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Volumn 56, Issue 20, 2017, Pages 5761-5777

Protease-Sensitive Nanomaterials for Cancer Therapeutics and Imaging

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; NANOSTRUCTURED MATERIALS;

EID: 85020756751     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/acs.iecr.7b00990     Document Type: Review
Times cited : (53)

References (125)
  • 1
    • 84908501841 scopus 로고    scopus 로고
    • Multifunctional, Stimuli-Senstive Nanoparticle Systems for Drug Delivery
    • Torchilin, V. P. Multifunctional, Stimuli-Senstive Nanoparticle Systems for Drug Delivery Nat. Rev. Drug Discovery 2014, 13, 813-827 10.1038/nrd4333
    • (2014) Nat. Rev. Drug Discovery , vol.13 , pp. 813-827
    • Torchilin, V.P.1
  • 3
    • 84864527570 scopus 로고    scopus 로고
    • Enzyme-Responsive Nanoparticles for Drug Release and Diagnostics
    • De La Rica, R.; Aili, D.; Stevens, M. M. Enzyme-Responsive Nanoparticles for Drug Release and Diagnostics Adv. Drug Delivery Rev. 2012, 64, 967-978 10.1016/j.addr.2012.01.002
    • (2012) Adv. Drug Delivery Rev. , vol.64 , pp. 967-978
    • De La Rica, R.1    Aili, D.2    Stevens, M.M.3
  • 4
    • 84908012083 scopus 로고    scopus 로고
    • Enzyme-Responsive Nanomaterials for Controlled Drug Delivery
    • Hu, Q.; Katti, P. S.; Gu, Z. Enzyme-Responsive Nanomaterials for Controlled Drug Delivery Nanoscale 2014, 6, 12273-12286 10.1039/C4NR04249B
    • (2014) Nanoscale , vol.6 , pp. 12273-12286
    • Hu, Q.1    Katti, P.S.2    Gu, Z.3
  • 6
    • 84855236042 scopus 로고    scopus 로고
    • Peptide-Based Molecular Beacons for Cancer Imaging and Therapy
    • Liu, T. W. B.; Chen, J.; Zheng, G. Peptide-Based Molecular Beacons for Cancer Imaging and Therapy Amino Acids 2011, 41, 1123-113 10.1007/s00726-010-0499-1
    • (2011) Amino Acids , vol.41 , pp. 1123-2113
    • Liu, T.W.B.1    Chen, J.2    Zheng, G.3
  • 7
    • 0026522287 scopus 로고
    • The Role of Proteolytic Enzymes in Cancer Invasion and Metastasis
    • Duffy, M. J. The Role of Proteolytic Enzymes in Cancer Invasion and Metastasis Clin. Exp. Metastasis 1992, 10, 145-155 10.1007/BF00132746
    • (1992) Clin. Exp. Metastasis , vol.10 , pp. 145-155
    • Duffy, M.J.1
  • 10
    • 0034993240 scopus 로고    scopus 로고
    • The Enhanced Permeability and Retention (EPR) Effect in Tumor Vasculature: The Key Role of Tumor-Selective Macromolecular Drug Targeting
    • Maeda, H. The Enhanced Permeability and Retention (EPR) Effect in Tumor Vasculature: The Key Role of Tumor-Selective Macromolecular Drug Targeting Adv. Enzyme Regul. 2001, 41, 189-207 10.1016/S0065-2571(00)00013-3
    • (2001) Adv. Enzyme Regul. , vol.41 , pp. 189-207
    • Maeda, H.1
  • 11
    • 84892980829 scopus 로고    scopus 로고
    • A Nanoparticle-Based Strategy for the Imaging of a Broad Range of Tumours by Nonlinear Amplification of Microenvironment Signals
    • Wang, Y.; Zhou, K.; Huang, G.; Hensley, C.; Huang, X.; Ma, X.; Zhao, T.; Sumer, B. D.; Deberardinis, R. J.; Gao, J. A Nanoparticle-Based Strategy for the Imaging of a Broad Range of Tumours by Nonlinear Amplification of Microenvironment Signals Nat. Mater. 2014, 13, 204-212 10.1038/nmat3819
    • (2014) Nat. Mater. , vol.13 , pp. 204-212
    • Wang, Y.1    Zhou, K.2    Huang, G.3    Hensley, C.4    Huang, X.5    Ma, X.6    Zhao, T.7    Sumer, B.D.8    Deberardinis, R.J.9    Gao, J.10
  • 12
    • 79955005399 scopus 로고    scopus 로고
    • Near-Infrared pH-Activatable Fluorescent Probes for Imaging Primary and Metastatic Breast Tumors
    • Lee, H.; Akers, W.; Bhushan, K.; Bloch, S.; Sudlow, G.; Tang, R.; Achilefu, S. Near-Infrared pH-Activatable Fluorescent Probes for Imaging Primary and Metastatic Breast Tumors Bioconjugate Chem. 2011, 22, 777-784 10.1021/bc100584d
    • (2011) Bioconjugate Chem. , vol.22 , pp. 777-784
    • Lee, H.1    Akers, W.2    Bhushan, K.3    Bloch, S.4    Sudlow, G.5    Tang, R.6    Achilefu, S.7
  • 13
    • 84880267293 scopus 로고    scopus 로고
    • Tumor Fibroblast Specific Activation of a Hybrid Ferritin Nanocage-Based Optical Probe for Tumor Microenvironment Imaging
    • Ji, T.; Zhao, Y.; Wang, J.; Zheng, X.; Tian, Y.; Zhao, Y.; Nie, G. Tumor Fibroblast Specific Activation of a Hybrid Ferritin Nanocage-Based Optical Probe for Tumor Microenvironment Imaging Small 2013, 9, 2427-2431 10.1002/smll.201300600
    • (2013) Small , vol.9 , pp. 2427-2431
    • Ji, T.1    Zhao, Y.2    Wang, J.3    Zheng, X.4    Tian, Y.5    Zhao, Y.6    Nie, G.7
  • 15
    • 84874614722 scopus 로고    scopus 로고
    • Supramolecular Nanostructures Formed by Anticancer Drug Assembly
    • Cheetham, A. G.; Zhang, P.; Lin, Y.-A.; Lock, L. L.; Cui, H. Supramolecular Nanostructures Formed by Anticancer Drug Assembly J. Am. Chem. Soc. 2013, 135, 2907-2910 10.1021/ja3115983
    • (2013) J. Am. Chem. Soc. , vol.135 , pp. 2907-2910
    • Cheetham, A.G.1    Zhang, P.2    Lin, Y.-A.3    Lock, L.L.4    Cui, H.5
  • 16
    • 85009761441 scopus 로고    scopus 로고
    • Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment
    • Chen, B.; Dai, W.; He, B.; Zhang, H.; Wang, X.; Wang, Y.; Zhang, Q. Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment Theranostics 2017, 7, 538-558 10.7150/thno.16684
    • (2017) Theranostics , vol.7 , pp. 538-558
    • Chen, B.1    Dai, W.2    He, B.3    Zhang, H.4    Wang, X.5    Wang, Y.6    Zhang, Q.7
