Knockdown of FABP5 mRNA decreases cellular cholesterol levels and results in decreased apoB100secretion and triglyceride accumulation in ARPE-19 cells

Laboratory Investigation

Volumn 90, Issue 6, 2010, Pages 906-914

  Wu, Tinghuai ^a   Tian, Jane ^a   Cutler, Roy G ^b   Telljohann, Richard S ^b   Bernlohr, David A ^c   Mattson, Mark P ^b   Handa, James T ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Departments of Neuroscience   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

ApoB; Cholesterol; FABP5; RPE; SiRNA; Triglycerides

Indexed keywords

APOLIPOPROTEIN B100; CHOLESTEROL; CHOLESTEROL ESTER; FABP5 PROTEIN, HUMAN; FATTY ACID; FATTY ACID BINDING PROTEIN; LIPOPROTEIN; MESSENGER RNA; PHOSPHOLIPID; PRIMER DNA; SMALL INTERFERING RNA; TRIACYLGLYCEROL;

ANIMAL; ARTICLE; CELL LINE; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY; PIGMENT EPITHELIUM; RETINA MACULA DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION;

ANIMALS; APOLIPOPROTEIN B-100; CELL LINE; CHOLESTEROL; CHOLESTEROL ESTERS; DNA PRIMERS; FATTY ACID-BINDING PROTEINS; FATTY ACIDS, NONESTERIFIED; HUMANS; LIPOPROTEINS; MACULAR DEGENERATION; MICE; PHOSPHOLIPIDS; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION; TRIGLYCERIDES;

EID: 77954589932     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2009.33     Document Type: Article

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