Correction of a pathogenic gene mutation in human embryos

Nature

Volumn 548, Issue 7668, 2017, Pages 413-419

  Ma, Hong ^a   Marti Gutierrez, Nuria ^a   Park, Sang Wook ^b   Wu, Jun ^c   Lee, Yeonmi ^a   Suzuki, Keiichiro ^c   Koski, Amy ^a   Ji, Dongmei ^a   Hayama, Tomonari ^a   Ahmed, Riffat ^a   Darby, Hayley ^a   Van Dyken, Crystal ^a   Li, Ying ^a   Kang, Eunju ^a   Park, A Reum ^b   Kim, Daesik ^d   Kim, Sang Tae ^b   Gong, Jianhui ^e,f,g   Gu, Ying ^e,f,g   Xu, Xun ^e,f,g   Battaglia, David ^a   Krieg, Sacha A ^a   Lee, David M ^a   Wu, Diana H ^a   Wolf, Don P ^a   Heitner, Stephen B ^h   Belmonte, Juan Carlos Izpisua ^c   Amato, Paula ^a   Kim, Jin Soo ^b,d   Kaul, Sanjiv ^h   Mitalipov, Shoukhrat ^a,h   more..

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Institute for Basic Science   (South Korea)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d Seoul National University   (South Korea)

^e BGI SHENZHEN   (China)

^f BGI SHENZHEN   (China)

^g BGI Qingdao ^*  (China)

^h OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MYOSIN-BINDING PROTEIN C;

ADULT; ALLELE; BLASTOCYST; CELL CYCLE S PHASE; CELL DIVISION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DNA TEMPLATE; DOUBLE STRANDED DNA BREAK; GENE EDITING; GENE TARGETING; GENETIC COMPLEMENTATION; GENETICS; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MALE; MAMMALIAN EMBRYO; METABOLISM; MOSAICISM; MUTATION; PATHOLOGY; PROCEDURES; RECOMBINATION REPAIR; ZYGOTE;

ADULT; ALLELES; BLASTOCYST; CARRIER PROTEINS; CELL DIVISION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; DNA BREAKS, DOUBLE-STRANDED; EMBRYO, MAMMALIAN; GENE EDITING; GENE TARGETING; GENETIC COMPLEMENTATION TEST; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; MOSAICISM; MUTATION; RECOMBINATIONAL DNA REPAIR; S PHASE; TEMPLATES, GENETIC; ZYGOTE;

EID: 85026999487     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature23305     Document Type: Article

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