  • 17
    • 84907217822 scopus 로고    scopus 로고
    • Stimuli-Responsive Nanomaterials for Therapeutic Protein Delivery
    • Lu, Y.; Sun, W.; Gu, Z. Stimuli-Responsive Nanomaterials for Therapeutic Protein Delivery J. Controlled Release 2014, 194, 1-19 10.1016/j.jconrel.2014.08.015
    • (2014) J. Controlled Release , vol.194 , pp. 1-19
    • Lu, Y.1    Sun, W.2    Gu, Z.3
  • 18
    • 84886292840 scopus 로고    scopus 로고
    • Stimuli-Responsive Nanocarriers for Drug Delivery
    • Mura, S.; Nicolas, J.; Couvreur, P. Stimuli-Responsive Nanocarriers for Drug Delivery Nat. Mater. 2013, 12, 991-1003 10.1038/nmat3776
    • (2013) Nat. Mater. , vol.12 , pp. 991-1003
    • Mura, S.1    Nicolas, J.2    Couvreur, P.3
  • 20
    • 0036125256 scopus 로고    scopus 로고
    • Imaging of Differential Protease Expression in Breast Cancers for Detection of Aggressive Tumor Phenotypes
    • Bremer, C.; Tung, C.-H.; Bogdanov, A.; Weissleder, R. Imaging of Differential Protease Expression in Breast Cancers for Detection of Aggressive Tumor Phenotypes Radiology 2002, 222, 814-818 10.1148/radiol.2223010812
    • (2002) Radiology , vol.222 , pp. 814-818
    • Bremer, C.1    Tung, C.-H.2    Bogdanov, A.3    Weissleder, R.4
  • 22
    • 34548666006 scopus 로고    scopus 로고
    • Noninvasive Optical Imaging of Cysteine Protease Activity Using Fluorescently Quenched Activity-Based Probes
    • Blum, G.; Von Degenfeld, G.; Merchant, M. J.; Blau, H. M.; Bogyo, M. Noninvasive Optical Imaging of Cysteine Protease Activity Using Fluorescently Quenched Activity-Based Probes Nat. Chem. Biol. 2007, 3, 668-677 10.1038/nchembio.2007.26
    • (2007) Nat. Chem. Biol. , vol.3 , pp. 668-677
    • Blum, G.1    Von Degenfeld, G.2    Merchant, M.J.3    Blau, H.M.4    Bogyo, M.5
  • 24
    • 78650424066 scopus 로고    scopus 로고
    • Roles of Matrix Metalloproteinases in Cancer Progression and Their Pharmacological Targeting
    • Gialeli, C.; Theocharis, A. D.; Karamanos, N. K. Roles of Matrix Metalloproteinases in Cancer Progression and Their Pharmacological Targeting FEBS J. 2011, 278, 16-27 10.1111/j.1742-4658.2010.07919.x
    • (2011) FEBS J. , vol.278 , pp. 16-27
    • Gialeli, C.1    Theocharis, A.D.2    Karamanos, N.K.3
  • 25
    • 34248156625 scopus 로고    scopus 로고
    • Matrix Metalloproteases: Underutilized Targets for Drug Delivery
    • Vartak, D. G.; Gemeinhart, R. A. Matrix Metalloproteases: Underutilized Targets for Drug Delivery J. Drug Target. 2007, 15, 1-20 10.1080/10611860600968967
    • (2007) J. Drug Target. , vol.15 , pp. 1-20
    • Vartak, D.G.1    Gemeinhart, R.A.2
  • 26
    • 34648815810 scopus 로고    scopus 로고
    • Emerging Roles of Proteases in Tumour Suppression
    • Lopez-Otin, C.; Matrisian, L. M. Emerging Roles of Proteases in Tumour Suppression Nat. Rev. Cancer 2007, 7, 800-808 10.1038/nrc2228
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 800-808
    • Lopez-Otin, C.1    Matrisian, L.M.2
  • 27
    • 84865513273 scopus 로고    scopus 로고
    • Theranostic Applications of Nanoparticles in Cancer
    • Ahmed, N.; Fessi, H.; Elaissari, A. Theranostic Applications of Nanoparticles in Cancer Drug Discovery Today 2012, 17, 928-934 10.1016/j.drudis.2012.03.010
    • (2012) Drug Discovery Today , vol.17 , pp. 928-934
    • Ahmed, N.1    Fessi, H.2    Elaissari, A.3
  • 28
    • 80054821668 scopus 로고    scopus 로고
    • Theranostics: Combining Imaging and Therapy
    • Kelkar, S. S.; Reineke, T. M. Theranostics: Combining Imaging and Therapy Bioconjugate Chem. 2011, 22, 1879-1903 10.1021/bc200151q
    • (2011) Bioconjugate Chem. , vol.22 , pp. 1879-1903
    • Kelkar, S.S.1    Reineke, T.M.2
  • 29
    • 14144250911 scopus 로고    scopus 로고
    • Recent Advances with Liposomes as Pharmaceutical Carriers
    • Torchilin, V. P. Recent Advances with Liposomes as Pharmaceutical Carriers Nat. Rev. Drug Discovery 2005, 4, 145-160 10.1038/nrd1632
    • (2005) Nat. Rev. Drug Discovery , vol.4 , pp. 145-160
    • Torchilin, V.P.1
  • 30
    • 77949484232 scopus 로고    scopus 로고
    • Dendrimer-Based Nanoparticles for Cancer Therapy
    • Baker, J. R. Dendrimer-Based Nanoparticles for Cancer Therapy Hematology 2009, 14, 708-719 10.1182/asheducation-2009.1.708
    • (2009) Hematology , vol.14 , pp. 708-719
    • Baker, J.R.1
  • 32
    • 17944366258 scopus 로고    scopus 로고
    • Nanostructures in Biodiagnostics
    • Rosi, N. L.; Mirkin, C. A. Nanostructures in Biodiagnostics Chem. Rev. 2005, 105, 1547-1562 10.1021/cr030067f
    • (2005) Chem. Rev. , vol.105 , pp. 1547-1562
    • Rosi, N.L.1    Mirkin, C.A.2
  • 33
    • 84915750322 scopus 로고    scopus 로고
    • Engineered Nanoparticles for Drug Delivery in Cancer Therapy
    • Sun, T.; Zhang, Y. S.; Pang, B.; Hyun, D. C.; Yang, M.; Xia, Y. Engineered Nanoparticles for Drug Delivery in Cancer Therapy Angew. Chemie-Int. Ed. 2014, 53, 12320-12364 10.1002/anie.201403036
    • (2014) Angew. Chemie - Int. Ed. , vol.53 , pp. 12320-12364
    • Sun, T.1    Zhang, Y.S.2    Pang, B.3    Hyun, D.C.4    Yang, M.5    Xia, Y.6
  • 35
    • 63049113732 scopus 로고    scopus 로고
    • Molecular Hydrogels of Therapeutic Agents
    • Zhao, F.; Lung Ma, M.; Xu, B. Molecular Hydrogels of Therapeutic Agents Chem. Soc. Rev. 2009, 38, 883-891 10.1039/B806410P
    • (2009) Chem. Soc. Rev. , vol.38 , pp. 883-891
