARK2/ PARKIN-dependent mitochondrial degradation by autophagy
-
Wang, Y., Nartiss, Y., Steipe, B., McQuibban, G. A., and Kim, P. K. (2012) ROS-induced mitochondrial depolarization initiates PARK2/ PARKIN-dependent mitochondrial degradation by autophagy. Autophagy 8, 1462–1476
-
(2012)
Autophagy
, vol.8
, pp. 1462-1476
-
-
Wang, Y.1
Nartiss, Y.2
Steipe, B.3
McQuibban, G.A.4
Kim, P.K.5
-
19
-
-
79952324644
-
Regulation of PINK1-Parkin-mediated mitophagy
-
Springer, W., and Kahle, P. J. (2011) Regulation of PINK1-Parkin-mediated mitophagy. Autophagy 7, 266–278
-
(2011)
Autophagy
, vol.7
, pp. 266-278
-
-
Springer, W.1
Kahle, P.J.2
-
20
-
-
56049091236
-
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
-
Kim, Y., Park, J., Kim, S., Song, S., Kwon, S. K., Lee, S. H., Kitada, T., Kim, J. M., and Chung, J. (2008) PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem. Biophys. Res. Commun. 377, 975–980
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 975-980
-
-
Kim, Y.1
Park, J.2
Kim, S.3
Song, S.4
Kwon, S.K.5
Lee, S.H.6
Kitada, T.7
Kim, J.M.8
Chung, J.9
-
21
-
-
84929582993
-
The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications
-
Durcan, T. M., and Fon, E. A. (2015) The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications. Genes Dev. 29, 989–999
-
(2015)
Genes Dev
, vol.29
, pp. 989-999
-
-
Durcan, T.M.1
Fon, E.A.2
-
22
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra, D., Tanaka, A., Suen, D. F., and Youle, R. J. (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 183, 795–803
-
(2008)
J. Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
23
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra, D. P., Jin, S. M., Tanaka, A., Suen, D. F., Gautier, C. A., Shen, J., Cookson, M. R., and Youle, R. J. (2010) PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol. 8, e1000298
-
(2010)
Plos Biol.
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
24
-
-
84869030015
-
Fusion and fission: Interlinked processes critical for mitochondrial health
-
Chan, D. C. (2012) Fusion and fission: interlinked processes critical for mitochondrial health. Annu. Rev. Genet. 46, 265–287
-
(2012)
Annu. Rev. Genet.
, vol.46
, pp. 265-287
-
-
Chan, D.C.1
-
25
-
-
84878918809
-
Mechanisms of mitochondrial fission and fusion
-
Van der Bliek, A. M., Shen, Q., and Kawajiri, S. (2013) Mechanisms of mitochondrial fission and fusion. Cold Spring Harb. Perspect. Biol. 5, a011072
-
(2013)
Cold Spring Harb. Perspect. Biol.
, vol.5
, pp. a011072
-
-
Van der Bliek, A.M.1
Shen, Q.2
Kawajiri, S.3
-
26
-
-
84857977793
-
Mitochondrial quality control and dynamics in Parkinson’s disease
-
McCoy, M. K., and Cookson, M. R. (2012) Mitochondrial quality control and dynamics in Parkinson’s disease. Antioxid. Redox Signal. 16, 869–882
-
(2012)
Antioxid. Redox Signal
, vol.16
, pp. 869-882
-
-
McCoy, M.K.1
Cookson, M.R.2
-
27
-
-
84935909344
-
DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice
-
Shi, S. Y., Lu, S. Y., Sivasubramaniyam, T., Revelo, X. S., Cai, E. P., Luk, C. T., Schroer, S. A., Patel, P., Kim, R. H., Bombardier, E., Quadrilatero, J., Tupling, A. R., Mak, T. W., Winer, D. A., and Woo, M. (2015) DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice. Nat. Commun. 6, 7415
-
(2015)
Nat. Commun.
