Receptor for advanced glycation end products (RAGE) functions as receptor for specific sulfated glycosaminoglycans, and anti-RAGE antibody or sulfated glycosaminoglycans delivered in vivo inhibit pulmonary metastasis of tumor cells

Journal of Biological Chemistry

Volumn 287, Issue 23, 2012, Pages 18985-18994

  Mizumoto, Shuji ^a   Takahashi, Jun ^a   Sugahara, Kazuyuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCTS; CHONDROITIN SULFATES; DOSE-DEPENDENT MANNER; E-DISACCHARIDE; HEPARAN SULFATES; IN-VIVO; INTRAVENOUS INJECTIONS; LEWIS LUNG CARCINOMATA; LUNG METASTASIS; METASTATIC POTENTIAL; MOLECULAR MECHANISM; MOLECULAR TARGETS; PHAGE DISPLAY; PRE-INCUBATION; SULFATED GLYCOSAMINOGLYCANS; TUMOR CELL LINES; TUMOR CELLS; TUMOR METASTASIS;

ANTIBODIES; BIOLOGICAL ORGANS; CELL CULTURE; CELL MEMBRANES; TUMORS;

PATHOLOGY;

ADVANCED GLYCATION END PRODUCT RECEPTOR; CHONDROITIN SULFATE; DISACCHARIDE; E DISACCHARIDE PROTEIN; GLYCOSAMINOGLYCAN POLYSULFATE; HEPARAN SULFATE; IMMUNOGLOBULIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY GAG; MONOCLONAL ANTIBODY RAGE; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOMA CELL; CELL SURFACE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG TARGETING; IN VIVO CULTURE; LEWIS CARCINOMA; LUNG METASTASIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR CELL;

ANIMALS; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; DECAPODIFORMES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOSAMINOGLYCANS; LUNG NEOPLASMS; MALE; MICE; NEOPLASM METASTASIS; NEOPLASM PROTEINS; RECEPTORS, IMMUNOLOGIC;

CEPHALOPODA;

EID: 84861742380     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.313437     Document Type: Article

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