    • Zhao, F.1    Lung Ma, M.2    Xu, B.3
  • 36
    • 39049157239 scopus 로고    scopus 로고
    • Incorporation of a Matrix Metalloproteinase-Sensitive Substrate into Self-Assembling Peptides - A Model for Biofunctional Scaffolds
    • Chau, Y.; Luo, Y.; Cheung, A. C. Y.; Nagai, Y.; Zhang, S.; Kobler, J. B.; Zeitels, S. M.; Langer, R. Incorporation of a Matrix Metalloproteinase-Sensitive Substrate into Self-Assembling Peptides-A Model for Biofunctional Scaffolds Biomaterials 2008, 29, 1713-1719 10.1016/j.biomaterials.2007.11.046
    • (2008) Biomaterials , vol.29 , pp. 1713-1719
    • Chau, Y.1    Luo, Y.2    Cheung, A.C.Y.3    Nagai, Y.4    Zhang, S.5    Kobler, J.B.6    Zeitels, S.M.7    Langer, R.8
  • 37
    • 49449119098 scopus 로고    scopus 로고
    • Antibody-Drug Conjugates for Cancer Therapy
    • Carter, P. J.; Senter, P. D. Antibody-Drug Conjugates for Cancer Therapy Cancer J. 2008, 14, 154-169 10.1097/PPO.0b013e318172d704
    • (2008) Cancer J. , vol.14 , pp. 154-169
    • Carter, P.J.1    Senter, P.D.2
  • 42
    • 84863338346 scopus 로고    scopus 로고
    • Multifunctional Nanoparticles for Multimodal Imaging and Theragnosis
    • Lee, D.-E.; Koo, H.; Sun, I.-C.; Hee Ryu, J.; Kim, K.; Chan Kwon, I. Multifunctional Nanoparticles for Multimodal Imaging and Theragnosis Chem. Soc. Rev. 2012, 41, 2656-2672 10.1039/c2cs15261d
    • (2012) Chem. Soc. Rev. , vol.41 , pp. 2656-2672
    • Lee, D.-E.1    Koo, H.2    Sun, I.-C.3    Hee Ryu, J.4    Kim, K.5    Chan Kwon, I.6
  • 43
    • 34248402413 scopus 로고    scopus 로고
    • Shape Effects of Filaments versus Spherical Particles in Flow and Drug Delivery
    • Geng, Y.; Dalhaimer, P.; Cai, S.; Tsai, R.; Tewari, M.; Minko, T.; Discher, D. E. Shape Effects of Filaments versus Spherical Particles in Flow and Drug Delivery Nat. Nanotechnol. 2007, 2, 249-255 10.1038/nnano.2007.70
    • (2007) Nat. Nanotechnol. , vol.2 , pp. 249-255
    • Geng, Y.1    Dalhaimer, P.2    Cai, S.3    Tsai, R.4    Tewari, M.5    Minko, T.6    Discher, D.E.7
  • 44
    • 84977829947 scopus 로고    scopus 로고
    • Building Nanostructures with Drugs
    • Ma, W.; Cheetham, A. G.; Cui, H. Building Nanostructures with Drugs Nano Today 2015, 11, 13-30 10.1016/j.nantod.2015.11.003
    • (2015) Nano Today , vol.11 , pp. 13-30
    • Ma, W.1    Cheetham, A.G.2    Cui, H.3
  • 45
    • 84876706291 scopus 로고    scopus 로고
    • A Short Circulating Peptide Nanofiber as a Carrier for Tumoral Delivery
    • Wagh, A.; Singh, J.; Qian, S.; Law, B. A Short Circulating Peptide Nanofiber as a Carrier for Tumoral Delivery Nanomedicine 2013, 9, 449-457 10.1016/j.nano.2012.10.009
    • (2013) Nanomedicine , vol.9 , pp. 449-457
    • Wagh, A.1    Singh, J.2    Qian, S.3    Law, B.4
  • 46
    • 84863666971 scopus 로고    scopus 로고
    • Targeting Strategies for Multifunctional Nanoparticles in Cancer Imaging and Therapy
    • Yu, M. K.; Park, J.; Jon, S.; Sangyong, J. Targeting Strategies for Multifunctional Nanoparticles in Cancer Imaging and Therapy Theranostics 2012, 2, 3-44 10.7150/thno.3463
    • (2012) Theranostics , vol.2 , pp. 3-44
    • Yu, M.K.1    Park, J.2    Jon, S.3    Sangyong, J.4
  • 47
    • 84947252300 scopus 로고    scopus 로고
    • One-Component Nanomedicine
    • Su, H.; Koo, J. M.; Cui, H. One-Component Nanomedicine J. Controlled Release 2015, 219, 383-395 10.1016/j.jconrel.2015.09.056
    • (2015) J. Controlled Release , vol.219 , pp. 383-395
    • Su, H.1    Koo, J.M.2    Cui, H.3
  • 48
    • 84866127509 scopus 로고    scopus 로고
    • Imaging Enzyme-Triggered Self-Assembly of Small Molecules inside Live Cells
    • Gao, Y.; Shi, J.; Yuan, D.; Xu, B. Imaging Enzyme-Triggered Self-Assembly of Small Molecules inside Live Cells Nat. Commun. 2012, 1, 1033-1038 10.1038/ncomms2040
    • (2012) Nat. Commun. , vol.1 , pp. 1033-1038
    • Gao, Y.1    Shi, J.2    Yuan, D.3    Xu, B.4
  • 49
    • 79959420942 scopus 로고    scopus 로고
    • Strategies for in Vivo Imaging of Enzyme Activity: An Overview and Recent Advances
    • Razgulin, A.; Ma, N.; Rao, J. Strategies for in Vivo Imaging of Enzyme Activity: An Overview and Recent Advances Chem. Soc. Rev. 2011, 40, 4186-4216 10.1039/c1cs15035a
    • (2011) Chem. Soc. Rev. , vol.40 , pp. 4186-4216
    • Razgulin, A.1    Ma, N.2    Rao, J.3
  • 50
    • 84894266026 scopus 로고    scopus 로고
    • Environment-Sensitive Fluorescent Supramolecular Nanofibers for Imaging Applications
    • Cai, Y.; Shi, Y.; Wang, H.; Wang, J.; Ding, D.; Wang, L.; Yang, Z. Environment-Sensitive Fluorescent Supramolecular Nanofibers for Imaging Applications Anal. Chem. 2014, 86, 2193-2199 10.1021/ac4038653
    • (2014) Anal. Chem. , vol.86 , pp. 2193-2199
    • Cai, Y.1    Shi, Y.2    Wang, H.3    Wang, J.4    Ding, D.5    Wang, L.6    Yang, Z.7
  • 51
    • 0034283034 scopus 로고    scopus 로고
    • In Vivo Imaging of Proteolytic Enzyme Activity Using a Novel Molecular Reporter in Vivo Imaging of Proteolytic Enzyme Activity Using a Novel Molecular Reporter 1
    • Tung, C.; Mahmood, U.; Bredow, S.; Weissleder, R. In Vivo Imaging of Proteolytic Enzyme Activity Using a Novel Molecular Reporter In Vivo Imaging of Proteolytic Enzyme Activity Using a Novel Molecular Reporter 1 Cancer Res. 2000, 60, 4953-4958
    • (2000) Cancer Res. , vol.60 , pp. 4953-4958
    • Tung, C.1    Mahmood, U.2    Bredow, S.3    Weissleder, R.4