, vol.6
, pp. 7415
-
-
Shi, S.Y.1
Lu, S.Y.2
Sivasubramaniyam, T.3
Revelo, X.S.4
Cai, E.P.5
Luk, C.T.6
Schroer, S.A.7
Patel, P.8
Kim, R.H.9
Bombardier, E.10
Quadrilatero, J.11
Tupling, A.R.12
Mak, T.W.13
Winer, D.A.14
Woo, M.15
-
28
-
-
84967175489
-
DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission
-
Shimizu, Y., Lambert, J. P., Nicholson, C. K., Kim, J. J., Wolfson, D. W., Cho, H. C., Husain, A., Naqvi, N., Chin, L. S., Li, L., and Calvert, J. W. (2016) DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission. J. Mol. Cell. Cardiol. 97, 56–66
-
(2016)
J. Mol. Cell. Cardiol.
, vol.97
, pp. 56-66
-
-
Shimizu, Y.1
Lambert, J.P.2
Nicholson, C.K.3
Kim, J.J.4
Wolfson, D.W.5
Cho, H.C.6
Husain, A.7
Naqvi, N.8
Chin, L.S.9
Li, L.10
Calvert, J.W.11
-
29
-
-
84992305876
-
DJ-1activatesSIRT1through its direct binding to SIRT1
-
Takahashi-Niki, K., Ganaha, Y., Niki, T., Nakagawa, S., Kato-Ose, I., Iguchi-Ariga,S.M.,and Ariga,H.(2016)DJ-1activatesSIRT1through its direct binding to SIRT1. Biochem. Biophys. Res. Commun. 474, 131–136
-
(2016)
Biochem. Biophys. Res. Commun.
, vol.474
, pp. 131-136
-
-
Takahashi-Niki, K.1
Ganaha, Y.2
Niki, T.3
Nakagawa, S.4
Kato-Ose, I.5
Iguchi-Ariga, S.M.6
Ariga, H.7
-
30
-
-
79956323688
-
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
-
Thomas, K. J., McCoy, M. K., Blackinton, J., Beilina, A., van der Brug, M., Sandebring, A., Miller, D., Maric, D., Cedazo-Minguez, A., and Cookson, M. R. (2011) DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Hum. Mol. Genet. 20, 40–50
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 40-50
-
-
Thomas, K.J.1
McCoy, M.K.2
Blackinton, J.3
Beilina, A.4
Van Der Brug, M.5
Sandebring, A.6
Miller, D.7
Maric, D.8
Cedazo-Minguez, A.9
Cookson, M.R.10
-
31
-
-
79955701611
-
DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
-
McCoy, M. K., and Cookson, M. R. (2011) DJ-1 regulation of mitochondrial function and autophagy through oxidative stress. Autophagy 7, 531–532
-
(2011)
Autophagy
, vol.7
, pp. 531-532
-
-
McCoy, M.K.1
Cookson, M.R.2
-
33
-
-
84865427488
-
Mitochondria as sensors and regulators of calcium signalling
-
Rizzuto, R., De Stefani, D., Raffaello, A., and Mammucari, C. (2012) Mitochondria as sensors and regulators of calcium signalling. Nat. Rev. Mol. Cell Biol. 13, 566–578
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 566-578
-
-
Rizzuto, R.1
De Stefani, D.2
Raffaello, A.3
Mammucari, C.4
-
34
-
-
68649096406
-
Modulation of calcium signalling by mitochondria
-
Walsh, C., Barrow, S., Voronina, S., Chvanov, M., Petersen, O. H., and Tepikin, A. (2009) Modulation of calcium signalling by mitochondria. Biochim. Biophys. Acta 1787, 1374–1382
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 1374-1382
-
-
Walsh, C.1
Barrow, S.2
Voronina, S.3
Chvanov, M.4
Petersen, O.H.5
Tepikin, A.6
-
35
-
-
0034682803
-
Mitochondria shape hormonally induced cytoplasmic calcium oscillations and modulate exocytosis
-
Kaftan, E. J., Xu, T., Abercrombie, R. F., and Hille, B. (2000) Mitochondria shape hormonally induced cytoplasmic calcium oscillations and modulate exocytosis. J. Biol. Chem. 275, 25465–25470
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25465-25470
-
-
Kaftan, E.J.1
Xu, T.2
Abercrombie, R.F.3
Hille, B.4
-
36
-
-
80051946060
-
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
-
Baughman, J. M., Perocchi, F., Girgis, H. S., Plovanich, M., Belcher-Timme, C. A., Sancak, Y., Bao, X. R., Strittmatter, L., Goldberger, O., Bogorad, R. L., Koteliansky, V., and Mootha, V. K. (2011) Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 476, 341–345
