-
1
-
-
84942938808
-
Rapid and transient palmitoylation of the tyrosine kinase Lck mediates Fas signaling
-
Akimzhanov AM, Boehning D (2015). Rapid and transient palmitoylation of the tyrosine kinase Lck mediates Fas signaling. Proc Natl Acad Sci USA 112, 11876-11880.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 11876-11880
-
-
Akimzhanov, A.M.1
Boehning, D.2
-
2
-
-
84867713025
-
The p110ä isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock
-
Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno IM, Nock G, Filloux A, et al. (2012). The p110ä isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock. Nat Immunol 13, 1045-1054.
-
(2012)
Nat Immunol
, vol.13
, pp. 1045-1054
-
-
Aksoy, E.1
Taboubi, S.2
Torres, D.3
Delbauve, S.4
Hachani, A.5
Whitehead, M.A.6
Pearce, W.P.7
Berenjeno, I.M.8
Nock, G.9
Filloux, A.10
-
3
-
-
77954470691
-
Functional analysis of Lyn kinase A and B isoforms reveals redundant and distinct roles in Fc epsilon RI-dependent mast cell activation
-
Alvarez-Errico D, Yamashita Y, Suzuki R, Odom S, Furumoto Y, Yamashita T, Rivera J (2010). Functional analysis of Lyn kinase A and B isoforms reveals redundant and distinct roles in Fc epsilon RI-dependent mast cell activation. J Immunol 184, 5000-5008.
-
(2010)
J Immunol
, vol.184
, pp. 5000-5008
-
-
Alvarez-Errico, D.1
Yamashita, Y.2
Suzuki, R.3
Odom, S.4
Furumoto, Y.5
Yamashita, T.6
Rivera, J.7
-
4
-
-
84883076264
-
Severe sepsis and septic shock
-
Angus DC, van der Poll T (2013). Severe sepsis and septic shock. N Engl J Med 369, 840-851.
-
(2013)
N Engl J Med
, vol.369
, pp. 840-851
-
-
Angus, D.C.1
Van Der Poll, T.2
-
5
-
-
84863912331
-
Lyn kinase controls TLR4-dependent IKK and MAPK activation modulating the activity of TRAF-6/TAK-1 protein complex in mast cells
-
Avila M, Martinez-Juarez A, Ibarra-Sanchez A, Gonzalez-Espinosa C (2012). Lyn kinase controls TLR4-dependent IKK and MAPK activation modulating the activity of TRAF-6/TAK-1 protein complex in mast cells. Innate Immun 18, 648-660.
-
(2012)
Innate Immun
, vol.18
, pp. 648-660
-
-
Avila, M.1
Martinez-Juarez, A.2
Ibarra-Sanchez, A.3
Gonzalez-Espinosa, C.4
-
6
-
-
19944362471
-
The induction of macrophage gene expression by LPS predominantly utilizes Myd88- independent signaling cascades
-
Bjorkbacka H, Fitzgerald KA, Huet F, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW (2004). The induction of macrophage gene expression by LPS predominantly utilizes Myd88- independent signaling cascades. Physiol Genomics 19, 319-330.
-
(2004)
Physiol Genomics
, vol.19
, pp. 319-330
-
-
Bjorkbacka, H.1
Fitzgerald, K.A.2
Huet, F.3
Gregory, J.A.4
Lee, M.A.5
Ordija, C.M.6
Dowley, N.E.7
Golenbock, D.T.8
Freeman, M.W.9
-
7
-
-
84896374384
-
CD14 mediates binding of high doses of LPS but is dispensable for TNF-α production
-
Borzecka K, Plociennikowska A, Bjorkelund H, Sobota A, Kwiatkowska K (2013). CD14 mediates binding of high doses of LPS but is dispensable for TNF-α production. Mediators Inflamm 2013, 824919.
-
(2013)
Mediators Inflamm
, vol.2013
, pp. 824919
-
-
Borzecka, K.1
Plociennikowska, A.2
Bjorkelund, H.3
Sobota, A.4
Kwiatkowska, K.5
-
8
-
-
43549086881
-
Isolation and use of rafts
-
Unit 11.10
-
Brown DA (2002). Isolation and use of rafts. Curr Protoc Immunol Chapter 11, Unit 11.10.
