Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics

Journal of Controlled Release

Volumn 200, Issue , 2015, Pages 87-96

  Maas, Sybren L N ^a   De Vrij, Jeroen ^a   Van Der Vlist, Els J ^b   Geragousian, Biaina ^a   Van Bloois, Louis ^c   Mastrobattista, Enrico ^c   Schiffelers, Raymond M ^a   Wauben, Marca H M ^b   Broekman, Marike L D ^a   Nolte 'T Hoen, Esther N M ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Exosomes; Extracellular vesicles; High resolution flow cytometry; Liposomes; Nanoparticle tracking analysis; Tunable resistive pulse sensing

Indexed keywords

DIAGNOSIS; DRUG DELIVERY; FLOW CYTOMETRY; NANOPARTICLES;

EXOSOMES; EXTRACELLULAR; HIGH RESOLUTION; NANOPARTICLE TRACKING ANALYSIS; RESISTIVE PULSE SENSING;

LIPOSOMES;

CALCEIN; CALCEIN LOADED LIPOSOME; LIPOSOME; POLYSTYRENE; UNCLASSIFIED DRUG; BIOMIMETIC MATERIAL; NANOPARTICLE;

ARTICLE; CANCER CELL LINE; CELL VACUOLE; COMPARATIVE STUDY; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DYNAMIC LIGHT SCATTERING; EXTRACELLULAR VESICLE; FLOW CYTOMETRY; HETEROGENEITY; HUMAN; HUMAN CELL; LIGHT SCATTERING; LIMIT OF DETECTION; NANOPARTICLE TRACKING ANALYSIS; NANOPORE; NANOTECHNOLOGY; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REFRACTION INDEX; TUNABLE RESISTIVE PULSE SENSING; EXOSOME; TUMOR CELL LINE;

BIOMIMETIC MATERIALS; CELL LINE, TUMOR; EXOSOMES; FLOW CYTOMETRY; HUMANS; LIPOSOMES; NANOPARTICLES;

EID: 84920736138     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.12.041     Document Type: Article

References (42)