  • 52
    • 0032951071 scopus 로고    scopus 로고
    • In Vivo Imaging of Tumors with Protease-Activated near-Infrared Fluorescent Probes
    • Weissleder, R.; Tung, C.-H.; Mahmood, U.; Bogdanov, A. In Vivo Imaging of Tumors with Protease-Activated near-Infrared Fluorescent Probes Nat. Biotechnol. 1999, 17, 375-378 10.1038/7933
    • (1999) Nat. Biotechnol. , vol.17 , pp. 375-378
    • Weissleder, R.1    Tung, C.-H.2    Mahmood, U.3    Bogdanov, A.4
  • 53
    • 41649110649 scopus 로고    scopus 로고
    • Imaging in the Era of Molecular Oncology
    • Weissleder, R.; Pittet, M. J. Imaging in the Era of Molecular Oncology Nature 2008, 452, 580-589 10.1038/nature06917
    • (2008) Nature , vol.452 , pp. 580-589
    • Weissleder, R.1    Pittet, M.J.2
  • 55
  • 56
    • 84930060715 scopus 로고    scopus 로고
    • Design and Assembly of Supramolecular Dual-Modality Nanoprobes
    • Liu, S.; Zhang, P.; Banerjee, S. R.; Xu, J.; Pomper, M. G.; Cui, H. Design and Assembly of Supramolecular Dual-Modality Nanoprobes Nanoscale 2015, 7, 9462-9466 10.1039/C5NR01518A
    • (2015) Nanoscale , vol.7 , pp. 9462-9466
    • Liu, S.1    Zhang, P.2    Banerjee, S.R.3    Xu, J.4    Pomper, M.G.5    Cui, H.6
  • 57
    • 84867643331 scopus 로고    scopus 로고
    • Tumor-Trageting Multi-Functional Nanoparticles for Theragnosis: New Paradigm for Cancer Therapy
    • Ryu, J. H.; Koo, H.; Sun, I.-C.; Yuk, S. H.; Choi, K.; Kim, K.; Kwon, I. C. Tumor-Trageting Multi-Functional Nanoparticles for Theragnosis: New Paradigm for Cancer Therapy Adv. Drug Delivery Rev. 2012, 64, 1447-1458 10.1016/j.addr.2012.06.012
    • (2012) Adv. Drug Delivery Rev. , vol.64 , pp. 1447-1458
    • Ryu, J.H.1    Koo, H.2    Sun, I.-C.3    Yuk, S.H.4    Choi, K.5    Kim, K.6    Kwon, I.C.7
  • 58
    • 84869103855 scopus 로고    scopus 로고
    • Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities
    • Cheng, Z.; Al Zaki, A.; Hui, J. Z.; Muzykantov, V. R.; Tsourkas, A. Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities Science 2012, 338, 903-910 10.1126/science.1226338
    • (2012) Science , vol.338 , pp. 903-910
    • Cheng, Z.1    Al Zaki, A.2    Hui, J.Z.3    Muzykantov, V.R.4    Tsourkas, A.5
  • 59
    • 78649330634 scopus 로고    scopus 로고
    • Imaging and Drug Delivery Using Theranostic Nanoparticles
    • Janib, S. M.; Moses, A. S.; Mackay, J. A. Imaging and Drug Delivery Using Theranostic Nanoparticles Adv. Drug Delivery Rev. 2010, 62, 1052-1063 10.1016/j.addr.2010.08.004
    • (2010) Adv. Drug Delivery Rev. , vol.62 , pp. 1052-1063
    • Janib, S.M.1    Moses, A.S.2    Mackay, J.A.3
  • 61
    • 84862641306 scopus 로고    scopus 로고
    • Image Guided Therapy: The Advent of Theranostic Agents
    • Terreno, E.; Uggeri, F.; Aime, S. Image Guided Therapy: The Advent of Theranostic Agents J. Controlled Release 2012, 161, 328-337 10.1016/j.jconrel.2012.05.028
    • (2012) J. Controlled Release , vol.161 , pp. 328-337
    • Terreno, E.1    Uggeri, F.2    Aime, S.3
  • 62
    • 84867627449 scopus 로고    scopus 로고
    • Nanotheranostics for Personalized Medicine
    • Mura, S.; Couvreur, P. Nanotheranostics for Personalized Medicine Adv. Drug Delivery Rev. 2012, 64, 1394-1416 10.1016/j.addr.2012.06.006
    • (2012) Adv. Drug Delivery Rev. , vol.64 , pp. 1394-1416
    • Mura, S.1    Couvreur, P.2
  • 63
    • 84899056215 scopus 로고    scopus 로고
    • Gel-Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy
    • Jiang, T.; Mo, R.; Bellotti, A.; Zhou, J.; Gu, Z. Gel-Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy Adv. Funct. Mater. 2014, 24, 2295-2304 10.1002/adfm.201303222
    • (2014) Adv. Funct. Mater. , vol.24 , pp. 2295-2304
    • Jiang, T.1    Mo, R.2    Bellotti, A.3    Zhou, J.4    Gu, Z.5
  • 64
    • 84920989615 scopus 로고    scopus 로고
    • Nanotechnology
    • Langer, R.; Weissleder, R. Nanotechnology JAMA 2015, 313, 135-136 10.1001/jama.2014.16315
    • (2015) JAMA , vol.313 , pp. 135-136
    • Langer, R.1    Weissleder, R.2
  • 65
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and Biodistribution of Nanoparticles
    • Li, S.-D.; Huang, L. Pharmacokinetics and Biodistribution of Nanoparticles Mol. Pharmaceutics 2008, 5, 496-504 10.1021/mp800049w
    • (2008) Mol. Pharmaceutics , vol.5 , pp. 496-504
    • Li, S.-D.1    Huang, L.2
  • 67
    • 84906951200 scopus 로고    scopus 로고
    • Controlled Release of Free Doxorubicin from Peptide-drug Conjugates by Drug Loading
    • Chen, Z.; Zhang, P.; Cheetham, A. G.; Moon, J. H.; Moxley, J. W.; Lin, Y.-A.; Cui, H. Controlled Release of Free Doxorubicin from Peptide-drug Conjugates by Drug Loading J. Controlled Release 2014, 191, 123-130 10.1016/j.jconrel.2014.05.051
    • (2014) J. Controlled Release , vol.191 , pp. 123-130
    • Chen, Z.1    Zhang, P.2    Cheetham, A.G.3    Moon, J.H.4    Moxley, J.W.5    Lin, Y.-A.6    Cui, H.7
  • 69
    • 84885716472 scopus 로고    scopus 로고
    • Enhanced Anticancer Activity of Nanopreparation Containing an MMP2-Sensitive PEG-Drug Conjugate and Cell-Penetrating Moiety
    • Zhu, L.; Wang, T.; Perche, F.; Taigind, A.; Torchilin, V. P. Enhanced Anticancer Activity of Nanopreparation Containing an MMP2-Sensitive PEG-Drug Conjugate and Cell-Penetrating Moiety Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 17047-17052 10.1073/pnas.1304987110
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 17047-17052
