메뉴 건너뛰기




Volumn 4, Issue 5, 2015, Pages 513-522

Human umbilical cord mesenchymal stem cell exosomes enhance angiogenesis through the Wnt4/β-catenin pathway

Author keywords

Angiogenesis; Exosomes; Regenerative medicine; Wnt4; Catenin

Indexed keywords

BETA CATENIN; CD31 ANTIGEN; CD63 ANTIGEN; CD81 ANTIGEN; CD9 ANTIGEN; CYCLIN D3; HEAT SHOCK PROTEIN 70; LENTIVIRUS VECTOR; N BENZYL 1,2,3,4,8,9 HEXAHYDRO 6 (4 HYDROXYBENZYL) 8 (1 NAPHTHYLMETHYL) 4,7 DIOXO 2H PYRAZINO [1,2 A] PYRIMIDINE 1 (6H) CARBOXAMIDE; NERVE CELL ADHESION MOLECULE; UNCLASSIFIED DRUG; UVOMORULIN; WNT4 PROTEIN; FUSED HETEROCYCLIC RINGS; N BENZYL 1,2,3,4,8,9 HEXAHYDRO 6 (4 HYDROXYBENZYL) 8 (1 NAPHTHYLMETHYL) 4,7 DIOXO 2H PYRAZINO[1,2 A]PYRIMIDINE 1(6H) CARBOXAMIDE; PYRIMIDINONE DERIVATIVE; WNT4 PROTEIN, HUMAN;

EID: 84930424126     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2014-0267     Document Type: Article
Times cited : (402)

References (52)
  • 1
    • 84875587586 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from Wharton’s jelly of the umbilical cord: Biological properties and emerging clinical applica
    • Batsali AK, Kastrinaki MC, Papadaki HA et al. Mesenchymal stem cells derived from Wharton’s jelly of the umbilical cord: Biological properties and emerging clinical applications. Curr Stem Cell Res Ther 2013;8:144–155.
    • (2013) Curr Stem Cell Res Ther , vol.8 , pp. 155
    • Batsali, A.K.1    Kastrinaki, M.C.2    Papadaki, H.A.3
  • 2
    • 84905486101 scopus 로고    scopus 로고
    • Mesenchymalstem cell lines isolated by different isolation methods show variations in the regulation of graft-versus-host disease
    • Yoo HS, Yi T, Cho YK et al. Mesenchymal stem cell lines isolated by different isolation methods show variations in the regulation of graft-versus-host disease. Immune Netw 2013; 13:133–140.
    • (2013) Immune Netw , vol.13 , pp. 133-140
    • Yoo, H.S.1    Yi, T.2    Cho, Y.K.3
  • 3
    • 77955361735 scopus 로고    scopus 로고
    • Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythemato-sus
    • Sun L, Wang D, Liang J et al. Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythemato-sus. Arthritis Rheum 2010;62:2467–2475.
    • (2010) Arthritis Rheum , vol.62 , pp. 2467-2475
    • Sun, L.1    Wang, D.2    Liang, J.3
  • 4
    • 84890559123 scopus 로고    scopus 로고
    • Roleofmes-
    • Wang X, Wang Y, Gou W et al. Roleofmes-enchymal stem cells in bone regeneration and fracture repair: A review. Int Orthop 2013;37: 2491–2498.
    • (2013) Int Orthop , vol.37 , pp. 2491-2498
    • Wang, X.1    Wang, Y.2    Gou, W.3
  • 5
    • 84891373674 scopus 로고    scopus 로고
    • Towards clinical application of mesenchymal stem cells for treatment of neurological dis-easesofthe central nervous system
    • Laroni A, Novi G, Kerlero de Rosbo N et al. Towards clinical application of mesenchymal stem cells for treatment of neurological dis-easesofthe central nervous system.JNeuroim-mune Pharmacol 2013;8:1062–1076.