-
(2002)
Curr Protoc Immunol Chapter
, vol.11
-
-
Brown, D.A.1
-
9
-
-
84895509356
-
The role of TLR2, TLR4 and CD36 in macrophage activation and foam cell formation in response to oxLDL in humans
-
Chavez-Sanchez L, Garza-Reyes MG, Espinosa-Luna JE, Chávez-Rueda K, Legorreta-Haquet MV, Blanco-Favela F (2014). The role of TLR2, TLR4 and CD36 in macrophage activation and foam cell formation in response to oxLDL in humans. Hum Immunol 75, 322-329.
-
(2014)
Hum Immunol
, vol.75
, pp. 322-329
-
-
Chavez-Sanchez, L.1
Garza-Reyes, M.G.2
Espinosa-Luna, J.E.3
Chávez-Rueda, K.4
Legorreta-Haquet, M.V.5
Blanco-Favela, F.6
-
10
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex transfer from CD14 to TLR4 and MD-2
-
Da Silva Correia J, Soldau K, Christen U, Tobias PS, Ulevitch RJ (2001). Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex transfer from CD14 to TLR4 and MD-2. J Biol Chem 276, 21129-21135.
-
(2001)
J Biol Chem
, vol.276
, pp. 21129-21135
-
-
Da Silva Correia, J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
11
-
-
84884237993
-
Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate
-
Davda D, El Azzouny MA, Tom CT, Hernandez J L, Majmudar JD, Kennedy RT, Martin BR (2013). Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate. ACS Chem Biol 8, 1912-1917.
-
(2013)
ACS Chem Biol
, vol.8
, pp. 1912-1917
-
-
Davda, D.1
El Azzouny, M.A.2
Tom, C.T.3
Hernandez, J.L.4
Majmudar, J.D.5
Kennedy, R.T.6
Martin, B.R.7
-
12
-
-
0031456722
-
Bacterial LPS and IFN - Ã trigger the tyrosine phosphorylation of vav in macrophages: Evidence for involvement of the hck tyrosine kinase
-
English BK, Orlicek SL, Mei Z, Meals EA (1997). Bacterial LPS and IFN-ã trigger the tyrosine phosphorylation of vav in macrophages: evidence for involvement of the hck tyrosine kinase. J Leukoc Biol 62, 859-864.
-
(1997)
J Leukoc Biol
, vol.62
, pp. 859-864
-
-
English, B.K.1
Orlicek, S.L.2
Mei, Z.3
Meals, E.A.4
-
13
-
-
84946605555
-
Lyn A regulates an inflammation-sensitive signaling checkpoint in macrophages
-
Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A (2015). Lyn A regulates an inflammation-sensitive signaling checkpoint in macrophages. Elife 4, e09183.
-
(2015)
Elife
, vol.4
, pp. e09183
-
-
Freedman, T.S.1
Tan, Y.X.2
Skrzypczynska, K.M.3
Manz, B.N.4
Sjaastad, F.V.5
Goodridge, H.S.6
Lowell, C.A.7
Weiss, A.8
-
14
-
-
19044393483
-
Monomeric endotoxin:protein complexes are essential for TLR4-dependent cell activation
-
Gioannini TL, Teghanemt A, Zhang D, Levis EN, Weiss JP (2005). Monomeric endotoxin:protein complexes are essential for TLR4-dependent cell activation. J Endotoxin Res 11, 117-123.
-
(2005)
J Endotoxin Res
, vol.11
, pp. 117-123
-
-
Gioannini, T.L.1
Teghanemt, A.2
Zhang, D.3
Levis, E.N.4
Weiss, J.P.5
-
15
-
-
69249222576
-
Roles for SH2 and SH3 domains in Lyn kinase association with activated FcϵRI in RBL mast cells revealed by patterned surface analysis
-
Hammond S, Wagenknecht-Wiesner A, Veatch SL, Holowka D, Baird B (2009). Roles for SH2 and SH3 domains in Lyn kinase association with activated FcϵRI in RBL mast cells revealed by patterned surface analysis. J Struct Biol 168, 161-167.