-
(2011)
Nature
, vol.476
, pp. 341-345
-
-
Baughman, J.M.1
Perocchi, F.2
Girgis, H.S.3
Plovanich, M.4
Belcher-Timme, C.A.5
Sancak, Y.6
Bao, X.R.7
Strittmatter, L.8
Goldberger, O.9
Bogorad, R.L.10
Koteliansky, V.11
Mootha, V.K.12
-
37
-
-
0030886976
-
Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP kinases
-
Luo, Y., Bond, J. D., and Ingram, V. M. (1997) Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP kinases. Proc. Natl. Acad. Sci. USA 94, 9705–9710
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9705-9710
-
-
Luo, Y.1
Bond, J.D.2
Ingram, V.M.3
-
38
-
-
0034146430
-
Interactions of calcium/calmodulin-dependent protein kinases (CaMK) and extracellular-regulated kinase (ERK) in monocyte adherence and TNFalpha production
-
Rosengart, M. R., Arbabi, S., Garcia, I., and Maier, R. V. (2000) Interactions of calcium/calmodulin-dependent protein kinases (CaMK) and extracellular-regulated kinase (ERK) in monocyte adherence and TNFalpha production. Shock 13, 183–189
-
(2000)
Shock
, vol.13
, pp. 183-189
-
-
Rosengart, M.R.1
Arbabi, S.2
Garcia, I.3
Maier, R.V.4
-
39
-
-
58149308833
-
Calcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages
-
Zhang, X., Wheeler, D., Tang, Y., Guo, L., Shapiro, R. A., Ribar, T. J., Means, A. R., Billiar, T. R., Angus, D. C., and Rosengart, M. R. (2008) Calcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages. J. Immunol. 181, 5015–5023
-
(2008)
J. Immunol.
, vol.181
, pp. 5015-5023
-
-
Zhang, X.1
Wheeler, D.2
Tang, Y.3
Guo, L.4
Shapiro, R.A.5
Ribar, T.J.6
Means, A.R.7
Billiar, T.R.8
Angus, D.C.9
Rosengart, M.R.10
-
40
-
-
56749152348
-
The year in basic science: Calmodulin kinase cascades
-
Means, A. R. (2008) The year in basic science: calmodulin kinase cascades. Mol. Endocrinol. 22, 2759–2765
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 2759-2765
-
-
Means, A.R.1
-
41
-
-
84887108892
-
Calcium supplementation during sepsis exacerbates organ failure and mortality via calcium/ calmodulin-dependent protein kinase kinase signaling
-
Collage, R. D., Howell, G. M., Zhang, X., Stripay, J. L., Lee, J. S., Angus, D. C., and Rosengart, M. R. (2013) Calcium supplementation during sepsis exacerbates organ failure and mortality via calcium/ calmodulin-dependent protein kinase kinase signaling. Crit. Care Med. 41, e352–e360
-
(2013)
Crit. Care Med.
, vol.41
, pp. e352-e360
-
-
Collage, R.D.1
Howell, G.M.2
Zhang, X.3
Stripay, J.L.4
Lee, J.S.5
Angus, D.C.6
Rosengart, M.R.7
-
42
-
-
79961091195
-
Calcium/calmodulin-dependent protein kinase (CaMK) Ialpha mediates the macrophage inflammatory response to sepsis
-
Zhang, X., Guo, L., Collage, R. D., Stripay, J. L., Tsung, A., Lee, J. S., and Rosengart, M. R. (2011) Calcium/calmodulin-dependent protein kinase (CaMK) Ialpha mediates the macrophage inflammatory response to sepsis. J. Leukoc. Biol. 90, 249–261
-
(2011)
J. Leukoc. Biol.
, vol.90
, pp. 249-261
-
-
Zhang, X.1
Guo, L.2
Collage, R.D.3
Stripay, J.L.4
Tsung, A.5
Lee, J.S.6
Rosengart, M.R.7
-
43
-
-
84875442018
-
CaMKIalpha regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation
-
Guo, L., Stripay, J. L., Zhang, X., Collage, R. D., Hulver, M., Carchman, E. H., Howell, G. M., Zuckerbraun, B. S., Lee, J. S., and Rosengart, M. R. (2013) CaMKIalpha regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation. J. Immunol. 190, 3620–3628
-
(2013)
