Nuclear Factor High-mobility Group Box1 Mediating the Activation of Toll-like Receptor 4 Signaling in Hepatocytes in the Early Stage of Non-alcoholic Fatty Liver Disease in Mice

Journal of Clinical and Experimental Hepatology

Volumn 1, Issue 2, 2011, Pages 123-124

  Li, L ^a   Chen, L ^a   Hu, L ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; FATTY ACID; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; NEUTRALIZING ANTIBODY; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL INFILTRATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; FATTY LIVER; FOOD INTAKE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; KUPFFER CELL; LIPID DIET; LIVER CELL; LIVER PARENCHYMA; MACROPHAGE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE;

EID: 83455220815     PISSN: 09736883     EISSN: 22133453     Source Type: Journal    
DOI: 10.1016/S0973-6883(11)60136-9     Document Type: Article

References (5)

1. Miura K, Seki E, Ohnishi H, Brenner DA Role of toll-like receptors and their downstream molecules in the development of nonalcoholic fatty liver disease. Gastroenterol Res Pract 2010, Vol 2010, Article ID 362847:9 pages.
2. Kodama Y, Brenner DA c-Jun N-terminal kinase signaling in the pathogenesis of nonalcoholic fatty liver disease: multiple roles in multiple steps. Hepatology 2009, 49:6-8.
3. Seki E, Brenner DA Toll-like receptors and adaptor molecules in liver disease: update. Hepatology 2008, 48:322-335.
4. Rivera CA, Adegboyega P, van Rooijen N, Tagalicud A, Allman M, Wallace M Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis. J Hepatol 2007, 47:571-579.
5. Li L, Chen L, Hu L, et al. Nuclear factor high-mobility group box1 mediating the activation of toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice. Hepatology 2011, July 11, [Epub ahead of print].