    • Zhu, L.1    Wang, T.2    Perche, F.3    Taigind, A.4    Torchilin, V.P.5
  • 70
    • 0030788411 scopus 로고    scopus 로고
    • The Urokinasetype Plasminogen Activator System in Cancer Metastasis
    • Andreasen, P. A.; Kjoller, L.; Christensen, L.; Duffy, M. J. The Urokinasetype Plasminogen Activator System in Cancer Metastasis Int. J. Cancer 1997, 72, 1-22 10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z
    • (1997) Int. J. Cancer , vol.72 , pp. 1-22
    • Andreasen, P.A.1    Kjoller, L.2    Christensen, L.3    Duffy, M.J.4
  • 71
    • 79952982287 scopus 로고    scopus 로고
    • Protease-Sensitive, Polymer-Caged Liposomes: A Method for Making Highly Targeted Liposomes Using Triggered Release
    • Basel, M. T.; Shrestha, T. B.; Troyer, D. L.; Bossmann, S. H. Protease-Sensitive, Polymer-Caged Liposomes: A Method for Making Highly Targeted Liposomes Using Triggered Release ACS Nano 2011, 5, 2162-2175 10.1021/nn103362n
    • (2011) ACS Nano , vol.5 , pp. 2162-2175
    • Basel, M.T.1    Shrestha, T.B.2    Troyer, D.L.3    Bossmann, S.H.4
  • 73
    • 84877040295 scopus 로고    scopus 로고
    • Tumor Targeting and Microenvironment-Responsive Nanoparticles for Gene Delivery
    • Huang, S.; Shao, K.; Kuang, Y.; Liu, Y.; Li, J.; An, S.; Guo, Y.; Ma, H.; He, X.; Jiang, C. Tumor Targeting and Microenvironment-Responsive Nanoparticles for Gene Delivery Biomaterials 2013, 34, 5294-5302 10.1016/j.biomaterials.2013.03.043
    • (2013) Biomaterials , vol.34 , pp. 5294-5302
    • Huang, S.1    Shao, K.2    Kuang, Y.3    Liu, Y.4    Li, J.5    An, S.6    Guo, Y.7    Ma, H.8    He, X.9    Jiang, C.10
  • 75
    • 84921511395 scopus 로고    scopus 로고
    • Cancer Cell Death Induced by the Intracellular Self-Assembly of an Enzyme-Responsive Supramolecular Gelator
    • Tanaka, A.; Fukuoka, Y.; Morimoto, Y.; Honjo, T.; Koda, D.; Goto, M.; Maruyama, T. Cancer Cell Death Induced by the Intracellular Self-Assembly of an Enzyme-Responsive Supramolecular Gelator J. Am. Chem. Soc. 2015, 137, 770-775 10.1021/ja510156v
    • (2015) J. Am. Chem. Soc. , vol.137 , pp. 770-775
    • Tanaka, A.1    Fukuoka, Y.2    Morimoto, Y.3    Honjo, T.4    Koda, D.5    Goto, M.6    Maruyama, T.7
  • 76
    • 19444371972 scopus 로고    scopus 로고
    • Enzymatic Formation of Supramolecular Hydrogels
    • Yang, B. Z.; Gu, H.; Fu, D.; Gao, P.; Lam, J. K.; Xu, B. Enzymatic Formation of Supramolecular Hydrogels Adv. Mater. 2004, 16, 1440-1444 10.1002/adma.200400340
    • (2004) Adv. Mater. , vol.16 , pp. 1440-1444
    • Yang, B.Z.1    Gu, H.2    Fu, D.3    Gao, P.4    Lam, J.K.5    Xu, B.6
  • 77
    • 70349756884 scopus 로고    scopus 로고
    • Enzyme-Instructed Molecular Self-Assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative
    • Gao, Y.; Kuang, Y.; Guo, Z.-F.; Guo, Z.; Krauss, I. J.; Xu, B. Enzyme-Instructed Molecular Self-Assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative J. Am. Chem. Soc. 2009, 131, 13576-13577 10.1021/ja904411z
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 13576-13577
    • Gao, Y.1    Kuang, Y.2    Guo, Z.-F.3    Guo, Z.4    Krauss, I.J.5    Xu, B.6
  • 78
    • 84962109822 scopus 로고    scopus 로고
    • Enzyme-Instructed Self-Assembly of Small D-Peptides as a Multiple- Step Process for Selectively Killing Cancer Cells
    • Zhou, J.; Du, X.; Yamagata, N.; Xu, B. Enzyme-Instructed Self-Assembly of Small D-Peptides as a Multiple- Step Process for Selectively Killing Cancer Cells J. Am. Chem. Soc. 2016, 138, 3813-3823 10.1021/jacs.5b13541
    • (2016) J. Am. Chem. Soc. , vol.138 , pp. 3813-3823
    • Zhou, J.1    Du, X.2    Yamagata, N.3    Xu, B.4
  • 79
    • 85006085688 scopus 로고    scopus 로고
    • Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance
    • Wang, H.; Feng, Z.; Wang, Y.; Zhou, R.; Yang, Z.; Xu, B. Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance J. Am. Chem. Soc. 2016, 138, 16046-16055 10.1021/jacs.6b09783
    • (2016) J. Am. Chem. Soc. , vol.138 , pp. 16046-16055
    • Wang, H.1    Feng, Z.2    Wang, Y.3    Zhou, R.4    Yang, Z.5    Xu, B.6
  • 81
    • 84966713472 scopus 로고    scopus 로고
    • MMP-9 Triggered Self-Assembly of Doxorubicin Nanofiber Depots Halts Tumor Growth
    • Kalafatovic, D.; Nobis, M.; Son, J.; Anderson, K. I.; Ulijn, R. V. MMP-9 Triggered Self-Assembly of Doxorubicin Nanofiber Depots Halts Tumor Growth Biomaterials 2016, 98, 192-202 10.1016/j.biomaterials.2016.04.039
    • (2016) Biomaterials , vol.98 , pp. 192-202
    • Kalafatovic, D.1    Nobis, M.2    Son, J.3    Anderson, K.I.4    Ulijn, R.V.5
  • 82
    • 0033200238 scopus 로고    scopus 로고
    • Preparation of a Cathepsin D Sensitive Near-Infrared Fluorescence Probe for Imaging
    • Tung, C.-H.; Bredow, S.; Mahmood, U.; Weissleder, R. Preparation of a Cathepsin D Sensitive Near-Infrared Fluorescence Probe for Imaging Bioconjugate Chem. 1999, 10, 892-896 10.1021/bc990052h
    • (1999) Bioconjugate Chem. , vol.10 , pp. 892-896
    • Tung, C.-H.1    Bredow, S.2    Mahmood, U.3    Weissleder, R.4
  • 85
    • 84906872153 scopus 로고    scopus 로고
    • Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology
    • Chi, C.; Du, Y.; Ye, J.; Kou, D.; Qiu, J.; Wang, J.; Tian, J.; Chen, X. Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology Theranostics 2014, 4, 1072-1084 10.7150/thno.9899