J. Immunol.
, vol.190
, pp. 3620-3628
-
-
Guo, L.1
Stripay, J.L.2
Zhang, X.3
Collage, R.D.4
Hulver, M.5
Carchman, E.H.6
Howell, G.M.7
Zuckerbraun, B.S.8
Lee, J.S.9
Rosengart, M.R.10
-
44
-
-
84907022689
-
CaMKIV-dependent preservation of mTOR expression is required for autophagy during LPS-induced inflammation and acute kidney injury
-
Zhang, X., Howell, G. M., Guo, L., Collage, R. D., Loughran, P. A., Zuckerbraun, B. S., and Rosengart, M. R. (2014) CaMKIV-dependent preservation of mTOR expression is required for autophagy during LPS-induced inflammation and acute kidney injury. J. Immunol. 193, 2405–2415
-
(2014)
J. Immunol.
, vol.193
, pp. 2405-2415
-
-
Zhang, X.1
Howell, G.M.2
Guo, L.3
Collage, R.D.4
Loughran, P.A.5
Zuckerbraun, B.S.6
Rosengart, M.R.7
-
45
-
-
2642531971
-
Calcium activation of ERK mediated by calmodulin kinase I
-
Schmitt, J. M., Wayman, G. A., Nozaki, N., and Soderling, T. R. (2004) Calcium activation of ERK mediated by calmodulin kinase I. J. Biol. Chem. 279, 24064–24072
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24064-24072
-
-
Schmitt, J.M.1
Wayman, G.A.2
Nozaki, N.3
Soderling, T.R.4
-
46
-
-
84880799079
-
Augmenting autophagy to treat acute kidney injury during endotoxemia in mice
-
Howell, G. M., Gomez, H., Collage, R. D., Loughran, P., Zhang, X., Escobar, D. A., Billiar, T. R., Zuckerbraun, B. S., and Rosengart, M. R. (2013) Augmenting autophagy to treat acute kidney injury during endotoxemia in mice. PLoS One 8, e69520
-
(2013)
Plos One
, vol.8
-
-
Howell, G.M.1
Gomez, H.2
Collage, R.D.3
Loughran, P.4
Zhang, X.5
Escobar, D.A.6
Billiar, T.R.7
Zuckerbraun, B.S.8
Rosengart, M.R.9
-
47
-
-
84947570768
-
Inhaled carbon monoxide protects against the development of shock and mitochondrial injury following hemorrhage and resuscitation
-
Gomez, H., Kautza, B., Escobar, D., Nassour, I., Luciano, J., Botero, A. M., Gordon, L., Martinez, S., Holder, A., Ogundele, O., Loughran, P., Rosengart, M. R., Pinsky, M., Shiva, S., and Zuckerbraun, B. S. (2015) Inhaled carbon monoxide protects against the development of shock and mitochondrial injury following hemorrhage and resuscitation. PLoS One 10, e0135032
-
(2015)
Plos One
, vol.10
-
-
Gomez, H.1
Kautza, B.2
Escobar, D.3
Nassour, I.4
Luciano, J.5
Botero, A.M.6
Gordon, L.7
Martinez, S.8
Holder, A.9
Ogundele, O.10
Loughran, P.11
Rosengart, M.R.12
Pinsky, M.13
Shiva, S.14
Zuckerbraun, B.S.15
-
48
-
-
0028838295
-
The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domains
-
Yokokura, H., Picciotto, M. R., Nairn, A. C., and Hidaka, H. (1995) The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domains. J. Biol. Chem. 270, 23851–23859
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23851-23859
-
-
Yokokura, H.1
Picciotto, M.R.2
Nairn, A.C.3
Hidaka, H.4
-
49
-
-
2442616143
-
Cytoplasmic localization of calcium/ calmodulin-dependent protein kinase I-alpha depends on a nuclear export signal in its regulatory domain
-
Stedman, D. R., Uboha, N. V., Stedman, T. T., Nairn, A. C., and Picciotto, M. R. (2004) Cytoplasmic localization of calcium/ calmodulin-dependent protein kinase I-alpha depends on a nuclear export signal in its regulatory domain. FEBS Lett. 566, 275–280
-
(2004)
FEBS Lett.
