Association of 2184AG polymorphism in the RAGE gene with diabetic nephropathy in Chinese patients with type 2 diabetes

Journal of Diabetes Research

Volumn 2015, Issue , 2015, Pages

  Cai, Wei ^a   Li, Jian ^b   Xu, Ji Xiong ^a   Liu, Ying ^a   Zhang, Wei ^c   Xiao, Jun Ren ^a   Zhu, Ling Yan ^a   Liu, Jian Ying ^a  

^a NANCHANG UNIVERSITY   (China)

^b Xinxiang People's Hospital   (China)

^c First Affiliated Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; GENOMIC DNA;

ADULT; ARTICLE; DIABETIC NEPHROPATHY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HAN CHINESE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR PATHOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; PILOT STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; AGED; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM;

ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84950135003     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2015/310237     Document Type: Article

References (29)

1. K. R. Tuttle, G. L. Bakris, R. W. Bilous et al., "Diabetic kidney disease: a report from an ADA Consensus Conference," American Journal of Kidney Diseases, vol. 64, no. 4, pp. 510-533, 2014.
2. E. R. Seaquist, F. C. Goetz, S. Rich, and J. Barbosa, "Familial clustering of diabetic kidney disease: evidence for genetic susceptibility to diabetic nephropathy,"The New England Journal of Medicine, vol. 320, no. 18, pp. 1161-1165, 1989.
3. T. Soulis, V. Thallas, S. Youssef et al., "Advanced glycation end products and their receptors co-localise in rat organs susceptible to diabetic microvascular injury," Diabetologia, vol. 40, no. 6, pp. 619-628, 1997.
4. Y. Kaida, K. Fukami, T. Matsui et al., "DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy," Diabetes, vol. 62, no. 9, pp. 3241-3250, 2013.
5. G. Basta, G. Lazzerini, M. Massaro et al., "Advanced glycation end products activate endothelium through signal transduction receptor RAGE: amechanism for amplification of inflammatory responses," Circulation, vol. 105, no. 7, pp. 816-822, 2002.
6. M. T. Coughlan, D. R. Thorburn, S. A. Penfold et al., "Rageinduced cytosolic ROS promote mitochondrial superoxide generation in diabetes," Journal of the American Society of Nephrology, vol. 20, no. 4, pp. 742-752, 2009.
7. N. Reiniger, K. Lau, D. McCalla et al., "Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse," Diabetes, vol. 59, no. 8, pp. 2043-2054, 2010.
8. S. F. Yan, R. Ramasamy, and A. M. Schmidt, "The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature," Circulation Research, vol. 106, no. 5, pp. 842-853, 2010.
9. M. B.Manigrasso, J. Juranek, R. Ramasamy, and A. M. Schmidt, "Unlocking the biology of RAGE in diabetic microvascular complications," Trends in Endocrinology and Metabolism, vol. 25, no. 1, pp. 15-22, 2014.
10. K. Kanková, J. Záhejsky, I. Márová et al., "Polymorphisms in the RAGE gene influence susceptibility to diabetes-associated microvascular dermatoses in NIDDM," Journal of Diabetes and its Complications, vol. 15, no. 4, pp. 185-192, 2001.
11. K. Kanková, I. Márová, J. Záhejsky et al., "Polymorphisms 1704G/T and 2184A/G in the RAGE gene are associated with antioxidant status," Metabolism: Clinical and Experimental, vol. 50, no. 10, pp. 1152-1160, 2001.
12. A. S. Levey, J. Coresh, E. Balk et al., "National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification," Annals of Internal Medicine, vol. 139, no. 2, pp. 137-147, 2003.
13. K. Kanková, A. Stejskalová, L. Pácal et al., "Genetic risk factors for diabetic nephropathy on chromosomes 6p and 7q identified by the set-association approach," Diabetologia, vol. 50, no. 5, pp. 990-999, 2007.
