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Volumn 112, Issue 5, 2015, Pages E420-E429

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

Author keywords

[No Author keywords available]

Indexed keywords

AXIN 1; BETA CATENIN; CD63 ANTIGEN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; RAB7 PROTEIN; TETRACYCLINE; UNCLASSIFIED DRUG; WNT PROTEIN; GLYCOGEN SYNTHASE KINASE 3; MITF PROTEIN, HUMAN;

EID: 84922311449     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1424576112     Document Type: Article
Times cited : (194)

References (67)
  • 1
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling: Components, mechanisms, and diseases
    • MacDonald BT, Tamai K, He X (2009) Wnt/β-catenin signaling: Components, mechanisms, and diseases. Dev Cell 17(1):9-26.
    • (2009) Dev Cell , vol.17 , Issue.1 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 2
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S, Moon RT (2009) Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 10(7):468-477.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.7 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 3
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling and disease
    • Clevers H, Nusse R (2012) Wnt/β-catenin signaling and disease. Cell 149(6):1192-1205.
    • (2012) Cell , vol.149 , Issue.6 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 4
    • 77149174855 scopus 로고    scopus 로고
    • Wnt signaling from development to disease: Insights from model systems
    • Cadigan KM, Peifer M (2009) Wnt signaling from development to disease: Insights from model systems. Cold Spring Harb Perspect Biol 1(2):a002881.
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , Issue.2 , pp. a002881
    • Cadigan, K.M.1    Peifer, M.2
  • 5
    • 0028047389 scopus 로고
    • Wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo
    • Peifer M, Sweeton D, Casey M, Wieschaus E (1994) Wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. Development 120(2):369-380.
    • (1994) Development , vol.120 , Issue.2 , pp. 369-380
    • Peifer, M.1    Sweeton, D.2    Casey, M.3    Wieschaus, E.4
  • 6
    • 78650484935 scopus 로고    scopus 로고
    • Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
    • Taelman VF, et al. (2010) Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell 143(7):1136-1148.
    • (2010) Cell , vol.143 , Issue.7 , pp. 1136-1148
    • Taelman, V.F.1
  • 7
    • 84901229628 scopus 로고    scopus 로고
    • Mitotic wnt signaling promotes protein stabilization and regulates cell size
    • Acebron SP, Karaulanov E, Berger BS, Huang Y-L, Niehrs C (2014) Mitotic wnt signaling promotes protein stabilization and regulates cell size. Mol Cell 54(4):663-674.
    • (2014) Mol Cell , vol.54 , Issue.4 , pp. 663-674
    • Acebron, S.P.1    Karaulanov, E.2    Berger, B.S.3    Huang, Y.-L.4    Niehrs, C.5
  • 8
    • 34250827150 scopus 로고    scopus 로고
    • Wnt induces LRP6 signalosomes and promotes dishevelleddependent LRP6 phosphorylation
    • Bilić J, et al. (2007) Wnt induces LRP6 signalosomes and promotes dishevelleddependent LRP6 phosphorylation. Science 316(5831):1619-1622.
    • (2007) Science , vol.316 , Issue.5831 , pp. 1619-1622
    • BilićJ1
  • 9
    • 84893725748 scopus 로고    scopus 로고
    • Multivesicular GSK3 sequestration upon Wnt signaling is controlled by p120-catenin/cadherin interaction with LRP5/6
    • Vinyoles M, et al. (2014) Multivesicular GSK3 sequestration upon Wnt signaling is controlled by p120-catenin/cadherin interaction with LRP5/6. Mol Cell 53(3):444-457.
    • (2014) Mol Cell , vol.53 , Issue.3 , pp. 444-457
    • Vinyoles, M.1
  • 10
    • 77950863406 scopus 로고    scopus 로고
    • Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
    • Wollert T, Hurley JH (2010) Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature 464(7290):864-869.
    • (2010) Nature , vol.464 , Issue.7290 , pp. 864-869
    • Wollert, T.1    Hurley, J.H.2
  • 11
    • 0028062014 scopus 로고
    • Microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family
    • Hemesath TJ, et al. (1994) microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. Genes Dev 8(22):2770-2780.
