Enzyme-induced and tumor-targeted drug delivery system based on multifunctional mesoporous silica nanoparticles

ACS Applied Materials and Interfaces

Volumn 7, Issue 17, 2015, Pages 9078-9087

  Cheng, Yin Jia ^a   Luo, Guo Feng ^a   Zhu, Jing Yi ^a   Xu, Xiao Ding ^a   Zeng, Xuan ^a   Cheng, Dong Bing ^a   Li, You Mei ^a   Wu, Yan ^a   Zhang, Xian Zheng ^a   Zhuo, Ren Xi ^a   He, Feng ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Enzyme sensitive; mesoporous silica nanoparticle; Peptide; Rotaxane; Targeted drug delivery

Indexed keywords

AMINO ACIDS; BIOCOMPATIBILITY; CELL DEATH; CELL MEMBRANES; CELLS; CYTOLOGY; DISEASES; DRUG PRODUCTS; DRUG THERAPY; ENZYMES; MESOPOROUS MATERIALS; MOBILE SECURITY; MOLECULAR ELECTRONICS; NANOPARTICLES; ONCOLOGY; PEPTIDES; SILICA; TUMORS;

DRUG DELIVERY SYSTEM; MESOPOROUS SILICA NANOPARTICLES; MESOPOROUS SILICA PARTICLES; RESEARCH INTERESTS; ROTAXANES; TARGETED CANCER THERAPY; TARGETED DRUG DELIVERY; TUMOR-TARGETED DRUG DELIVERIES;

CONTROLLED DRUG DELIVERY;

ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; CATHEPSIN B; DELAYED RELEASE FORMULATION; DOXORUBICIN; ENZYME INHIBITOR; NANOCAPSULE; NANOCOMPOSITE; SILICON DIOXIDE;

ADMINISTRATION AND DOSAGE; CELL SURVIVAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG EFFECTS; HELA CELL LINE; HUMAN; METABOLISM; NANOPORE; PARTICLE SIZE; POROSITY; SYNTHESIS; ULTRASTRUCTURE;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; CATHEPSIN B; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DOXORUBICIN; ENZYME INHIBITORS; HELA CELLS; HUMANS; NANOCAPSULES; NANOCOMPOSITES; NANOPORES; PARTICLE SIZE; POROSITY; SILICON DIOXIDE;

EID: 84928962934     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b00752     Document Type: Article

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