Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis

Science Signaling

Volumn 9, Issue 409, 2016, Pages

  Sergin, Ismail ^a   Bhattacharya, Somashubhra ^a   Emanuel, Roy ^a   Esen, Emel ^a   Stokes, Carl J ^a   Evans, Trent D ^a   Arif, Batool ^a   Curci, John A ^b   Razani, Babak ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5; CHOLESTEROL; CRYOPYRIN; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; LIPID; LIPOPOLYSACCHARIDE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDIZED LOW DENSITY LIPOPROTEIN; POLYUBIQUITIN; PROTEIN; PROTEIN AGGREGATE; PROTEIN KINASE C; PROTEIN P62; TRANSCRIPTION FACTOR NRF2; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ASSOCIATED FACTOR; UNCLASSIFIED DRUG; APOLIPOPROTEIN E; ATG5 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN 5; CARRIER PROTEIN; HEAT SHOCK PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NLRP3 PROTEIN, MOUSE; SEQUESTOSOME 1; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, MOUSE; UBIQUITINATED PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ROOT; APOPTOSIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; AUTOFLUORESCENCE; AUTOPHAGY; CARBOXY TERMINAL SEQUENCE; CELL INCLUSION; CELL LYSATE; CELLULAR DISTRIBUTION; CHOLESTEROL BLOOD LEVEL; CYTOKINE RELEASE; CYTOPLASM; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE MICROSCOPY; LYSOSOME; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; WILD TYPE; ANIMAL; ATHEROSCLEROSIS; C57BL MOUSE; CELL CULTURE; FLUORESCENCE MICROSCOPY; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; RNA INTERFERENCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; CARRIER PROTEINS; CELLS, CULTURED; CYTOPLASM; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOBLOTTING; INCLUSION BODIES; INFLAMMASOMES; INTERLEUKIN-1BETA; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; POLYUBIQUITIN; RNA INTERFERENCE; SEQUESTOSOME-1 PROTEIN; UBIQUITINATED PROTEINS;

EID: 84954481862     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aad5614     Document Type: Article

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