    • (1994) Genes Dev , vol.8 , Issue.22 , pp. 2770-2780
    • Hemesath, T.J.1
  • 12
    • 34548212430 scopus 로고    scopus 로고
    • MiT transcription factor associated malignancies in man
    • Davis IJ, Fisher DE (2007) MiT transcription factor associated malignancies in man. Cell Cycle 6(14):1724-1729.
    • (2007) Cell Cycle , vol.6 , Issue.14 , pp. 1724-1729
    • Davis, I.J.1    Fisher, D.E.2
  • 13
    • 80052753295 scopus 로고    scopus 로고
    • Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer
    • Haq R, Fisher DE (2011) Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer. J Clin Oncol 29(25):3474-3482.
    • (2011) J Clin Oncol , vol.29 , Issue.25 , pp. 3474-3482
    • Haq, R.1    Fisher, D.E.2
  • 14
    • 0034142326 scopus 로고    scopus 로고
    • C-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi
    • Wu M, et al. (2000) c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi. Genes Dev 14(3):301-312.
    • (2000) Genes Dev , vol.14 , Issue.3 , pp. 301-312
    • Wu, M.1
  • 15
    • 84876920718 scopus 로고    scopus 로고
    • A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts
    • Ferron M, et al. (2013) A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts. Genes Dev 27(8):955-969.
    • (2013) Genes Dev , vol.27 , Issue.8 , pp. 955-969
    • Ferron, M.1
  • 16
    • 0014098516 scopus 로고
    • The eye and skeletal effects of two mutant alleles at the microphthalmia locus of Mus musculus
    • Packer SO (1967) The eye and skeletal effects of two mutant alleles at the microphthalmia locus of Mus musculus. J Exp Zool 165(1):21-45.
    • (1967) J Exp Zool , vol.165 , Issue.1 , pp. 21-45
    • Packer, S.O.1
  • 17
    • 0027204149 scopus 로고
    • Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein
    • Hodgkinson CA, et al. (1993) Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell 74(2):395-404.
    • (1993) Cell , vol.74 , Issue.2 , pp. 395-404
    • Hodgkinson, C.A.1
  • 18
    • 10944234560 scopus 로고    scopus 로고
    • Melanocytes and the microphthalmia transcription factor network
    • Steingrímsson E, Copeland NG, Jenkins NA (2004) Melanocytes and the microphthalmia transcription factor network. Annu Rev Genet 38(1):365-411.
    • (2004) Annu Rev Genet , vol.38 , Issue.1 , pp. 365-411
    • Steingrímsson, E.1    Copeland, N.G.2    Jenkins, N.A.3
  • 19
    • 21844478747 scopus 로고    scopus 로고
    • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
    • Garraway LA, et al. (2005) Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature 436(7047):117-122.
    • (2005) Nature , vol.436 , Issue.7047 , pp. 117-122
    • Garraway, L.A.1
  • 20
    • 82555187007 scopus 로고    scopus 로고
    • A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
    • Yokoyama S, et al. (2011) A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature 480(7375):99-103.
    • (2011) Nature , vol.480 , Issue.7375 , pp. 99-103
    • Yokoyama, S.1
  • 21
    • 0029917487 scopus 로고    scopus 로고
    • Identification of a melanocyte-type promoter of the microphthalmia-associated transcription factor gene
    • Fuse N, Yasumoto K, Suzuki H, Takahashi K, Shibahara S (1996) Identification of a melanocyte-type promoter of the microphthalmia-associated transcription factor gene. Biochem Biophys Res Commun 219(3):702-707.
    • (1996) Biochem Biophys Res Commun , vol.219 , Issue.3 , pp. 702-707
    • Fuse, N.1    Yasumoto, K.2    Suzuki, H.3    Takahashi, K.4    Shibahara, S.5
  • 22
    • 67749122634 scopus 로고    scopus 로고
    • A gene network regulating lysosomal biogenesis and function
    • Sardiello M, et al. (2009) A gene network regulating lysosomal biogenesis and function. Science 325(5939):473-477.
    • (2009) Science , vol.325 , Issue.5939 , pp. 473-477
    • Sardiello, M.1
  • 23
    • 84862539692 scopus 로고    scopus 로고
    • The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis
    • Roczniak-Ferguson A, et al. (2012) The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Sci Signal 5(228):ra42.
