Structural Basis for Xenosiderophore Utilization by the Human Pathogen Staphylococcus aureus

ACS Infectious Diseases

Volumn 3, Issue 7, 2017, Pages 542-553

  Endicott, Nathaniel P ^a   Lee, Eries ^a   Wencewicz, Timothy A ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

antivirulence; deferoxamine; iron; iron overload disease; MRSA; sideromycin; siderophore; siderophore antibiotic conjugate; Staphylococcus aureus; xenosiderophore

Indexed keywords

BACTERIAL PROTEIN; DANOXAMINE; DEFEROXAMINE; FERRIC ION; FERRIOXAMINE; HYDROXAMIC ACID DERIVATIVE; PROTEIN FHUD1; PROTEIN FHUD2; SIDEROMYCIN; SIDEROPHORE; UNCLASSIFIED DRUG; CARRIER PROTEIN; CATION; IRON; PERIPLASMIC BINDING PROTEIN; PROTEIN BINDING;

ACYLATION; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL STRAIN; BINDING AFFINITY; BINDING ASSAY; CHEMICAL MODIFICATION; COMPETITIVE BINDING ASSAY; CONTROLLED STUDY; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; ANALOGS AND DERIVATIVES; BINDING COMPETITION; DRUG EFFECTS; GENE EXPRESSION; GENETICS; KINETICS; METABOLISM; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR MODEL; STATIC ELECTRICITY; SYNTHESIS;

BINDING, COMPETITIVE; CATIONS; DEFEROXAMINE; GENE EXPRESSION; IRON; KINETICS; MEMBRANE TRANSPORT PROTEINS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MODELS, MOLECULAR; PERIPLASMIC BINDING PROTEINS; PROTEIN BINDING; SIDEROPHORES; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85023761390     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.7b00036     Document Type: Article

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