, vol.566
, pp. 275-280
-
-
Stedman, D.R.1
Uboha, N.V.2
Stedman, T.T.3
Nairn, A.C.4
Picciotto, M.R.5
-
50
-
-
84875545825
-
PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes
-
Loughran, P. A., Stolz, D. B., Barrick, S. R., Wheeler, D. S., Friedman, P. A., Rachubinski, R. A., Watkins, S. C., and Billiar, T. R. (2013) PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes. Nitric Oxide 31, 9–19
-
(2013)
Nitric Oxide
, vol.31
, pp. 9-19
-
-
Loughran, P.A.1
Stolz, D.B.2
Barrick, S.R.3
Wheeler, D.S.4
Friedman, P.A.5
Rachubinski, R.A.6
Watkins, S.C.7
Billiar, T.R.8
-
51
-
-
84922337347
-
Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion
-
Ji, J., Baart, S., Vikulina, A. S., Clark, R. S., Anthonymuthu, T. S., Tyurin, V. A., Du, L., St Croix, C. M., Tyurina, Y. Y., Lewis, J., Skoda, E. M., Kline, A. E., Kochanek, P. M., Wipf, P., Kagan, V. E., and Bayır, H. (2015) Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion. J. Cereb. Blood Flow Metab. 35, 319–328
-
(2015)
J. Cereb. Blood Flow Metab.
, vol.35
, pp. 319-328
-
-
Ji, J.1
Baart, S.2
Vikulina, A.S.3
Clark, R.S.4
Anthonymuthu, T.S.5
Tyurin, V.A.6
Du, L.7
St Croix, C.M.8
Tyurina, Y.Y.9
Lewis, J.10
Skoda, E.M.11
Kline, A.E.12
Kochanek, P.M.13
Wipf, P.14
Kagan, V.E.15
Bayır, H.16
-
52
-
-
84902842760
-
Platelet bioenergetic screen in sickle cell patients reveals mitochondrial complex V inhibition, which contributes to platelet activation
-
Cardenes, N., Corey, C., Geary, L., Jain, S., Zharikov, S., Barge, S., Novelli, E. M., and Shiva, S. (2014) Platelet bioenergetic screen in sickle cell patients reveals mitochondrial complex V inhibition, which contributes to platelet activation. Blood 123, 2864–2872
-
(2014)
Blood
, vol.123
, pp. 2864-2872
-
-
Cardenes, N.1
Corey, C.2
Geary, L.3
Jain, S.4
Zharikov, S.5
Barge, S.6
Novelli, E.M.7
Shiva, S.8
-
53
-
-
84860539187
-
Parkinson’s disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction
-
Wang, X., Petrie, T. G., Liu, Y., Liu, J., Fujioka, H., and Zhu, X. (2012) Parkinson’s disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction. J. Neurochem. 121, 830–839
-
(2012)
J. Neurochem.
, vol.121
, pp. 830-839
-
-
Wang, X.1
Petrie, T.G.2
Liu, Y.3
Liu, J.4
Fujioka, H.5
Zhu, X.6
-
54
-
-
84857869690
-
TLR4-mediated AKT activation is MyD88/TRIF dependent and critical for induction of oxidative phosphorylation and mitochondrial transcription factor A in murine macrophages
-
Bauerfeld, C. P., Rastogi, R., Pirockinaite, G., Lee, I., Hüttemann, M., Monks, B., Birnbaum, M. J., Franchi, L., Nuñez, G., and Samavati, L. (2012) TLR4-mediated AKT activation is MyD88/TRIF dependent and critical for induction of oxidative phosphorylation and mitochondrial transcription factor A in murine macrophages. J. Immunol. 188, 2847–2857
-
(2012)
J. Immunol.
, vol.188
, pp. 2847-2857
-
-
Bauerfeld, C.P.1
Rastogi, R.2
Pirockinaite, G.3
Lee, I.4
Hüttemann, M.5
Monks, B.6
Birnbaum, M.J.7
Franchi, L.8
Nuñez, G.9
Samavati, L.10
-
55
-
-
79251573866
-
Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: A critical role of MKP-1
-
Tucsek, Z., Radnai, B., Racz, B., Debreceni, B., Priber, J. K., Dolowschiak, T., Palkovics, T., Gallyas, F., Jr., Sumegi, B., and Veres, B. (2011) Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: a critical role of MKP-1. J. Leukoc. Biol. 89, 105–111
-
(2011)