    • (2012) Sci Signal , vol.5 , Issue.228 , pp. ra42
    • Roczniak-Ferguson, A.1
  • 24
    • 84857997408 scopus 로고    scopus 로고
    • A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
    • Settembre C, et al. (2012) A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J 31(5):1095-1108.
    • (2012) EMBO J , vol.31 , Issue.5 , pp. 1095-1108
    • Settembre, C.1
  • 25
    • 84893055506 scopus 로고    scopus 로고
    • The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris
    • Martina JA, et al. (2014) The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris. Sci Signal 7(309):ra9.
    • (2014) Sci Signal , vol.7 , Issue.309 , pp. ra9
    • Martina, J.A.1
  • 26
    • 84870407757 scopus 로고    scopus 로고
    • Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment
    • Dobrowolski R, et al. (2012) Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment. Cell Reports 2(5):1316-1328.
    • (2012) Cell Reports , vol.2 , Issue.5 , pp. 1316-1328
    • Dobrowolski, R.1
  • 27
    • 80655134725 scopus 로고    scopus 로고
    • TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes
    • Settembre C, Ballabio A (2011) TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes. Autophagy 7(11):1379-1381.
    • (2011) Autophagy , vol.7 , Issue.11 , pp. 1379-1381
    • Settembre, C.1    Ballabio, A.2
  • 28
    • 0035488986 scopus 로고    scopus 로고
    • The renaissance of GSK3
    • Cohen P, Frame S (2001) The renaissance of GSK3. Nat Rev Mol Cell Biol 2(10):769-776.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , Issue.10 , pp. 769-776
    • Cohen, P.1    Frame, S.2
  • 29
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, et al. (2005) Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102(43):15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1
  • 30
    • 56249119207 scopus 로고    scopus 로고
    • Novel MITF targets identified using a two-step DNA microarray strategy
    • Hoek KS, et al. (2008) Novel MITF targets identified using a two-step DNA microarray strategy. Pigment Cell Melanoma Res 21(6):665-676.
    • (2008) Pigment Cell Melanoma Res , vol.21 , Issue.6 , pp. 665-676
    • Hoek, K.S.1
  • 31
    • 84878606239 scopus 로고    scopus 로고
    • TFEB controls cellular lipid metabolism through a starva-tion-induced autoregulatory loop
    • Settembre C, et al. (2013) TFEB controls cellular lipid metabolism through a starva-tion-induced autoregulatory loop. Nat Cell Biol 15(6):647-658.
    • (2013) Nat Cell Biol , vol.15 , Issue.6 , pp. 647-658
    • Settembre, C.1
  • 32
    • 84904346902 scopus 로고    scopus 로고
    • RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway
    • Alonso-Curbelo D, et al. (2014) RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway. Cancer Cell 26(1):61-76.
    • (2014) Cancer Cell , vol.26 , Issue.1 , pp. 61-76
    • Alonso-Curbelo, D.1
  • 33
    • 80052716148 scopus 로고    scopus 로고
    • Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
    • Palmieri M, et al. (2011) Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. Hum Mol Genet 20(19):3852-3866.
    • (2011) Hum Mol Genet , vol.20 , Issue.19 , pp. 3852-3866
    • Palmieri, M.1
  • 34
    • 70350100352 scopus 로고    scopus 로고
    • Hear the Wnt Ror: How melanoma cells adjust to changes in Wnt
    • O'Connell MP, Weeraratna AT (2009) Hear the Wnt Ror: How melanoma cells adjust to changes in Wnt. Pigment Cell Melanoma Res 22(6):724-739.
    • (2009) Pigment Cell Melanoma Res , vol.22 , Issue.6 , pp. 724-739
    • O'Connell, M.P.1    Weeraratna, A.T.2
  • 35
    • 84861972831 scopus 로고    scopus 로고
    • Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex
    • Li VSW, et al. (2012) Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex. Cell 149(6):1245-1256.
    • (2012) Cell , vol.149 , Issue.6 , pp. 1245-1256
    • Li, V.S.W.1
  • 36
    • 0037968710 scopus 로고    scopus 로고
    • MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma
    • Du J, et al. (2003) MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma. Am J Pathol 163(1):333-343.
