-
1
-
-
84881240163
-
Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): An overview of their mechanisms of formation
-
Vistoli, G.; De Maddis, D.; Cipak, A.; Zarkovic, N.; Carini, M.; Aldini, G. Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation Free Radical Res. 2013, 47 (Sup 1) 3-27 10.3109/10715762.2013.815348
-
(2013)
Free Radical Res.
, vol.47
, Issue.SUP 1
, pp. 3-27
-
-
Vistoli, G.1
De Maddis, D.2
Cipak, A.3
Zarkovic, N.4
Carini, M.5
Aldini, G.6
-
2
-
-
84907485776
-
Mechanistic insights in glycation-induced protein aggregation
-
Adrover, M.; Marino, L.; Sanchis, P.; Pauwels, K.; Kraan, Y.; Lebrun, P.; Vilanova, B.; Munoz, F.; Broersen, K.; Donoso, J. Mechanistic insights in glycation-induced protein aggregation Biomacromolecules 2014, 15, 3449-3462 10.1021/bm501077j
-
(2014)
Biomacromolecules
, vol.15
, pp. 3449-3462
-
-
Adrover, M.1
Marino, L.2
Sanchis, P.3
Pauwels, K.4
Kraan, Y.5
Lebrun, P.6
Vilanova, B.7
Munoz, F.8
Broersen, K.9
Donoso, J.10
-
3
-
-
0032427387
-
Advanced glycation end products induce crosslinking of collagen in vitro
-
Sajithlal, G. B.; Chithra, P.; Chandrakasan, G. Advanced glycation end products induce crosslinking of collagen in vitro Biochim. Biophys. Acta, Mol. Basis Dis. 1998, 1407, 215-224 10.1016/S0925-4439(98)00043-X
-
(1998)
Biochim. Biophys. Acta, Mol. Basis Dis.
, vol.1407
, pp. 215-224
-
-
Sajithlal, G.B.1
Chithra, P.2
Chandrakasan, G.3
-
4
-
-
84963872501
-
Basic and Clinical Research Against Advanced Glycation End Products (AGEs): New Compounds to Tackle Cardiovascular Disease and Diabetic Complications
-
Nenna, A.; Spadaccio, C.; Lusini, M.; Ulianich, L.; Chello, M.; Nappi, F. Basic and Clinical Research Against Advanced Glycation End Products (AGEs): New Compounds to Tackle Cardiovascular Disease and Diabetic Complications Recent Pat. Cardiovasc. Drug Discovery 2015, 10, 10-33 10.2174/1574890110666151104120039
-
(2015)
Recent Pat. Cardiovasc. Drug Discovery
, vol.10
, pp. 10-33
-
-
Nenna, A.1
Spadaccio, C.2
Lusini, M.3
Ulianich, L.4
Chello, M.5
Nappi, F.6
-
5
-
-
84862780458
-
Advanced glycation end products and neurodegenerative diseases: Mechanisms and perspective
-
Li, J.; Liu, D.; Sun, L.; Lu, Y.; Zhang, Z. Advanced glycation end products and neurodegenerative diseases: mechanisms and perspective J. Neurol. Sci. 2012, 317, 1-5 10.1016/j.jns.2012.02.018
-
(2012)
J. Neurol. Sci.
, vol.317
, pp. 1-5
-
-
Li, J.1
Liu, D.2
Sun, L.3
Lu, Y.4
Zhang, Z.5
-
6
-
-
17744407388
-
Advanced glycation end products and receptor for advanced glycation end products in AA amyloidosis
-
Rocken, C.; Kientsch-Engel, R.; Mansfeld, S.; Stix, B.; Stubenrauch, K.; Weigle, B.; Buhling, F.; Schwan, M.; Saeger, W. Advanced glycation end products and receptor for advanced glycation end products in AA amyloidosis Am. J. Pathol. 2003, 162, 1213-1220 10.1016/S0002-9440(10)63917-X
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1213-1220
-
-
Rocken, C.1
Kientsch-Engel, R.2
Mansfeld, S.3
Stix, B.4
Stubenrauch, K.5
Weigle, B.6
Buhling, F.7
Schwan, M.8
Saeger, W.9
-
7
-
-
64749107607
-
RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation
-
Sparvero, L. J.; Asafu-Adjei, D.; Kang, R.; Tang, D.; Amin, N.; Im, J.; Rutledge, R.; Lin, B.; Amoscato, A. A.; Zeh, H. J.; Lotze, M. T. RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation J. Transl. Med. 2009, 7, 17 10.1186/1479-5876-7-17
-
(2009)
J. Transl. Med.
, vol.7
, pp. 17
-
-
Sparvero, L.J.1
Asafu-Adjei, D.2
Kang, R.3
Tang, D.4
Amin, N.5
Im, J.6
Rutledge, R.7
Lin, B.8
Amoscato, A.A.9
Zeh, H.J.10
Lotze, M.T.11
-
8
-
-
26444478269
-
Advanced glycation end products and RAGE: A common thread in aging, diabetes, neurodegeneration, and inflammation
-
Ramasamy, R.; Vannucci, S. J.; Yan, S. S. D.; Herold, K.; Yan, S. F.; Schmidt, A. M. Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation Glycobiology 2005, 15, 16R-28R 10.1093/glycob/cwi053
-
(2005)
Glycobiology
, vol.15
, pp. 16R-28R
-
-
Ramasamy, R.1
Vannucci, S.J.2
Yan, S.S.D.3
Herold, K.4
Yan, S.F.5
Schmidt, A.M.6
-
9
-
-
84953931462
-
RAGE axis in neuroinflammation, neurodegeneration and its emerging role in the pathogenesis of amyotrophic lateral sclerosis
-
Ray, R.; Juranek, J. K.; Rai, V. RAGE axis in neuroinflammation, neurodegeneration and its emerging role in the pathogenesis of amyotrophic lateral sclerosis Neurosci. Biobehav. Rev. 2016, 62, 48-55 10.1016/j.neubiorev.2015.12.006
-
(2016)
Neurosci. Biobehav. Rev.
, vol.62
, pp. 48-55
-
-
Ray, R.1
Juranek, J.K.2
Rai, V.3
-
10
-
-
0026659883
-
Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
-
Neeper, M.; Schmidt, A. M.; Brett, J.; Yan, S. D.; Wang, F.; Pan, Y. C.; Elliston, K.; Stern, D.; Shaw, A. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins J. Biol. Chem. 1992, 267, 14998-15004
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 14998-15004
-
-
Neeper, M.1
Schmidt, A.M.2
Brett, J.3
Yan, S.D.4
Wang, F.5
Pan, Y.C.6
Elliston, K.7
Stern, D.8
Shaw, A.9
-
11
-
-
25144467605
-
Expression profiling of endogenous secretory receptor for advanced glycation end products in human organs
-
Cheng, C.; Tsuneyama, K.; Kominami, R.; Shinohara, H.; Sakurai, S.; Yonekura, H.; Watanabe, T.; Takano, Y.; Yamamoto, H.; Yamamoto, Y. Expression profiling of endogenous secretory receptor for advanced glycation end products in human organs Mod. Pathol. 2005, 18, 1385-1396 10.1038/modpathol.3800450
-
(2005)
Mod. Pathol.
, vol.18
, pp. 1385-1396
-
-
Cheng, C.1
Tsuneyama, K.2
Kominami, R.3
Shinohara, H.4
Sakurai, S.5
Yonekura, H.6
Watanabe, T.7
Takano, Y.8
Yamamoto, H.9
Yamamoto, Y.10
-
12
-
-
0033848466
-
Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease
-
Tanji, N.; Markowitz, G. S.; Fu, C.; Kislinger, T.; Taguchi, A.; Pischetsrieder, M.; Stern, D.; Schmidt, A. M.; D'Agati, V. D. Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease J. Am. Soc. Nephrol. 2000, 11, 1656-1666
-
(2000)
J. Am. Soc. Nephrol.
, vol.11
, pp. 1656-1666
-
-
Tanji, N.1
Markowitz, G.S.2
Fu, C.3
Kislinger, T.4
Taguchi, A.5
Pischetsrieder, M.6
Stern, D.7
Schmidt, A.M.8
D'Agati, V.D.9
-
13
-
-
18244381813
-
Plasma levels of soluble receptor for advanced glycation end products and coronary artery disease in nondiabetic men
-
Falcone, C.; Emanuele, E.; D'Angelo, A.; Buzzi, M. P.; Belvito, C.; Cuccia, M.; Geroldi, D. Plasma levels of soluble receptor for advanced glycation end products and coronary artery disease in nondiabetic men Arterioscler., Thromb., Vasc. Biol. 2005, 25, 1032-1037 10.1161/01.ATV.0000160342.20342.00
-
(2005)
Arterioscler., Thromb., Vasc. Biol.
, vol.25
, pp. 1032-1037
-
-
Falcone, C.1
Emanuele, E.2
D'Angelo, A.3
Buzzi, M.P.4
Belvito, C.5
Cuccia, M.6
Geroldi, D.7
-
14
-
-
27744510124
-
Circulating levels of soluble receptor for advanced glycation end products in Alzheimer disease and vascular dementia
-
Emanuele, E.; D'Angelo, A.; Tomaino, C.; Binetti, G.; Ghidoni, R.; Politi, P.; Bernardi, L.; Maletta, R.; Bruni, A. C.; Geroldi, D. Circulating levels of soluble receptor for advanced glycation end products in Alzheimer disease and vascular dementia Arch. Neurol. 2005, 62, 1734-1736 10.1001/archneur.62.11.1734
-
(2005)
Arch. Neurol.
, vol.62
, pp. 1734-1736
-
-
Emanuele, E.1
D'Angelo, A.2
Tomaino, C.3
Binetti, G.4
Ghidoni, R.5
Politi, P.6
Bernardi, L.7
Maletta, R.8
Bruni, A.C.9
Geroldi, D.10
-
15
-
-
77955769241
-
The receptor RAGE: Bridging inflammation and cancer
-
Riehl, A.; Nemeth, J.; Angel, P.; Hess, J. The receptor RAGE: Bridging inflammation and cancer Cell Commun. Signaling 2009, 7, 12 10.1186/1478-811X-7-12
-
(2009)
Cell Commun. Signaling
, vol.7
, pp. 12
-
-
Riehl, A.1
Nemeth, J.2
Angel, P.3
Hess, J.4
-
16
-
-
84930818072
-
RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment
-
Nasser, M. W.; Wani, N. A.; Ahirwar, D. K.; Powell, C. A.; Ravi, J.; Elbaz, M.; Zhao, H.; Padilla, L.; Zhang, X.; Shilo, K.; Ostrowski, M.; Shapiro, C.; Carson, W. E., 3rd; Ganju, R. K. RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment Cancer Res. 2015, 75, 974-985 10.1158/0008-5472.CAN-14-2161
-
(2015)
Cancer Res.
, vol.75
, pp. 974-985
-
-
Nasser, M.W.1
Wani, N.A.2
Ahirwar, D.K.3
Powell, C.A.4
Ravi, J.5
Elbaz, M.6
Zhao, H.7
Padilla, L.8
Zhang, X.9
Shilo, K.10
Ostrowski, M.11
Shapiro, C.12
Carson, W.E.13
Ganju, R.K.14
-
17
-
-
84859723641
-
A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease
-
Deane, R.; Singh, I.; Sagare, A. P.; Bell, R. D.; Ross, N. T.; LaRue, B.; Love, R.; Perry, S.; Paquette, N.; Deane, R. J.; Thiyagarajan, M.; Zarcone, T.; Fritz, G.; Friedman, A. E.; Miller, B. L.; Zlokovic, B. V. A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease J. Clin. Invest. 2012, 122, 1377-1392 10.1172/JCI58642
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1377-1392
-
-
Deane, R.1
Singh, I.2
Sagare, A.P.3
Bell, R.D.4
Ross, N.T.5
LaRue, B.6
Love, R.7
Perry, S.8
Paquette, N.9
Deane, R.J.10
Thiyagarajan, M.11
Zarcone, T.12
Fritz, G.13
Friedman, A.E.14
Miller, B.L.15
Zlokovic, B.V.16
-
18
-
-
84962245713
-
Synthesis and Evaluation of [(18)F]RAGER: A First Generation Small-Molecule PET Radioligand Targeting the Receptor for Advanced Glycation Endproducts
-
Cary, B. P.; Brooks, A. F.; Fawaz, M. V.; Drake, L. R.; Desmond, T. J.; Sherman, P.; Quesada, C. A.; Scott, P. J. Synthesis and Evaluation of [(18)F]RAGER: A First Generation Small-Molecule PET Radioligand Targeting the Receptor for Advanced Glycation Endproducts ACS Chem. Neurosci. 2016, 7, 391-398 10.1021/acschemneuro.5b00319
-
(2016)
ACS Chem. Neurosci.
