Endothelium-derived microparticles impair endothelial function in vitro

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 286, Issue 5 55-5, 2004, Pages

  Brodsky, Sergey V ^a,b   Zhang, Fan ^a   Nasjletti, Alberto ^a   Goligorsky, Michael S ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b RENAL RESEARCH INSTITUTE   (United States)

Author keywords

Cardiovascular disease; Cell dysfunction; Nitric oxide; Superoxide

Indexed keywords

ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PORPHYRIN DERIVATIVE; PROTEIN P22; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; IN VITRO STUDY; INHIBITION KINETICS; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; AORTA; BLOOD COAGULATION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; MEMBRANE TRANSPORT PROTEINS; METALLOPORPHYRINS; NADPH DEHYDROGENASE; NADPH OXIDASE; PARTICLE SIZE; PHOSPHOPROTEINS; RATS; SUPEROXIDES; VASODILATION;

EID: 1942533438     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01172.2003     Document Type: Article

References (39)

1. Armstrong MJ, Storch J, and Dainiak N. Structurally distinct plasma membrane regions give rise to extracellular membrane vesicles in normal and transformed lymphocytes. Biochim Biophys Acta 946: 106-112, 1988.
2. Barry OP, Pratico D, Savani RC, and FitzGerald GA. Modulation of monocyte-endothelial cell interactions by platelet microparticles. J Clin Invest 102: 136-144, 1998.
3. Berckmans RJ, Neiuwland R, Boing AN, Romijn FP, Hack CE, and Sturk A. Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. Thromb Haemost 85: 639-646, 2001.
4. Boulanger CM, Scoazec A, Ebrahimian T, Henry P, Mathieu E, Tedgui A, and Mallat Z. Circulating microparticles from patients with myocardial infarction cause endothelial dysfunction. Circulation 104: 2649-2652, 2001.
5. Bretelle F, Sabatier F, Desprez D, Camoin L, Grunebaum L, Combes V, D'Ercole C, and Dignat-George F. Circulating microparticles: a marker of procoagulant state in normal pregnancy and pregnancy complicated by preeclampsia or intrauterine growth restriction. Thromb Haemost 89: 486-492, 2003.
6. Brodsky SV, Gao S, Li H, and Goligorsky MS. Hyperglycemic switch from mitochondrial nitric oxide to superoxide production in endothelial cells. Am J Physiol Heart Circ Physiol 283: H2130-H2139, 2002.
7. Brodsky SV, Malinowski K, Golightly M, Jesty J, and Goligorsky MS. Plasminogen activator inhibitor-1 promotes formation of endothelial microparticles with procoagulant potential. Circulation 106: 2372-2378, 2002.
8. Cai H and Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87: 840-844, 2000.
9. Cines DB, Pollak ES, Buck CA, Loscalzo J, Zimmerman GA, McEver RP, Pober JS, Wick TM, Konkle BA, Schwartz BS, Barnathan ES, McCrae KR, Hug BA, Schmidt AM, and Stern DM. Endothelial cell in physiology and in the pathophysiology of vascular disorders. Blood 91: 3527-3561, 1998.
10. Combes V, Simon AC, Grau GE, Arnoux D, Camoin L, Sabatier F, Mutin M, Sanmarco M, Sampol J, and Dignat-George F. In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant. J Clin Invest 104: 93-102, 1999.
11. Furchgott RF and Zawadzki JW. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376, 1980.
12. Garg UC and Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 83: 1774-1777, 1989.
13. Gasser O, Hess C, Miot S, Deon C, Sanchez JC, and Schifferli JJA. Characterisation and properties of ectosomes released by human polymorphonuclear neutrophils. Exp Cell Res 285: 243-257, 2003.
14. George JN, Thoi LL, McManus LM, and Reimann TA. Isolation of human platelet membrane microparticles from plasma and serum. Blood 60: 834-840, 1982.
15. Goligorsky MS, Chen J, and Brodsky SV. Endothelial cell dysfunction leading to diabetic nephropathy-focus on nitric oxide. Hypertension 37: 744-748, 2001.
16. Harrison DG. Endothelial function and oxidant stress. Clin Cardiol 20 Suppl 2: II11-II17, 1997.
17. Jimenez JJ, Jy W, Mauro LM, Horstman LL, and Ahn YS. Elevated endothelial microparticles in thrombotic thrombocytopenic purpura: findings from brain and renal microvascular cell culture and patients with active disease. Br J Haematol 112: 81-90, 2001.