    • (2003) Am J Pathol , vol.163 , Issue.1 , pp. 333-343
    • Du, J.1
  • 37
    • 38849203228 scopus 로고    scopus 로고
    • In vivo switching of human melanoma cells between proliferative and invasive states
    • Hoek KS, et al. (2008) In vivo switching of human melanoma cells between proliferative and invasive states. Cancer Res 68(3):650-656.
    • (2008) Cancer Res , vol.68 , Issue.3 , pp. 650-656
    • Hoek, K.S.1
  • 38
    • 84923171755 scopus 로고    scopus 로고
    • Genes involved in the WNT and vesicular trafficking pathways are associated with melanoma predisposition
    • Ibarrola-Villava M, et al. (2014) Genes involved in the WNT and vesicular trafficking pathways are associated with melanoma predisposition. Int J Cancer, 10.1002/ ijc.29257.
    • (2014) Int J Cancer
    • Ibarrola-Villava, M.1
  • 39
    • 79956120349 scopus 로고    scopus 로고
    • Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
    • Strub T, et al. (2011) Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene 30(20):2319-2332.
    • (2011) Oncogene , vol.30 , Issue.20 , pp. 2319-2332
    • Strub, T.1
  • 40
    • 33747882661 scopus 로고    scopus 로고
    • MITF: Master regulator of melanocyte development and melanoma oncogene
    • Levy C, Khaled M, Fisher DE (2006) MITF: Master regulator of melanocyte development and melanoma oncogene. Trends Mol Med 12(9):406-414.
    • (2006) Trends Mol Med , vol.12 , Issue.9 , pp. 406-414
    • Levy, C.1    Khaled, M.2    Fisher, D.E.3
  • 41
    • 0035911146 scopus 로고    scopus 로고
    • Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells
    • Raposo G, Tenza D, Murphy DM, Berson JF, Marks MS (2001) Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells. J Cell Biol 152(4):809-824.
    • (2001) J Cell Biol , vol.152 , Issue.4 , pp. 809-824
    • Raposo, G.1    Tenza, D.2    Murphy, D.M.3    Berson, J.F.4    Marks, M.S.5
  • 42
    • 34648828526 scopus 로고    scopus 로고
    • Melanosomes-Dark organelles enlighten endosomal membrane transport
    • Raposo G, Marks MS (2007) Melanosomes-Dark organelles enlighten endosomal membrane transport. Nat Rev Mol Cell Biol 8(10):786-797.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.10 , pp. 786-797
    • Raposo, G.1    Marks, M.S.2
  • 43
    • 12244267707 scopus 로고    scopus 로고
    • Proteomic analysis of early melanosomes: Identification of novel melanosomal proteins
    • Basrur V, et al. (2003) Proteomic analysis of early melanosomes: Identification of novel melanosomal proteins. J Proteome Res 2(1):69-79.
    • (2003) J Proteome Res , vol.2 , Issue.1 , pp. 69-79
    • Basrur, V.1
  • 44
    • 33750979817 scopus 로고    scopus 로고
    • Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes
    • Chi A, et al. (2006) Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. J Proteome Res 5(11):3135-3144.
    • (2006) J Proteome Res , vol.5 , Issue.11 , pp. 3135-3144
    • Chi, A.1
  • 45
    • 84903314885 scopus 로고    scopus 로고
    • Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasis
    • Martina JA, Diab HI, Li H, Puertollano R (2014) Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasis. Cell Mol Life Sci 71(13):2483-2497.
    • (2014) Cell Mol Life Sci , vol.71 , Issue.13 , pp. 2483-2497
    • Martina, J.A.1    Diab, H.I.2    Li, H.3    Puertollano, R.4
  • 46
    • 84876664386 scopus 로고    scopus 로고
    • Cancer-associated lysosomal changes: Friends or foes?
    • Kallunki T, Olsen OD, Jäättelä M (2013) Cancer-associated lysosomal changes: Friends or foes? Oncogene 32(16):1995-2004.