, vol.7
, pp. 391-398
-
-
Cary, B.P.1
Brooks, A.F.2
Fawaz, M.V.3
Drake, L.R.4
Desmond, T.J.5
Sherman, P.6
Quesada, C.A.7
Scott, P.J.8
-
19
-
-
84902173668
-
Alzheimer's Disease Cooperative, S. Clinical trial of an inhibitor of RAGE-Abeta interactions in Alzheimer disease
-
Galasko, D.; Bell, J.; Mancuso, J. Y.; Kupiec, J. W.; Sabbagh, M. N.; van Dyck, C.; Thomas, R. G.; Aisen, P. S. Alzheimer's Disease Cooperative, S. Clinical trial of an inhibitor of RAGE-Abeta interactions in Alzheimer disease Neurology 2014, 82, 1536-1542 10.1212/WNL.0000000000000364
-
(2014)
Neurology
, vol.82
, pp. 1536-1542
-
-
Galasko, D.1
Bell, J.2
Mancuso, J.Y.3
Kupiec, J.W.4
Sabbagh, M.N.5
Van Dyck, C.6
Thomas, R.G.7
Aisen, P.S.8
-
20
-
-
85029500599
-
-
UniProt, (accessed April 6, 2017)
-
UniProtKB-Q15109 (RAGE-HUMAN); UniProt, 2017; http://www.uniprot.org/uniprot/Q15109 (accessed April 6, 2017).
-
(2017)
UniProtKB - Q15109 (RAGE-HUMAN)
-
-
-
21
-
-
84889651840
-
Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products
-
Yatime, L.; Andersen, G. R. Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products FEBS J. 2013, 280, 6556-6568 10.1111/febs.12556
-
(2013)
FEBS J.
, vol.280
, pp. 6556-6568
-
-
Yatime, L.1
Andersen, G.R.2
-
22
-
-
79955825348
-
Advanced glycation end product recognition by the receptor for AGEs
-
Xue, J.; Rai, V.; Singer, D.; Chabierski, S.; Xie, J.; Reverdatto, S.; Burz, D. S.; Schmidt, A. M.; Hoffmann, R.; Shekhtman, A. Advanced glycation end product recognition by the receptor for AGEs Structure 2011, 19, 722-732 10.1016/j.str.2011.02.013
-
(2011)
Structure
, vol.19
, pp. 722-732
-
-
Xue, J.1
Rai, V.2
Singer, D.3
Chabierski, S.4
Xie, J.5
Reverdatto, S.6
Burz, D.S.7
Schmidt, A.M.8
Hoffmann, R.9
Shekhtman, A.10
-
23
-
-
77957775497
-
Structural basis for ligand recognition and activation of RAGE
-
Koch, M.; Chitayat, S.; Dattilo, B. M.; Schiefner, A.; Diez, J.; Chazin, W. J.; Fritz, G. Structural basis for ligand recognition and activation of RAGE Structure 2010, 18, 1342-1352 10.1016/j.str.2010.05.017
-
(2010)
Structure
, vol.18
, pp. 1342-1352
-
-
Koch, M.1
Chitayat, S.2
Dattilo, B.M.3
Schiefner, A.4
Diez, J.5
Chazin, W.J.6
Fritz, G.7
-
24
-
-
34250171731
-
The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units
-
Dattilo, B. M.; Fritz, G.; Leclerc, E.; vander Kooi, C. W.; Heizmann, C. W.; Chazin, W. J. The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units Biochemistry 2007, 46, 6957-6970 10.1021/bi7003735
-
(2007)
Biochemistry
, vol.46
, pp. 6957-6970
-
-
Dattilo, B.M.1
Fritz, G.2
Leclerc, E.3
Vander Kooi, C.W.4
Heizmann, C.W.5
Chazin, W.J.6
-
25
-
-
45549097081
-
Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity
-
Sturchler, E.; Galichet, A.; Weibel, M.; Leclerc, E.; Heizmann, C. W. Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity J. Neurosci. 2008, 28, 5149-5158 10.1523/JNEUROSCI.4878-07.2008
-
(2008)
J. Neurosci.
, vol.28
, pp. 5149-5158
-
-
Sturchler, E.1
Galichet, A.2
Weibel, M.3
Leclerc, E.4
Heizmann, C.W.5
-
26
-
-
84901468550
-
The receptor for advanced glycation end products (RAGE) specifically recognizes methylglyoxal-derived AGEs
-
Xue, J.; Ray, R.; Singer, D.; Bohme, D.; Burz, D. S.; Rai, V.; Hoffmann, R.; Shekhtman, A. The receptor for advanced glycation end products (RAGE) specifically recognizes methylglyoxal-derived AGEs Biochemistry 2014, 53, 3327-3335 10.1021/bi500046t
-
(2014)
Biochemistry
, vol.53
, pp. 3327-3335
-
-
Xue, J.1
Ray, R.2
Singer, D.3
Bohme, D.4
Burz, D.S.5
Rai, V.6
Hoffmann, R.7
Shekhtman, A.8
-
27
-
-
0028851635
-
The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
-
Hori, O.; Brett, J.; Slattery, T.; Cao, R.; Zhang, J.; Chen, J. X.; Nagashima, M.; Lundh, E. R.; Vijay, S.; Nitecki, D. et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system J. Biol. Chem. 1995, 270, 25752-25761 10.1074/jbc.270.43.25752
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25752-25761
-
-
Hori, O.1
Brett, J.2
Slattery, T.3
Cao, R.4
Zhang, J.5
Chen, J.X.6
Nagashima, M.7
Lundh, E.R.8
Vijay, S.9
Nitecki, D.10
-
28
-
-
55249118389
-
Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE)
-
Xie, J.; Reverdatto, S.; Frolov, A.; Hoffmann, R.; Burz, D. S.; Shekhtman, A. Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE) J. Biol. Chem. 2008, 283, 27255-27269 10.1074/jbc.M801622200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27255-27269
-
-
Xie, J.1
Reverdatto, S.2
Frolov, A.3
Hoffmann, R.4
Burz, D.S.5
Shekhtman, A.6
-
29
-
-
33947510205
-
Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches
-
Xie, J.; Burz, D. S.; He, W.; Bronstein, I. B.; Lednev, I.; Shekhtman, A. Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches J. Biol. Chem. 2007, 282, 4218-4231 10.1074/jbc.M608888200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4218-4231
-
-
Xie, J.1
Burz, D.S.2
He, W.3
Bronstein, I.B.4
Lednev, I.5
Shekhtman, A.6
-
30
-
-
77954891042
-
Homodimerization is essential for the receptor for advanced glycation end products (RAGE)-mediated signal transduction
-
Zong, H.; Madden, A.; Ward, M.; Mooney, M. H.; Elliott, C. T.; Stitt, A. W. Homodimerization is essential for the receptor for advanced glycation end products (RAGE)-mediated signal transduction J. Biol. Chem. 2010, 285, 23137-23146 10.1074/jbc.M110.133827
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 23137-23146
-
-
Zong, H.1
Madden, A.2
Ward, M.3
Mooney, M.H.4
Elliott, C.T.5
Stitt, A.W.6
-
31
-
-
84880555698
-
Stable RAGE-heparan sulfate complexes are essential for signal transduction
-
Xu, D.; Young, J. H.; Krahn, J. M.; Song, D.; Corbett, K. D.; Chazin, W. J.; Pedersen, L. C.; Esko, J. D. Stable RAGE-heparan sulfate complexes are essential for signal transduction ACS Chem. Biol. 2013, 8, 1611-1620 10.1021/cb4001553
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 1611-1620
-
-
Xu, D.1
Young, J.H.2
Krahn, J.M.3
Song, D.4
Corbett, K.D.5
Chazin, W.J.6
Pedersen, L.C.7
Esko, J.D.8
-
32
-
-
64149108074
-
Impact of COPD severity on physical disability and daily living activities: EDIP-EPOC i and EDIP-EPOC II studies
-
Rodriguez Gonzalez-Moro, J. M.; de Lucas Ramos, P.; Izquierdo Alonso, J. L.; Lopez-Muniz Ballesteros, B.; Anton Diaz, E.; Ribera, X.; Martin, A. Impact of COPD severity on physical disability and daily living activities: EDIP-EPOC I and EDIP-EPOC II studies Int. J. Clin. Pract. 2009, 63, 742-750 10.1111/j.1742-1241.2009.02040.x
-
(2009)
Int. J. Clin. Pract.
, vol.63
, pp. 742-750
-
-
Rodriguez Gonzalez-Moro, J.M.1
De Lucas Ramos, P.2
Izquierdo Alonso, J.L.3
Lopez-Muniz Ballesteros, B.4
Anton Diaz, E.5
Ribera, X.6
Martin, A.7
-
33
-
-
79960959115
-
TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding
-
Sakaguchi, M.; Murata, H.; Yamamoto, K.; Ono, T.; Sakaguchi, Y.; Motoyama, A.; Hibino, T.; Kataoka, K.; Huh, N. H. TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding PLoS One 2011, 6, e23132 10.1371/journal.pone.0023132
-
(2011)
PLoS One
, vol.6
, pp. e23132
-
-
Sakaguchi, M.1
Murata, H.2
Yamamoto, K.3
Ono, T.4
Sakaguchi, Y.5
Motoyama, A.6
Hibino, T.7
Kataoka, K.8
Huh, N.H.9
-
34
-
-
84856873812
-
Signal transduction in receptor for advanced glycation end products (RAGE): Solution structure of C-terminal rage (ctRAGE) and its binding to mDia1
-
Rai, V.; Maldonado, A. Y.; Burz, D. S.; Reverdatto, S.; Schmidt, A. M.; Shekhtman, A. Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1 J. Biol. Chem. 2012, 287, 5133-5144 10.1074/jbc.M111.277731
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 5133-5144
-
-
Rai, V.1
Maldonado, A.Y.2
Burz, D.S.3
Reverdatto, S.4
Schmidt, A.M.5
Shekhtman, A.6
-
35
-
-
84960105896
-
Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction
-
Manigrasso, M. B.; Pan, J.; Rai, V.; Zhang, J.; Reverdatto, S.; Quadri, N.; DeVita, R. J.; Ramasamy, R.; Shekhtman, A.; Schmidt, A. M. Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction Sci. Rep. 2016, 6, 22450 10.1038/srep22450
-
(2016)
Sci. Rep.
, vol.6
, pp. 22450
-
-
Manigrasso, M.B.1
Pan, J.2
Rai, V.3
Zhang, J.4
Reverdatto, S.5
Quadri, N.6
DeVita, R.J.7
Ramasamy, R.8
Shekhtman, A.9
Schmidt, A.M.10
-
36
-
-
0142039004
-
The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site
-
Ishihara, K.; Tsutsumi, K.; Kawane, S.; Nakajima, M.; Kasaoka, T. The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site FEBS Lett. 2003, 550, 107-113 10.1016/S0014-5793(03)00846-9
-
(2003)
FEBS Lett.