-
(2009)
J Struct Biol
, vol.168
, pp. 161-167
-
-
Hammond, S.1
Wagenknecht-Wiesner, A.2
Veatch, S.L.3
Holowka, D.4
Baird, B.5
-
16
-
-
17944381147
-
Gain- and loss-offunction Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage
-
Harder KW, Parsons LM, Armes J, Evans N, Kountouri N, Clark R, Quilici C, Grail D, Hodgson GS, Dunn AR, Hibbs ML (2001). Gain- and loss-offunction Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage. Immunity 15, 603-615.
-
(2001)
Immunity
, vol.15
, pp. 603-615
-
-
Harder, K.W.1
Parsons, L.M.2
Armes, J.3
Evans, N.4
Kountouri, N.5
Clark, R.6
Quilici, C.7
Grail, D.8
Hodgson, G.S.9
Dunn, A.R.10
Hibbs, M.L.11
-
17
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng T, Barton GM, Flavell RA, Medzhitov R (2002). The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 420, 329-333.
-
(2002)
Nature
, vol.420
, pp. 329-333
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
18
-
-
0038544296
-
Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor α production
-
Horwood NJ, Mahon T, McDaid JP, Campbell J, Mano H, Brennan FM, Webster D, Foxwell BM (2003). Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor α production. J Exp Med 197, 1603-1611.
-
(2003)
J Exp Med
, vol.197
, pp. 1603-1611
-
-
Horwood, N.J.1
Mahon, T.2
McDaid, J.P.3
Campbell, J.4
Mano, H.5
Brennan, F.M.6
Webster, D.7
Foxwell, B.M.8
-
19
-
-
84921815877
-
PAG - A multipurpose transmembrane adaptor protein
-
Hrdinka M, Horejsi V (2014). PAG-a multipurpose transmembrane adaptor protein. Oncogene 33, 4881-4892.
-
(2014)
Oncogene
, vol.33
, pp. 4881-4892
-
-
Hrdinka, M.1
Horejsi, V.2
-
20
-
-
33644508366
-
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
-
Husebye H, Halaas O, Stenmark H, Tunheim G, Sandanger O, Bogen B, Brech A, Latz E, Espevik T (2006). Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO J 25, 683-692.
-
(2006)
EMBO J
, vol.25
, pp. 683-692
-
-
Husebye, H.1
Halaas, O.2
Stenmark, H.3
Tunheim, G.4
Sandanger, O.5
Bogen, B.6
Brech, A.7
Latz, E.8
Espevik, T.9
-
21
-
-
69949106681
-
Requirement of the SH4 and tyrosine-kinase domains but not the kinase activity of Lyn for its biosynthetic targeting to caveolin-positive Golgi membranes
-
Ikeda K, Nakayama Y, Ishii M, Obata Y, Kasahara K, Fukumoto Y, Yamaguchi N (2009). Requirement of the SH4 and tyrosine-kinase domains but not the kinase activity of Lyn for its biosynthetic targeting to caveolin-positive Golgi membranes. Biochim Biophys Acta 1790, 1345-1352.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1345-1352
-
-
Ikeda, K.1
Nakayama, Y.2
Ishii, M.3
Obata, Y.4
Kasahara, K.5
Fukumoto, Y.6
Yamaguchi, N.7
-
22
-
-
0037079737
-
Tyrosine phosphorylation of B-cell adaptor for phosphoinositide 3-kinase is required for Akt activation in response to CD19 engagement
-
Inabe K, Kurosaki T (2002). Tyrosine phosphorylation of B-cell adaptor for phosphoinositide 3-kinase is required for Akt activation in response to CD19 engagement. Blood 99, 584-589.
-
(2002)
Blood
, vol.99
, pp. 584-589
-
-
Inabe, K.1
Kurosaki, T.2
-
23
-
-
38349014380
-
Src family kinases: Regulation of their activities, levels and identification of new pathways
-
Ingley E (2008). Src family kinases: regulation of their activities, levels and identification of new pathways. Biochim Biophys Acta 1784, 56-65.