    • (2013) Oncogene , vol.32 , Issue.16 , pp. 1995-2004
    • Kallunki, T.1    Olsen, O.D.2    Jäättelä, M.3
  • 47
    • 79954503631 scopus 로고    scopus 로고
    • Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma
    • Valsesia A, et al. (2011) Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma. PLoS ONE 6(4):e18369.
    • (2011) PLoS ONE , vol.6 , Issue.4 , pp. e18369
    • Valsesia, A.1
  • 48
    • 80755138384 scopus 로고    scopus 로고
    • In melanoma, beta-catenin is a suppressor of invasion
    • Arozarena I, et al. (2011) In melanoma, beta-catenin is a suppressor of invasion. Oncogene 30(45):4531-4543.
    • (2011) Oncogene , vol.30 , Issue.45 , pp. 4531-4543
    • Arozarena, I.1
  • 49
    • 59049101982 scopus 로고    scopus 로고
    • Activated Wnt/β-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model
    • Chien AJ, et al. (2009) Activated Wnt/β-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proc Natl Acad Sci USA 106(4):1193-1198.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.4 , pp. 1193-1198
    • Chien, A.J.1
  • 50
    • 0034799321 scopus 로고    scopus 로고
    • Loss of β-catenin expression associated with disease progression in malignant melanoma
    • Kageshita T, et al. (2001) Loss of β-catenin expression associated with disease progression in malignant melanoma. Br J Dermatol 145(2):210-216.
    • (2001) Br J Dermatol , vol.145 , Issue.2 , pp. 210-216
    • Kageshita, T.1
  • 51
    • 84855696067 scopus 로고    scopus 로고
    • Wnt/β -catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma
    • Biechele TL, et al. (2012) Wnt/β -catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma. Sci Signal 5(206):ra3.
    • (2012) Sci Signal , vol.5 , Issue.206 , pp. ra3
    • Biechele, T.L.1
  • 52
    • 77956266718 scopus 로고    scopus 로고
    • A re-evaluation of the "oncogenic" nature of Wnt/β-catenin signaling in melanoma and other cancers
    • Lucero OM, Dawson DW, Moon RT, Chien AJ (2010) A re-evaluation of the "oncogenic" nature of Wnt/β-catenin signaling in melanoma and other cancers. Curr Oncol Rep 12(5):314-318.
    • (2010) Curr Oncol Rep , vol.12 , Issue.5 , pp. 314-318
    • Lucero, O.M.1    Dawson, D.W.2    Moon, R.T.3    Chien, A.J.4
  • 53
    • 65249128611 scopus 로고    scopus 로고
    • Identification of targets of the Wnt pathway destruction complex in addition to β-catenin
    • Kim N-G, Xu C, Gumbiner BM (2009) Identification of targets of the Wnt pathway destruction complex in addition to β-catenin. Proc Natl Acad Sci USA 106(13): 5165-5170.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.13 , pp. 5165-5170
    • Kim, N.-G.1    Xu, C.2    Gumbiner, B.M.3
  • 54
    • 0034650485 scopus 로고    scopus 로고
    • Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway
    • Dorsky RI, Raible DW, Moon RT (2000) Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway. Genes Dev 14(2): 158-162.
    • (2000) Genes Dev , vol.14 , Issue.2 , pp. 158-162
    • Dorsky, R.I.1    Raible, D.W.2    Moon, R.T.3
  • 55
    • 0034640443 scopus 로고    scopus 로고
    • Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a
    • Takeda K, et al. (2000) Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a. J Biol Chem 275(19):14013-14016.
    • (2000) J Biol Chem , vol.275 , Issue.19 , pp. 14013-14016
    • Takeda, K.1
  • 56
    • 84908410074 scopus 로고    scopus 로고
    • The roles of microphthalmia-associated transcription factor and pigmentation in melanoma
    • Hsiao JJ, Fisher DE (2014) The roles of microphthalmia-associated transcription factor and pigmentation in melanoma. Arch Biochem Biophys 563:28-34.
    • (2014) Arch Biochem Biophys , vol.563 , pp. 28-34
    • Hsiao, J.J.1    Fisher, D.E.2
  • 57
    • 82555205202 scopus 로고    scopus 로고
    • A SUMOylationdefective MITF germline mutation predisposes to melanoma and renal carcinoma
    • French Familial Melanoma Study Group
    • Bertolotto C, et al.; French Familial Melanoma Study Group (2011) A SUMOylationdefective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature 480(7375):94-98.