, vol.550
, pp. 107-113
-
-
Ishihara, K.1
Tsutsumi, K.2
Kawane, S.3
Nakajima, M.4
Kasaoka, T.5
-
37
-
-
57749122052
-
Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42
-
Hudson, B. I.; Kalea, A. Z.; Del Mar Arriero, M.; Harja, E.; Boulanger, E.; D'Agati, V.; Schmidt, A. M. Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42 J. Biol. Chem. 2008, 283, 34457-34468 10.1074/jbc.M801465200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34457-34468
-
-
Hudson, B.I.1
Kalea, A.Z.2
Del Mar Arriero, M.3
Harja, E.4
Boulanger, E.5
D'Agati, V.6
Schmidt, A.M.7
-
38
-
-
0033538569
-
Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways
-
Huttunen, H. J.; Fages, C.; Rauvala, H. Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways J. Biol. Chem. 1999, 274, 19919-19924 10.1074/jbc.274.28.19919
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19919-19924
-
-
Huttunen, H.J.1
Fages, C.2
Rauvala, H.3
-
39
-
-
38149078193
-
Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice
-
Harja, E.; Bu, D. X.; Hudson, B. I.; Chang, J. S.; Shen, X.; Hallam, K.; Kalea, A. Z.; Lu, Y.; Rosario, R. H.; Oruganti, S.; Nikolla, Z.; Belov, D.; Lalla, E.; Ramasamy, R.; Yan, S. F.; Schmidt, A. M. Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice J. Clin. Invest. 2008, 118, 183-194 10.1172/JCI32703
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 183-194
-
-
Harja, E.1
Bu, D.X.2
Hudson, B.I.3
Chang, J.S.4
Shen, X.5
Hallam, K.6
Kalea, A.Z.7
Lu, Y.8
Rosario, R.H.9
Oruganti, S.10
Nikolla, Z.11
Belov, D.12
Lalla, E.13
Ramasamy, R.14
Yan, S.F.15
Schmidt, A.M.16
-
40
-
-
84892506431
-
Alternative splicing of the RAGE cytoplasmic domain regulates cell signaling and function
-
Jules, J.; Maiguel, D.; Hudson, B. I. Alternative splicing of the RAGE cytoplasmic domain regulates cell signaling and function PLoS One 2013, 8, e78267 10.1371/journal.pone.0078267
-
(2013)
PLoS One
, vol.8
, pp. e78267
-
-
Jules, J.1
Maiguel, D.2
Hudson, B.I.3
-
41
-
-
58149101483
-
Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases
-
Zhang, L.; Bukulin, M.; Kojro, E.; Roth, A.; Metz, V. V.; Fahrenholz, F.; Nawroth, P. P.; Bierhaus, A.; Postina, R. Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases J. Biol. Chem. 2008, 283, 35507-35516 10.1074/jbc.M806948200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 35507-35516
-
-
Zhang, L.1
Bukulin, M.2
Kojro, E.3
Roth, A.4
Metz, V.V.5
Fahrenholz, F.6
Nawroth, P.P.7
Bierhaus, A.8
Postina, R.9
-
42
-
-
84896291628
-
The relationship between RAGE gene four common polymorphisms and breast cancer risk in northeastern Han Chinese
-
Pan, H.; He, L.; Wang, B.; Niu, W. The relationship between RAGE gene four common polymorphisms and breast cancer risk in northeastern Han Chinese Sci. Rep. 2015, 4, 4355 10.1038/srep04355
-
(2015)
Sci. Rep.
, vol.4
, pp. 4355
-
-
Pan, H.1
He, L.2
Wang, B.3
Niu, W.4
-
43
-
-
84950135003
-
Association of 2184AG Polymorphism in the RAGE Gene with Diabetic Nephropathy in Chinese Patients with Type 2 Diabetes
-
Cai, W.; Li, J.; Xu, J. X.; Liu, Y.; Zhang, W.; Xiao, J. R.; Zhu, L. Y.; Liu, J. Y. Association of 2184AG Polymorphism in the RAGE Gene with Diabetic Nephropathy in Chinese Patients with Type 2 Diabetes J. Diabetes Res. 2015, 2015, 310237 10.1155/2015/310237
-
(2015)
J. Diabetes Res.
, vol.2015
, pp. 310237
-
-
Cai, W.1
Li, J.2
Xu, J.X.3
Liu, Y.4
Zhang, W.5
Xiao, J.R.6
Zhu, L.Y.7
Liu, J.Y.8
-
44
-
-
43249092154
-
Identification, classification, and expression of RAGE gene splice variants
-
Hudson, B. I.; Carter, A. M.; Harja, E.; Kalea, A. Z.; Arriero, M.; Yang, H.; Grant, P. J.; Schmidt, A. M. Identification, classification, and expression of RAGE gene splice variants FASEB J. 2008, 22, 1572-1580 10.1096/fj.07-9909com
-
(2008)
FASEB J.
, vol.22
, pp. 1572-1580
-
-
Hudson, B.I.1
Carter, A.M.2
Harja, E.3
Kalea, A.Z.4
Arriero, M.5
Yang, H.6
Grant, P.J.7
Schmidt, A.M.8
-
45
-
-
26944494920
-
Evaluation of rage isoforms, ligands, and signaling in the brain
-
Ding, Q.; Keller, J. N. Evaluation of rage isoforms, ligands, and signaling in the brain Biochim. Biophys. Acta, Mol. Cell Res. 2005, 1746, 18-27 10.1016/j.bbamcr.2005.08.006
-
(2005)
Biochim. Biophys. Acta, Mol. Cell Res.
, vol.1746
, pp. 18-27
-
-
Ding, Q.1
Keller, J.N.2
-
46
-
-
84953287235
-
Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-beta Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus
-
Hong, Y.; Shen, C.; Yin, Q.; Sun, M.; Ma, Y.; Liu, X. Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-beta Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus Neurochem. Res. 2016, 41, 1192-1199 10.1007/s11064-015-1814-8
-
(2016)
Neurochem. Res.
, vol.41
, pp. 1192-1199
-
-
Hong, Y.1
Shen, C.2
Yin, Q.3
Sun, M.4
Ma, Y.5
Liu, X.6
-
47
-
-
33847765812
-
Inhibition of diabetic leukostasis and blood-retinal barrier breakdown with a soluble form of a receptor for advanced glycation end products
-
Kaji, Y.; Usui, T.; Ishida, S.; Yamashiro, K.; Moore, T. C.; Moore, J.; Yamamoto, Y.; Yamamoto, H.; Adamis, A. P. Inhibition of diabetic leukostasis and blood-retinal barrier breakdown with a soluble form of a receptor for advanced glycation end products Invest. Ophthalmol. Visual Sci. 2007, 48, 858-865 10.1167/iovs.06-0495
-
(2007)
Invest. Ophthalmol. Visual Sci.
, vol.48
, pp. 858-865
-
-
Kaji, Y.1
Usui, T.2
Ishida, S.3
Yamashiro, K.4
Moore, T.C.5
Moore, J.6
Yamamoto, Y.7
Yamamoto, H.8
Adamis, A.P.9
-
48
-
-
84878177195
-
Low molecular weight heparin suppresses receptor for advanced glycation end products-mediated expression of malignant phenotype in human fibrosarcoma cells
-
Takeuchi, A.; Yamamoto, Y.; Munesue, S.; Harashima, A.; Watanabe, T.; Yonekura, H.; Yamamoto, H.; Tsuchiya, H. Low molecular weight heparin suppresses receptor for advanced glycation end products-mediated expression of malignant phenotype in human fibrosarcoma cells Cancer Sci. 2013, 104, 740-749 10.1111/cas.12133
-
(2013)
Cancer Sci.
, vol.104
, pp. 740-749
-
-
Takeuchi, A.1
Yamamoto, Y.2
Munesue, S.3
Harashima, A.4
Watanabe, T.5
Yonekura, H.6
Yamamoto, H.7
Tsuchiya, H.8
-
49
-
-
84943645501
-
RAGE/NF-kappaB signaling mediates lipopolysaccharide induced acute lung injury in neonate rat model
-
Li, Y.; Wu, R.; Tian, Y.; Yu, M.; Tang, Y.; Cheng, H.; Tian, Z. RAGE/NF-kappaB signaling mediates lipopolysaccharide induced acute lung injury in neonate rat model Int. J. Clin. Exp. Med. 2015, 8, 13371-13376
-
(2015)
Int. J. Clin. Exp. Med.
, vol.8
, pp. 13371-13376
-
-
Li, Y.1
Wu, R.2
Tian, Y.3
Yu, M.4
Tang, Y.5
Cheng, H.6
Tian, Z.7
-
50
-
-
0034840664
-
Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: Identification of a cellular activation mechanism
-
Lue, L. F.; Walker, D. G.; Brachova, L.; Beach, T. G.; Rogers, J.; Schmidt, A. M.; Stern, D. M.; Yan, S. D. Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: Identification of a cellular activation mechanism Exp. Neurol. 2001, 171, 29-45 10.1006/exnr.2001.7732
-
(2001)
Exp. Neurol.
, vol.171
, pp. 29-45
-
-
Lue, L.F.1
Walker, D.G.2
Brachova, L.3
Beach, T.G.4
Rogers, J.5
Schmidt, A.M.6
Stern, D.M.7
Yan, S.D.8
-
51
-
-
0035096603
-
Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells
-
Huang, J. S.; Guh, J. Y.; Chen, H. C.; Hung, W. C.; Lai, Y. H.; Chuang, L. Y. Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells J. Cell. Biochem. 2001, 81, 102-113 10.1002/1097-4644(20010401)81:1<102::AID-JCB1027>3.0.CO;2-Y
-
(2001)
J. Cell. Biochem.
, vol.81
, pp. 102-113
-
-
Huang, J.S.1
Guh, J.Y.2
Chen, H.C.3
Hung, W.C.4
Lai, Y.H.5
Chuang, L.Y.6
-
52
-
-
48949119346
-
RAGE: Developmental expression and positive feedback regulation by Egr-1 during cigarette smoke exposure in pulmonary epithelial cells
-
Reynolds, P. R.; Kasteler, S. D.; Cosio, M. G.; Sturrock, A.; Huecksteadt, T.; Hoidal, J. R. RAGE: developmental expression and positive feedback regulation by Egr-1 during cigarette smoke exposure in pulmonary epithelial cells Am. J. Physiol.: Lung Cell. Mol. Physiol. 2008, 294, L1094-1101 10.1152/ajplung.00318.2007
-
(2008)
Am. J. Physiol.: Lung Cell. Mol. Physiol.
, vol.294
, pp. L1094-1101
-
-
Reynolds, P.R.1
Kasteler, S.D.2
Cosio, M.G.3
Sturrock, A.4
Huecksteadt, T.5
Hoidal, J.R.6
-
53
-
-
84907546605
-
RAGE, receptor of advanced glycation endoproducts, negatively regulates chondrocytes differentiation
-
Kosaka, T.; Fukui, R.; Matsui, M.; Kurosaka, Y.; Nishimura, H.; Tanabe, M.; Takakura, Y.; Iwai, K.; Waki, T.; Fujita, T. RAGE, receptor of advanced glycation endoproducts, negatively regulates chondrocytes differentiation PLoS One 2014, 9, e108819 10.1371/journal.pone.0108819
-
(2014)
PLoS One
, vol.9
, pp. e108819
-
-
Kosaka, T.1
Fukui, R.2
Matsui, M.3
Kurosaka, Y.4
Nishimura, H.5
Tanabe, M.6
Takakura, Y.7
Iwai, K.8
Waki, T.9
Fujita, T.10
-
54
-
-
0037444761
-
Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury
-
Yonekura, H.; Yamamoto, Y.; Sakurai, S.; Petrova, R. G.; Abedin, M. J.; Li, H.; Yasui, K.; Takeuchi, M.; Makita, Z.; Takasawa, S.; Okamoto, H.; Watanabe, T.; Yamamoto, H. Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury Biochem. J. 2003, 370, 1097-1109 10.1042/bj20021371
-
(2003)
Biochem. J.