    • (2014) Theranostics , vol.4 , pp. 1072-1084
    • Chi, C.1    Du, Y.2    Ye, J.3    Kou, D.4    Qiu, J.5    Wang, J.6    Tian, J.7    Chen, X.8
  • 87
    • 42249084437 scopus 로고    scopus 로고
    • A Near-Infrared-Fluorescence-Quenched Gold-Nanoparticle Imaging Probe for in Vivo Drug Screening and Protease Activity Determination
    • Lee, S.; Cha, E.-J.; Park, K.; Lee, S.-Y.; Hong, J.-K.; Sun, I.-C.; Kim, S. Y.; Choi, K.; Kwon, I. C.; Kim, K.; Ahn, C.-H. A Near-Infrared-Fluorescence-Quenched Gold-Nanoparticle Imaging Probe for In Vivo Drug Screening and Protease Activity Determination Angew. Chem. 2008, 120, 2846-2849 10.1002/ange.200705240
    • (2008) Angew. Chem. , vol.120 , pp. 2846-2849
    • Lee, S.1    Cha, E.-J.2    Park, K.3    Lee, S.-Y.4    Hong, J.-K.5    Sun, I.-C.6    Kim, S.Y.7    Choi, K.8    Kwon, I.C.9    Kim, K.10    Ahn, C.-H.11
  • 89
    • 84893574648 scopus 로고    scopus 로고
    • Visualization of Protease Activity in Vivo Using an Activatable Photo-Acoustic Imaging Probe Based on CuS Nanoparticles
    • Yang, K.; Zhu, L.; Nie, L.; Sun, X.; Cheng, L.; Wu, C.; Niu, G.; Chen, X.; Liu, Z. Visualization of Protease Activity In Vivo Using an Activatable Photo-Acoustic Imaging Probe Based on CuS Nanoparticles Theranostics 2014, 4, 134-141 10.7150/thno.7217
    • (2014) Theranostics , vol.4 , pp. 134-141
    • Yang, K.1    Zhu, L.2    Nie, L.3    Sun, X.4    Cheng, L.5    Wu, C.6    Niu, G.7    Chen, X.8    Liu, Z.9
  • 91
    • 50449092432 scopus 로고    scopus 로고
    • Overcoming Multidrug Resistance of Small-Molecule Therapeutics through Conjugation with Releasable Octaarginine Transporters
    • Dubikovskaya, E. A.; Thorne, S. H.; Pillow, T. H.; Contag, C. H.; Wender, P. A. Overcoming Multidrug Resistance of Small-Molecule Therapeutics through Conjugation with Releasable Octaarginine Transporters Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 12128-12133 10.1073/pnas.0805374105
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 12128-12133
    • Dubikovskaya, E.A.1    Thorne, S.H.2    Pillow, T.H.3    Contag, C.H.4    Wender, P.A.5
  • 92
    • 79958189858 scopus 로고    scopus 로고
    • Nanomedicine for Targeted Cancer Therapy: Towards the Overcoming of Drug Resistance
    • Shapira, A.; Livney, Y. D.; Broxterman, H. J.; Assaraf, Y. G. Nanomedicine for Targeted Cancer Therapy: Towards the Overcoming of Drug Resistance Drug Resist. Updates 2011, 14, 150-163 10.1016/j.drup.2011.01.003
    • (2011) Drug Resist. Updates , vol.14 , pp. 150-163
    • Shapira, A.1    Livney, Y.D.2    Broxterman, H.J.3    Assaraf, Y.G.4
  • 93
  • 94
    • 77749297971 scopus 로고    scopus 로고
    • Activatable Cell Penetrating Peptides Linked to Nanoparticles as Dual Probes for in Vivo Fluorescence and MR Imaging of Proteases
    • Olson, E. S.; Jiang, T.; Aguilera, T. A.; Nguyen, Q. T.; Ellies, L. G.; Scadeng, M.; Tsien, R. Y. Activatable Cell Penetrating Peptides Linked to Nanoparticles as Dual Probes for in Vivo Fluorescence and MR Imaging of Proteases Proc. Natl. Acad. Sci. U. S. A. 2010, 107, 4311-4316 10.1073/pnas.0910283107
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 4311-4316
    • Olson, E.S.1    Jiang, T.2    Aguilera, T.A.3    Nguyen, Q.T.4    Ellies, L.G.5    Scadeng, M.6    Tsien, R.Y.7
  • 97
    • 84902655584 scopus 로고    scopus 로고
    • Dual Targeting of Integrin a v B 3 and Matrix Metalloproteinase- 2 for Optical Imaging of Tumors and Chemotherapeutic Delivery
    • Crisp, J. L.; Savariar, E. N.; Glasgow, H. L.; Ellies, L. G.; Whitney, M. A.; Tsien, R. Y. Dual Targeting of Integrin a v B 3 and Matrix Metalloproteinase- 2 for Optical Imaging of Tumors and Chemotherapeutic Delivery Mol. Cancer Ther. 2014, 13, 1514-1525 10.1158/1535-7163.MCT-13-1067
    • (2014) Mol. Cancer Ther. , vol.13 , pp. 1514-1525
    • Crisp, J.L.1    Savariar, E.N.2    Glasgow, H.L.3    Ellies, L.G.4    Whitney, M.A.5    Tsien, R.Y.6
  • 100
    • 84879645526 scopus 로고    scopus 로고
    • Design and Construction of Supramolecular Nanobeacons for Enzyme Detection
    • Lock, L. L.; Cheetham, A. G.; Zhang, P.; Cui, H. Design and Construction of Supramolecular Nanobeacons for Enzyme Detection ACS Nano 2013, 7, 4924-4932 10.1021/nn400218a
    • (2013) ACS Nano , vol.7 , pp. 4924-4932
    • Lock, L.L.1    Cheetham, A.G.2    Zhang, P.3    Cui, H.4
  • 101
    • 84961275913 scopus 로고    scopus 로고
    • Tuning Cellular Uptake of Molecular Probes by Rational Design of Their Assembly into Supramolecular Nanoprobes
    • Lock, L. L.; Reyes, C. D.; Zhang, P.; Cui, H. Tuning Cellular Uptake of Molecular Probes by Rational Design of Their Assembly into Supramolecular Nanoprobes J. Am. Chem. Soc. 2016, 138, 3533-3540 10.1021/jacs.6b00073
    • (2016) J. Am. Chem. Soc. , vol.138 , pp. 3533-3540
    • Lock, L.L.1    Reyes, C.D.2    Zhang, P.3    Cui, H.4
  • 103
    • 36849043984 scopus 로고    scopus 로고
    • Protease-Sensitive Fluorescent Nanofibers
    • Law, B.; Weissleder, R.; Tung, C.-H. Protease-Sensitive Fluorescent Nanofibers Bioconjugate Chem. 2007, 18, 1701-1704 10.1021/bc070054z
    • (2007) Bioconjugate Chem. , vol.18 , pp. 1701-1704
    • Law, B.1    Weissleder, R.2    Tung, C.-H.3
  • 104
    • 79952443388 scopus 로고    scopus 로고
    • Design and Synthesis of a near-Infrared Fluorescent Nanofiber Precursor for Detecting Cell-Secreted Urokinase Activity