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 56-65
-
-
Ingley, E.1
-
24
-
-
84865098491
-
Functions of the Lyn tyrosine kinase in health and disease
-
Ingley E (2012). Functions of the Lyn tyrosine kinase in health and disease. Cell Commun Signal 10, 21.
-
(2012)
Cell Commun Signal
, vol.10
, pp. 21
-
-
Ingley, E.1
-
25
-
-
33646908228
-
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
-
Kagan JC, Medzhitov R (2006). Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125, 943-955.
-
(2006)
Cell
, vol.125
, pp. 943-955
-
-
Kagan, J.C.1
Medzhitov, R.2
-
26
-
-
40949134086
-
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
-
Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R (2008). TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β. Nat Immunol 9, 361-368.
-
(2008)
Nat Immunol
, vol.9
, pp. 361-368
-
-
Kagan, J.C.1
Su, T.2
Horng, T.3
Chow, A.4
Akira, S.5
Medzhitov, R.6
-
27
-
-
79956300649
-
Toll-Like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T, Akira S (2011). Toll-Like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34, 637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
28
-
-
77954709866
-
Activation of murine macrophages via TLR2 and TLR4 is negatively regulated by a Lyn/PI3K module and promoted by SHIP1
-
Keck S, Freudenberg M, Huber M (2010). Activation of murine macrophages via TLR2 and TLR4 is negatively regulated by a Lyn/PI3K module and promoted by SHIP1. J Immunol 184, 5809-5818.
-
(2010)
J Immunol
, vol.184
, pp. 5809-5818
-
-
Keck, S.1
Freudenberg, M.2
Huber, M.3
-
29
-
-
84937969167
-
The role of TLR4 and Fyn interaction on lipopolysaccharide-stimulated PAI-1 expression in astrocytes
-
Ko HM, Lee SH, Kim KC, Joo SH, Choi WS, Shin CY (2015). The role of TLR4 and Fyn interaction on lipopolysaccharide-stimulated PAI-1 expression in astrocytes. Mol Neurobiol 52, 8-25.
-
(2015)
Mol Neurobiol
, vol.52
, pp. 8-25
-
-
Ko, H.M.1
Lee, S.H.2
Kim, K.C.3
Joo, S.H.4
Choi, W.S.5
Shin, C.Y.6
-
30
-
-
0035197895
-
Structure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcϵ receptor i aggregation
-
Kovarova M, Tolar P, Arudchandran R, Draberova L, Rivera J, Draber P (2001). Structure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcϵ receptor I aggregation. Mol Cell Biol 21, 8318-8328.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8318-8328
-
-
Kovarova, M.1
Tolar, P.2
Arudchandran, R.3
Draberova, L.4
Rivera, J.5
Draber, P.6
-
31
-
-
0037328967
-
Phosphorylation of FcγRIIA is required for the receptor-induced actin rearrangement and capping, the role of membrane rafts
-
Kwiatkowska K, Frey J, Sobota A (2003). Phosphorylation of FcγRIIA is required for the receptor-induced actin rearrangement and capping, the role of membrane rafts. J Cell Sci 116, 537-550.
-
(2003)
J Cell Sci
, vol.116
, pp. 537-550
-
-
Kwiatkowska, K.1
Frey, J.2
Sobota, A.3
-
32
-
-
74849118341
-
Lipid rafts as a membrane-organizing principle
-
Lingwood D, Simons K (2010). Lipid rafts as a membrane-organizing principle. Science 327, 46-50.
-
(2010)
Science
, vol.327
, pp. 46-50
-
-
Lingwood, D.1
Simons, K.2
-
33
-
-
81055144100
-
Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: Signaling cross talk
-
Lowell CA (2011). Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talk. Cold Spring Harb Perspect Biol 3, a002352.