, vol.370
, pp. 1097-1109
-
-
Yonekura, H.1
Yamamoto, Y.2
Sakurai, S.3
Petrova, R.G.4
Abedin, M.J.5
Li, H.6
Yasui, K.7
Takeuchi, M.8
Makita, Z.9
Takasawa, S.10
Okamoto, H.11
Watanabe, T.12
Yamamoto, H.13
-
55
-
-
66949157648
-
RAGE: A novel biological and genetic marker for vascular disease
-
Kalea, A. Z.; Schmidt, A. M.; Hudson, B. I. RAGE: a novel biological and genetic marker for vascular disease Clin. Sci. 2009, 116, 621-637 10.1042/CS20080494
-
(2009)
Clin. Sci.
, vol.116
, pp. 621-637
-
-
Kalea, A.Z.1
Schmidt, A.M.2
Hudson, B.I.3
-
56
-
-
33745741894
-
Soluble receptor for advanced glycation end products: From disease marker to potential therapeutic target
-
Geroldi, D.; Falcone, C.; Emanuele, E. Soluble receptor for advanced glycation end products: from disease marker to potential therapeutic target Curr. Med. Chem. 2006, 13, 1971-1978 10.2174/092986706777585013
-
(2006)
Curr. Med. Chem.
, vol.13
, pp. 1971-1978
-
-
Geroldi, D.1
Falcone, C.2
Emanuele, E.3
-
57
-
-
33747039218
-
Positive association between serum levels of advanced glycation end products and the soluble form of receptor for advanced glycation end products in nondiabetic subjects
-
Yamagishi, S.; Adachi, H.; Nakamura, K.; Matsui, T.; Jinnouchi, Y.; Takenaka, K.; Takeuchi, M.; Enomoto, M.; Furuki, K.; Hino, A.; Shigeto, Y.; Imaizumi, T. Positive association between serum levels of advanced glycation end products and the soluble form of receptor for advanced glycation end products in nondiabetic subjects Metab., Clin. Exp. 2006, 55, 1227-1231 10.1016/j.metabol.2006.05.007
-
(2006)
Metab., Clin. Exp.
, vol.55
, pp. 1227-1231
-
-
Yamagishi, S.1
Adachi, H.2
Nakamura, K.3
Matsui, T.4
Jinnouchi, Y.5
Takenaka, K.6
Takeuchi, M.7
Enomoto, M.8
Furuki, K.9
Hino, A.10
Shigeto, Y.11
Imaizumi, T.12
-
58
-
-
68849129707
-
RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model
-
Cho, H. J.; Son, S. M.; Jin, S. M.; Hong, H. S.; Shin, D. H.; Kim, S. J.; Huh, K.; Mook-Jung, I. RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model FASEB J. 2009, 23, 2639-2649 10.1096/fj.08-126383
-
(2009)
FASEB J.
, vol.23
, pp. 2639-2649
-
-
Cho, H.J.1
Son, S.M.2
Jin, S.M.3
Hong, H.S.4
Shin, D.H.5
Kim, S.J.6
Huh, K.7
Mook-Jung, I.8
-
59
-
-
65649127808
-
Soluble forms of RAGE in human diseases: Clinical and therapeutical implications
-
Santilli, F.; Vazzana, N.; Bucciarelli, L. G.; Davi, G. Soluble forms of RAGE in human diseases: clinical and therapeutical implications Curr. Med. Chem. 2009, 16, 940-952 10.2174/092986709787581888
-
(2009)
Curr. Med. Chem.
, vol.16
, pp. 940-952
-
-
Santilli, F.1
Vazzana, N.2
Bucciarelli, L.G.3
Davi, G.4
-
60
-
-
70849087805
-
Ectodomain shedding of the receptor for advanced glycation end products: A novel therapeutic target for Alzheimer's disease
-
Zhang, L.; Postina, R.; Wang, Y. Ectodomain shedding of the receptor for advanced glycation end products: a novel therapeutic target for Alzheimer's disease Cell. Mol. Life Sci. 2009, 66, 3923-3935 10.1007/s00018-009-0121-4
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 3923-3935
-
-
Zhang, L.1
Postina, R.2
Wang, Y.3
-
61
-
-
78650341420
-
The 1.5 A crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding
-
Park, H.; Boyington, J. C. The 1.5 A crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding J. Biol. Chem. 2010, 285, 40762-40770 10.1074/jbc.M110.169276
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 40762-40770
-
-
Park, H.1
Boyington, J.C.2
-
62
-
-
34548070752
-
Structural and functional insights into RAGE activation by multimeric S100B
-
Ostendorp, T.; Leclerc, E.; Galichet, A.; Koch, M.; Demling, N.; Weigle, B.; Heizmann, C. W.; Kroneck, P. M.; Fritz, G. Structural and functional insights into RAGE activation by multimeric S100B EMBO J. 2007, 26, 3868-3878 10.1038/sj.emboj.7601805
-
(2007)
EMBO J.
, vol.26
, pp. 3868-3878
-
-
Ostendorp, T.1
Leclerc, E.2
Galichet, A.3
Koch, M.4
Demling, N.5
Weigle, B.6
Heizmann, C.W.7
Kroneck, P.M.8
Fritz, G.9
-
63
-
-
0037102393
-
Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis
-
Huttunen, H. J.; Fages, C.; Kuja-Panula, J.; Ridley, A. J.; Rauvala, H. Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis Cancer Res. 2002, 62, 4805-4811
-
(2002)
Cancer Res.
, vol.62
, pp. 4805-4811
-
-
Huttunen, H.J.1
Fages, C.2
Kuja-Panula, J.3
Ridley, A.J.4
Rauvala, H.5
-
64
-
-
79953890803
-
The Structural Biology of Toll-like Receptors
-
Botos, I.; Segal, D. M.; Davies, D. R. The Structural Biology of Toll-like Receptors Structure 2011, 19, 447-459 10.1016/j.str.2011.02.004
-
(2011)
Structure
, vol.19
, pp. 447-459
-
-
Botos, I.1
Segal, D.M.2
Davies, D.R.3
-
65
-
-
53349125963
-
Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells
-
Sinha, P.; Okoro, C.; Foell, D.; Freeze, H. H.; Ostrand-Rosenberg, S.; Srikrishna, G. Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells J. Immunol. 2008, 181, 4666-4675 10.4049/jimmunol.181.7.4666
-
(2008)
J. Immunol.
, vol.181
, pp. 4666-4675
-
-
Sinha, P.1
Okoro, C.2
Foell, D.3
Freeze, H.H.4
Ostrand-Rosenberg, S.5
Srikrishna, G.6
-
66
-
-
0242335599
-
S100B in brain damage and neurodegeneration
-
Rothermundt, M.; Peters, M.; Prehn, J. H.; Arolt, V. S100B in brain damage and neurodegeneration Microsc. Res. Tech. 2003, 60, 614-632 10.1002/jemt.10303
-
(2003)
Microsc. Res. Tech.
, vol.60
, pp. 614-632
-
-
Rothermundt, M.1
Peters, M.2
Prehn, J.H.3
Arolt, V.4
-
67
-
-
17144400438
-
Angiogenetic signaling through hypoxia: HMGB1: An angiogenetic switch molecule
-
Schlueter, C.; Weber, H.; Meyer, B.; Rogalla, P.; Roser, K.; Hauke, S.; Bullerdiek, J. Angiogenetic signaling through hypoxia: HMGB1: an angiogenetic switch molecule Am. J. Pathol. 2005, 166, 1259-1263 10.1016/S0002-9440(10)62344-9
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 1259-1263
-
-
Schlueter, C.1
Weber, H.2
Meyer, B.3
Rogalla, P.4
Roser, K.5
Hauke, S.6
Bullerdiek, J.7
-
68
-
-
84862653321
-
Expression of HMGB1 and RAGE in rat and human brains after traumatic brain injury
-
Gao, T. L.; Yuan, X. T.; Yang, D.; Dai, H. L.; Wang, W. J.; Peng, X.; Shao, H. J.; Jin, Z. F.; Fu, Z. J. Expression of HMGB1 and RAGE in rat and human brains after traumatic brain injury J. Trauma Acute Care Surg. 2012, 72, 643-649 10.1097/TA.0b013e31823c54a6
-
(2012)
J. Trauma Acute Care Surg.
, vol.72
, pp. 643-649
-
-
Gao, T.L.1
Yuan, X.T.2
Yang, D.3
Dai, H.L.4
Wang, W.J.5
Peng, X.6
Shao, H.J.7
Jin, Z.F.8
Fu, Z.J.9
-
69
-
-
84864295014
-
Dietary intake increases serum levels of carboxymethil-lysine (CML) in diabetic patients
-
Jara, N.; Leal, M. J.; Bunout, D.; Hirsch, S.; Barrera, G.; Leiva, L.; de la Maza, M. P. Dietary intake increases serum levels of carboxymethil-lysine (CML) in diabetic patients Nutr. Hosp. 2012, 27, 1272-1278 10.3305/nh.2012.27.4.5861
-
(2012)
Nutr. Hosp.
, vol.27
, pp. 1272-1278
-
-
Jara, N.1
Leal, M.J.2
Bunout, D.3
Hirsch, S.4
Barrera, G.5
Leiva, L.6
De La Maza, M.P.7
-
70
-
-
21744448064
-
Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds
-
Berlanga, J.; Cibrian, D.; Guillen, I.; Freyre, F.; Alba, J. S.; Lopez-Saura, P.; Merino, N.; Aldama, A.; Quintela, A. M.; Triana, M. E.; Montequin, J. F.; Ajamieh, H.; Urquiza, D.; Ahmed, N.; Thornalley, P. J. Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds Clin. Sci. 2005, 109, 83-95 10.1042/CS20050026
-
(2005)
Clin. Sci.
, vol.109
, pp. 83-95
-
-
Berlanga, J.1
Cibrian, D.2
Guillen, I.3
Freyre, F.4
Alba, J.S.5
Lopez-Saura, P.6
Merino, N.7
Aldama, A.8
Quintela, A.M.9
Triana, M.E.10
Montequin, J.F.11
Ajamieh, H.12
Urquiza, D.13
Ahmed, N.14
Thornalley, P.J.15
-
71
-
-
67349265963
-
Binding of S100 proteins to RAGE: An update
-
Leclerc, E.; Fritz, G.; Vetter, S. W.; Heizmann, C. W. Binding of S100 proteins to RAGE: an update Biochim. Biophys. Acta, Mol. Cell Res. 2009, 1793, 993-1007 10.1016/j.bbamcr.2008.11.016
-
(2009)
Biochim. Biophys. Acta, Mol. Cell Res.
, vol.1793
, pp. 993-1007
-
-
Leclerc, E.1
Fritz, G.2
Vetter, S.W.3
Heizmann, C.W.4
-
72
-
-
35748967902
-
S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains
-
Leclerc, E.; Fritz, G.; Weibel, M.; Heizmann, C. W.; Galichet, A. S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains J. Biol. Chem. 2007, 282, 31317-31331 10.1074/jbc.M703951200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 31317-31331
-
-
Leclerc, E.1
Fritz, G.2
Weibel, M.3
Heizmann, C.W.4
Galichet, A.5
-
73
-
-
84879880601
-
S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer
-
Onyeagucha, B. C.; Mercado-Pimentel, M. E.; Hutchison, J.; Flemington, E. K.; Nelson, M. A. S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer Exp. Cell Res. 2013, 319, 2081-2090 10.1016/j.yexcr.2013.05.009
-
(2013)
Exp. Cell Res.
