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Volumn 6, Issue 8, 2011, Pages

Increased diacylglycerols characterize hepatic lipid changes in progression of human nonalcoholic fatty liver disease; comparison to a murine model

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; LIVER EXTRACT; PHOSPHATIDYLINOSITOL; PHOSPHOLIPID; GLYCEROPHOSPHOLIPID; LIPID;

EID: 79961211515     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022775     Document Type: Article
Times cited : (127)

References (35)
  • 1
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: from steatosis to cirrhosis
    • Farrell GC, Larter CZ, (2006) Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 43 (2) Suppl 1: S99-S112.
    • (2006) Hepatology , vol.43 , Issue.2 SUPPL. 1 , pp. 99-112
    • Farrell, G.C.1    Larter, C.Z.2
  • 2
    • 49649092692 scopus 로고    scopus 로고
    • Obesity and diabetes epidemics: cancer repercussions
    • Hjartaker A, Langseth H, Weiderpass, E, (2008) Obesity and diabetes epidemics: cancer repercussions. Adv Exp Med Biol 630: 72-93.
    • (2008) Adv Exp Med Biol , vol.630 , pp. 72-93
    • Hjartaker, A.1    Langseth, H.2    Weiderpass, E.3
  • 3
    • 33745107554 scopus 로고    scopus 로고
    • Mechanisms of Disease: hepatic steatosis in type 2 diabetes-pathogenesis and clinical relevance
    • Roden M, (2006) Mechanisms of Disease: hepatic steatosis in type 2 diabetes-pathogenesis and clinical relevance. Nat Clin Pract Endocrinol Metab2 (6): 335-348.
    • (2006) Nat Clin Pract Endocrinol Metab , vol.2 , Issue.6 , pp. 335-348
    • Roden, M.1
  • 4
    • 56649094325 scopus 로고    scopus 로고
    • Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease
    • Harmeet M, Gores, GJ, (2008) Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease. Seminars in Liver Disease 28 (4): 360-369.
    • (2008) Seminars in Liver Disease , vol.28 , Issue.4 , pp. 360-369
    • Harmeet, M.1    Gores, G.J.2
  • 5
    • 33646121972 scopus 로고    scopus 로고
    • The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis
    • Li Z, Agellon LB, Allen TM, Umeda M, Jewell L, al et, (2006) The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. Cell Metabol 3: 321-331.
    • (2006) Cell Metabol , vol.3 , pp. 321-331
    • Li, Z.1    Agellon, L.B.2    Allen, T.M.3    Umeda, M.4    Jewell, L.5
  • 6
    • 63249121641 scopus 로고    scopus 로고
    • Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver
    • Kotronen A, Seppanen-Laakso T, Westerbacka J, Kiviluoto T, Arola J, et al. (2009) Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver. Diabetes 58: 203-208.
    • (2009) Diabetes , vol.58 , pp. 203-208
    • Kotronen, A.1    Seppanen-Laakso, T.2    Westerbacka, J.3    Kiviluoto, T.4    Arola, J.5
  • 7
    • 0029066265 scopus 로고
    • Effects of the obese gene product on body weight regulation in ob/ob mice
    • Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, et al. (1995) Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 540-543.
    • (1995) Science , vol.269 , pp. 540-543
    • Pelleymounter, M.A.1    Cullen, M.J.2    Baker, M.B.3    Hecht, R.4    Winters, D.5
  • 8
    • 33644955272 scopus 로고    scopus 로고
    • Mouse models in non-alcoholic fatty liver disease and steatohepatitis research
    • Anstee QM, Goldin RD, (2006) Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. Int J Exp Pathol 87 (1): 1-16.
    • (2006) Int J Exp Pathol , vol.87 , Issue.1 , pp. 1-16
    • Anstee, Q.M.1    Goldin, R.D.2
  • 10
    • 33845457973 scopus 로고    scopus 로고
    • Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications
    • Rouzer CA, Ivanova PT, Byrne MO, Milne SB, Marnett LJ, al et, (2006) Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications. Biochemistry 45: 14795-14808.