J. Leukoc. Biol.
, vol.89
, pp. 105-111
-
-
Tucsek, Z.1
Radnai, B.2
Racz, B.3
Debreceni, B.4
Priber, J.K.5
Dolowschiak, T.6
Palkovics, T.7
Gallyas, F.8
Sumegi, B.9
Veres, B.10
-
56
-
-
84940753412
-
Detection of mitochondrial mass, damage, and reactive oxygen species by flow cytometry
-
pdb.prot086298
-
Puleston, D. (2015) Detection of mitochondrial mass, damage, and reactive oxygen species by flow cytometry. Cold Spring Harb. Protoc. 2015, pdb.prot086298
-
(2015)
Cold Spring Harb. Protoc
, vol.2015
-
-
Puleston, D.1
-
57
-
-
5444224643
-
Efficacy of MitoTracker green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues
-
Pendergrass, W., Wolf, N., and Poot, M. (2004) Efficacy of MitoTracker green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues. Cytometry A 61, 162–169
-
(2004)
Cytometry A
, vol.61
, pp. 162-169
-
-
Pendergrass, W.1
Wolf, N.2
Poot, M.3
-
58
-
-
34250683102
-
Evaluating mitochondrial membrane potential in cells
-
Solaini, G., Sgarbi, G., Lenaz, G., and Baracca, A. (2007) Evaluating mitochondrial membrane potential in cells. Biosci. Rep. 27, 11–21
-
(2007)
Biosci. Rep.
, vol.27
, pp. 11-21
-
-
Solaini, G.1
Sgarbi, G.2
Lenaz, G.3
Baracca, A.4
-
59
-
-
84871891737
-
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
-
Shiba-Fukushima, K., Imai, Y., Yoshida, S., Ishihama, Y., Kanao, T., Sato, S., and Hattori, N. (2012) PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy. Sci. Rep. 2, 1002
-
(2012)
Sci. Rep.
, vol.2
, pp. 1002
-
-
Shiba-Fukushima, K.1
Imai, Y.2
Yoshida, S.3
Ishihama, Y.4
Kanao, T.5
Sato, S.6
Hattori, N.7
-
60
-
-
84881260124
-
Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation
-
Iguchi, M., Kujuro, Y., Okatsu, K., Koyano, F., Kosako, H., Kimura, M., Suzuki, N., Uchiyama, S., Tanaka, K., and Matsuda, N. (2013) Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. J. Biol. Chem. 288, 22019–22032
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 22019-22032
-
-
Iguchi, M.1
Kujuro, Y.2
Okatsu, K.3
Koyano, F.4
Kosako, H.5
Kimura, M.6
Suzuki, N.7
Uchiyama, S.8
Tanaka, K.9
Matsuda, N.10
-
61
-
-
84921925390
-
PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402
-
Aerts, L., Craessaerts, K., De Strooper, B., and Morais, V. A. (2015) PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402. J. Biol. Chem. 290, 2798–2811
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 2798-2811
-
-
Aerts, L.1
Craessaerts, K.2
De Strooper, B.3
Morais, V.A.4
-
62
-
-
36548999695
-
HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling
-
Tsung, A., Klune, J. R., Zhang, X., Jeyabalan, G., Cao, Z., Peng, X., Stolz, D. B., Geller, D. A., Rosengart, M. R., and Billiar, T. R. (2007) HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling. J. Exp. Med. 204, 2913–2923
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2913-2923
-
-
Tsung, A.1
Klune, J.R.2
Zhang, X.3
Jeyabalan, G.4
Cao, Z.5
Peng, X.6
Stolz, D.B.7
Geller, D.A.8
Rosengart, M.R.9
Billiar, T.R.10
-
63
-
-
84879605175
-
Cellular-specific role of Toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice
-
Nace, G. W., Huang, H., Klune, J. R., Eid, R. E., Rosborough, B. R., Korff, S., Li, S., Shapiro, R. A., Stolz, D. B., Sodhi, C. P., Hackam, D. J., Geller, D. A., Billiar, T. R., and Tsung, A. (2013) Cellular-specific role of Toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice. Hepatology 58, 374–387
-
(2013)
Hepatology
, vol.58
, pp. 374-387
-
-
Nace, G.W.1
Huang, H.2
Klune, J.R.3
Eid, R.E.4
Rosborough, B.R.5
Korff, S.6
Li, S.7
Shapiro, R.A.8
Stolz, D.B.9
Sodhi, C.P.10
Hackam, D.J.11
Geller, D.A.12
Billiar, T.R.13
Tsung, A.14
-
64
-
-
28944436247
-
Metabolic failure
-
Singer, M. (2005) Metabolic failure. Crit. Care Med. 33 (Suppl 12), S539–S542
-
(2005)
Crit. Care Med.
