Lipocalin-2 (NGAL/LCN2), a "help-me" signal in organ inflammation

Hepatology

Volumn 63, Issue 2, 2016, Pages 669-671

  Asimakopoulou, Anastasia ^a   Borkham Kamphorst, Erawan ^a   Tacke, Frank ^a   Weiskirchen, Ralf ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOCALIN; ONCOPROTEIN;

ANIMAL; BACTERIAL INFECTION; BLOOD; LIVER CELL; LIVER REGENERATION; METABOLISM;

ANIMALS; BACTERIAL INFECTIONS; HEPATOCYTES; LIPOCALINS; LIVER REGENERATION; ONCOGENE PROTEINS;

EID: 84956783925     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27930     Document Type: Letter

References (6)

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2. Xu MJ, Feng D, Wu H, Wang H, Chan Y, Kolls J, et al. Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: A critical role for IL-6/STAT3. Hepatology 2015;61:692-702.
3. Borkham-Kamphorst E, van de Leur E, Zimmermann HW, Karlmark KR, Tihaa L, Haas U, et al. Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis. Biochim Biophys Acta 2013;1832:660-673.
4. Borkham-Kamphorst E, Drews F, Weiskirchen R. Induction of lipocalin-2 expression in acute and chronic experimental liver injury moderated by pro-inflammatory cytokines interleukin-1β through nuclear factor-κB activation. Liver Int 2011;31:656-665.
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6. Jha MK, Jeon S, Jin M, Ock J, Kim JH, Lee WH, et al. The pivotal role played by lipocalin-2 in chronic inflammatory pain. Exp Neurol 2014;254:41-53.