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Volumn 105, Issue 8, 2000, Pages 1049-1056

Targeted disruption of the class B, scavenger receptor CD36 protects against atherosclerotic lesion development in mice

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; LOW DENSITY LIPOPROTEIN; SCAVENGER RECEPTOR;

EID: 0034101821     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI9259     Document Type: Article
Times cited : (864)

References (57)
  • 1
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross, R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature: 362:801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 2
    • 0031870652 scopus 로고    scopus 로고
    • Macrophages in human arheroma contain PPAR-gamma: Differentiationdependent peroxisomnl proliferator-activated receptor gamma (PPAR-gamma) expression and reduction of MMP-9 activity through PPAR-gamma activation in mononuclear phagocytes in vitro
    • Marx, N., Sukhova, G., Murphy, C., Libby, P., and Plurzky, J. 1998. Macrophages in human arheroma contain PPAR-gamma: differentiationdependent peroxisomnl proliferator-activated receptor gamma (PPAR-gamma) expression and reduction of MMP-9 activity through PPAR-gamma activation in mononuclear phagocytes in vitro. Am. J. Pathol. 153:17-23.
    • (1998) Am. J. Pathol. , vol.153 , pp. 17-23
    • Marx, N.1    Sukhova, G.2    Murphy, C.3    Libby, P.4    Plurzky, J.5
  • 3
    • 0025954705 scopus 로고
    • Expression of monocytes chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions
    • Yla-Herttuala, S., et al. 1991. Expression of monocytes chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc. Natl. Acad. Sci. USA. 88:5252-5256.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5252-5256
    • Yla-Herttuala, S.1
  • 4
    • 0032572719 scopus 로고    scopus 로고
    • Decreased lesion formation in CCR2 mice reveals a role for chemokines in the initiation of atherosclerosis
    • Boring, L., Gosling, J., Cleary, M., and Charo, I.F. 1998. Decreased lesion formation in CCR2 mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 394:894-897.
    • (1998) Nature , vol.394 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, I.F.4
  • 5
    • 0031977846 scopus 로고    scopus 로고
    • Macrophage phenotype in mice deficient in both macrophage-colony-stimulating factor (op) and apolipoprotein E
    • de Villiers, W.J., et al. 1998. Macrophage phenotype in mice deficient in both macrophage-colony-stimulating factor (op) and apolipoprotein E. Arterioscler.Thromb Vasc. Biol. 18:631-640.
    • (1998) Arterioscler.thromb Vasc. Biol. , vol.18 , pp. 631-640
    • De Villiers, W.J.1
  • 6
    • 0026762638 scopus 로고
    • Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages
    • Geng, Y.J., and Hansson, G.K. 1992. Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages. J. Clin. Invest. 89:1322-1330.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1322-1330
    • Geng, Y.J.1    Hansson, G.K.2
  • 7
    • 0027849722 scopus 로고
    • Induction of chemotactic cytokines by minimally oxidized LDL
    • Berliner, J.A., et al. 1993. Induction of chemotactic cytokines by minimally oxidized LDL. Adv. Exp. Med. Biol. 351:13-18.
    • (1993) Adv. Exp. Med. Biol. , vol.351 , pp. 13-18
    • Berliner, J.A.1
  • 8
    • 0025021490 scopus 로고
    • Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line u937
    • Frostegard, J., et al. 1990. Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line U937. Proc. Natl. Acad. Sci. USA. 87:904-908.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 904-908
    • Frostegard, J.1
  • 9
    • 0029966853 scopus 로고    scopus 로고
    • Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotem
    • Ramprasad, M.P., Terpstra, V., Kondratenko, N., Quehenberger, O., and Steinberg, D. 1996. Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotem. Proc. Natl. Acad. Sci. USA. 93:14833-14838.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14833-14838
    • Ramprasad, M.P.1    Terpstra, V.2    Kondratenko, N.3    Quehenberger, O.4    Steinberg, D.5
  • 10
    • 0022509638 scopus 로고
    • Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor
    • Parthasarathy, S., Printz, D.J., Boyd, D., Joy, L., and Sreinberg, D. 1986. Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor. Arteriosclerosis. 6:505-510.