    • (2013) Jneuroim- , vol.8 , pp. 1062-1076
    • Laroni, A.1    Novi, G.2    De Kerlero Rosbo, N.3
  • 6
    • 59849123877 scopus 로고    scopus 로고
    • Mesenchymal stem cells from human umbilical cords ameliorate mouse hepaticinjuryinvivo
    • Yan Y, Xu W, Qian H et al. Mesenchymal stem cells from human umbilical cords ameliorate mouse hepaticinjuryinvivo. Liver Int 2009; 29:356–365.
    • (2009) Liver Int , vol.29 , pp. 356-365
    • Yan, Y.1    Xu, W.2    Qian, H.3
  • 7
    • 77952238570 scopus 로고    scopus 로고
    • Mesenchymalstem cells derived from human umbilical cord ameliorate ischemia/reperfusion-induced acute renal failure in rats
    • Cao H, Qian H, Xu W et al. Mesenchymal stem cells derived from human umbilical cord ameliorate ischemia/reperfusion-induced acute renal failure in rats. Biotechnol Lett 2010;32: 725–732.
    • (2010) Biotechnol Lett , vol.32 , pp. 725-732
    • Cao, H.1    Qian, H.2    Xu, W.3
  • 8
    • 34247854809 scopus 로고    scopus 로고
    • Vasculo-tropic, paracrine actions of infused mesenchy-mal stem cells are important to the recovery from acute kidney injury
    • Tögel F, Weiss K, Yang Y et al. Vasculo-tropic, paracrine actions of infused mesenchy-mal stem cells are important to the recovery from acute kidney injury. Am J Physiol Renal Physiol 2007;292:F1626–F1635.
    • (2007) Am J Physiol Renal Physiol , vol.292 , pp. F1626-F1635
    • Tögel, F.1    Weiss, K.2    Yang, Y.3
  • 9
    • 73849109910 scopus 로고    scopus 로고
    • Paracrine/endocrine mechanism of stem cells on kidney repair: Role of microvesicle-mediated transfer of genetic information
    • Camussi G, Deregibus MC, Tetta C. Paracrine/endocrine mechanism of stem cells on kidney repair: Role of microvesicle-mediated transfer of genetic information. Curr Opin Nephrol Hypertens 2010;19:7–12.
    • (2010) Curr Opin Nephrol Hypertens , vol.19 , pp. 7-12
    • Camussi, G.1    Deregibus, M.C.2    Tetta, C.3
  • 10
    • 84865482681 scopus 로고    scopus 로고
    • New players in cell-cell communication
    • Bang C, Thum T. Exosomes: New players in cell-cell communication. Int J Biochem Cell Biol 2012;44:2060–2064.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 2060-2064
    • Bang, C.1    Exosomes, T.T.2
  • 11
    • 77952293014 scopus 로고    scopus 로고
    • Exosomesecreted by MSC reduces myocardial ischemia/reperfusion injury
    • Lai RC, Arslan F, Lee MM et al. Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem Cell Res (Amst) 2010;4:214–222.
    • (2010) Stem Cell Res (Amst) , vol.4 , pp. 214-222
    • Lai, R.C.1    Arslan, F.2    Lee, M.M.3
  • 12
    • 84876241933 scopus 로고    scopus 로고
    • Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis
    • Li T, Yan Y, Wang B et al. Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis. Stem Cells Dev 2013;22:845–854.
    • (2013) Stem Cells Dev , vol.22 , pp. 845-854
    • Li, T.1    Yan, Y.2    Wang, B.3
  • 13
    • 84876875077 scopus 로고    scopus 로고
    • Exosomes released by human umbilical cord mesenchy-mal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro
    • Zhou Y, Xu H, Xu W et al. Exosomes released by human umbilical cord mesenchy-mal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro. Stem Cell Res Ther 2013;4:34.
    • (2013) Stem Cell Res Ther , vol.4 , pp. 34
    • Zhou, Y.1    Xu, H.2    Xu, W.3
  • 14
    • 34248160926 scopus 로고    scopus 로고
    • The role of angio-poietin 2 in hyperoxia-induced acute lung injury
    • Bhandari V, Elias JA. The role of angio-poietin 2 in hyperoxia-induced acute lung injury. Cell Cycle 2007;6:1049–1052.