, vol.319
, pp. 2081-2090
-
-
Onyeagucha, B.C.1
Mercado-Pimentel, M.E.2
Hutchison, J.3
Flemington, E.K.4
Nelson, M.A.5
-
74
-
-
0033603241
-
RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
-
Hofmann, M. A.; Drury, S.; Fu, C.; Qu, W.; Taguchi, A.; Lu, Y.; Avila, C.; Kambham, N.; Bierhaus, A.; Nawroth, P.; Neurath, M. F.; Slattery, T.; Beach, D.; McClary, J.; Nagashima, M.; Morser, J.; Stern, D.; Schmidt, A. M. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides Cell 1999, 97, 889-901 10.1016/S0092-8674(00)80801-6
-
(1999)
Cell
, vol.97
, pp. 889-901
-
-
Hofmann, M.A.1
Drury, S.2
Fu, C.3
Qu, W.4
Taguchi, A.5
Lu, Y.6
Avila, C.7
Kambham, N.8
Bierhaus, A.9
Nawroth, P.10
Neurath, M.F.11
Slattery, T.12
Beach, D.13
McClary, J.14
Nagashima, M.15
Morser, J.16
Stern, D.17
Schmidt, A.M.18
-
75
-
-
84981710200
-
Change in the Molecular Dimension of a RAGE-Ligand Complex Triggers RAGE Signaling
-
Xue, J.; Manigrasso, M.; Scalabrin, M.; Rai, V.; Reverdatto, S.; Burz, D. S.; Fabris, D.; Schmidt, A. M.; Shekhtman, A. Change in the Molecular Dimension of a RAGE-Ligand Complex Triggers RAGE Signaling Structure 2016, 24, 1509-1522 10.1016/j.str.2016.06.021
-
(2016)
Structure
, vol.24
, pp. 1509-1522
-
-
Xue, J.1
Manigrasso, M.2
Scalabrin, M.3
Rai, V.4
Reverdatto, S.5
Burz, D.S.6
Fabris, D.7
Schmidt, A.M.8
Shekhtman, A.9
-
76
-
-
84938846647
-
The S100P/RAGE signaling pathway regulates expression of microRNA-21 in colon cancer cells
-
Mercado-Pimentel, M. E.; Onyeagucha, B. C.; Li, Q.; Pimentel, A. C.; Jandova, J.; Nelson, M. A. The S100P/RAGE signaling pathway regulates expression of microRNA-21 in colon cancer cells FEBS Lett. 2015, 589, 2388-2393 10.1016/j.febslet.2015.07.010
-
(2015)
FEBS Lett.
, vol.589
, pp. 2388-2393
-
-
Mercado-Pimentel, M.E.1
Onyeagucha, B.C.2
Li, Q.3
Pimentel, A.C.4
Jandova, J.5
Nelson, M.A.6
-
77
-
-
84905498385
-
Structural insights into calcium-bound S100P and the v domain of the RAGE complex
-
Penumutchu, S. R.; Chou, R. H.; Yu, C. Structural insights into calcium-bound S100P and the V domain of the RAGE complex PLoS One 2014, 9, e103947 10.1371/journal.pone.0103947
-
(2014)
PLoS One
, vol.9
, pp. e103947
-
-
Penumutchu, S.R.1
Chou, R.H.2
Yu, C.3
-
78
-
-
1242272130
-
S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE)
-
Arumugam, T.; Simeone, D. M.; Schmidt, A. M.; Logsdon, C. D. S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE) J. Biol. Chem. 2004, 279, 5059-5065 10.1074/jbc.M310124200
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5059-5065
-
-
Arumugam, T.1
Simeone, D.M.2
Schmidt, A.M.3
Logsdon, C.D.4
-
79
-
-
56749146313
-
Solution structure of the variable-type domain of the receptor for advanced glycation end products: New insight into AGE-RAGE interaction
-
Matsumoto, S.; Yoshida, T.; Murata, H.; Harada, S.; Fujita, N.; Nakamura, S.; Yamamoto, Y.; Watanabe, T.; Yonekura, H.; Yamamoto, H.; Ohkubo, T.; Kobayashi, Y. Solution structure of the variable-type domain of the receptor for advanced glycation end products: new insight into AGE-RAGE interaction Biochemistry 2008, 47, 12299-12311 10.1021/bi800910v
-
(2008)
Biochemistry
, vol.47
, pp. 12299-12311
-
-
Matsumoto, S.1
Yoshida, T.2
Murata, H.3
Harada, S.4
Fujita, N.5
Nakamura, S.6
Yamamoto, Y.7
Watanabe, T.8
Yonekura, H.9
Yamamoto, H.10
Ohkubo, T.11
Kobayashi, Y.12
-
80
-
-
84878180533
-
Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14
-
Kim, S.; Kim, S. Y.; Pribis, J. P.; Lotze, M.; Mollen, K. P.; Shapiro, R.; Loughran, P.; Scott, M. J.; Billiar, T. R. Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14 Mol. Med. 2013, 19, 88-98 10.2119/molmed.2012.00306
-
(2013)
Mol. Med.
, vol.19
, pp. 88-98
-
-
Kim, S.1
Kim, S.Y.2
Pribis, J.P.3
Lotze, M.4
Mollen, K.P.5
Shapiro, R.6
Loughran, P.7
Scott, M.J.8
Billiar, T.R.9
-
81
-
-
33847193122
-
A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin
-
Orlova, V. V.; Choi, E. Y.; Xie, C.; Chavakis, E.; Bierhaus, A.; Ihanus, E.; Ballantyne, C. M.; Gahmberg, C. G.; Bianchi, M. E.; Nawroth, P. P.; Chavakis, T. A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin EMBO J. 2007, 26, 1129-1139 10.1038/sj.emboj.7601552
-
(2007)
EMBO J.
, vol.26
, pp. 1129-1139
-
-
Orlova, V.V.1
Choi, E.Y.2
Xie, C.3
Chavakis, E.4
Bierhaus, A.5
Ihanus, E.6
Ballantyne, C.M.7
Gahmberg, C.G.8
Bianchi, M.E.9
Nawroth, P.P.10
Chavakis, T.11
-
82
-
-
0013615899
-
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
-
Yan, S. D.; Chen, X.; Fu, J.; Chen, M.; Zhu, H.; Roher, A.; Slattery, T.; Zhao, L.; Nagashima, M.; Morser, J.; Migheli, A.; Nawroth, P.; Stern, D.; Schmidt, A. M. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease Nature 1996, 382, 685-691 10.1038/382685a0
-
(1996)
Nature
, vol.382
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zhu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
83
-
-
20444462454
-
RAGE and amyloid beta interactions: Atomic force microscopy and molecular modeling
-
Chaney, M. O.; Stine, W. B.; Kokjohn, T. A.; Kuo, Y. M.; Esh, C.; Rahman, A.; Luehrs, D. C.; Schmidt, A. M.; Stern, D.; Yan, S. D.; Roher, A. E. RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling Biochim. Biophys. Acta, Mol. Basis Dis. 2005, 1741, 199-205 10.1016/j.bbadis.2005.03.014
-
(2005)
Biochim. Biophys. Acta, Mol. Basis Dis.
, vol.1741
, pp. 199-205
-
-
Chaney, M.O.1
Stine, W.B.2
Kokjohn, T.A.3
Kuo, Y.M.4
Esh, C.5
Rahman, A.6
Luehrs, D.C.7
Schmidt, A.M.8
Stern, D.9
Yan, S.D.10
Roher, A.E.11
-
84
-
-
0037703255
-
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain
-
Deane, R.; Du Yan, S.; Submamaryan, R. K.; LaRue, B.; Jovanovic, S.; Hogg, E.; Welch, D.; Manness, L.; Lin, C.; Yu, J.; Zhu, H.; Ghiso, J.; Frangione, B.; Stern, A.; Schmidt, A. M.; Armstrong, D. L.; Arnold, B.; Liliensiek, B.; Nawroth, P.; Hofman, F.; Kindy, M.; Stern, D.; Zlokovic, B. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain Nat. Med. 2003, 9, 907-913 10.1038/nm890
-
(2003)
Nat. Med.
, vol.9
, pp. 907-913
-
-
Deane, R.1
Du Yan, S.2
Submamaryan, R.K.3
LaRue, B.4
Jovanovic, S.5
Hogg, E.6
Welch, D.7
Manness, L.8
Lin, C.9
Yu, J.10
Zhu, H.11
Ghiso, J.12
Frangione, B.13
Stern, A.14
Schmidt, A.M.15
Armstrong, D.L.16
Arnold, B.17
Liliensiek, B.18
Nawroth, P.19
Hofman, F.20
Kindy, M.21
Stern, D.22
Zlokovic, B.23
more..
-
85
-
-
0031821610
-
RAGE-Abeta interactions in the pathophysiology of Alzheimer's disease
-
Yan, S. D.; Stern, D.; Kane, M. D.; Kuo, Y. M.; Lampert, H. C.; Roher, A. E. RAGE-Abeta interactions in the pathophysiology of Alzheimer's disease Restor. Neurol. Neurosci. 1998, 12, 167-173
-
(1998)
Restor. Neurol. Neurosci.
, vol.12
, pp. 167-173
-
-
Yan, S.D.1
Stern, D.2
Kane, M.D.3
Kuo, Y.M.4
Lampert, H.C.5
Roher, A.E.6
-
86
-
-
84884856782
-
Quinolinic acid: An endogenous neurotoxin with multiple targets
-
Lugo-Huitron, R.; Ugalde Muniz, P.; Pineda, B.; Pedraza-Chaverri, J.; Rios, C.; Perez-de la Cruz, V. Quinolinic acid: an endogenous neurotoxin with multiple targets Oxid. Med. Cell. Longevity 2013, 2013, 104024 10.1155/2013/104024
-
(2013)
Oxid. Med. Cell. Longevity
, vol.2013
, pp. 104024
-
-
Lugo-Huitron, R.1
Ugalde Muniz, P.2
Pineda, B.3
Pedraza-Chaverri, J.4
Rios, C.5
Perez-De La Cruz, V.6
-
87
-
-
84924371085
-
Modeling the Interaction between Quinolinate and the Receptor for Advanced Glycation End Products (RAGE): Relevance for Early Neuropathological Processes
-
Serratos, I. N.; Castellanos, P.; Pastor, N.; Millán-Pacheco, C.; Rembao, D.; Pérez-Montfort, R.; Cabrera, N.; Reyes-Espinosa, F.; Díaz-Garrido, P.; López-Macay, A.; Martínez-Flores, K.; López-Reyes, A.; Sánchez-García, A.; Cuevas, E.; Santamaria, A. Modeling the Interaction between Quinolinate and the Receptor for Advanced Glycation End Products (RAGE): Relevance for Early Neuropathological Processes PLoS One 2015, 10, e0120221 10.1371/journal.pone.0120221
-
(2015)
PLoS One
, vol.10
, pp. e0120221
-
-
Serratos, I.N.1
Castellanos, P.2
Pastor, N.3
Millán-Pacheco, C.4
Rembao, D.5
Pérez-Montfort, R.6
Cabrera, N.7
Reyes-Espinosa, F.8
Díaz-Garrido, P.9
López-Macay, A.10
Martínez-Flores, K.11
López-Reyes, A.12
Sánchez-García, A.13
Cuevas, E.14
Santamaria, A.15
-
88
-
-
77951258749
-
On the early toxic effect of quinolinic acid: Involvement of RAGE
-
Cuevas, E.; Lantz, S.; Newport, G.; Divine, B.; Wu, Q.; Paule, M. G.; Tobon-Velasco, J. C.; Ali, S. F.; Santamaria, A. On the early toxic effect of quinolinic acid: involvement of RAGE Neurosci. Lett. 2010, 474, 74-78 10.1016/j.neulet.2010.03.007
-
(2010)
Neurosci. Lett.
, vol.474
, pp. 74-78
-
-
Cuevas, E.1
Lantz, S.2
Newport, G.3
Divine, B.4
Wu, Q.5
Paule, M.G.6
Tobon-Velasco, J.C.7
Ali, S.F.8
Santamaria, A.9
-
89
-
-
84872768774
-
DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells
-
Yamamoto, K.; Murata, H.; Putranto, E. W.; Kataoka, K.; Motoyama, A.; Hibino, T.; Inoue, Y.; Sakaguchi, M.; Huh, N. H. DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells Oncol. Rep. 2013, 29, 1073-1079 10.3892/or.2012.2191
-
(2013)
Oncol. Rep.
