DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission

Journal of Molecular and Cellular Cardiology

Volumn 97, Issue , 2016, Pages 56-66

  Shimizu, Yuuki ^a   Lambert, Jonathan P ^a   Nicholson, Chad K ^a   Kim, Joshua J ^a   Wolfson, David W ^b,c   Cho, Hee Cheol ^b,c   Husain, Ahsan ^a   Naqvi, Nawazish ^a   Chin, Li Shen ^a   Li, Lian ^a   Calvert, John W ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

DJ 1; Mitochondrial fission; Myocardial ischemia; SUMOylation

Indexed keywords

DJ 1 PROTEIN; DYNAMIN; DYNAMIN RELATED PROTEIN 1; ENZYME; MESSENGER RNA; PROTEIN SENP1; PROTEIN SENP5; SMALL INTERFERING RNA; SUMO 2 PROTEIN; SUMO 3 PROTEIN; UNCLASSIFIED DRUG; PROTEIN DEGLYCASE DJ-1; REACTIVE OXYGEN METABOLITE;

ADULT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CELL FRACTIONATION; CELL ISOLATION; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; ELECTRON MICROSCOPY; GENETIC TRANSFECTION; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HEART PROTECTION; HYPOXIA; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MALE; MITOCHONDRIAL FISSION; MOLECULAR MECHANICS; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROCESSING; REGULATORY MECHANISM; REOXYGENATION; REPERFUSION INJURY; RNA ISOLATION; SUMOYLATION; WESTERN BLOTTING; WILD TYPE; ANIMAL; BIOPSY; DEFICIENCY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HEART MITOCHONDRION; METABOLISM; MITOCHONDRIAL DYNAMICS; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; OXIDATIVE STRESS; PATHOLOGY; PROTEIN DEGRADATION; RAT;

ANIMALS; BIOPSY; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MITOCHONDRIAL DYNAMICS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PROTEIN DEGLYCASE DJ-1; PROTEOLYSIS; RATS; REACTIVE OXYGEN SPECIES; SUMOYLATION;

EID: 84967175489     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2016.04.008     Document Type: Article

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