    • (2007) Cell Cycle , vol.6 , pp. 1049-1052
    • Bhandari, V.1    Elias, J.A.2
  • 15
    • 84875126728 scopus 로고    scopus 로고
    • Yla¨-Herttuala S. Promoting blood vessel growth in ischemic diseases: Challenges in translating preclinical potential into clinical success
    • Dragneva G, Korpisalo P, Yla¨-Herttuala S. Promoting blood vessel growth in ischemic diseases: Challenges in translating preclinical potential into clinical success. Dis Model Mech 2013;6:312–322.
    • (2013) Dis Model Mech , vol.6 , pp. 312-322
    • Dragneva, G.1    Korpisalo, P.2
  • 16
    • 84883195088 scopus 로고    scopus 로고
    • Angiogenesis and its therapeutic opportunities
    • 2013
    • Yoo SY, Kwon SM. Angiogenesis and its therapeutic opportunities. Mediators Inflamm 2013;2013:127170.
    • (2013) Mediators Inflamm , pp. 127170
    • Yoo, S.Y.1    Kwon, S.M.2
  • 17
    • 84898461927 scopus 로고    scopus 로고
    • Extracellularvesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
    • Bian S, Zhang L, Duan L et al. Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model. J Mol Med (Berl) 2014;92:387–397.
    • (2014) J Mol Med (Berl) , vol.92 , pp. 387-397
    • Bian, S.1    Zhang, L.2    Duan, L.3
  • 18
    • 84919393345 scopus 로고    scopus 로고
    • Dall’Aglio Cet al. Membrane vesicles mediate pro-angiogenic activity of equine adipose-derived mesenchymal stromal cells
    • Pascucci L, Alessandri G, Dall’Aglio Cet al. Membrane vesicles mediate pro-angiogenic activity of equine adipose-derived mesenchymal stromal cells. Vet J 2014;202:361–6.
    • (2014) Vet J , vol.202 , pp. 361-366
    • Pascucci, L.1    Alessandri, G.2
  • 19
    • 84880475762 scopus 로고    scopus 로고
    • Endothelial cells require miR-214 to secrete exosomes that suppress senescenceand induce angiogenesis in human and mouse endothelial cells
    • van Balkom BW, de Jong OG, Smits M et al. Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells. Blood 2013;121:3997–4006, S1–S15.
    • (2013) Blood , vol.121 , Issue.3997-4006 , pp. SS1-S15
    • Van Balkom, B.W.1    De Jong, O.G.2    Smits, M.3
  • 20
    • 84890107684 scopus 로고    scopus 로고
    • Microvesicle-delivery miR-150 promotes tumorigenesis by up-regulating VEGF, and the neutralization of miR-150 attenuate tumor development
    • Liu Y, Zhao L, Li D et al. Microvesicle-delivery miR-150 promotes tumorigenesis by up-regulating VEGF, and the neutralization of miR-150 attenuate tumor development. Protein Cell 2013;4:932–941.
    • (2013) Protein Cell , vol.4 , pp. 932-941
    • Liu, Y.1    Zhao, L.2    Li, D.3
  • 21
    • 84888986034 scopus 로고    scopus 로고
    • Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells
    • Tadokoro H, Umezu T, Ohyashiki K et al. Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J Biol Chem 2013;288:34343–34351.
    • (2013) J Biol Chem , vol.288 , pp. 34343-34351
    • Tadokoro, H.1    Umezu, T.2    Ohyashiki, K.3
  • 22
    • 84919680938 scopus 로고    scopus 로고
    • Exo-somal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1
    • Umezu T, Tadokoro H, Azuma K et al. Exo-somal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1. Blood 2014;124: 3748–3757.
