TLR4-mediated AKT activation is Myd88/TRIF dependent and critical for induction of oxidative phosphorylation and mitochondrial transcription factor a in murine macrophages

Journal of Immunology

Volumn 188, Issue 6, 2012, Pages 2847-2857

  Bauerfeld, Christian P ^a,e   Rastogi, Ruchi ^b   Pirockinaite, Gaila ^b   Lee, Icksoo ^b   Hüttemann, Maik ^b   Monks, Bobby ^c   Birnbaum, Morris J ^c   Franchi, Luigi ^d   Nunẽz, Gabriel ^d   Samavati, Lobelia ^b  

^a ST JOHN HOSPITAL AND MEDICAL CENTER   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYTOCHROME C OXIDASE; LIPOPOLYSACCHARIDE; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BIOENERGY; BIOGENESIS; BONE MARROW CELL; CELL DEATH; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SYNTHESIS; MACROPHAGE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; UPREGULATION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELL SURVIVAL; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HIGH MOBILITY GROUP PROTEINS; IMMUNOBLOTTING; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MYELOID DIFFERENTIATION FACTOR 88; OXIDATIVE PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84857869690     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102157     Document Type: Article

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