Hypersensitivity of Primordial Germ Cells to Compromised Replication-Associated DNA Repair Involves ATM-p53-p21 Signaling

PLoS Genetics

Volumn 10, Issue 7, 2014, Pages

  Luo, Yunhai ^a   Hartford, Suzanne A ^a,b   Zeng, Ruizhu ^a,c   Southard, Teresa L ^a   Shima, Naoko ^a,d   Schimenti, John C ^a  

^a Department of Obstetrics Gynecology   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN P21; PROTEIN P53; ATM PROTEIN; ATM PROTEIN, MOUSE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; EMBRYO; FANCONI ANEMIA; FEMALE; GENE MUTATION; GENOMIC INSTABILITY; HISTOLOGY; HUMAN; HYPERSENSITIVITY; HYPOGONADISM; IMMUNOHISTOCHEMISTRY; MALE; MEIOSIS; MOUSE; NEWBORN; NICK END LABELING; NONHUMAN; PHENOTYPE; PRIMORDIAL GERM CELL; TESTIS DISEASE; WILD TYPE; ANIMAL; BIOSYNTHESIS; GENETICS; GERM CELL; METABOLISM; MUTATION; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; DNA REPAIR; DNA REPLICATION; FANCONI ANEMIA; GENOMIC INSTABILITY; GERM CELLS; HUMANS; HYPOGONADISM; MICE; MUTATION; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84905460409     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004471     Document Type: Article

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