    • (2014) Blood , vol.124 , pp. 3748-3757
    • Umezu, T.1    Tadokoro, H.2    Azuma, K.3
  • 23
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • Kucharzewska P, Christianson HC, Welch JE et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci USA 2013;110: 7312–7317.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 7312-7317
    • Kucharzewska, P.1    Christianson, H.C.2    Welch, J.E.3
  • 24
    • 84861560095 scopus 로고    scopus 로고
    • Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a Src-dependent fashion
    • Mineo M, Garfield SH, Taverna S et al. Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a Src-dependent fashion. Angiogenesis 2012;15:33–45.
    • (2012) Angiogenesis , vol.15 , pp. 45
    • Mineo, M.1    Garfield, S.H.2    Taverna, S.3
  • 25
    • 39149133635 scopus 로고    scopus 로고
    • Human mes-enchymal stem cells isolated from the umbilical cord
    • Qiao C, Xu W, Zhu W et al. Human mes-enchymal stem cells isolated from the umbilical cord. Cell Biol Int 2008;32:8–15.
    • (2008) Cell Biol Int , vol.32 , pp. 8-15
    • Qiao, C.1    Xu, W.2    Zhu, W.3
  • 26
    • 81955167406 scopus 로고    scopus 로고
    • Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo
    • Zhu W, Huang L, Li Y et al. Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo. Cancer Lett 2012;315:28–37.
    • (2012) Cancer Lett , vol.315 , pp. 28-37
    • Zhu, W.1    Huang, L.2    Li, Y.3
  • 27
    • 76849113987 scopus 로고    scopus 로고
    • Lentivirus-modified human umbilical cord mesenchymal stem cells maintain their pluripotency
    • Qian H, Zhang X, Xu W et al. Lentivirus-modified human umbilical cord mesenchymal stem cells maintain their pluripotency. Biotech-nol Appl Biochem 2010;55:53–62.
    • (2010) Biotech-Nol Appl Biochem , vol.55 , pp. 53-62
    • Qian, H.1    Zhang, X.2    Xu, W.3
  • 28
    • 84872021754 scopus 로고    scopus 로고
    • Evaluation of healing activity of PVA/chitosan hydrogels on deep second degree burn: Pharmacological and toxicologi-cal tests
    • Nacer Khodja A, Mahlous M, Tahtat D et al. Evaluation of healing activity of PVA/chitosan hydrogels on deep second degree burn: Pharmacological and toxicologi-cal tests. Burns 2013;39:98–104.
    • (2013) Burns , vol.39 , pp. 98-104
    • Nacer Khodja, A.1    Mahlous, M.2    Tahtat, D.3
  • 29
    • 84931578273 scopus 로고    scopus 로고
    • Stem Cells 2014 in press
    • Zhang B, Wang M, Gong A et al. HucMSC-exosome mediated -Wnt4 signaling is required for cutaneous wound healing. Stem Cells 2014 in press.
    • Hucmsc-
    • Zhang, B.1    Wang, M.2    Gong, A.3
  • 30
    • 34147171490 scopus 로고    scopus 로고
    • Endothelial cell migration during angiogenesis
    • Lamalice L, LeBoeuf F, Huot J. Endothelial cell migration during angiogenesis. Circ Res 2007;100:782–794.
    • (2007) Circ Res , vol.100 , pp. 782-794
    • Lamalice, L.1    Leboeuf, F.2    Huot, J.3
  • 32
    • 84877108215 scopus 로고    scopus 로고
    • Wnt signaling in the vasculature
    • Reis M, Liebner S. Wnt signaling in the vasculature. Exp Cell Res 2013;319:1317–1323.
    • (2013) Exp Cell Res , vol.319 , pp. 1323
    • Reis, M.1    Liebner, S.2
  • 33
    • 84903702539 scopus 로고    scopus 로고
    • Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer
    • Pate KT, Stringari C, Sprowl-Tanio S et al. Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer. EMBO J 2014;33:1454–1473.
    • (2014) EMBO J , vol.33 , pp. 1454-1473
    • Pate, K.T.1    Stringari, C.2    Sprowl-Tanio, S.3
  • 34
    • 84871563123 scopus 로고    scopus 로고
    • Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
    • Luga V, Zhang L, Viloria-Petit AM et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell 2012;151:1542–1556.