    • (1986) Arteriosclerosis , vol.6 , pp. 505-510
    • Parthasarathy, S.1    Printz, D.J.2    Boyd, D.3    Joy, L.4    Sreinberg, D.5
  • 11
    • 0026607501 scopus 로고
    • Molecular flypaper and atherosclerosis: Structure of the macrophage scavenger receptor
    • Krieger, M. 1992. Molecular flypaper and atherosclerosis: structure of the macrophage scavenger receptor. Trends Biochem. Sci. 17:141-146.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 141-146
    • Krieger, M.1
  • 12
    • 0027280397 scopus 로고
    • CD36 is a receptor for oxidized low density lipoprotein
    • Endemann, G., et al. 1993. CD36 is a receptor for oxidized low density lipoprotein. J. Biol. Chem. 268:11811-11816.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11811-11816
    • Endemann, G.1
  • 13
    • 0032169220 scopus 로고    scopus 로고
    • Recognizing death: The phagocytosis of apoptotic cells
    • Platt, N., da Silva, R.P., and Gordon, S. 1998. Recognizing death: the phagocytosis of apoptotic cells. Trends Cell Biol. 8:365-372.
    • (1998) Trends Cell Biol. , vol.8 , pp. 365-372
    • Platt, N.1    Da Silva, R.P.2    Gordon, S.3
  • 14
    • 0026631158 scopus 로고
    • The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis
    • Parthasarathy, S., Steinberg, D., and Witztum, J.L. 1992. The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis. Annu. Rev. Med. 43:219-225.
    • (1992) Annu. Rev. Med. , vol.43 , pp. 219-225
    • Parthasarathy, S.1    Steinberg, D.2    Witztum, J.L.3
  • 15
    • 0028022781 scopus 로고
    • Oxidized lipoproteins, altered cell function and atherosclerosis
    • Penn, M.S., and Chisolm, G.M. 1994. Oxidized lipoproteins, altered cell function and atherosclerosis. Atherosclerosis. 108(Suppl.):21-29.
    • (1994) Atherosclerosis , vol.108 , Issue.SUPPL. , pp. 21-29
    • Penn, M.S.1    Chisolm, G.M.2
  • 16
    • 0030799043 scopus 로고    scopus 로고
    • Low density lipoprorein oxidation and its pathobiological significance
    • Steinberg, D. 1997. Low density lipoprorein oxidation and its pathobiological significance. J. Biol. Chem. 272:20963-20966.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20963-20966
    • Steinberg, D.1
  • 17
    • 0031807232 scopus 로고    scopus 로고
    • Minimally oxidized low-density lipoprotein increases expression of scavenger receptor A, CD36, and macrosialin in resident mouse peritoneal macrophages
    • Yoshida, H., Quehenberger, O., Kondratenko, N., Green, S., and Steinberg, D. 1998. Minimally oxidized low-density lipoprotein increases expression of scavenger receptor A, CD36, and macrosialin in resident mouse peritoneal macrophages. Arterioscler. Thromb. Vasc. Biol. 18:794-802.
    • (1998) Arterioscler. Thromb. Vasc. Biol. , vol.18 , pp. 794-802
    • Yoshida, H.1    Quehenberger, O.2    Kondratenko, N.3    Green, S.4    Steinberg, D.5
  • 18
    • 0030758289 scopus 로고    scopus 로고
    • Native and modified low density lipoproteins increase the functional expression of the macrophage class B scavenger receptor, CD36
    • Han, J., Hajjar, D.P., Febbraio, M., and Nicholson, A.C. 1997. Native and modified low density lipoproteins increase the functional expression of the macrophage class B scavenger receptor, CD36. J. Biol. Chem. 272:21654-21659.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21654-21659
    • Han, J.1    Hajjar, D.P.2    Febbraio, M.3    Nicholson, A.C.4
  • 19
    • 0031748833 scopus 로고    scopus 로고
    • Lipoproteins modulate expression of the macrophage scavenger receptor
    • Han, J., and Nicholson, A.C. 1998. Lipoproteins modulate expression of the macrophage scavenger receptor Am. J. Pathol. 152:1647-1654.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1647-1654
    • Han, J.1    Nicholson, A.C.2
  • 20
    • 1842293994 scopus 로고    scopus 로고
    • High affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type I/II
    • Lougheed, M., et al. 1997. High affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type I/II. J. Biol. Chem. 272:12938-12944.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12938-12944
    • Lougheed, M.1
  • 21
    • 0034051080 scopus 로고    scopus 로고
    • Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species
    • Podrez, E.A., et al. 2000 Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species. J. Clin. Invest. 105:1095-1108.