    • (2011) Nature , vol.480 , Issue.7375 , pp. 94-98
    • Bertolotto, C.1
  • 58
    • 77952577623 scopus 로고    scopus 로고
    • MITF-A matter of life and death for developing melanocytes
    • The Progression To Malignancy, eds Hearing VJ, Leong SPL Humana, Totowa, NJ
    • Arnheiter H, et al. (2007) MITF-A matter of life and death for developing melanocytes. From Melanocytes to Melanoma: The Progression to Malignancy, eds Hearing VJ, Leong SPL (Humana, Totowa, NJ), pp 27-49.
    • (2007) From Melanocytes to Melanoma , pp. 27-49
    • Arnheiter, H.1
  • 59
    • 0034110297 scopus 로고    scopus 로고
    • Ser298 of MITF, a mutation site in Waardenburg syndrome type 2, is a phosphorylation site with functional significance
    • Takeda K, et al. (2000) Ser298 of MITF, a mutation site in Waardenburg syndrome type 2, is a phosphorylation site with functional significance. Hum Mol Genet 9(1): 125-132.
    • (2000) Hum Mol Genet , vol.9 , Issue.1 , pp. 125-132
    • Takeda, K.1
  • 60
    • 71149083533 scopus 로고    scopus 로고
    • Main roads to melanoma
    • Palmieri G, et al. (2009) Main roads to melanoma. J Transl Med 7(1):86.
    • (2009) J Transl Med , vol.7 , Issue.1 , pp. 86
    • Palmieri, G.1
  • 61
    • 24144477947 scopus 로고    scopus 로고
    • Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation
    • Wellbrock C, Marais R (2005) Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation. J Cell Biol 170(5):703-708.
    • (2005) J Cell Biol , vol.170 , Issue.5 , pp. 703-708
    • Wellbrock, C.1    Marais, R.2
  • 62
    • 84875758730 scopus 로고    scopus 로고
    • Lessons from the cancer genome
    • Garraway LA, Lander ES (2013) Lessons from the cancer genome. Cell 153(1):17-37.
    • (2013) Cell , vol.153 , Issue.1 , pp. 17-37
    • Garraway, L.A.1    Lander, E.S.2
  • 63
    • 33845711166 scopus 로고    scopus 로고
    • Mitf regulation of Dia1 controls melanoma proliferation and invasiveness
    • Carreira S, et al. (2006) Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev 20(24):3426-3439.
    • (2006) Genes Dev , vol.20 , Issue.24 , pp. 3426-3439
    • Carreira, S.1
  • 64
    • 78049237405 scopus 로고    scopus 로고
    • Cancer stem cells versus phenotype-switching in melanoma
    • Hoek KS, Goding CR (2010) Cancer stem cells versus phenotype-switching in melanoma. Pigment Cell Melanoma Res 23(6):746-759.
    • (2010) Pigment Cell Melanoma Res , vol.23 , Issue.6 , pp. 746-759
    • Hoek, K.S.1    Goding, C.R.2
  • 65
    • 79956131573 scopus 로고    scopus 로고
    • Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny
    • Cheli Y, et al. (2011) Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny. Oncogene 30(20):2307-2318.
    • (2011) Oncogene , vol.30 , Issue.20 , pp. 2307-2318
    • Cheli, Y.1
  • 66
    • 84880044594 scopus 로고    scopus 로고
    • Directed phenotype switching as an effective antimelanoma strategy
    • Sáez-Ayala M, et al. (2013) Directed phenotype switching as an effective antimelanoma strategy. Cancer Cell 24(1):105-119.
    • (2013) Cancer Cell , vol.24 , Issue.1 , pp. 105-119
    • Sáez-Ayala, M.1
  • 67
    • 0346875916 scopus 로고    scopus 로고
    • GSK-3-selective inhibitors derived from Tyrian purple indirubins
    • Meijer L, et al. (2003) GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol 10(12):1255-1266.
    • (2003) Chem Biol , vol.10 , Issue.12 , pp. 1255-1266
    • Meijer, L.1


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