    • Malik, R.; Qian, S.; Law, B. Design and Synthesis of a near-Infrared Fluorescent Nanofiber Precursor for Detecting Cell-Secreted Urokinase Activity Anal. Biochem. 2011, 412, 26-33 10.1016/j.ab.2011.01.010
    • (2011) Anal. Biochem. , vol.412 , pp. 26-33
    • Malik, R.1    Qian, S.2    Law, B.3
  • 105
    • 84856145410 scopus 로고    scopus 로고
    • Multiplex Sensing of Protease and Kinase Enzyme Activity via Orthogonal Coupling of Quantum Dot-Peptide Conjugates
    • Lowe, S. B.; Dick, J. A. G.; Cohen, B. E.; Stevens, M. M. Multiplex Sensing of Protease and Kinase Enzyme Activity via Orthogonal Coupling of Quantum Dot-Peptide Conjugates ACS Nano 2012, 6, 851-857 10.1021/nn204361s
    • (2012) ACS Nano , vol.6 , pp. 851-857
    • Lowe, S.B.1    Dick, J.A.G.2    Cohen, B.E.3    Stevens, M.M.4
  • 106
    • 84901351258 scopus 로고    scopus 로고
    • Bioorthogonal Cyclization-Mediated in Situ Self-Assembly of Small-Molecule Probes for Imaging Caspase Activity in Vivo
    • Ye, D.; Shuhendler, A. J.; Cui, L.; Tong, L.; Tee, S. S.; Tikhomirov, G.; Felsher, D. W.; Rao, J. Bioorthogonal Cyclization-Mediated in Situ Self-Assembly of Small-Molecule Probes for Imaging Caspase Activity in Vivo Nat. Chem. 2014, 6, 519-526 10.1038/nchem.1920
    • (2014) Nat. Chem. , vol.6 , pp. 519-526
    • Ye, D.1    Shuhendler, A.J.2    Cui, L.3    Tong, L.4    Tee, S.S.5    Tikhomirov, G.6    Felsher, D.W.7    Rao, J.8
  • 107
    • 84906333033 scopus 로고    scopus 로고
    • Caspase-Responsive Smart Gadolinium-Based Contrast Agent for Magnetic Resonance Imaging of Drug-Induced Apoptosis
    • Ye, D.; Shuhendler, A. J.; Pandit, P.; Brewer, K. D.; Tee, S. S.; Cui, L.; Tikhomirov, G.; Rutt, B.; Rao, J. Caspase-Responsive Smart Gadolinium-Based Contrast Agent for Magnetic Resonance Imaging of Drug-Induced Apoptosis Chem. Sci. 2014, 5, 3845-3852 10.1039/C4SC01392A
    • (2014) Chem. Sci. , vol.5 , pp. 3845-3852
    • Ye, D.1    Shuhendler, A.J.2    Pandit, P.3    Brewer, K.D.4    Tee, S.S.5    Cui, L.6    Tikhomirov, G.7    Rutt, B.8    Rao, J.9
  • 108
    • 84940975746 scopus 로고    scopus 로고
    • Preclinical Kinetic Analysis of the Caspase-3/7 PET Tracer 18F-C-SNAT: Quantifying the Changes in Blood Flow and Tumor Retention after Chemotherapy
    • Palner, M.; Shen, B.; Jeon, J.; Lin, J.; Chin, F. T.; Rao, J. Preclinical Kinetic Analysis of the Caspase-3/7 PET Tracer 18F-C-SNAT: Quantifying the Changes in Blood Flow and Tumor Retention After Chemotherapy J. Nucl. Med. 2015, 56, 1415-1421 10.2967/jnumed.115.155259
    • (2015) J. Nucl. Med. , vol.56 , pp. 1415-1421
    • Palner, M.1    Shen, B.2    Jeon, J.3    Lin, J.4    Chin, F.T.5    Rao, J.6
  • 109
    • 84942931457 scopus 로고    scopus 로고
    • A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment
    • Witney, T. H.; Hoehne, A.; Reeves, R. E.; Ilovich, O.; Namavari, M.; Shen, B.; Chin, F. T.; Rao, J.; Gambhir, S. S. A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment Clin. Cancer Res. 2015, 21, 3896-3905 10.1158/1078-0432.CCR-14-3176
    • (2015) Clin. Cancer Res. , vol.21 , pp. 3896-3905
    • Witney, T.H.1    Hoehne, A.2    Reeves, R.E.3    Ilovich, O.4    Namavari, M.5    Shen, B.6    Chin, F.T.7    Rao, J.8    Gambhir, S.S.9
  • 111
    • 84874952603 scopus 로고    scopus 로고
    • Chemotherapeutic Drug Delivery to Cancer Cells Using a Combination of Folate Targeting and Tumor Microenvironment-Sensitive Polypeptides
    • Gao, W.; Xiang, B.; Meng, T.; Liu, F.; Qi, X. Chemotherapeutic Drug Delivery to Cancer Cells Using a Combination of Folate Targeting and Tumor Microenvironment-Sensitive Polypeptides Biomaterials 2013, 34, 4137-4149 10.1016/j.biomaterials.2013.02.014
    • (2013) Biomaterials , vol.34 , pp. 4137-4149
    • Gao, W.1    Xiang, B.2    Meng, T.3    Liu, F.4    Qi, X.5
  • 112
    • 84940186937 scopus 로고    scopus 로고
    • Enzyme Sensitive, Surface Engineered Nanoparticles for Enhanced Delivery of Camptothecin
    • Yu, H.; Chen, J.; Liu, S.; Lu, Q.; He, J.; Zhou, Z.; Hu, Y. Enzyme Sensitive, Surface Engineered Nanoparticles for Enhanced Delivery of Camptothecin J. Controlled Release 2015, 216, 111-120 10.1016/j.jconrel.2015.08.021
    • (2015) J. Controlled Release , vol.216 , pp. 111-120
    • Yu, H.1    Chen, J.2    Liu, S.3    Lu, Q.4    He, J.5    Zhou, Z.6    Hu, Y.7
  • 113
    • 84930450037 scopus 로고    scopus 로고
    • Matrix Metalloproteinase-Sensitive Size-Shrinkable Nanoparticles for Deep Tumor Penetration and pH Triggered Doxorubicin Release
    • Ruan, S.; Cao, X.; Cun, X.; Hu, G.; Zhou, Y.; Zhang, Y.; Lu, L.; He, Q.; Gao, H. Matrix Metalloproteinase-Sensitive Size-Shrinkable Nanoparticles for Deep Tumor Penetration and pH Triggered Doxorubicin Release Biomaterials 2015, 60, 100-110 10.1016/j.biomaterials.2015.05.006
    • (2015) Biomaterials , vol.60 , pp. 100-110
    • Ruan, S.1    Cao, X.2    Cun, X.3    Hu, G.4    Zhou, Y.5    Zhang, Y.6    Lu, L.7    He, Q.8    Gao, H.9
  • 114
    • 84937403703 scopus 로고    scopus 로고
    • A Smart Polymeric Platform for Multistage Nucleus-Targeted Anticancer Drug Delivery
    • Zhong, J.; Li, L.; Zhu, X.; Guan, S.; Yang, Q.; Zhou, Z.; Zhang, Z.; Huang, Y. A Smart Polymeric Platform for Multistage Nucleus-Targeted Anticancer Drug Delivery Biomaterials 2015, 65, 43-55 10.1016/j.biomaterials.2015.06.042
