Intermittent hypoxia impairs endothelial function in early preatherosclerosis

Advances in Experimental Medicine and Biology

Volumn 858, Issue , 2015, Pages 1-7

  Tuleta, I ^a   Franca C N ^a   Wenzel, D ^a   Fleischmann, B ^a   Nickenig, G ^a   Werner, N ^a   Skowasch, D ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Breathing disorder; Compensatory mechanisms; Endothelial damage; Endothelial precursor cells; Endothelium dependent vasorelaxation; Hypoxia reoxygenation

Indexed keywords

ATAXIN 1; CD31 ANTIGEN; LIPOCORTIN 5; VASCULOTROPIN RECEPTOR 2; APOLIPOPROTEIN E; CHOLESTEROL; LY ANTIGEN; LY6A PROTEIN, MOUSE; MEMBRANE PROTEIN; PHENYLEPHRINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BONE MARROW; CELL COUNT; CELL SELECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIAL MICROPARTICLE; ENDOTHELIAL PROGENITOR CELL; FEMALE; FLOW CYTOMETRY; INTERMITTENT HYPOXIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SLEEP DISORDERED BREATHING; ANIMAL; ANOXIA; CHEMISTRY; COMPLICATION; DEFICIENCY; DRUG EFFECTS; ENDOTHELIUM CELL; GENE EXPRESSION; GENETICS; KNOCKOUT MOUSE; LIPID DIET; MEMBRANE MICROPARTICLE; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; STEM CELL; THORACIC AORTA; TIME; VASCULAR ENDOTHELIUM; VASOCONSTRICTION;

MUS;

ANIMALS; ANNEXIN A5; ANOXIA; ANTIGENS, CD31; ANTIGENS, LY; AORTA, THORACIC; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CELL-DERIVED MICROPARTICLES; CHOLESTEROL; DIET, HIGH-FAT; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; GENE EXPRESSION; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; ORGAN CULTURE TECHNIQUES; PHENYLEPHRINE; SLEEP APNEA, OBSTRUCTIVE; STEM CELLS; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; VASOCONSTRICTION;

EID: 84938519097     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/5584_2015_114     Document Type: Article

References (17)

1. Akinnusi ME, El Solh AA (2009) Circulating endothelial microparticle levels and hemodynamic severity of pulmonary hypertension: is there a role for sleep apnea? Am J Respir Crit Care Med 179:328
2. Ayers L, Ferry B, Craig S, Nicoll D, Stradling JR, Kohler M (2009) Circulating cell-derived microparticles in patients with minimally symptomatic obstructive sleep apnoea. Eur Respir J 33:574–580
3. Dematteis M, Julien C, Guillermet C, Sturm N, Lantuejoul S, Mallaret M, Lévy P, Gozal E (2008) Intermittent hypoxia induces early functional cardiovascular remodeling in mice. Am J Respir Crit Care Med 177:227–235
4. Faulx MD, Larkin EK, Hoit BD, Aylor JE, Wright AT, Redline S (2004) Sex influences endothelial function in sleep-disordered breathing. Sleep 27:1113–1120
5. Hernóndez-Guerra M, de Ganzo ZA, Gonzólez- Méndez Y, Salido E, Abreu P, Moreno M, Felipe V, Abrante B, Quintero E (2013) Chronic intermittent hypoxia aggravates intrahepatic endothelial dysfunction in cirrhotic rats. Hepatology 57:1564–1574
6. Ip MS, Tse HF, Lam B, Tsang KW, Lam WK (2004) Endothelial function in obstructive sleep apnea and response to treatment. Am J Respir Crit Care Med 169:348–353
7. Jelic S, Padeletti M, Kawut SM, Higgins C, Canfield SM, Onat D, Colombo PC, Basner RC, Factor P, LeJemtel TH (2008) Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea. Circulation 117:2270–2278
8. Jelic S, Lederer DJ, Adams T (2009) Endothelial repair capacity and apoptosis are inversely related in obstructive sleep apnea. Vasc Health Risk Manag 5:909–920
9. Jun J, Reinke C, Bedja D, Berkowitz D, Bevans-Fonti S, Li J, Barouch LA, Gabrielson K, Polotsky VY (2010) Effect of intermittent hypoxia on atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis 209:381–386
10. Kizawa T, Nakamura Y, Takahashi S, Sakurai S, Yamauchi K, Inoue H (2009) Pathogenic role of angiotensin II and oxidized LDL in obstructive sleep apnoea. Eur Respir J 34:1390–1398
11. Marshall NS, Wong KK, Liu PY, Cullen SR, Knuiman MW, Grunstein RR (2008) Sleep apnea as an independent risk factor for all-cause mortality: the Busselton health study. Sleep 31:1079–1085
12. Namtvedt SK, Hisdal J, Randby A, Agewall S, Stranden E, Somers VK, Røsjø H, Omland T (2013) Impaired endothelial function in persons with obstructive sleep apnoea: impact of obesity. Heart 99:30–34
13. National Research Council (1996) 8(22):25–27
14. Phillips SA, Olson EB, Morgan BJ, Lombard JH (2004) Chronic intermittent hypoxia impairs endotheliumdependent dilation in rat cerebral and skeletal muscle resistance arteries. Am J Physiol Heart Circ Physiol 286:H388–H393
15. Seif F, Patel SR, Walia H, Rueschman M, Bhatt DL, Gottlieb DJ, Lewis EF, Patil SP, Punjabi NM, Babineau DC, Redline S, Mehra R (2013) Association between obstructive sleep apnea severity and endothelial dysfunction in an increased background of cardiovascular burden. J Sleep Res 22:443–451
16. Tuleta I, Franc¸a CN, Wenzel D, Fleischmann B, Nickenig G, Werner N, Skowasch D (2014) Hypoxia-induced endothelial dysfunction in apolipoprotein E-deficient mice; effects of infliximab and l-glutathione. Atherosclerosis 236:400–410
17. Yeboah J, Crouse JR, Hsu FC, Burke GL, Herrington DM (2007) Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the cardiovascular health study. Circulation 115:2390–2397