14. Z.X. Ng, U. R. Kuppusamy, I. Tajunisah, K.C. S. Fong, A. C. A. Koay, and K. H. Chua, "2245G/A polymorphism of the receptor for advanced glycation end-products (RAGE) gene is associated with diabetic retinopathy in the Malaysian population," British Journal of Ophthalmology, vol. 96, no. 2, pp. 289-292, 2012.
15. K. Kanková, A. Stejskalová, M. Hertlová, and V. Znojil, "Haplotype analysis of the RAGE gene: identification of a haplotype marker for diabetic nephropathy in type 2 diabetes mellitus," Nephrology Dialysis Transplantation, vol. 20, pp. 1093-1102, 2005.
16. L. Liu and K. Xiang, "RAGE Gly82Ser polymorphism in diabetic microangiopathy," Diabetes Care, vol. 22, no. 4, article 646, 1999.
17. X. Jixiong, X. Bilin, Y. Minggong, and L. Shuqin, "-429T/C and -374T/A polymorphisms of RAGE gene promoter are not associated with diabetic retinopathy in Chinese patients with type 2 diabetes," Diabetes Care, vol. 26, no. 9, pp. 2696-2697, 2003.
18. B. I. Hudson, M. H. Stickland, T. S. Futers, and P. J. Grant, "Effects of novel polymorphisms in the RAGE gene on transcriptional regulation and their association with diabetic retinopathy," Diabetes, vol. 50, no. 6, pp. 1505-1511, 2001.
19. Z. X. Ng, U. R. Kuppusamy, I. Tajunisah, K. C. S. Fong, and K. H. Chua, "Association analysis of -429T/C and -374T/A polymorphisms of receptor of advanced glycation end products (RAGE) gene in Malaysian with type 2 diabetic retinopathy," Diabetes Research and Clinical Practice, vol. 95, no. 3, pp. 372-377, 2012.
20. P. Kang, C. Tian, and C. Jia, "Association of RAGE gene polymorphisms with type 2 diabetes mellitus, diabetic retinopathy and diabetic nephropathy," Gene, vol. 500, no. 1, pp. 1-9, 2012.
21. Z. Shi, W. Lu, and G. Xie, "Association between the RAGE gene -374T/A, -429T/C polymorphisms and diabetic nephropathy: a meta-analysis," Renal Failure, vol. 37, no. 5, pp. 751-756, 2015.
22. A. Z. Kalea, A. M. Schmidt, and B. I. Hudson, "RAGE: a novel biological and genetic marker for vascular disease," Clinical Science, vol. 116, no. 8, pp. 621-637, 2009.
23. A. Z. Kalea, A. M. Schmidt, and B. I. Hudson, "Alternative splicing of RAGE: roles in biology and disease," Frontiers in Bioscience, vol. 16, no. 7, pp. 2756-2770, 2011.
24. H. Yonekura, Y. Yamamoto, S. Sakurai et al., "Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury," Biochemical Journal, vol. 370, no. 3, pp. 1097-1109, 2003.
25. M. Kalousová, M. Jáchymová, M. Oto et al., "Receptor for advanced glycation end products-soluble form and gene polymorphisms in chronic haemodialysis patients," Nephrology Dialysis Transplantation, vol. 22, no. 7, pp. 2020-2026, 2007.
26. R. Retnakaran, C. A. Cull, K. I. Thorne, A. I. Adler, and R. R. Holman, "Risk factors for renal dysfunction in type 2 diabetes: U.K. Prospective diabetes study 74," Diabetes, vol. 55, no. 6, pp. 1832-1839, 2006.
27. R. J. MacIsaac, C. Tsalamandris, S. Panagiotopoulos, T. J. Smith, K. J. McNeil, and G. Jerums, "Nonalbuminuric renal insufficiency in type 2 diabetes," Diabetes Care, vol. 27, no. 1, pp. 195-200, 2004.
28. National Kidney Foundation, "KDOQI clinical practice guidelines and clinical practice recommendations for diabetes and chronic kidney disease," American Journal of Kidney Diseases, vol. 49, no. 2, Supplement 2, pp. S12-S154, 2007.
29. F. He, X. Xia, X. F. Wu, X. Q. Yu, and F. X. Huang, "Diabetic retinopathy in predicting diabetic nephropathy in patients with type 2 diabetes and renal disease: a meta-analysis," Diabetologia, vol. 56, no. 3, pp. 457-466, 2013.