, vol.29
, pp. 1073-1079
-
-
Yamamoto, K.1
Murata, H.2
Putranto, E.W.3
Kataoka, K.4
Motoyama, A.5
Hibino, T.6
Inoue, Y.7
Sakaguchi, M.8
Huh, N.H.9
-
90
-
-
84938803540
-
Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion
-
Lin, Y. N.; Bhuwania, R.; Gromova, K.; Failla, A. V.; Lange, T.; Riecken, K.; Linder, S.; Kneussel, M.; Izbicki, J. R.; Windhorst, S. Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion Oncotarget 2015, 6, 18577-18589 10.18632/oncotarget.4094
-
(2015)
Oncotarget
, vol.6
, pp. 18577-18589
-
-
Lin, Y.N.1
Bhuwania, R.2
Gromova, K.3
Failla, A.V.4
Lange, T.5
Riecken, K.6
Linder, S.7
Kneussel, M.8
Izbicki, J.R.9
Windhorst, S.10
-
91
-
-
73849113154
-
Advanced glycation end-products activate extracellular signal-regulated kinase via the oxidative stress-EGF receptor pathway in renal fibroblasts
-
Chen, S. C.; Guh, J. Y.; Hwang, C. C.; Chiou, S. J.; Lin, T. D.; Ko, Y. M.; Huang, J. S.; Yang, Y. L.; Chuang, L. Y. Advanced glycation end-products activate extracellular signal-regulated kinase via the oxidative stress-EGF receptor pathway in renal fibroblasts J. Cell. Biochem. 2010, 109, 38-48 10.1002/jcb.22376
-
(2010)
J. Cell. Biochem.
, vol.109
, pp. 38-48
-
-
Chen, S.C.1
Guh, J.Y.2
Hwang, C.C.3
Chiou, S.J.4
Lin, T.D.5
Ko, Y.M.6
Huang, J.S.7
Yang, Y.L.8
Chuang, L.Y.9
-
92
-
-
84879522773
-
Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7
-
Zhou, Y.; Johnson, J. L.; Cerione, R. A.; Erickson, J. W. Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7 Biochemistry 2013, 52, 4354-4363 10.1021/bi301688g
-
(2013)
Biochemistry
, vol.52
, pp. 4354-4363
-
-
Zhou, Y.1
Johnson, J.L.2
Cerione, R.A.3
Erickson, J.W.4
-
93
-
-
0027718105
-
Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues
-
Brett, J.; Schmidt, A. M.; Yan, S. D.; Zou, Y. S.; Weidman, E.; Pinsky, D.; Nowygrod, R.; Neeper, M.; Przysiecki, C.; Shaw, A. et al. Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues Am. J. Pathol. 1993, 143, 1699-1712
-
(1993)
Am. J. Pathol.
, vol.143
, pp. 1699-1712
-
-
Brett, J.1
Schmidt, A.M.2
Yan, S.D.3
Zou, Y.S.4
Weidman, E.5
Pinsky, D.6
Nowygrod, R.7
Neeper, M.8
Przysiecki, C.9
Shaw, A.10
-
94
-
-
30944454884
-
RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes
-
Wendt, T.; Harja, E.; Bucciarelli, L.; Qu, W.; Lu, Y.; Rong, L. L.; Jenkins, D. G.; Stein, G.; Schmidt, A. M.; Yan, S. F. RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes Atherosclerosis 2006, 185, 70-77 10.1016/j.atherosclerosis.2005.06.013
-
(2006)
Atherosclerosis
, vol.185
, pp. 70-77
-
-
Wendt, T.1
Harja, E.2
Bucciarelli, L.3
Qu, W.4
Lu, Y.5
Rong, L.L.6
Jenkins, D.G.7
Stein, G.8
Schmidt, A.M.9
Yan, S.F.10
-
95
-
-
11144324314
-
Advanced glycation endproducts - Role in pathology of diabetic complications
-
Ahmed, N. Advanced glycation endproducts - role in pathology of diabetic complications Diabetes Res. Clin. Pract. 2005, 67, 3-21 10.1016/j.diabres.2004.09.004
-
(2005)
Diabetes Res. Clin. Pract.
, vol.67
, pp. 3-21
-
-
Ahmed, N.1
-
96
-
-
33646243227
-
Receptor for advanced glycation end-products is a marker of type i cell injury in acute lung injury
-
Uchida, T.; Shirasawa, M.; Ware, L. B.; Kojima, K.; Hata, Y.; Makita, K.; Mednick, G.; Matthay, Z. A.; Matthay, M. A. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury Am. J. Respir. Crit. Care Med. 2006, 173, 1008-1015 10.1164/rccm.200509-1477OC
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.173
, pp. 1008-1015
-
-
Uchida, T.1
Shirasawa, M.2
Ware, L.B.3
Kojima, K.4
Hata, Y.5
Makita, K.6
Mednick, G.7
Matthay, Z.A.8
Matthay, M.A.9
-
97
-
-
77951922772
-
The receptor for advanced glycation end products (RAGE) and the lung
-
Buckley, S. T.; Ehrhardt, C. The receptor for advanced glycation end products (RAGE) and the lung J. Biomed. Biotechnol. 2010, 2010, 917108 10.1155/2010/917108
-
(2010)
J. Biomed. Biotechnol.
, vol.2010
, pp. 917108
-
-
Buckley, S.T.1
Ehrhardt, C.2
-
98
-
-
85029532902
-
RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-KB
-
Zeng, S.; Cataldegirmen, G.; Feirt, N.; Ippagunta, N.; Dun, H.; Wu, Q.; Yan, L.; Rong, L. L.; Yan, S. F.; Schmidt, A. M.; Emond, J. C. RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-KB Hepatology 2004, 40, 284a-285a
-
(2004)
Hepatology
, vol.40
, pp. 284a-285a
-
-
Zeng, S.1
Cataldegirmen, G.2
Feirt, N.3
Ippagunta, N.4
Dun, H.5
Wu, Q.6
Yan, L.7
Rong, L.L.8
Yan, S.F.9
Schmidt, A.M.10
Emond, J.C.11
-
99
-
-
73449133329
-
AGEs increased migration and inflammatory responses of adventitial fibroblasts via RAGE, MAPK and NF-kappaB pathways
-
Liu, Y.; Liang, C.; Liu, X.; Liao, B.; Pan, X.; Ren, Y.; Fan, M.; Li, M.; He, Z.; Wu, J.; Wu, Z. AGEs increased migration and inflammatory responses of adventitial fibroblasts via RAGE, MAPK and NF-kappaB pathways Atherosclerosis 2010, 208, 34-42 10.1016/j.atherosclerosis.2009.06.007
-
(2010)
Atherosclerosis
, vol.208
, pp. 34-42
-
-
Liu, Y.1
Liang, C.2
Liu, X.3
Liao, B.4
Pan, X.5
Ren, Y.6
Fan, M.7
Li, M.8
He, Z.9
Wu, J.10
Wu, Z.11
-
100
-
-
0034987093
-
Requirement for p38 and p44/p42 mitogen-activated protein kinases in RAGE-mediated nuclear factor-kappaB transcriptional activation and cytokine secretion
-
Yeh, C. H.; Sturgis, L.; Haidacher, J.; Zhang, X. N.; Sherwood, S. J.; Bjercke, R. J.; Juhasz, O.; Crow, M. T.; Tilton, R. G.; Denner, L. Requirement for p38 and p44/p42 mitogen-activated protein kinases in RAGE-mediated nuclear factor-kappaB transcriptional activation and cytokine secretion Diabetes 2001, 50, 1495-1504 10.2337/diabetes.50.6.1495
-
(2001)
Diabetes
, vol.50
, pp. 1495-1504
-
-
Yeh, C.H.1
Sturgis, L.2
Haidacher, J.3
Zhang, X.N.4
Sherwood, S.J.5
Bjercke, R.J.6
Juhasz, O.7
Crow, M.T.8
Tilton, R.G.9
Denner, L.10
-
101
-
-
33845768987
-
Integrating cell-signalling pathways with NF-kappaB and IKK function
-
Perkins, N. D. Integrating cell-signalling pathways with NF-kappaB and IKK function Nat. Rev. Mol. Cell Biol. 2007, 8, 49-62 10.1038/nrm2083
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 49-62
-
-
Perkins, N.D.1
-
102
-
-
84856428468
-
Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease
-
Chen, C. H.; Zhou, W.; Liu, S.; Deng, Y.; Cai, F.; Tone, M.; Tone, Y.; Tong, Y.; Song, W. Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease Int. J. Neuropsychopharmacol. 2012, 15, 77-90 10.1017/S1461145711000149
-
(2012)
Int. J. Neuropsychopharmacol.
, vol.15
, pp. 77-90
-
-
Chen, C.H.1
Zhou, W.2
Liu, S.3
Deng, Y.4
Cai, F.5
Tone, M.6
Tone, Y.7
Tong, Y.8
Song, W.9
-
103
-
-
77049088494
-
S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 Co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alpha
-
Bianchi, R.; Giambanco, I.; Donato, R. S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 Co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alpha Neurobiol. Aging 2010, 31, 665-677 10.1016/j.neurobiolaging.2008.05.017
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 665-677
-
-
Bianchi, R.1
Giambanco, I.2
Donato, R.3
-
104
-
-
84917706979
-
RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma
-
Chen, X.; Zhang, L.; Zhang, I. Y.; Liang, J.; Wang, H.; Ouyang, M.; Wu, S.; da Fonseca, A. C.; Weng, L.; Yamamoto, Y.; Yamamoto, H.; Natarajan, R.; Badie, B. RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma Cancer Res. 2014, 74, 7285-7297 10.1158/0008-5472.CAN-14-1240
-
(2014)
Cancer Res.
, vol.74
, pp. 7285-7297
-
-
Chen, X.1
Zhang, L.2
Zhang, I.Y.3
Liang, J.4
Wang, H.5
Ouyang, M.6
Wu, S.7
Da Fonseca, A.C.8
Weng, L.9
Yamamoto, Y.10
Yamamoto, H.11
Natarajan, R.12
Badie, B.13
-
105
-
-
34447623162
-
RAGE activation by S100P in colon cancer stimulates growth, migration, and cell signaling pathways
-
Fuentes, M. K.; Nigavekar, S. S.; Arumugam, T.; Logsdon, C. D.; Schmidt, A. M.; Park, J. C.; Huang, E. H. RAGE activation by S100P in colon cancer stimulates growth, migration, and cell signaling pathways Dis. Colon Rectum 2007, 50, 1230-1240 10.1007/s10350-006-0850-5
-
(2007)
Dis. Colon Rectum
, vol.50
, pp. 1230-1240
-
-
Fuentes, M.K.1
Nigavekar, S.S.2
Arumugam, T.3
Logsdon, C.D.4
Schmidt, A.M.5
Park, J.C.6
Huang, E.H.7
-
106
-
-
0035715443
-
Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice
-
Kislinger, T.; Tanji, N.; Wendt, T.; Qu, W.; Lu, Y.; Ferran, L. J., Jr.; Taguchi, A.; Olson, K.; Bucciarelli, L.; Goova, M.; Hofmann, M. A.; Cataldegirmen, G.; D'Agati, V.; Pischetsrieder, M.; Stern, D. M.; Schmidt, A. M. Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice Arterioscler., Thromb., Vasc. Biol. 2001, 21, 905-910 10.1161/01.ATV.21.6.905
-
(2001)
Arterioscler., Thromb., Vasc. Biol.
