Enzyme-Instructed Self-Assembly of Small d -Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells

Journal of the American Chemical Society

Volumn 138, Issue 11, 2016, Pages 3813-3823

  Zhou, Jie ^a   Du, Xuewen ^a   Yamagata, Natsuko ^a   Xu, Bing ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMIMETIC PROCESSES; BIOMIMETICS; CELL CULTURE; CELL DEATH; CHEMOTHERAPY; CYTOLOGY; DISEASES; ENZYMES; NANOFIBERS; PHOSPHATASES; SELF ASSEMBLY;

ALKALINE PHOSPHATASE; ANTI-CANCER THERAPEUTICS; BIOMIMETIC APPROACHES; ENZYMATIC DEPHOSPHORYLATION; INHIBITORY ACTIVITY; SELECTIVE INHIBITION; SELF ASSEMBLING MOLECULES; SELF-ASSEMBLING ABILITY;

CELLS;

ALKALINE PHOSPHATASE; ANTINEOPLASTIC AGENT; DEATH RECEPTOR; ENZYME INHIBITOR; NAPHTHYL GROUP; PHOSPHOTYROSINE; TRIPEPTIDE DERIVATIVE; WATER; NANOFIBER; OLIGOPEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER CELL; CANCER CELL LINE; CANCER INHIBITION; CANCER THERAPY; CELL DEATH; CELL FATE; CELL INTERACTION; CELL KILLING; CELL VIABILITY ASSAY; CELLS BY BODY ANATOMY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME INSTRUCTED SELF ASSEMBLY; ENZYME LOCALIZATION; ENZYME MECHANISM; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; PEPTIDE SYNTHESIS; PROTEIN ASSEMBLY; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SAOS 2 CELL LINE; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; NEOPLASMS; PHOSPHORYLATION; SYNTHESIS; TUMOR CELL LINE;

ALKALINE PHOSPHATASE; ANTINEOPLASTIC AGENTS; CELL DEATH; CELL LINE, TUMOR; HELA CELLS; HUMANS; NANOFIBERS; NEOPLASMS; OLIGOPEPTIDES; PHOSPHORYLATION;

EID: 84962109822     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b13541     Document Type: Article

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