, vol.33
, pp. S539-S542
-
-
Singer, M.1
-
65
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
Yang, Z., and Klionsky, D. J. (2010) Mammalian autophagy: core molecular machinery and signaling regulation. Curr. Opin. Cell Biol. 22, 124–131
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
66
-
-
84866142024
-
Emerging role of autophagy in kidney function, diseases and aging
-
Huber, T. B., Edelstein, C. L., Hartleben, B., Inoki, K., Jiang, M., Koya, D., Kume, S., Lieberthal, W., Pallet, N., Quiroga, A., Ravichandran, K., Susztak, K., Yoshida, S., and Dong, Z. (2012) Emerging role of autophagy in kidney function, diseases and aging. Autophagy 8, 1009–1031
-
(2012)
Autophagy
, vol.8
, pp. 1009-1031
-
-
Huber, T.B.1
Edelstein, C.L.2
Hartleben, B.3
Inoki, K.4
Jiang, M.5
Koya, D.6
Kume, S.7
Lieberthal, W.8
Pallet, N.9
Quiroga, A.10
Ravichandran, K.11
Susztak, K.12
Yoshida, S.13
Dong, Z.14
-
67
-
-
33845656956
-
Mitochondrial retrograde signaling
-
Liu, Z., and Butow, R. A. (2006) Mitochondrial retrograde signaling. Annu. Rev. Genet. 40, 159–185
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 159-185
-
-
Liu, Z.1
Butow, R.A.2
-
68
-
-
33846189759
-
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2
-
Høyer-Hansen, M., Bastholm, L., Szyniarowski, P., Campanella, M., Szabadkai, G., Farkas, T., Bianchi, K., Fehrenbacher, N., Elling, F., Rizzuto, R., Mathiasen, I. S., and Jäättelä, M. (2007) Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol. Cell 25, 193–205
-
(2007)
Mol. Cell
, vol.25
, pp. 193-205
-
-
Høyer-Hansen, M.1
Bastholm, L.2
Szyniarowski, P.3
Campanella, M.4
Szabadkai, G.5
Farkas, T.6
Bianchi, K.7
Fehrenbacher, N.8
Elling, F.9
Rizzuto, R.10
Mathiasen, I.S.11
Jäättelä, M.12
-
69
-
-
59049105937
-
DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses
-
Vasseur, S., Afzal, S., Tardivel-Lacombe, J., Park, D. S., Iovanna, J. L., and Mak, T. W. (2009) DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses. Proc. Natl. Acad. Sci. USA 106, 1111–1116
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 1111-1116
-
-
Vasseur, S.1
Afzal, S.2
Tardivel-Lacombe, J.3
Park, D.S.4
Iovanna, J.L.5
Mak, T.W.6
-
70
-
-
77950618226
-
Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway
-
Nakayama, Y., Endo, M., Tsukano, H., Mori, M., Oike, Y., and Gotoh, T. (2010) Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway. J. Biochem. 147, 471–483
-
(2010)
J. Biochem.
, vol.147
, pp. 471-483
-
-
Nakayama, Y.1
Endo, M.2
Tsukano, H.3
Mori, M.4
Oike, Y.5
Gotoh, T.6
-
71
-
-
79955626606
-
Autophagy protects the proximal tubule from degeneration and acute ischemic injury
-
Kimura, T., Takabatake, Y., Takahashi, A., Kaimori, J. Y., Matsui, I., Namba, T., Kitamura, H., Niimura, F., Matsusaka, T., Soga, T., Rakugi, H., and Isaka, Y. (2011) Autophagy protects the proximal tubule from degeneration and acute ischemic injury. J. Am. Soc. Nephrol. 22, 902–913
-
(2011)