    • (2006) Biochemistry , vol.45 , pp. 14795-14808
    • Rouzer, C.A.1    Ivanova, P.T.2    Byrne, M.O.3    Milne, S.B.4    Marnett, L.J.5
  • 11
    • 41249101849 scopus 로고    scopus 로고
    • Glycerophospholipid identification and quantitation by electrospray ionization mass spectrometry
    • Ivanova PT, Milne SB, Byrne MO, Xiang Y, Brown HA, (2007) Glycerophospholipid identification and quantitation by electrospray ionization mass spectrometry. Meth Enzymol 432: 21-57.
    • (2007) Meth Enzymol , vol.432 , pp. 21-57
    • Ivanova, P.T.1    Milne, S.B.2    Byrne, M.O.3    Xiang, Y.4    Brown, H.A.5
  • 12
    • 33746297150 scopus 로고    scopus 로고
    • Lipidomics: An analysis of cellular lipids by ESI-MS
    • Milne S, Ivanova P, Forrester J, Brown HA, (2006) Lipidomics: An analysis of cellular lipids by ESI-MS. Methods 39: 92-103.
    • (2006) Methods , vol.39 , pp. 92-103
    • Milne, S.1    Ivanova, P.2    Forrester, J.3    Brown, H.A.4
  • 13
    • 33846190698 scopus 로고    scopus 로고
    • Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm
    • Callender HL, Forrester JS, Ivanova P, Preininger A, Milne S, al et, (2007) Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm. Anal Chem 79: 263-272.
    • (2007) Anal Chem , vol.79 , pp. 263-272
    • Callender, H.L.1    Forrester, J.S.2    Ivanova, P.3    Preininger, A.4    Milne, S.5
  • 14
    • 67649962967 scopus 로고    scopus 로고
    • High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model
    • VanSaun MN, Lee IK, Washington K, Matrisian LM, Gorden DL, (2009) High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model. Amer J Pathol 175 (1): 355-364.
    • (2009) Amer J Pathol , vol.175 , Issue.1 , pp. 355-364
    • VanSaun, M.N.1    Lee, I.K.2    Washington, K.3    Matrisian, L.M.4    Gorden, D.L.5
  • 15
    • 77952721223 scopus 로고    scopus 로고
    • Identification of atypical ether-linked glycerophospholipid species in macrophages by mass spectrometry
    • Ivanova PT, Milne SB, Brown HA, (2010) Identification of atypical ether-linked glycerophospholipid species in macrophages by mass spectrometry. J Lipid Res 51: 1581-1590.
    • (2010) J Lipid Res , vol.51 , pp. 1581-1590
    • Ivanova, P.T.1    Milne, S.B.2    Brown, H.A.3
  • 16
    • 34249081124 scopus 로고    scopus 로고
    • Lipid profiling reveals glycerophospholipid remodeling in zymosan-stimulated macrophages
    • Rouzer CA, Ivanova PT, Byrne MO, Brown HA, Marnett LJ, (2007) Lipid profiling reveals glycerophospholipid remodeling in zymosan-stimulated macrophages. Biochemistry 46: 6026-6042.
    • (2007) Biochemistry , vol.46 , pp. 6026-6042
    • Rouzer, C.A.1    Ivanova, P.T.2    Byrne, M.O.3    Brown, H.A.4    Marnett, L.J.5
  • 17
    • 51549100425 scopus 로고    scopus 로고
    • Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase
    • Milne SB, Ivanova PT, Armstrong MD, Myers DS, Lubarda J, et al. (2008) Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase. Biochemistry 47: 9372-9379.