    • (2012) Cell , vol.151 , pp. 1542-1556
    • Luga, V.1    Zhang, L.2    Viloria-Petit, A.M.3
  • 35
    • 84867101024 scopus 로고    scopus 로고
    • Active Wnt proteins are secreted on exo-somes
    • Gross JC, Chaudhary V, Bartscherer K et al. Active Wnt proteins are secreted on exo-somes. Nat Cell Biol 2012;14:1036–1045.
    • (2012) Nat Cell Biol , vol.14 , pp. 1036-1045
    • Gross, J.C.1    Chaudhary, V.2    Bartscherer, K.3
  • 36
    • 78650977193 scopus 로고    scopus 로고
    • Hepatocytegrowth factor modification promotes the amelioration effects of human umbilical cord mes-enchymal stem cells on rat acute kidney injury
    • Chen Y, Qian H, Zhu W et al. Hepatocyte growth factor modification promotes the amelioration effects of human umbilical cord mes-enchymal stem cells on rat acute kidney injury. Stem Cells Dev 2011;20:103–113.
    • (2011) Stem Cells Dev , vol.20 , pp. 103-113
    • Chen, Y.1    Qian, H.2    Zhu, W.3
  • 37
    • 84879831533 scopus 로고    scopus 로고
    • Human
    • Ma XL, Liu KD, Li FC et al. Human mesenchymal stem cells increases expression ofa-tubulinand angiopoietin1and2infocalce-rebral ischemia and reperfusion. Curr Neuro-vasc Res 2013;10:103–111.
    • (2013) Curr Neuro-Vasc Res , vol.10 , pp. 103-111
    • Ma, X.L.1    Liu, K.D.2    Li, F.C.3
  • 38
    • 84882694765 scopus 로고    scopus 로고
    • Placenta mesen-chymal stem cell accelerates wound healing by enhancing angiogenesis in diabetic Goto-Kakizaki (GK) rats
    • Kong P, Xie X, Li F et al. Placenta mesen-chymal stem cell accelerates wound healing by enhancing angiogenesis in diabetic Goto-Kakizaki (GK) rats. Biochem Biophys Res Com-mun 2013;438:410–419.
    • (2013) Biochem Biophys Res Com-Mun , vol.438 , pp. 410-419
    • Kong, P.1    Xie, X.2    Li, F.3
  • 39
    • 84876940032 scopus 로고    scopus 로고
    • Adipose-derived stem cells promote an-giogenesis and tissue formation for in vivo tissue engineering
    • Matsuda K, Falkenberg KJ, Woods AA et al. Adipose-derived stem cells promote an-giogenesis and tissue formation for in vivo tissue engineering. Tissue Eng Part A 2013;19: 1327–1335.
    • (2013) Tissue Eng Part A , vol.19 , pp. 1327-1335
    • Matsuda, K.1    Falkenberg, K.J.2    Woods, A.A.3
  • 40
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arte-riogenesis through paracrine mechanisms
    • Kinnaird T, Stabile E, Burnett MS et al. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arte-riogenesis through paracrine mechanisms. Circ Res 2004;94:678–685.
    • (2004) Circ Res , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3
  • 41
    • 67949097489 scopus 로고    scopus 로고
    • Exosomes—vesicularcarriers for intercellular communication
    • Simons M, Raposo G. Exosomes—vesicular carriers for intercellular communication. Curr Opin Cell Biol 2009;21:575–581.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 575-581
    • Simons, M.1    Raposo, G.2
  • 42
    • 3142630225 scopus 로고    scopus 로고
    • Exosomes:
    • Février B, Raposo G. Exosomes: Endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol 2004;16: 415–421.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 415-421
    • Février, B.1    Raposo, G.2
  • 43
    • 34948834742 scopus 로고    scopus 로고
    • Endothelial progenitor cell derived micro-vesicles activate an angiogenic program in en-dothelial cells by a horizontal transfer of mRNA
    • Deregibus MC, Cantaluppi V, Calogero R et al. Endothelial progenitor cell derived micro-vesicles activate an angiogenic program in en-dothelial cells by a horizontal transfer of mRNA. Blood 2007;110:2440–2448.