, vol.21
, pp. 905-910
-
-
Kislinger, T.1
Tanji, N.2
Wendt, T.3
Qu, W.4
Lu, Y.5
Ferran, L.J.6
Taguchi, A.7
Olson, K.8
Bucciarelli, L.9
Goova, M.10
Hofmann, M.A.11
Cataldegirmen, G.12
D'Agati, V.13
Pischetsrieder, M.14
Stern, D.M.15
Schmidt, A.M.16
-
107
-
-
84255163024
-
Receptor for AGE (RAGE): Signaling mechanisms in the pathogenesis of diabetes and its complications
-
Ramasamy, R.; Yan, S. F.; Schmidt, A. M. Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications Ann. N. Y. Acad. Sci. 2011, 1243, 88-102 10.1111/j.1749-6632.2011.06320.x
-
(2011)
Ann. N. Y. Acad. Sci.
, vol.1243
, pp. 88-102
-
-
Ramasamy, R.1
Yan, S.F.2
Schmidt, A.M.3
-
108
-
-
65249153029
-
RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes
-
Coughlan, M. T.; Thorburn, D. R.; Penfold, S. A.; Laskowski, A.; Harcourt, B. E.; Sourris, K. C.; Tan, A. L.; Fukami, K.; Thallas-Bonke, V.; Nawroth, P. P.; Brownlee, M.; Bierhaus, A.; Cooper, M. E.; Forbes, J. M. RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes J. Am. Soc. Nephrol. 2009, 20, 742-752 10.1681/ASN.2008050514
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 742-752
-
-
Coughlan, M.T.1
Thorburn, D.R.2
Penfold, S.A.3
Laskowski, A.4
Harcourt, B.E.5
Sourris, K.C.6
Tan, A.L.7
Fukami, K.8
Thallas-Bonke, V.9
Nawroth, P.P.10
Brownlee, M.11
Bierhaus, A.12
Cooper, M.E.13
Forbes, J.M.14
-
109
-
-
41749084405
-
RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model
-
Aleshin, A.; Ananthakrishnan, R.; Li, Q.; Rosario, R.; Lu, Y.; Qu, W.; Song, F.; Bakr, S.; Szabolcs, M.; D'Agati, V.; Liu, R.; Homma, S.; Schmidt, A. M.; Yan, S. F.; Ramasamy, R. RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model Am. J. Physiol.: Heart Circ. Physiol. 2008, 294, H1823-1832 10.1152/ajpheart.01210.2007
-
(2008)
Am. J. Physiol.: Heart Circ. Physiol.
, vol.294
, pp. H1823-1832
-
-
Aleshin, A.1
Ananthakrishnan, R.2
Li, Q.3
Rosario, R.4
Lu, Y.5
Qu, W.6
Song, F.7
Bakr, S.8
Szabolcs, M.9
D'Agati, V.10
Liu, R.11
Homma, S.12
Schmidt, A.M.13
Yan, S.F.14
Ramasamy, R.15
-
110
-
-
84958156551
-
Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting RAGE Signaling in Diabetic Atherosclerosis
-
Chung, J.; An, S. H.; Kang, S. W.; Kwon, K. Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting RAGE Signaling in Diabetic Atherosclerosis PLoS One 2016, 11, e0147839 10.1371/journal.pone.0147839
-
(2016)
PLoS One
, vol.11
, pp. e0147839
-
-
Chung, J.1
An, S.H.2
Kang, S.W.3
Kwon, K.4
-
111
-
-
0142089894
-
Blockade of receptor for advanced glycation endproducts: A new target for therapeutic intervention in diabetic complications and inflammatory disorders
-
Hudson, B. I.; Bucciarelli, L. G.; Wendt, T.; Sakaguchi, T.; Lalla, E.; Qu, W.; Lu, Y.; Lee, L.; Stern, D. M.; Naka, Y.; Ramasamy, R.; Yan, S. D.; Yan, S. F.; D'Agati, V.; Schmidt, A. M. Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders Arch. Biochem. Biophys. 2003, 419, 80-88 10.1016/j.abb.2003.08.030
-
(2003)
Arch. Biochem. Biophys.
, vol.419
, pp. 80-88
-
-
Hudson, B.I.1
Bucciarelli, L.G.2
Wendt, T.3
Sakaguchi, T.4
Lalla, E.5
Qu, W.6
Lu, Y.7
Lee, L.8
Stern, D.M.9
Naka, Y.10
Ramasamy, R.11
Yan, S.D.12
Yan, S.F.13
D'Agati, V.14
Schmidt, A.M.15
-
112
-
-
84861050637
-
Is RAGE still a therapeutic target for Alzheimer's disease?
-
Deane, R. J. Is RAGE still a therapeutic target for Alzheimer's disease? Future Med. Chem. 2012, 4, 915-925 10.4155/fmc.12.51
-
(2012)
Future Med. Chem.
, vol.4
, pp. 915-925
-
-
Deane, R.J.1
-
113
-
-
54049094343
-
Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease
-
Miller, M. C.; Tavares, R.; Johanson, C. E.; Hovanesian, V.; Donahue, J. E.; Gonzalez, L.; Silverberg, G. D.; Stopa, E. G. Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease Brain Res. 2008, 1230, 273-280 10.1016/j.brainres.2008.06.124
-
(2008)
Brain Res.
, vol.1230
, pp. 273-280
-
-
Miller, M.C.1
Tavares, R.2
Johanson, C.E.3
Hovanesian, V.4
Donahue, J.E.5
Gonzalez, L.6
Silverberg, G.D.7
Stopa, E.G.8
-
114
-
-
0035847269
-
Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease
-
Sasaki, N.; Toki, S.; Chowei, H.; Saito, T.; Nakano, N.; Hayashi, Y.; Takeuchi, M.; Makita, Z. Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease Brain Res. 2001, 888, 256-262 10.1016/S0006-8993(00)03075-4
-
(2001)
Brain Res.
, vol.888
, pp. 256-262
-
-
Sasaki, N.1
Toki, S.2
Chowei, H.3
Saito, T.4
Nakano, N.5
Hayashi, Y.6
Takeuchi, M.7
Makita, Z.8
-
115
-
-
53549086409
-
Evidence for altered LRP/RAGE expression in Alzheimer lesion pathogenesis
-
Jeynes, B.; Provias, J. Evidence for altered LRP/RAGE expression in Alzheimer lesion pathogenesis Curr. Alzheimer Res. 2008, 5, 432-437 10.2174/156720508785908937
-
(2008)
Curr. Alzheimer Res.
, vol.5
, pp. 432-437
-
-
Jeynes, B.1
Provias, J.2
-
116
-
-
33749157416
-
RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease
-
Donahue, J. E.; Flaherty, S. L.; Johanson, C. E.; Duncan, J. A., 3rd; Silverberg, G. D.; Miller, M. C.; Tavares, R.; Yang, W.; Wu, Q.; Sabo, E.; Hovanesian, V.; Stopa, E. G. RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease Acta Neuropathol. 2006, 112, 405-415 10.1007/s00401-006-0115-3
-
(2006)
Acta Neuropathol.
, vol.112
, pp. 405-415
-
-
Donahue, J.E.1
Flaherty, S.L.2
Johanson, C.E.3
Duncan, J.A.4
Silverberg, G.D.5
Miller, M.C.6
Tavares, R.7
Yang, W.8
Wu, Q.9
Sabo, E.10
Hovanesian, V.11
Stopa, E.G.12
-
117
-
-
84861192034
-
AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation
-
Li, X. H.; Lv, B. L.; Xie, J. Z.; Liu, J.; Zhou, X. W.; Wang, J. Z. AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation Neurobiol. Aging 2012, 33, 1400-1410 10.1016/j.neurobiolaging.2011.02.003
-
(2012)
Neurobiol. Aging
, vol.33
, pp. 1400-1410
-
-
Li, X.H.1
Lv, B.L.2
Xie, J.Z.3
Liu, J.4
Zhou, X.W.5
Wang, J.Z.6
-
118
-
-
81355136030
-
AGEs/RAGE complex upregulates BACE1 via NF-kappaB pathway activation
-
196e13327
-
Guglielmotto, M.; Aragno, M.; Tamagno, E.; Vercellinatto, I.; Visentin, S.; Medana, C.; Catalano, M. G.; Smith, M. A.; Perry, G.; Danni, O.; Boccuzzi, G.; Tabaton, M. AGEs/RAGE complex upregulates BACE1 via NF-kappaB pathway activation Neurobiol. Aging 2012, 33, 196.e13-196.327 10.1016/j.neurobiolaging.2010.05.026
-
(2012)
Neurobiol. Aging
, vol.33
-
-
Guglielmotto, M.1
Aragno, M.2
Tamagno, E.3
Vercellinatto, I.4
Visentin, S.5
Medana, C.6
Catalano, M.G.7
Smith, M.A.8
Perry, G.9
Danni, O.10
Boccuzzi, G.11
Tabaton, M.12
-
119
-
-
84918591171
-
A review on Alzheimer's disease pathophysiology and its management: An update
-
Kumar, A.; Singh, A.; Ekavali A review on Alzheimer's disease pathophysiology and its management: an update Pharmacol. Rep. 2015, 67, 195-203 10.1016/j.pharep.2014.09.004
-
(2015)
Pharmacol. Rep.
, vol.67
, pp. 195-203
-
-
Kumar, A.1
Singh, A.2
Ekavali3
-
120
-
-
73949088883
-
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction
-
Takuma, K.; Fang, F.; Zhang, W.; Yan, S.; Fukuzaki, E.; Du, H.; Sosunov, A.; McKhann, G.; Funatsu, Y.; Nakamichi, N.; Nagai, T.; Mizoguchi, H.; Ibi, D.; Hori, O.; Ogawa, S.; Stern, D. M.; Yamada, K.; Yan, S. S. RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 20021-20026 10.1073/pnas.0905686106
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 20021-20026
-
-
Takuma, K.1
Fang, F.2
Zhang, W.3
Yan, S.4
Fukuzaki, E.5
Du, H.6
Sosunov, A.7
McKhann, G.8
Funatsu, Y.9
Nakamichi, N.10
Nagai, T.11
Mizoguchi, H.12
Ibi, D.13
Hori, O.14
Ogawa, S.15
Stern, D.M.16
Yamada, K.17
Yan, S.S.18
-
121
-
-
84899516443
-
Effect of TTP488 in patients with mild to moderate Alzheimer's disease
-
Burstein, A. H.; Grimes, I.; Galasko, D. R.; Aisen, P. S.; Sabbagh, M.; Mjalli, A. M. Effect of TTP488 in patients with mild to moderate Alzheimer's disease BMC Neurol. 2014, 14, 12 10.1186/1471-2377-14-12
-
(2014)
BMC Neurol.
, vol.14
, pp. 12
-
-
Burstein, A.H.1
Grimes, I.2
Galasko, D.R.3
Aisen, P.S.4
Sabbagh, M.5
Mjalli, A.M.6
-
122
-
-
80052258842
-
PF-04494700, an oral inhibitor of receptor for advanced glycation end products (RAGE), in Alzheimer disease
-
Sabbagh, M. N.; Agro, A.; Bell, J.; Aisen, P. S.; Schweizer, E.; Galasko, D. PF-04494700, an oral inhibitor of receptor for advanced glycation end products (RAGE), in Alzheimer disease Alzheimer Dis. Assoc. Disord. 2011, 25, 206-212 10.1097/WAD.0b013e318204b550
-
(2011)
Alzheimer Dis. Assoc. Disord.