    • (2008) Biochemistry , vol.47 , pp. 9372-9379
    • Milne, S.B.1    Ivanova, P.T.2    Armstrong, M.D.3    Myers, D.S.4    Lubarda, J.5
  • 18
    • 70349214775 scopus 로고    scopus 로고
    • Lipidomics profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with α-synuclein genotype
    • Rappley I, Myers DS, Milne SB, Ivanova PT, LaVoie MJ, et al. (2009) Lipidomics profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with α-synuclein genotype. J Neurochem 111 (1): 15-25.
    • (2009) J Neurochem , vol.111 , Issue.1 , pp. 15-25
    • Rappley, I.1    Myers, D.S.2    Milne, S.B.3    Ivanova, P.T.4    LaVoie, M.J.5
  • 19
    • 18344393519 scopus 로고    scopus 로고
    • Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples
    • Han X, Gross RW, (2005) Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples. Mass Spectrom Rev 24 (3): 367-412.
    • (2005) Mass Spectrom Rev , vol.24 , Issue.3 , pp. 367-412
    • Han, X.1    Gross, R.W.2
  • 20
    • 33745115631 scopus 로고    scopus 로고
    • Brain tissue lipidomics: Direct probing using matrix-assisted laser desorption/ionization mass spectrometry
    • Woods AS, Jackson SN, (2006) Brain tissue lipidomics: Direct probing using matrix-assisted laser desorption/ionization mass spectrometry. AAPS Journal 8 (2): E391-E395.
    • (2006) AAPS Journal , vol.8 , Issue.2 , pp. 391-395
    • Woods, A.S.1    Jackson, S.N.2
  • 21
    • 84934441481 scopus 로고    scopus 로고
    • Application of lipidomics and metabolomics in the study of adipose tissue
    • Mattila I, Seppänen-Laakso T, Suortti T, Orešič M, (2008) Application of lipidomics and metabolomics in the study of adipose tissue. Meth Mol Biol 456: 123-130.
    • (2008) Meth Mol Biol , vol.456 , pp. 123-130
    • Mattila, I.1    Seppänen-Laakso, T.2    Suortti, T.3    Orešič, M.4
  • 23
    • 42949155123 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase: A novel control point of lipid metabolism and insulin sensitivity
    • Dobrzyn P, Ntambi JM, Dobrzyn A, (2008) Stearoyl-CoA desaturase: A novel control point of lipid metabolism and insulin sensitivity. Eur J Lipid Sci Technol110: 93-100.
    • (2008) Eur J Lipid Sci Technol , vol.110 , pp. 93-100
    • Dobrzyn, P.1    Ntambi, J.M.2    Dobrzyn, A.3
  • 24
    • 0021354540 scopus 로고
    • Oleic acid promotes the activation and translocation of phosphatidate phosphohydrolase from the cytosol to particulate fractions of isolated rat hepatocytes
    • Cascales C, Mangiapane EH, Brindley DN, (1984) Oleic acid promotes the activation and translocation of phosphatidate phosphohydrolase from the cytosol to particulate fractions of isolated rat hepatocytes. Biochem J 219: 911-916.
    • (1984) Biochem J , vol.219 , pp. 911-916
    • Cascales, C.1    Mangiapane, E.H.2    Brindley, D.N.3
  • 25
    • 73149094543 scopus 로고    scopus 로고
    • The plasma lipidomic signature of nonalcoholic steatohepatitis
    • Puri P, Wiest MM, Cheung O, Mirshahi F, Sargeant C, et al. (2009) The plasma lipidomic signature of nonalcoholic steatohepatitis. Hepatology 50: 1827-1838.
    • (2009) Hepatology , vol.50 , pp. 1827-1838
    • Puri, P.1    Wiest, M.M.2    Cheung, O.3    Mirshahi, F.4    Sargeant, C.5
  • 26
    • 39849103404 scopus 로고    scopus 로고
    • Hepatic free fatty acids accumulate in experimental steatohepatitis: Role of adaptive pathways
    • Larter CZ, Yeh MM, Haigh WJ, Williams J, Brown S, al et, (2008) Hepatic free fatty acids accumulate in experimental steatohepatitis: Role of adaptive pathways. J Hepatol 48: 638-647.
