Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1863, Issue 9, 2017, Pages 2093-2110

  Asimakopoulou, Anastasia ^a   Fülöp, Annabelle ^b   Borkham Kamphorst, Erawan ^a   de Leur, Eddy Van ^a   Gassler, Nikolaus ^c   Berger, Thorsten ^d   Beine, Birte ^e,f   Meyer, Helmut E ^e   Mak, Tak W ^d   Hopf, Carsten ^b   Henkel, Corinna ^e,f,g   Weiskirchen, Ralf ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b MANNHEIM UNIVERSITY OF APPLIED SCIENCES   (Germany)

^c Institute of Pathology   (Germany)

^d PRINCESS MARGARET HOSPITAL   (Canada)

^e LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

^f RUHR UNIVERSITY BOCHUM   (Germany)

^g BRUKER DALTONIK GMBH   (Germany)

Author keywords

Arachidonic acid; Dietary model; Fatty acid binding proteins; GO analysis; Iron pool; Lipidomics; Liver; Mitochondria; Peroxisomes; Phosphoinositide (3,4,5) triphosphate; Proteomics

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBOXYLIC ACID; CHOLINE; GLYCEROPHOSPHOLIPID; HEMOGLOBIN BETA CHAIN; HEMOGLOBIN SUBUNIT BETA 2; HIGH MOBILITY GROUP B1 PROTEIN; MESSENGER RNA; METHIONINE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; REACTIVE OXYGEN METABOLITE; SPHINGOMYELIN; THYMIDINE PHOSPHORYLASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; LCN2 PROTEIN, MOUSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CELL PERMEABILIZATION; CONTROLLED STUDY; FATTY LIVER; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE ONTOLOGY; LIPID PEROXIDATION; LIVER CELL; LIVER WEIGHT; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NECROSIS; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; WEIGHT GAIN; WEIGHT REDUCTION; WESTERN BLOTTING; ANIMAL; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; LIVER MITOCHONDRION; METABOLISM; OXIDATIVE STRESS; PATHOLOGY;

ANIMALS; APOPTOSIS; FATTY LIVER; GENE EXPRESSION REGULATION; HEPATOCYTES; LIPOCALIN-2; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, KNOCKOUT; MITOCHONDRIA, LIVER; OXIDATIVE STRESS; PEROXISOMES; TRIGLYCERIDES;

EID: 85021242639     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2017.04.006     Document Type: Article

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