J. Am. Soc. Nephrol.
, vol.22
, pp. 902-913
-
-
Kimura, T.1
Takabatake, Y.2
Takahashi, A.3
Kaimori, J.Y.4
Matsui, I.5
Namba, T.6
Kitamura, H.7
Niimura, F.8
Matsusaka, T.9
Soga, T.10
Rakugi, H.11
Isaka, Y.12
-
72
-
-
84863889307
-
Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy
-
Evankovich, J., Zhang, R., Cardinal, J. S., Zhang, L., Chen, J., Huang, H., Beer-Stolz, D., Billiar, T. R., Rosengart, M. R., and Tsung, A. (2012) Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy. Am. J. Physiol. Gastrointest. Liver Physiol. 303, G189–G198
-
(2012)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.303
, pp. G189-G198
-
-
Evankovich, J.1
Zhang, R.2
Cardinal, J.S.3
Zhang, L.4
Chen, J.5
Huang, H.6
Beer-Stolz, D.7
Billiar, T.R.8
Rosengart, M.R.9
Tsung, A.10
-
73
-
-
84940761124
-
Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice
-
Williams, J. A., Ni, H. M., Ding, Y., and Ding, W. X. (2015) Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 309, G324–G340
-
(2015)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.309
, pp. G324-G340
-
-
Williams, J.A.1
Ni, H.M.2
Ding, Y.3
Ding, W.X.4
-
74
-
-
84967194475
-
Triggering of parkin mitochondrial translocation in mitophagy: Implications for liver diseases
-
Eid, N., Ito, Y., and Otsuki, Y. (2016) Triggering of parkin mitochondrial translocation in mitophagy: implications for liver diseases. Front. Pharmacol. 7, 100
-
(2016)
Front. Pharmacol.
, vol.7
, pp. 100
-
-
Eid, N.1
Ito, Y.2
Otsuki, Y.3
-
75
-
-
2942684871
-
The Parkinson’s disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Avilés, R. M., Wilson, M. A., Miller, D. W., Ahmad, R., McLendon, C., Bandyopadhyay, S., Baptista, M. J., Ringe, D., Petsko, G. A., and Cookson, M. R. (2004) The Parkinson’s disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. USA 101, 9103–9108
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9103-9108
-
-
Canet-Avilés, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
76
-
-
77956522541
-
Loss of the Parkinson’s disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
Irrcher, I., Aleyasin, H., Seifert, E. L., Hewitt, S. J., Chhabra, S., Phillips, M., Lutz, A. K., Rousseaux, M. W., Bevilacqua, L., Jahani-Asl, A., Callaghan, S., MacLaurin, J. G., Winklhofer, K. F., Rizzu, P., Rippstein, P., Kim, R. H., Chen, C. X., Fon, E. A., Slack, R. S., Harper, M. E., McBride, H. M., Mak, T. W., and Park, D. S. (2010) Loss of the Parkinson’s disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum. Mol. Genet. 19, 3734–3746
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
Lutz, A.K.7
Rousseaux, M.W.8
Bevilacqua, L.9
Jahani-Asl, A.10
Callaghan, S.11
MacLaurin, J.G.12
Winklhofer, K.F.13
Rizzu, P.14
Rippstein, P.15
Kim, R.H.16
Chen, C.X.17
Fon, E.A.18
Slack, R.S.19
Harper, M.E.20
McBride, H.M.21
Mak, T.W.22
Park, D.S.23
more..
-
77
-
-
77953084081
-
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
-
Hao, L. Y., Giasson, B. I., and Bonini, N. M. (2010) DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function. Proc. Natl. Acad. Sci. USA 107, 9747–9752
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 9747-9752
-
-
Hao, L.Y.1
Giasson, B.I.2
Bonini, N.M.3
-
78
-
-
0037163011
-
Participation of the calcium/calmodulin-dependent kinases in hydrogen peroxide-induced Ikappa B phosphorylation in human T lymphocytes
-
Howe, C. J., LaHair, M. M., Maxwell, J. A., Lee, J. T., Robinson, P. J., Rodriguez-Mora, O., McCubrey, J. A., and Franklin, R. A. (2002) Participation of the calcium/calmodulin-dependent kinases in hydrogen peroxide-induced Ikappa B phosphorylation in human T lymphocytes. J. Biol. Chem. 277, 30469–30476
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30469-30476
-
-
Howe, C.J.1
LaHair, M.M.2
Maxwell, J.A.3
Lee, J.T.4
Robinson, P.J.5
Rodriguez-Mora, O.6
McCubrey, J.A.7
Franklin, R.A.8
-
79
-
-
7244260490
-
Redox regulation of the calcium/calmodulin-dependent protein kinases
-
Howe, C. J., Lahair, M. M., McCubrey, J. A., and Franklin, R. A. (2004) Redox regulation of the calcium/calmodulin-dependent protein kinases. J. Biol. Chem. 279, 44573–44581
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44573-44581
-
-
Howe, C.J.1
Lahair, M.M.2
McCubrey, J.A.3
Franklin, R.A.4
|