    • (2008) J Hepatol , vol.48 , pp. 638-647
    • Larter, C.Z.1    Yeh, M.M.2    Haigh, W.J.3    Williams, J.4    Brown, S.5
  • 27
    • 34848857902 scopus 로고    scopus 로고
    • Metabolomics (liver and blood profiling) in a mouse model in response to fasting: A study of hepatic steatosis
    • van Ginneken V, Verhey E, Poelmann R, Ramakers R, Willems van Dijk K, H, et al. (2007) Metabolomics (liver and blood profiling) in a mouse model in response to fasting: A study of hepatic steatosis. Biochim Biophys Acta 177: 1263-1270.
    • (2007) Biochim Biophys Acta , vol.177 , pp. 1263-1270
    • van Ginneken, V.1    Verhey, E.2    Poelmann, R.3    Ramakers, R.4    Willems van Dijk, K.H.5
  • 28
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: a tale of two "hits"
    • Day CP, James OF, (1998) Steatohepatitis: a tale of two "hits". Gastroenterology 114: 8842-8845.
    • (1998) Gastroenterology , vol.114 , pp. 8842-8845
    • Day, C.P.1    James, O.F.2
  • 30
    • 34347235098 scopus 로고    scopus 로고
    • Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
    • Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, et al. (2007) Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metabol 6: 69-78.
    • (2007) Cell Metabol , vol.6 , pp. 69-78
    • Monetti, M.1    Levin, M.C.2    Watt, M.J.3    Sajan, M.P.4    Marmor, S.5
  • 31
    • 0023927373 scopus 로고
    • Functions of diacylglycerol in glycerolipids metabolism, signal transduction and cellular transformation
    • Bishop WR, Bell RM, (1988) Functions of diacylglycerol in glycerolipids metabolism, signal transduction and cellular transformation. Oncogene Res 2: 205-218.
    • (1988) Oncogene Res , vol.2 , pp. 205-218
    • Bishop, W.R.1    Bell, R.M.2
  • 32
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • Nishizuka Y, (1995) Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 9: 484-496.
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 33
    • 0036500525 scopus 로고    scopus 로고
    • Generation of Diacylglycerol Molecular Species Through Cell Cycle: a role for 1-stearoyl, 2-arachidonyl glycerol in the activation of nuclear protein kinase C-ßII at G2/M
    • Deacon EM, Pettitt TR, Webb P, Cross T, Chahai H, (2002) Generation of Diacylglycerol Molecular Species Through Cell Cycle: a role for 1-stearoyl, 2-arachidonyl glycerol in the activation of nuclear protein kinase C-ßII at G2/M. J Cell Science 115: 983-989.
    • (2002) J Cell Science , vol.115 , pp. 983-989
    • Deacon, E.M.1    Pettitt, T.R.2    Webb, P.3    Cross, T.4    Chahai, H.5
  • 34
    • 68949181550 scopus 로고    scopus 로고
    • Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids
    • Villanueva CJ, Monetti M, Shih M, Zhou, Watkins SM, et al. (2009) Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids. Hepatology 50 (2): 434-442.
    • (2009) Hepatology , vol.50 , Issue.2 , pp. 434-442
    • Villanueva, C.J.1    Monetti, M.2    Shih, M.3    Zhou4    Watkins, S.M.5
  • 35
    • 39549101454 scopus 로고    scopus 로고
    • Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis
    • Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, et al. (2008) Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis. Hepatology 47 (2): 625-635.
    • (2008) Hepatology , vol.47 , Issue.2 , pp. 625-635
    • Yamaguchi, K.1    Yang, L.2    McCall, S.3    Huang, J.4    Yu, X.X.5


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