Site-specific blockade of RAGE-Vd prevents amyloid-β oligomer neurotoxicity

Journal of Neuroscience

Volumn 28, Issue 20, 2008, Pages 5149-5158

  Sturchler, Emmanuel ^a   Galichet, Arnaud ^a   Weibel, Mirjam ^a   Leclerc, Estelle ^b   Heizmann, Claus W ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Amyloid ; Apoptosis; Cortical neurons; Ig like domains; RAGE

Indexed keywords

AMYLOID BETA PROTEIN; CARRIER PROTEIN; IMMUNOGLOBULIN; MITOGEN ACTIVATED PROTEIN KINASE 3; OLIGOMER; PROTEIN RECEPTOR FOR ADVANCED GLYCATION END PRODUCT; UNCLASSIFIED DRUG; ADVANCED GLYCOSYLATION END PRODUCT RECEPTOR; ADVANCED GLYCOSYLATION END-PRODUCT RECEPTOR; ANTIBODY; IMMUNOGLOBULIN RECEPTOR; NEUROTOXIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL DEATH; CELL SURVIVAL; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; ALZHEIMER DISEASE; ANIMAL; ANTIBODY SPECIFICITY; BINDING SITE; BRAIN; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; IMMUNOLOGY; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; RAT; SENILE PLAQUE; TUMOR CELL LINE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANTIBODIES; ANTIBODY SPECIFICITY; APOPTOSIS; BINDING SITES; BRAIN; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; NEURONS; NEUROTOXINS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, IMMUNOLOGIC; SENILE PLAQUES;

EID: 45549097081     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4878-07.2008     Document Type: Article

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