    • (2000) J. Clin. Invest. , vol.105 , pp. 1095-1108
    • Podrez, E.A.1
  • 22
    • 0030895048 scopus 로고    scopus 로고
    • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection
    • Suzuki, H., et al. 1997. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature. 386:292-296.
    • (1997) Nature , vol.386 , pp. 292-296
    • Suzuki, H.1
  • 23
    • 0031958704 scopus 로고    scopus 로고
    • Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice
    • Sakaguchi, H., et al. 1998. Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice. Lab Invest. 78:423-434.
    • (1998) Lab Invest. , vol.78 , pp. 423-434
    • Sakaguchi, H.1
  • 24
    • 0032977440 scopus 로고    scopus 로고
    • Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APO-E3 Leiden transgenic mice
    • de Winther, M.P., et al. 1999. Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APO-E3 Leiden transgenic mice. Atherosclerosis. 144:315-321.
    • (1999) Atherosclerosis , vol.144 , pp. 315-321
    • De Winther, M.P.1
  • 26
    • 0000685254 scopus 로고    scopus 로고
    • Regulated expression of CD36 during monocyte-to-macrophage differentiation: Potential role of CD36 in foam cell formation
    • Huh, H.V., Pearce, S.F., Yesner, L.M., Schindler, J.L, and Silverstein, R.L. 1996. Regulated expression of CD36 during monocyte-to-macrophage differentiation: potential role of CD36 in foam cell formation. Blood. 87:2020-2028.
    • (1996) Blood , vol.87 , pp. 2020-2028
    • Huh, H.V.1    Pearce, S.F.2    Yesner, L.M.3    Schindler, J.L.4    Silverstein, R.L.5
  • 27
    • 0026643681 scopus 로고
    • Macrophage differentiation in atherosclerosis: An in situ immunohistochemical analysis in humans
    • Wal, A.C., Das, P.K., Tigges, A.J., and Becker, A.F. 1992. Macrophage differentiation in atherosclerosis: an in situ immunohistochemical analysis in humans. Am. J. Pathol. 141:161-168.
    • (1992) Am. J. Pathol. , vol.141 , pp. 161-168
    • Wal, A.C.1    Das, P.K.2    Tigges, A.J.3    Becker, A.F.4
  • 28
    • 0032914253 scopus 로고    scopus 로고
    • CD36, a novel receptor for oxidized low-density lipoproteins, is highly expressed on lipid-laden macrophages in human atherosclerotic aorta
    • Nakata, A., et al. 1999. CD36, a novel receptor for oxidized low-density lipoproteins, is highly expressed on lipid-laden macrophages in human atherosclerotic aorta. Arterioscler. Thromb. Vasc. Biol. 19:1333-1339.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 1333-1339
    • Nakata, A.1
  • 29
    • 0001506684 scopus 로고    scopus 로고
    • Cellular cholesterol regulates expression of the macrophage type B scavenger receptor, CD36
    • Han, J., Hajjar, D.P., Tauras, J.M., and Nicholson, A.C. 1999. Cellular cholesterol regulates expression of the macrophage type B scavenger receptor, CD36. J. Lipid Res. 40:830-838.
    • (1999) J. Lipid Res. , vol.40 , pp. 830-838
    • Han, J.1    Hajjar, D.P.2    Tauras, J.M.3    Nicholson, A.C.4
  • 30
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR-gamma
    • Nagy, L., Tontonoz, P., Alvarez, J.G., Chen, H., and Evans, R.M. 1998. Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR-gamma. Cell. 93:229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 31
    • 0032540012 scopus 로고    scopus 로고
    • PPAR-gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz, P., Nagy, L., Alvarez, J.G., Thomazy, V.A., and Evans, R.M. 1998. PPAR-gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93:241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 32
    • 0028838178 scopus 로고
    • Putative membrane fatty acid translocate and cytoplasmic fatty acid-binding protein are co-expressed in rat heart and skeletal muscles
    • Van Nieuwenhoven, F.A., et al. 1995. Putative membrane fatty acid translocate and cytoplasmic fatty acid-binding protein are co-expressed in rat heart and skeletal muscles. Biochem. Biophys. Res. Commun. 207:747-752.
