Hijacking the Cellular Mail: Exosome Mediated Differentiation of Mesenchymal Stem Cells

Stem Cells International

Volumn 2016, Issue , 2016, Pages

  Narayanan, Raghuvaran ^a   Huang, Chun Chieh ^a   Ravindran, Sriram ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 9; COLLAGEN TYPE 1; FIBRONECTIN; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; BONE MARROW STROMA CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL SPECIFICITY; CONTROLLED STUDY; CULTURE TECHNIQUE; ENDOCYTOSIS; EXOSOME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROOSTEOGENIC EXOSOME; PROTEIN BINDING; THREE DIMENSIONAL CELL CULTURE; THREE DIMENSIONAL SCAFFOLD; TISSUE SCAFFOLD; TWO DIMENSIONAL CELL CULTURE;

EID: 84955605332     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2016/3808674     Document Type: Article

References (25)

1. S. Ravindran, Q. Gao, M. Kotecha et al., "Biomimetic extracellular matrix-incorporated scafold induces osteogenic gene expression in human marrow stromal cells, " Tissue Engineering Part A, vol. 18, no. 3-4, pp. 295-309, 2012.
2. S. Ravindran, C.-C. Huang, and A. George, "Extracellular matrix of dental pulp stem cells: applications in pulp tissue engineering using somatic MSCs, " Frontiers in Physiology, vol. 4, article 395, 2014.
3. S. Ravindran, Y. Zhang, C.-C. Huang, and A. George, "Odon-togenic induction of dental stem cells by extracellular matrix-inspired three-dimensional scafold, " Tissue Engineering Part A, vol. 20, no. 1-2, pp. 92-102, 2014.
4. V.K.Gangaraju andH.Lin, "MicroRNAs: key regulatorsofstem cells, " Nature Reviews Molecular Cell Biology, vol. 10, no. 2, pp. 116-125, 2009.
5. R. Yi and E. Fuchs, "MicroRNAs and their roles in mammalian stem cells, " Journal of Cell Science, vol. 124, no. 11, pp. 1775-1783, 2011.
6. Y. Zhang, Z. Wang, and R. A. Gemeinhart, "Progress in microRNA delivery, " Journal of Controlled Release, vol. 172, no. 3, pp. 962-974, 2013.
7. B. Yu, X. Zhang, and X. Li, "Exosomes derived from mesenchy-mal stem cells, " International Journal of Molecular Sciences, vol. 15, no. 3, pp. 4142-4157, 2014.
8. K. J. Svensson, H. C. Christianson, A. Wittrup et al., "Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid raf-mediated endocytosis negatively regulated by caveolin-1, " The Journal of Biological Chemistry, vol. 288, no. 24, pp. 17713-17724, 2013.
9. R. Wang, M. Lin, L. Li et al., "Bone marrow mesenchymal stem cell-derived exosome protects kidney against ischemia reperfusion injury in rats, " Zhonghua Yi Xue Za Zhi, vol. 94, pp. 3298-3303, 2014.
10. J. Zhang, J. Guan, X. Niu et al., "Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis, " Journal of Translational Medicine, vol. 13, article 49, 2015.
11. Y. Zhang, M. Chopp, Y. Meng et al., "Efect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats afer traumatic brain injury, " Journal of Neurosurgery, vol. 122, no. 4, pp. 856-867, 2015.
12. R. Blazquez, F. M. Sanchez-Margallo, O. de la Rosa et al., "Immunomodulatory potential of human adipose mesenchy-mal stem cells derived exosomes on in vitro stimulated T cells, " Frontiers in Immunology, vol. 5, article 556, 2014.
13. J.-F. Xu, G.-H. Yang, X.-H. Pan et al., "Altered microRNA expression profle in exosomes during osteogenic diferentia-tion of human bone marrow-derived mesenchymal stem cells, " PLoS ONE, vol. 9, no. 12, Article ID e114627, 2014.
14. J. G. van den Boorn, M. Schlee, C. Coch, and G. Hartmann, "SiRNA delivery with exosome nanoparticles, " Nature Biotechnology, vol. 29, no. 4, pp. 325-326, 2011.
15. T. Tian, Y.-L. Zhu, Y.-Y. Zhou et al., "Exosome uptake through clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 delivery, " The Journal of Biological Chemistry, vol. 289, no. 32, pp. 22258-22267, 2014.
16. S. Ravindran, Q. Gao, A. Ramachandran, S. Blond, S. A. Predescu, and A. George, "Stress chaperone GRP-78 functions in mineralized matrix formation, " The Journal of Biological Chemistry, vol. 286, no. 11, pp. 8729-8739, 2011.
17. C. Escrevente, S. Keller, P. Altevogt, and J. Costa, "Interaction and uptake of exosomes by ovarian cancer cells, " BMC Cancer, vol. 11, article 108, 2011.
18. G. Luther, E. R. Wagner, G. Zhu et al., "BMP-9 induced osteogenic diferentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential, " Current Gene Ter-apy, vol. 11, no. 3, pp. 229-240, 2011.
19. L. Zhao, S. Jiang, and B. M. Hantash, "Transforming growth factor?1 induces osteogenic diferentiation of murine bone marrow stromal cells, " Tissue Engineering Part A, vol. 16, no. 2, pp. 725-733, 2010.
20. J. D. Lamplot, J. Qin, G. Nan et al., "BMP9 signaling in stem cell diferentiation and osteogenesis, " American Journal of Stem Cells, vol. 2, pp. 1-21, 2013.
21. J. T. Marino and B. H. Ziran, "Use of solid and cancellous autol-ogous bone graf for fractures and nonunions, " The Orthopedic Clinics of North America, vol. 41, no. 1, pp. 15-26, 2010.
22. P. A. Zuk, "Tissue engineering craniofacial defects with adult stem cells? Are we ready yet?" Pediatric Research, vol. 63, no. 5, pp. 478-486, 2008.
23. J. N. Zara, R. K. Siu, X. Zhang et al., "High doses of bone morphogenetic protein 2 induce structurally abnormal bone and infammation in vivo, " Tissue Engineering Part A, vol. 17, no. 9-10, pp. 1389-1399, 2011.
24. C. A. Tannoury and H. S. An, "Complications with the use of bone morphogenetic protein 2 (BMP-2) in spine surgery, " The Spine Journal, vol. 14, no. 3, pp. 552-559, 2014.
25. O. G. De Jong, B. W. M. Van Balkom, R. M. Schifelers, C. V. C. Bouten, and M. C. Verhaar, "Extracellular vesicles: potential roles in regenerative medicine, " Frontiers in Immunology, vol. 5, article 608, 2014.