    • (2015) Biomaterials , vol.65 , pp. 43-55
    • Zhong, J.1    Li, L.2    Zhu, X.3    Guan, S.4    Yang, Q.5    Zhou, Z.6    Zhang, Z.7    Huang, Y.8
  • 116
    • 33745648315 scopus 로고    scopus 로고
    • Photodynamic Therapy Agent with a Built-In Apoptosis Sensor for Evaluating Its Own Therapeutic Outcome in Situ
    • Stefflova, K.; Chen, J.; Marotta, D.; Li, H.; Zheng, G. Photodynamic Therapy Agent with a Built-In Apoptosis Sensor for Evaluating Its Own Therapeutic Outcome in Situ J. Med. Chem. 2006, 49, 3850-3856 10.1021/jm060146u
    • (2006) J. Med. Chem. , vol.49 , pp. 3850-3856
    • Stefflova, K.1    Chen, J.2    Marotta, D.3    Li, H.4    Zheng, G.5
  • 117
    • 33846403749 scopus 로고    scopus 로고
    • Targeted Photodynamic Therapy Agent with a Built-In Apoptosis Sensor for in Vivo Near-Infrared Imaging of Tumor Apoptosis Triggered by Its Photosensitization in Situ
    • Stefflova, K.; Chen, J.; Li, H.; Zheng, G. Targeted Photodynamic Therapy Agent with a Built-In Apoptosis Sensor for In Vivo Near-Infrared Imaging of Tumor Apoptosis Triggered by Its Photosensitization In Situ Mol. Imaging 2006, 5, 520-532
    • (2006) Mol. Imaging , vol.5 , pp. 520-532
    • Stefflova, K.1    Chen, J.2    Li, H.3    Zheng, G.4
  • 118
    • 34547402139 scopus 로고    scopus 로고
    • Photodynamic Molecular Beacon as an Activatable Photosensitizer Based on Protease-Controlled Singlet Oxygen Quenching and Activation
    • Zheng, G.; Chen, J.; Stefflova, K.; Jarvi, M.; Li, H.; Wilson, B. C. Photodynamic Molecular Beacon as an Activatable Photosensitizer Based on Protease-Controlled Singlet Oxygen Quenching and Activation Proc. Natl. Acad. Sci. U. S. A. 2007, 104, 8989-8994 10.1073/pnas.0611142104
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 8989-8994
    • Zheng, G.1    Chen, J.2    Stefflova, K.3    Jarvi, M.4    Li, H.5    Wilson, B.C.6
  • 119
    • 79959240365 scopus 로고    scopus 로고
    • Imaging of Specific Activation of Photodynamic Molecular Beacons in Breast Cancer Vertebral Metastases
    • Liu, T. W.; Akens, M. K.; Chen, J.; Wise-Milestone, L.; Wilson, B. C.; Zheng, G. Imaging of Specific Activation of Photodynamic Molecular Beacons in Breast Cancer Vertebral Metastases Bioconjugate Chem. 2011, 22, 1021-1030 10.1021/bc200169x
    • (2011) Bioconjugate Chem. , vol.22 , pp. 1021-1030
    • Liu, T.W.1    Akens, M.K.2    Chen, J.3    Wise-Milestone, L.4    Wilson, B.C.5    Zheng, G.6
  • 120
    • 84960868327 scopus 로고    scopus 로고
    • Matrix Metalloproteinase-Based Photodynamic Molecular Beacons for Targeted Destruction of Bone Metastases in Vivo
    • Liu, T. W.; Akens, M. K.; Chen, J.; Wilson, B. C.; Zheng, G. Matrix Metalloproteinase-Based Photodynamic Molecular Beacons for Targeted Destruction of Bone Metastases in Vivo Photochem. Photobiol. Sci. 2016, 15, 375-381 10.1039/C5PP00414D
    • (2016) Photochem. Photobiol. Sci. , vol.15 , pp. 375-381
    • Liu, T.W.1    Akens, M.K.2    Chen, J.3    Wilson, B.C.4    Zheng, G.5
  • 121
    • 78650336753 scopus 로고    scopus 로고
    • Matrix Metalloproteinase Sensitive Gold Nanorod for Simultaneous Bioimaging and Photothermal Therapy of Cancer
    • Yi, D. K.; Sun, I.; Ryu, J. H.; Koo, H.; Park, C. W.; Youn, I.; Choi, K.; Kwon, I. C.; Kim, K.; Ahn, C. Matrix Metalloproteinase Sensitive Gold Nanorod for Simultaneous Bioimaging and Photothermal Therapy of Cancer Bioconjugate Chem. 2010, 21, 2173-2177 10.1021/bc100308p
    • (2010) Bioconjugate Chem. , vol.21 , pp. 2173-2177
    • Yi, D.K.1    Sun, I.2    Ryu, J.H.3    Koo, H.4    Park, C.W.5    Youn, I.6    Choi, K.7    Kwon, I.C.8    Kim, K.9    Ahn, C.10
  • 122
    • 79957753416 scopus 로고    scopus 로고
    • Enzyme-Responsive Multifunctional Magnetic Nanoparticles for Tumor Intracellular Drug Delivery and Imaging
    • Yang, Y.; Aw, J.; Chen, K.; Liu, F.; Padmanabhan, P.; Hou, Y.; Cheng, Z.; Xing, B. Enzyme-Responsive Multifunctional Magnetic Nanoparticles for Tumor Intracellular Drug Delivery and Imaging Chem.-Asian J. 2011, 6, 1381-1389 10.1002/asia.201000905
    • (2011) Chem. - Asian J. , vol.6 , pp. 1381-1389
    • Yang, Y.1    Aw, J.2    Chen, K.3    Liu, F.4    Padmanabhan, P.5    Hou, Y.6    Cheng, Z.7    Xing, B.8
  • 123
    • 84929603273 scopus 로고    scopus 로고
    • Enzyme-Specific Doxorubicin Drug Beacon as Drug-Resistant Theranostic Molecular Probes
    • Lock, L. L.; Tang, Z.; Keith, D.; Reyes, C.; Cui, H. Enzyme-Specific Doxorubicin Drug Beacon as Drug-Resistant Theranostic Molecular Probes ACS Macro Lett. 2015, 4, 552-555 10.1021/acsmacrolett.5b00170
    • (2015) ACS Macro Lett. , vol.4 , pp. 552-555
    • Lock, L.L.1    Tang, Z.2    Keith, D.3    Reyes, C.4    Cui, H.5
  • 125
    • 84875682931 scopus 로고    scopus 로고
    • Theranostic Nanoparticles with Controlled Release of Gemcitabine for Targeted Therapy and MRI of Pancreatic Cancer
    • Lee, G. Y.; Qian, W. P.; Wang, L.; Wang, Y. A.; Staley, C. a; Satpathy, M.; Nie, S.; Mao, H.; Yang, L. Theranostic Nanoparticles with Controlled Release of Gemcitabine for Targeted Therapy and MRI of Pancreatic Cancer ACS Nano 2013, 7, 2078-2089 10.1021/nn3043463
    • (2013) ACS Nano , vol.7 , pp. 2078-2089
    • Lee, G.Y.1    Qian, W.P.2    Wang, L.3    Wang, Y.A.4    Staley, C.A.5    Satpathy, M.6    Nie, S.7    Mao, H.8    Yang, L.9


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