Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

Nature Communications

Volumn 8, Issue , 2017, Pages

  Sergin, Ismail ^a   Evans, Trent D ^a   Zhang, Xiangyu ^a   Bhattacharya, Somashubhra ^a   Stokes, Carl J ^a   Song, Eric ^a   Ali, Sahl ^a   Dehestani, Babak ^a   Holloway, Karyn B ^a   Micevych, Paul S ^a   Javaheri, Ali ^a   Crowley, Jan R ^a   Ballabio, Andrea ^b   Schilling, Joel D ^a   Epelman, Slava ^c   Weihl, Conrad C ^a   Diwan, Abhinav ^a   Fan, Daping ^d   Zayed, Mohamed A ^a   Razani, Babak ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; PROTEIN AGGREGATE; TREHALOSE; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; LIGHT CHAIN 3, HUMAN; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; SEQUESTOSOME 1; SQSTM1 PROTEIN, MOUSE; TCFEB PROTEIN, MOUSE;

BIOGENIC MATERIAL; CARDIOVASCULAR DISEASE; DEGRADATION; EXPERIMENTAL STUDY; GENE EXPRESSION; GENETIC MARKER; LIPID; PROTEIN; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; AUTOPHAGY; CONTROLLED STUDY; GENE OVEREXPRESSION; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; ORGANELLE BIOGENESIS; PERITONEUM MACROPHAGE; ANIMAL; C57BL MOUSE; DRUG EFFECT; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; ATHEROSCLEROSIS; AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; HUMANS; LYSOSOMES; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; PLAQUE, ATHEROSCLEROTIC; SEQUESTOSOME-1 PROTEIN; TREHALOSE;

EID: 85020683001     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms15750     Document Type: Article

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