    • (1995) Biochem. Biophys. Res. Commun. , vol.207 , pp. 747-752
    • Van Nieuwenhoven, F.A.1
  • 33
    • 0030022233 scopus 로고    scopus 로고
    • CD36 participates in the phagocytosis of rod outer segments by retinal pigment epithelium
    • Ryeom, S.W., Sparrow, J.R., and Silverstein, R.L. 1996. CD36 participates in the phagocytosis of rod outer segments by retinal pigment epithelium. J. Cell. Sci. 109:387-395.
    • (1996) J. Cell. Sci. , vol.109 , pp. 387-395
    • Ryeom, S.W.1    Sparrow, J.R.2    Silverstein, R.L.3
  • 34
    • 0025299573 scopus 로고
    • PAS IV, an integral membrane protein of mammary epithelial cells, is related to platelet and endothelial cell CD36 (GP IV)
    • Greenwalt, D.E., Watt, K.W., So, O.Y., and Jiwani, N. 1990. PAS IV, an integral membrane protein of mammary epithelial cells, is related to platelet and endothelial cell CD36 (GP IV). Biochemistry. 29:7054-7059.
    • (1990) Biochemistry , vol.29 , pp. 7054-7059
    • Greenwalt, D.E.1    Watt, K.W.2    So, O.Y.3    Jiwani, N.4
  • 35
    • 0027240176 scopus 로고
    • Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36
    • Abumrad, N.A., el-Maghrabi, M.R., Amri, E.Z., Lopez, E., and Grimaldi, P.A. 1993. Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36. J. Biol. Chem. 268:17665-17668.
    • (1993) J. Biol. Chem. , vol.268 , pp. 17665-17668
    • Abumrad, N.A.1    El-Maghrabi, M.R.2    Amri, E.Z.3    Lopez, E.4    Grimaldi, P.A.5
  • 36
    • 0033516477 scopus 로고    scopus 로고
    • A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism
    • Febbraio, M., et al. 1999. A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J. Biol. Chem. 274:19055-19062.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19055-19062
    • Febbraio, M.1
  • 37
    • 0033578604 scopus 로고    scopus 로고
    • Muscle-specific over-expression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin
    • Ibrahimi, A., et al. 1999. Muscle-specific over-expression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J. Biol. Chem. 274:26761-26765.
    • (1999) J. Biol. Chem. , vol.274 , pp. 26761-26765
    • Ibrahimi, A.1
  • 38
    • 0032958470 scopus 로고    scopus 로고
    • Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
    • Aitman, T.J., et al. 1999. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat. Genet. 21:76-83.
    • (1999) Nat. Genet. , vol.21 , pp. 76-83
    • Aitman, T.J.1
  • 39
    • 0028025262 scopus 로고
    • Human apolipoprorein A-1 gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse
    • Plump, A.S., Scott, C.J., and Breslow, J.L. 1994. Human apolipoprorein A-1 gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc. Natl. Acad.Sci. USA. 91:9607-9611.
    • (1994) Proc. Natl. Acad.sci. USA , vol.91 , pp. 9607-9611
    • Plump, A.S.1    Scott, C.J.2    Breslow, J.L.3
  • 40
    • 0018178434 scopus 로고
    • A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
    • Markwell, M.A., Haas, S.M., Bieber, L.L., and Tolbert, N.E. 1978. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal. Biochem. 87:206-210.
    • (1978) Anal. Biochem. , vol.87 , pp. 206-210
    • Markwell, M.A.1    Haas, S.M.2    Bieber, L.L.3    Tolbert, N.E.4
  • 41
    • 0028060607 scopus 로고
    • Inactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophages
    • Hoppe, G., O'Neil, J., and Hoff, H.F. 1994. Inactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophages. J. Clin. Invest. 94:1506-1512.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1506-1512
    • Hoppe, G.1    O'Neil, J.2    Hoff, H.F.3
  • 42
    • 0009627006 scopus 로고
    • Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
    • Goldstein, J.L., Ho, Y.K., Basu, S.K., and Brown, M.S. 1979. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc. Natl. Acad. Sci. USA. 76:333-337.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 333-337
    • Goldstein, J.L.1    Ho, Y.K.2    Basu, S.K.3    Brown, M.S.4
  • 43
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa, H., Ohishi, N., and Yagi, K. 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95:351-358.
