Comparing the potential renal protective activity of desferrioxamine B and the novel chelator desferrioxamine B-N-(3-hydroxyadamant-1-yl) carboxamide in a cell model of myoglobinuria

Biochemical Journal

Volumn 435, Issue 3, 2011, Pages 669-677

  Groebler, Ludwig K ^a   Liu, Joe ^a   Shanu, Anu ^a   Codd, Rachel ^a   Witting, Paul K ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Acute renal failure; Antioxidant; Burn; Metal chelation therapy; Myoglobinuria; Oxidative stress

Indexed keywords

BETA ACTIN; DEFEROXAMINE; DESFERRIOXAMINE B N (3 HYDROXYADAMANT 1 YL)CARBOXAMIDE; DIHYDRORHODAMINE 123; HAEM OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; MYOGLOBIN; NITROXIDE; OXYGENASE; PROTECTIVE AGENT; RENAL PROTECTIVE AGENT; TRANSFERRIN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CHELATION; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; ENDOCYTOSIS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; KIDNEY EPITHELIUM; KIDNEY FUNCTION; KIDNEY TUBULE EPITHELIUM; MYOGLOBINURIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION;

ANIMALS; CELL LINE; CHELATING AGENTS; DEFEROXAMINE; DOGS; ENDOCYTOSIS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; KIDNEY TUBULES; MOLECULAR STRUCTURE; MYOGLOBIN; MYOGLOBINURIA;

EID: 79954515321     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101728     Document Type: Article

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