1. S. El Andaloussi, I. Mager, X.O. Breakefield, and M.J. Wood Extracellular vesicles: biology and emerging therapeutic opportunities Nat. Rev. Drug Discov. 12 5 2013 347 357
2. A. Bobrie, M. Colombo, G. Raposo, and C. Thery Exosome secretion: molecular mechanisms and roles in immune responses Traffic 12 12 2011 1659 1668
3. J. Kowal, M. Tkach, and C. Thery Biogenesis and secretion of exosomes Curr. Opin. Cell Biol. 29C 2014 116 125
4. P.D. Robbins, and A.E. Morelli Regulation of immune responses by extracellular vesicles Nat. Rev. Immunol. 14 3 2014 195 208
5. I. Del Conde, C.N. Shrimpton, P. Thiagarajan, and J.A. Lopez Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Blood 106 5 2005 1604 1611
6. S. Gatti, S. Bruno, and M.C. Deregibus Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury Nephrol. Dial. Transplant. 26 5 2011 1474 1483
7. J. Skog, T. Wurdinger, and S. Van Rijn Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Nat. Cell Biol. 10 12 2008 1470 1476
8. K. Al-Nedawi, B. Meehan, and J. Micallef Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Nat. Cell Biol. 10 5 2008 619 624
9. S. Saman, W. Kim, and M. Raya Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease J. Biol. Chem. 287 6 2012 3842 3849
10. H. Zhou, T. Pisitkun, and A. Aponte Exosomal fetuin-A identified by proteomics: a novel urinary biomarker for detecting acute kidney injury Kidney Int. 70 10 2006 1847 1857
11. H. Shao, J. Chung, and L. Balaj Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy Nat. Med. 18 12 2012 1835 1840
12. D. Sun, X. Zhuang, and X. Xiang A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes Mol. Ther. 18 9 2010 1606 1614
13. R. Van Der Meel, M.H. Fens, P. Vader, W.W. Van Solinge, O. Eniola-Adefeso, and R.M. Schiffelers Extracellular vesicles as drug delivery systems: lessons from the liposome field J. Control. Release 195 2014 72 85
14. S.M. Van Dommelen, P. Vader, and S. Lakhal Microvesicles and exosomes: opportunities for cell-derived membrane vesicles in drug delivery J. Control. Release 161 2 2012 635 644
15. K.W. Witwer, E.I. Buzas, and L.T. Bemis Standardization of sample collection, isolation and analysis methods in extracellular vesicle research J. Extracell. Vesicles 2 2013
16. R.A. Dragovic, C. Gardiner, and A.S. Brooks Sizing and phenotyping of cellular vesicles using nanoparticle tracking analysis Nanomedicine 7 6 2011 780 788
17. C. Gardiner, Y.J. Ferreira, R.A. Dragovic, C.W. Redman, and I.L. Sargent Extracellular vesicle sizing and enumeration by nanoparticle tracking analysis J. Extracell. Vesicles 2 2013
18. J. De Vrij, S.L. Maas, and M. Van Nispen Quantification of nanosized extracellular membrane vesicles with scanning ion occlusion sensing Nanomedicine 8 9 2013 1443 1458
19. E.N. Nolte-'T Hoen, E.J. Van Der Vlist, and M. Aalberts Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles Nanomedicine 8 5 2012 712 720
20. V. Filipe, A. Hawe, and W. Jiskoot Critical evaluation of nanoparticle tracking analysis (NTA) by nanosight for the measurement of nanoparticles and protein aggregates Pharm. Res. 27 5 2010 796 810
21. G.S. Roberts, D. Kozak, W. Anderson, M.F. Broom, R. Vogel, and M. Trau Tunable nano/micropores for particle detection and discrimination: scanning ion occlusion spectroscopy Small 6 23 2010 2653 2658
22. D. Kozak, W. Anderson, R. Vogel, S. Chen, F. Antaw, and M. Trau Simultaneous size and zeta-potential measurements of individual nanoparticles in dispersion using size-tunable pore sensors ACS Nano 6 8 2012 6990 6997
23. R. Vogel, G. Willmott, and D. Kozak Quantitative sizing of nano/microparticles with a tunable elastomeric pore sensor Anal. Chem. 83 9 2011 3499 3506
24. G.R. Willmott, R. Vogel, and S.S. Yu Use of tunable nanopore blockade rates to investigate colloidal dispersions J. Phys. Condens. Matter 22 45 2010 454116
25. G.S. Roberts, S. Yu, and Q. Zeng Tunable pores for measuring concentrations of synthetic and biological nanoparticle dispersions Biosens. Bioelectron. 31 1 2012 17 25
26. E. Van Der Pol, M.J. Van Gemert, A. Sturk, R. Nieuwland, and T.G. Van Leeuwen Single vs. swarm detection of microparticles and exosomes by flow cytometry J. Thromb. Haemost. 10 5 2012 919 930
27. J.A. Gallego-Urrea, J. Tuoriniemi, and M. Hassellöv Applications of particle-tracking analysis to the determination of size distributions and concentrations of nanoparticles in environmental, biological and food samples TrAC Trends Anal. Chem. 30 3 2011 473 483
28. P. Van Der Meeren, M. Kasinos, and H. Saveyn Relevance of two-dimensional Brownian motion dynamics in applying nanoparticle tracking analysis Methods Mol. Biol. 906 2012 525 534
29. E.J. Van Der Vlist, E.N. Nolte-'T Hoen, W. Stoorvogel, G.J. Arkesteijn, and M.H. Wauben Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry Nat. Protoc. 7 7 2012 1311 1326
30. W. Anderson, D. Kozak, V.A. Coleman, A.K. Jamting, and M. Trau A comparative study of submicron particle sizing platforms: accuracy, precision and resolution analysis of polydisperse particle size distributions J. Colloid Interface Sci. 405 2013 322 330
31. N.C. Bell, C. Minelli, J. Tompkins, M.M. Stevens, and A.G. Shard Emerging techniques for submicrometer particle sizing applied to Stober silica Langmuir 28 29 2012 10860 10872
32. E. Van Der Pol, F.A. Coumans, and A.E. Grootemaat Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing J. Thromb. Haemost. 12 7 2014 1182 1192
33. Z. Varga, Y. Yuana, and A.E. Grootemaat Towards traceable size determination of extracellular vesicles J. Extracell. Vesicles 3 2014
34. G. Rouser, S. Fkeischer, and A. Yamamoto Two dimensional then layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots Lipids 5 5 1970 494 496
35. S.L.N. Maas, J. De Vrij, and M.L.D. Broekman Quantification and size-profiling of extracellular vesicles using tunable resistive pulse sensing J. Vis. Exp. 92 Oct 19 2014 e51623
36. E. Van Der Pol, F. Coumans, Z. Varga, M. Krumrey, and R. Nieuwland Innovation in detection of microparticles and exosomes J. Thromb. Haemost. 11 Suppl. 1 2013 36 45
37. G.R. Willmott, R. Chaturvedi, S.J.W. Cummins, and L.G. Groenewegen Actuation of tunable elastomeric pores: resistance measurements and finite element modelling Exp. Mech. 54 2 2013 153 163
38. C. Pidgeon, and C.A. Hunt Calculating number and surface area of liposomes in any suspension J. Pharm. Sci. 70 2 1981 173 176
39. D. Kozak, W. Anderson, and M. Trau Tuning particle velocity and measurement sensitivity by changing pore sensor dimensions Chem. Lett. 41 10 2012 1134 1136
40. D. Marimpietri, A. Petretto, and L. Raffaghello Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression PLoS One 8 9 2013 e75054
41. J.L. Hood, R.S. San, and S.A. Wickline Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis Cancer Res. 71 11 2011 3792 3801
42. V. Sokolova, A.K. Ludwig, and S. Hornung Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy Colloids Surf. B: Biointerfaces 87 1 2011 146 150