    • (2007) Blood , vol.110 , pp. 2440-2448
    • Deregibus, M.C.1    Cantaluppi, V.2    Calogero, R.3
  • 44
    • 84865311566 scopus 로고    scopus 로고
    • Human liver stem cell-derived microvesicles inhibit hepatoma growth in SCID mice by delivering antitumor microRNAs
    • Fonsato V, Collino F, Herrera MB et al. Human liver stem cell-derived microvesicles inhibit hepatoma growth in SCID mice by delivering antitumor microRNAs. Stem Cells 2012;30:1985–1998.
    • (2012) Stem Cells , vol.30 , pp. 1985-1998
    • Fonsato, V.1    Collino, F.2    Herrera, M.B.3
  • 45
    • 34249302620 scopus 로고    scopus 로고
    • Ekstro¨m K, Bossios A et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, Ekstro¨m K, Bossios A et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007;9: 654–659.
    • (2007) Nat Cell Biol , vol.9 , pp. 654-659
    • Valadi, H.1
  • 46
    • 39749162770 scopus 로고    scopus 로고
    • The
    • Vella LJ, Sharples RA, Nisbet RM et al. The role of exosomes in the processing of proteins associated with neurodegenerative diseases. Eur Biophys J 2008;37:323–332.
    • (2008) Eur Biophys J , vol.37 , pp. 323-332
    • Vella, L.J.1    Sharples, R.A.2    Nisbet, R.M.3
  • 47
    • 84857499728 scopus 로고    scopus 로고
    • Role ofexosomes released by chronic myelogenous leukemia cells in angiogenesis
    • Taverna S, Flugy A, Saieva L et al. Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis. Int J Cancer 2012;130:2033–2043.
    • (2012) Int J Cancer , vol.130 , pp. 2033-2043
    • Taverna, S.1    Flugy, A.2    Saieva, L.3
  • 48
    • 77958555989 scopus 로고    scopus 로고
    • Microparticles carrying Sonic hedgehog favor neovascularization through the activation of nitric oxide pathway in mice
    • Benameur T, Soleti R, Porro C et al. Microparticles carrying Sonic hedgehog favor neovascularization through the activation of nitric oxide pathway in mice. PLoS One 2010; 5:e12688.
    • (2010) Plos One , vol.5
    • Benameur, T.1    Soleti, R.2    Porro, C.3
  • 49
    • 84863231848 scopus 로고    scopus 로고
    • Hsp20 functions as a novel cardiokine in promoting angio-genesis via activation of VEGFR2
    • Zhang X, Wang X, Zhu H et al. Hsp20 functions as a novel cardiokine in promoting angio-genesis via activation of VEGFR2. PLoS One 2012;7:e32765.
    • (2012) Plos One , vol.7
    • Zhang, X.1    Wang, X.2    Zhu, H.3
  • 50
    • 84890149349 scopus 로고    scopus 로고
    • Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles
    • Menck K, Klemm F, Gross JC et al. Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles. Oncotarget 2013;4:2057–2066.
    • (2013) Oncotarget , vol.4 , pp. 2057-2066
    • Menck, K.1    Klemm, F.2    Gross, J.C.3
  • 51
    • 84863933857 scopus 로고    scopus 로고
    • Wnt proteins
    • a007864
    • Willert K, Nusse R. Wnt proteins. Cold Spring Harb Perspect Biol 2012;4:a007864.
    • (2012) Cold , vol.4
    • Willert, K.1    Nusse, R.2
  • 52
    • 18344378499 scopus 로고    scopus 로고
    • Lipo-protein particles are required for Hedgehog and Wingless signalling
    • Panáková D, Sprong H, Marois E et al. Lipo-protein particles are required for Hedgehog and Wingless signalling. Nature 2005;435:58–65.
    • (2005) Nature , vol.435 , pp. 58-65
    • Panáková, D.1    Sprong, H.2    Marois, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.