18. Jimenez JJ, Jy W, Mauro LM, Soderland C, Horstman LL, and Ahn YS. Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis. Thromb Res 109: 175-180, 2003.
19. Kuzkaya N, Weissmann N, Harrison DG, and Dikalov S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid and thiols: implications for uncoupling endothelial nitric oxide synthase. J Biol Chem 278: 22546-22554, 2003.
20. Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, and Harrison DG. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest 111: 1201-1209, 2003.
21. Li H, Brodsky S, Kumari S, Valiunas V, Brink P, Kaide J, Nasjletti A, and Goligorsky MS. Paradoxical overexpression and translocation of connexin43 in homocysteine-treated endothelial cells. Am J Physiol Heart Circ Physiol 282: H2124-H2133, 2002.
22. Ludmer PL, Selwyn AP, Shook TL, Wayne RR, Mudge GH, Alexander RW, and Ganz P. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N Engl J Med 315: 1046-1051, 1986.
23. Mack M, Kleinschmidt A, Bruhl H, Klier C, Nelson PJ, Cihak J, Plachy J, Stangassinger M, Erfle V, and Schlondorff D. Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection. Nat Med 6: 769-775, 2000.
24. Mingone CJ, Gupte SA, Quan S, Abraham NG, and Wolin MS. Influence of heme and heme oxygenase-1 transfection of pulmonary microvascular endothelium on oxidant generation and cGMP. Exp Biol Med 228: 535-539, 2003.
25. Nomura S, Suzuki M, Katsura K, Xie GL, Miyazaki Y, Miyake T, Kido H, Kagawa H, and Fukuhara S. Platelet-derived microparticles may influence the development of atherosclerosis in diabetes mellitus. Atherosclerosis 116: 235-240, 1995.
26. Preston RA, Jy W, Jimenez JJ, Mauro LM, Horstman LL, Valle M, Aime G, and Ahn YS. Effects of severe hypertension on endothelial and platelet microparticles. Hypertension 41: 211-217, 2003.
27. Singh N, Gemmell C, Daly P, and Yeo EL. Elevated platelet-derived microparticle levels during unstable angina. Can J Cardiol 11: 1015-1021, 1995.
28. Taraboletti G, D'Ascenzo S, Borsotti P, Giavazzi R, Pavan A, and Dolo V. Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells. Am J Pathol 60: 673-680, 2002.
29. Tsukahara H, Gordienko D, Tonshoff B, Gelato M, and Goligorsky MS. Direct demonstration of insulin-like growth factor-I-induced nitric oxide production by endothelial cells. Kidney Int 45: 598-604, 1994.
30. VanWijk MJ, Boer K, Berckmans RJ, Meijers JC, van der Post JA, Sturk A, VanBavel E, and Nieuwland R. Enhanced coagulation activation in preeclampsia: the role of APC resistance, microparticles and other plasma constituents. Thromb Haemost 88: 415-420, 2002.
31. VanWijk MJ, Nieuwland R, Boer K, van der Post JA, VanBavel E, and Sturk A. Microparticle subpopulations are increased in preeclampsia: possible involvement in vascular dysfunction? Am J Obstet Gynecol 187: 450-456, 2002.
32. VanWijk MJ, Svedas E, Boer K, Nieuwland R, Vanbavel E, and Kublickiene KR. Isolated microparticles, but not whole plasma, from women with preeclampsia impair endothelium-dependent relaxation in isolated myometrial arteries, from healthy pregnant women. Am J Obstet Gynecol 187: 1686-1693, 2002.
33. VanWijk MJ, VanBavel E, Sturk A, and Nieuwland R. Microparticles in cardiovascular diseases. Cardiovasc Res 59: 277-287, 2003.
34. Vasquez-Vivar J, Kalyanaraman B, Martasek P, Hogg N, Masters BS, Karoui H, Tordo P, and Pritchard KA Jr. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA 95: 9220-9225, 1998.
35. Von der Leyen H, Gibbons G, Morishita R, Lewis N, Zhang L, Nakajima M, Kaneda Y, Cooke J, and Dzau VJ. Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. Proc Natl Acad Sci USA 92: 1137-1141, 1995.
36. Wolf P. The nature and significance of platelet products in human plasma. Br J Haematol 3: 269-288, 1967.
37. Zhang X, Li H, Jin H, Ebin Z, Brodsky S, and Goligorsky MS. Effects of homocysteine on endothelial nitric oxide production. Am J Physiol Renal Physiol 279: F671-F678, 2000.
38. Zucker-Franklin D. Clinical significance of platelet microparticles. J Lab Clin Med 119: 321-322, 1992.
39. Zwaal RF and Schroit AJ. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells. Blood 89: 1121-1132, 1997.