PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo

Journal of Controlled Release

Volumn 209, Issue , 2015, Pages 238-247

  Veiman, Kadi Liis ^a   Künnapuu, Kadri ^a   Lehto, Tõnis ^a,b   Kiisholts, Kristina ^a   Pärn, Kalle ^a   Langel, Ülo ^a,b   Kurrikoff, Kaido ^a  

^a UNIVERSITY OF TARTU   (Estonia)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Cell penetrating peptide; Gene delivery; Matrix metalloprotease; Non covalent complexes; PEGylation; Tumor

Indexed keywords

DISEASE CONTROL; DNA; GENE EXPRESSION; GENE TRANSFER; GENES; LIPOSOMES; NANOPARTICLES; PEPTIDES; TUMORS;

CELL-PENETRATING PEPTIDE; GENE DELIVERY; MATRIX METALLOPROTEASE; NON-COVALENT COMPLEXES; PEGYLATION;

GENE THERAPY;

CELL PENETRATING PEPTIDE; GELATINASE A; MACROGOL; PLASMID DNA; DNA; LIPOPEPTIDE; LUCIFERASE; MACROGOL DERIVATIVE; NANOPARTICLE; PEPFECT14 PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GENE THERAPY; CARCINOGENESIS; CELL PROLIFERATION; CELL SUSPENSION; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; IN VIVO STUDY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN CONTENT; TUMOR GROWTH; ANIMAL; CELL LINE; CHEMISTRY; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; GENE TRANSFER; GENETICS; HAMSTER; HUMAN; METABOLISM; NEOPLASMS; PATHOLOGY; PLASMID; REPORTER GENE; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL-PENETRATING PEPTIDES; CHO CELLS; CRICETINAE; CRICETULUS; DNA; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENES, REPORTER; HUMANS; LIPOPEPTIDES; LUCIFERASES; MATRIX METALLOPROTEINASE 2; MICE; NANOPARTICLES; NEOPLASMS; PLASMIDS; POLYETHYLENE GLYCOLS; TUMOR BURDEN;

EID: 84928969440     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.04.038     Document Type: Article

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