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 44
    • 0032701646 scopus 로고    scopus 로고
    • Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
    • Podrez, E.A., Schmitt, D., Hoff, H.F., and Hazen, S.L. 1999. Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro. J. Clin. Invest. 103:1547-1560.
    • (1999) J. Clin. Invest. , vol.103 , pp. 1547-1560
    • Podrez, E.A.1    Schmitt, D.2    Hoff, H.F.3    Hazen, S.L.4
  • 45
    • 0025017863 scopus 로고
    • Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system
    • Rakita, R.M., Michel, B.R., and Rosen, H. 1990. Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system. Biochemistry. 29:1075-1080.
    • (1990) Biochemistry , vol.29 , pp. 1075-1080
    • Rakita, R.M.1    Michel, B.R.2    Rosen, H.3
  • 46
    • 0026725757 scopus 로고
    • Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
    • Plump, A.S., et al. 1992. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell. 71:343-353.
    • (1992) Cell , vol.71 , pp. 343-353
    • Plump, A.S.1
  • 47
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
    • Zhang, S.H., Reddick, R.L., Piedrahita, J.A., and Maeda, N. 1992. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science. 258:468-471.
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 48
    • 0027958084 scopus 로고
    • Apo E-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
    • Nakashima, Y., Plump, A.S., Raines, E.W., Breslow, J.L., and Ross, R. 1994. Apo E-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb. 14:133-140.
    • (1994) Arterioscler Thromb. , vol.14 , pp. 133-140
    • Nakashima, Y.1    Plump, A.S.2    Raines, E.W.3    Breslow, J.L.4    Ross, R.5
  • 49
    • 0028929744 scopus 로고
    • A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: Partial purification and role in recognition of oxidatively damaged cells
    • Ottnad, E., et al. 1995. A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells. Proc. Natl. Acad Sci. USA. 92:1391-1395.
    • (1995) Proc. Natl. Acad Sci. USA , vol.92 , pp. 1391-1395
    • Ottnad, E.1
  • 50
    • 0028841044 scopus 로고
    • The 94-to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68
    • Ramprasad, M.P., et al. 1995. The 94-to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68. Proc. Natl. Acad. Sci. USA. 92:9580-9584.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9580-9584
    • Ramprasad, M.P.1
  • 51
    • 0004968087 scopus 로고
    • Low density lipoprotein undergoes oxidative modification in vivo
    • Palinski, W., et al. 1989. Low density lipoprotein undergoes oxidative modification in vivo. Proc Natl. Acad. Sci. USA. 86:1372-1376.
    • (1989) Proc Natl. Acad. Sci. USA , vol.86 , pp. 1372-1376
    • Palinski, W.1
  • 52
    • 0029957467 scopus 로고    scopus 로고
    • Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprorein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma
    • Palinski, W., et al. 1996. Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprorein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma. J. Clin. Invest. 98:800-814.
    • (1996) J. Clin. Invest. , vol.98 , pp. 800-814
    • Palinski, W.1
  • 53
    • 0024439446 scopus 로고
    • Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man
    • Yla-Herttuala, S., et al. 1989. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J. Clin. Invest. 84:1086-1095.
    • (1989) J. Clin. Invest. , vol.84 , pp. 1086-1095
    • Yla-Herttuala, S.1
  • 54
    • 0028963942 scopus 로고
    • Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site
    • Nicholson, A.C., Frieda, S., Pearce, A., and Silverstein, R.L. 1995. Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site. Arterioscler. Thromb. Vasc. Biol. 15:269-275.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 269-275
    • Nicholson, A.C.1    Frieda, S.2    Pearce, A.3    Silverstein, R.L.4
  • 55
    • 0028834455 scopus 로고
    • Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects
    • Nozaki, S., et al. 1995. Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects. J. Clin. Invest. 96:1859-1865.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1859-1865
    • Nozaki, S.1
  • 56
    • 0030979720 scopus 로고    scopus 로고
    • 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima
    • Hazen, S.L., and Heinecke, J.W. 1997. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J. Clin. Invest. 99:2075-2081.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2075-2081
    • Hazen, S.L.1    Heinecke, J.W.2
  • 57
    • 0032752579 scopus 로고    scopus 로고
    • Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice
    • Cyrus, T., et al. 1999. Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. J. Clin. Invest. 103:1597-1604.
    • (1999) J. Clin. Invest. , vol.103 , pp. 1597-1604
    • Cyrus, T.1


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