, vol.25
, pp. 206-212
-
-
Sabbagh, M.N.1
Agro, A.2
Bell, J.3
Aisen, P.S.4
Schweizer, E.5
Galasko, D.6
-
123
-
-
84870238175
-
Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's disease
-
Lee, Y. S.; Kim, H.; Kim, Y. H.; Roh, E. J.; Han, H.; Shin, K. J. Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's disease Bioorg. Med. Chem. Lett. 2012, 22, 7555-7561 10.1016/j.bmcl.2012.10.022
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 7555-7561
-
-
Lee, Y.S.1
Kim, H.2
Kim, Y.H.3
Roh, E.J.4
Han, H.5
Shin, K.J.6
-
124
-
-
84868588005
-
Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors
-
Han, Y. T.; Choi, G. I.; Son, D.; Kim, N. J.; Yun, H.; Lee, S.; Chang, D. J.; Hong, H. S.; Kim, H.; Ha, H. J.; Kim, Y. H.; Park, H. J.; Lee, J.; Suh, Y. G. Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors J. Med. Chem. 2012, 55, 9120-9135 10.1021/jm300172z
-
(2012)
J. Med. Chem.
, vol.55
, pp. 9120-9135
-
-
Han, Y.T.1
Choi, G.I.2
Son, D.3
Kim, N.J.4
Yun, H.5
Lee, S.6
Chang, D.J.7
Hong, H.S.8
Kim, H.9
Ha, H.J.10
Kim, Y.H.11
Park, H.J.12
Lee, J.13
Suh, Y.G.14
-
125
-
-
84947127283
-
Design, synthesis, and biological evaluation of pyrimidine-2-carboxamide analogs: Investigation for novel RAGE inhibitors with reduced hydrophobicity and toxicity
-
Kim, S. H.; Han, Y. T. Design, synthesis, and biological evaluation of pyrimidine-2-carboxamide analogs: investigation for novel RAGE inhibitors with reduced hydrophobicity and toxicity Arch. Pharmacal Res. 2015, 38, 1952-1962 10.1007/s12272-015-0596-5
-
(2015)
Arch. Pharmacal Res.
, vol.38
, pp. 1952-1962
-
-
Kim, S.H.1
Han, Y.T.2
-
126
-
-
84921377083
-
Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE)
-
Han, Y. T.; Kim, K.; Son, D.; An, H.; Kim, H.; Lee, J.; Park, H. J.; Lee, J.; Suh, Y. G. Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE) Bioorg. Med. Chem. 2015, 23, 579-587 10.1016/j.bmc.2014.12.003
-
(2015)
Bioorg. Med. Chem.
, vol.23
, pp. 579-587
-
-
Han, Y.T.1
Kim, K.2
Son, D.3
An, H.4
Kim, H.5
Lee, J.6
Park, H.J.7
Lee, J.8
Suh, Y.G.9
-
127
-
-
84898654833
-
Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE)
-
Han, Y. T.; Kim, K.; Choi, G. I.; An, H.; Son, D.; Kim, H.; Ha, H. J.; Son, J. H.; Chung, S. J.; Park, H. J.; Lee, J.; Suh, Y. G. Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE) Eur. J. Med. Chem. 2014, 79, 128-142 10.1016/j.ejmech.2014.03.072
-
(2014)
Eur. J. Med. Chem.
, vol.79
, pp. 128-142
-
-
Han, Y.T.1
Kim, K.2
Choi, G.I.3
An, H.4
Son, D.5
Kim, H.6
Ha, H.J.7
Son, J.H.8
Chung, S.J.9
Park, H.J.10
Lee, J.11
Suh, Y.G.12
-
128
-
-
84937521485
-
6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE)
-
Choi, K.; Lim, K. S.; Shin, J.; Kim, S. H.; Suh, Y. G.; Hong, H. S.; Kim, H.; Ha, H. J.; Kim, Y. H.; Lee, J.; Lee, J. 6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE) Bioorg. Med. Chem. 2015, 23, 4919-4935 10.1016/j.bmc.2015.05.022
-
(2015)
Bioorg. Med. Chem.
, vol.23
, pp. 4919-4935
-
-
Choi, K.1
Lim, K.S.2
Shin, J.3
Kim, S.H.4
Suh, Y.G.5
Hong, H.S.6
Kim, H.7
Ha, H.J.8
Kim, Y.H.9
Lee, J.10
Lee, J.11
-
130
-
-
85029542098
-
-
WO2001092210
-
Mjalli, A. M. M.; Gopalaswamy, R.; Avor, K.; Wysong, C.; Patron, A. Method for the Synthesis of Compounds of Formula I and Their Uses Thereof. WO2001092210, 2002.
-
(2002)
Method for the Synthesis of Compounds of Formula i and Their Uses Thereof
-
-
Mjalli, A.M.M.1
Gopalaswamy, R.2
Avor, K.3
Wysong, C.4
Patron, A.5
-
131
-
-
85029470472
-
-
WO2003075921
-
Mjalli, A. M. M.; Andrews, R. C.; Gopalaswamy, R.; Hari, A.; Avor, K.; Qabaja, G.; Guo, X. C.; Gupta, S.; Jones, D. R.; Chen, X. Mono- and Bicyclic Azole Derivatives that Inhibit the Interaction of Ligands with Rage. WO2003075921, 2003.
-
(2003)
Mono- And Bicyclic Azole Derivatives That Inhibit the Interaction of Ligands with Rage
-
-
Mjalli, A.M.M.1
Andrews, R.C.2
Gopalaswamy, R.3
Hari, A.4
Avor, K.5
Qabaja, G.6
Guo, X.C.7
Gupta, S.8
Jones, D.R.9
Chen, X.10
-
133
-
-
84880918230
-
Structure-activity relationships of small molecule inhibitors of RAGE-Aβ binding
-
Ross, N. T.; Deane, R.; Perry, S.; Miller, B. L. Structure-activity relationships of small molecule inhibitors of RAGE-Aβ binding Tetrahedron 2013, 69, 7653-7658 10.1016/j.tet.2013.05.079
-
(2013)
Tetrahedron
, vol.69
, pp. 7653-7658
-
-
Ross, N.T.1
Deane, R.2
Perry, S.3
Miller, B.L.4
-
134
-
-
84906963073
-
Contribution of receptor for advanced glycation end products to vasculature-protecting effects of exercise training in aged rats
-
Gu, Q.; Wang, B.; Zhang, X. F.; Ma, Y. P.; Liu, J. D.; Wang, X. Z. Contribution of receptor for advanced glycation end products to vasculature-protecting effects of exercise training in aged rats Eur. J. Pharmacol. 2014, 741, 186-194 10.1016/j.ejphar.2014.08.017
-
(2014)
Eur. J. Pharmacol.
, vol.741
, pp. 186-194
-
-
Gu, Q.1
Wang, B.2
Zhang, X.F.3
Ma, Y.P.4
Liu, J.D.5
Wang, X.Z.6
-
135
-
-
84959141396
-
A Novel, Multi-Target Natural Drug Candidate, Matrine, Improves Cognitive Deficits in Alzheimer's Disease Transgenic Mice by Inhibiting Abeta Aggregation and Blocking the RAGE/Abeta Axis
-
Cui, L.; Cai, Y.; Cheng, W.; Liu, G.; Zhao, J.; Cao, H.; Tao, H.; Wang, Y.; Yin, M.; Liu, T.; Liu, Y.; Huang, P.; Liu, Z.; Li, K.; Zhao, B. A Novel, Multi-Target Natural Drug Candidate, Matrine, Improves Cognitive Deficits in Alzheimer's Disease Transgenic Mice by Inhibiting Abeta Aggregation and Blocking the RAGE/Abeta Axis Mol. Neurobiol. 2017, 54, 1939-1952 10.1007/s12035-016-9783-8
-
(2017)
Mol. Neurobiol.
, vol.54
, pp. 1939-1952
-
-
Cui, L.1
Cai, Y.2
Cheng, W.3
Liu, G.4
Zhao, J.5
Cao, H.6
Tao, H.7
Wang, Y.8
Yin, M.9
Liu, T.10
Liu, Y.11
Huang, P.12
Liu, Z.13
Li, K.14
Zhao, B.15
-
136
-
-
84861742380
-
Receptor for advanced glycation end products (RAGE) functions as receptor for specific sulfated glycosaminoglycans, and anti-RAGE antibody or sulfated glycosaminoglycans delivered in vivo inhibit pulmonary metastasis of tumor cells
-
Mizumoto, S.; Takahashi, J.; Sugahara, K. Receptor for advanced glycation end products (RAGE) functions as receptor for specific sulfated glycosaminoglycans, and anti-RAGE antibody or sulfated glycosaminoglycans delivered in vivo inhibit pulmonary metastasis of tumor cells J. Biol. Chem. 2012, 287, 18985-18994 10.1074/jbc.M111.313437
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 18985-18994
-
-
Mizumoto, S.1
Takahashi, J.2
Sugahara, K.3
-
137
-
-
79951786934
-
Novel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosacea
-
Zhang, J.; Xu, X.; Rao, N. V.; Argyle, B.; McCoard, L.; Rusho, W. J.; Kennedy, T. P.; Prestwich, G. D.; Krueger, G. Novel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosacea PLoS One 2011, 6, e16658 10.1371/journal.pone.0016658
-
(2011)
PLoS One
, vol.6
, pp. e16658
-
-
Zhang, J.1
Xu, X.2
Rao, N.V.3
Argyle, B.4
McCoard, L.5
Rusho, W.J.6
Kennedy, T.P.7
Prestwich, G.D.8
Krueger, G.9
-
138
-
-
84865085648
-
S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis
-
Arumugam, T.; Ramachandran, V.; Gomez, S. B.; Schmidt, A. M.; Logsdon, C. D. S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis Clin. Cancer Res. 2012, 18, 4356-4364 10.1158/1078-0432.CCR-12-0221
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 4356-4364
-
-
Arumugam, T.1
Ramachandran, V.2
Gomez, S.B.3
Schmidt, A.M.4
Logsdon, C.D.5
-
139
-
-
85029526140
-
-
WO2015050984
-
Schmidt, A. M.; Ramasamy, R.; Shekhtman, A.; Rai, V.; Manigrasso, M. B. Amido and Heterocyclic Compounds as Modulators of Rage Activity and Uses Thereof. WO2015050984, 2014.
-
(2014)
Amido and Heterocyclic Compounds As Modulators of Rage Activity and Uses Thereof
-
-
Schmidt, A.M.1
Ramasamy, R.2
Shekhtman, A.3
Rai, V.4
Manigrasso, M.B.5
-
140
-
-
84884280876
-
Two beta-strands of RAGE participate in the recognition and transport of amyloid-beta peptide across the blood brain barrier
-
Kim, S. J.; Ahn, J. W.; Kim, H.; Ha, H. J.; Lee, S. W.; Kim, H. K.; Lee, S.; Hong, H. S.; Kim, Y. H.; Choi, C. Y. Two beta-strands of RAGE participate in the recognition and transport of amyloid-beta peptide across the blood brain barrier Biochem. Biophys. Res. Commun. 2013, 439, 252-257 10.1016/j.bbrc.2013.08.047
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.439
, pp. 252-257
-
-
Kim, S.J.1
Ahn, J.W.2
Kim, H.3
Ha, H.J.4
Lee, S.W.5
Kim, H.K.6
Lee, S.7
Hong, H.S.8
Kim, Y.H.9
Choi, C.Y.10
-
141
-
-
84877010696
-
Interaction of the S100A6 mutant (C3S) with the v domain of the receptor for advanced glycation end products (RAGE)
-
Mohan, S. K.; Gupta, A. A.; Yu, C. Interaction of the S100A6 mutant (C3S) with the V domain of the receptor for advanced glycation end products (RAGE) Biochem. Biophys. Res. Commun. 2013, 434, 328-333 10.1016/j.bbrc.2013.03.049
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.434
, pp. 328-333
-
-
Mohan, S.K.1
Gupta, A.A.2
Yu, C.3
-
142
-
-
85002681347
-
The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins
-
Yatime, L.; Betzer, C.; Jensen, R. K.; Mortensen, S.; Jensen, P. H.; Andersen, G. R. The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins Structure 2016, 24, 2043-2052 10.1016/j.str.2016.09.011
-
(2016)
Structure
, vol.24
, pp. 2043-2052
-
-
Yatime, L.1
Betzer, C.2
Jensen, R.K.3
Mortensen, S.4
Jensen, P.H.5
Andersen, G.R.6
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