A smart polymeric platform for multistage nucleus-targeted anticancer drug delivery

Biomaterials

Volumn 65, Issue , 2015, Pages 43-55

  Zhong, Jiaju ^a   Li, Lian ^a   Zhu, Xi ^a   Guan, Shan ^a   Yang, Qingqing ^a   Zhou, Zhou ^a   Zhang, Zhirong ^a   Huang, Yuan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Cancer therapy; Double stimuli responsive; Drug delivery; Multistage; Nucleus targeted; Polymer conjugates

Indexed keywords

CONTROLLED DRUG DELIVERY; DISEASES; DRUG DELIVERY; DRUG PRODUCTS; FUNCTIONAL POLYMERS; ONCOLOGY; PEPTIDES; SMART POLYMERS; TUMORS;

CANCER THERAPY; MULTISTAGE; NUCLEUS-TARGETED; POLYMER CONJUGATE; STIMULI-RESPONSIVE;

TARGETED DRUG DELIVERY;

ANTINEOPLASTIC AGENT; CELL PENETRATING PEPTIDE; COPOLYMER; H1 PEPTIDE; LYSOSOME ENZYME; N (2 HYDROXYPROPYL)METHACRYLAMIDE; PEPTIDE; POLYMER; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; DELAYED RELEASE FORMULATION; MYC PROTEIN; N-(2-HYDROXYPROPYL)METHACRYLAMIDE; NUCLEAR LOCALIZATION SIGNAL;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG PENETRATION; HUMAN; HUMAN CELL; INTERNALIZATION; MALE; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR PORE COMPLEX; PRIORITY JOURNAL; STIMULUS RESPONSE; TUMOR MICROENVIRONMENT; AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CELL NUCLEUS; CHEMISTRY; DELAYED RELEASE FORMULATION; HELA CELL LINE; METABOLISM; MOLECULAR GENETICS; NEOPLASMS; PATHOLOGY; PH; TUMOR CELL LINE;

ACRYLAMIDES; AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL NUCLEUS; CELL-PENETRATING PEPTIDES; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; NEOPLASMS; NUCLEAR LOCALIZATION SIGNALS; PEPTIDES; PROTO-ONCOGENE PROTEINS C-MYC;

EID: 84937403703     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.06.042     Document Type: Article

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