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
, pp. a002352
-
-
Lowell, C.A.1
-
34
-
-
33646829136
-
TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling
-
Lu G, Kang YJ, Han J, Herschman HR, Stefani E, Wang Y (2006). TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling. J Biol Chem 281, 6087-6095.
-
(2006)
J Biol Chem
, vol.281
, pp. 6087-6095
-
-
Lu, G.1
Kang, Y.J.2
Han, J.3
Herschman, H.R.4
Stefani, E.5
Wang, Y.6
-
35
-
-
34447525018
-
Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance
-
Medvedev AE, Piao W, Shoenfelt J, Rhee SH, Chen H, Basu S, Wahl LM, Fenton MJ, Vogel SN (2007). Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance. J Biol Chem 282, 16042-16053.
-
(2007)
J Biol Chem
, vol.282
, pp. 16042-16053
-
-
Medvedev, A.E.1
Piao, W.2
Shoenfelt, J.3
Rhee, S.H.4
Chen, H.5
Basu, S.6
Wahl, L.M.7
Fenton, M.J.8
Vogel, S.N.9
-
36
-
-
84871860548
-
Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia
-
Moreira AP, Texeira TF, Ferreira AB, Peluzio Mdo C, Alfenas Rde C (2012). Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia. Br J Nutr 108, 801-809.
-
(2012)
Br J Nutr
, vol.108
, pp. 801-809
-
-
Moreira, A.P.1
Texeira, T.F.2
Ferreira, A.B.3
Peluzio Mdo, C.4
Alfenas Rde, C.5
-
37
-
-
69949161905
-
An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4
-
Motshwene PG, Moncrieffe MC, Grossmann JG, Kao C, Ayaluru M, Sandercock A M, Carol V, Robinson C, Latz E, Gay NJ (2009). An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4. J Biol Chem 284, 25404-25411.
-
(2009)
J Biol Chem
, vol.284
, pp. 25404-25411
-
-
Motshwene, P.G.1
Moncrieffe, M.C.2
Grossmann, J.G.3
Kao, C.4
Ayaluru, M.5
Sandercock, A.M.6
Carol, V.7
Robinson, C.8
Latz, E.9
Gay, N.J.10
-
38
-
-
84855992592
-
B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K
-
Ni M, MacFarlane AW 4th, Toft M, Lowell CA, Campbell KS, Hamerman JA (2012). B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K. Proc Natl Acad Sci USA 109, 267-272.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 267-272
-
-
Ni, M.1
MacFarlane, I.V.A.W.2
Toft, M.3
Lowell, C.A.4
Campbell, K.S.5
Hamerman, J.A.6
-
39
-
-
33646830442
-
Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins
-
Ohno Y, Kihara A, Sano T, Igarashi Y (2006). Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. Biochim Biophys Acta 1761, 474-483.
-
(2006)
Biochim Biophys Acta
, vol.1761
, pp. 474-483
-
-
Ohno, Y.1
Kihara, A.2
Sano, T.3
Igarashi, Y.4
-
40
-
-
50949130076
-
Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharideinduced interleukin-12 production in dendritic cells
-
Ohtani M, Nagai S, Kondo S, Mizuno S, Nakamura K, Tanabe M, Takeuchi T, Matsuda S, Koyasu S (2008). Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharideinduced interleukin-12 production in dendritic cells. Blood 112, 635-643.
-
(2008)
Blood
, vol.112
, pp. 635-643
-
-
Ohtani, M.1
Nagai, S.2
Kondo, S.3
Mizuno, S.4
Nakamura, K.5
Tanabe, M.6
Takeuchi, T.7
Matsuda, S.8
Koyasu, S.9
-
41
-
-
0034507903
-
BCAP: The tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation
-
Okada T, Maeda A, Iwamatsu A, Gotoh K, Kurosaki T (2000). BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation. Immunity 13, 817-827.
-
(2000)
Immunity
, vol.13
, pp. 817-827
-
-
Okada, T.1
Maeda, A.2
Iwamatsu, A.3
Gotoh, K.4
Kurosaki, T.5
-
42
-
-
67349182481
-
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
-
Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO (2009). The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 458, 1191-1195.
-
(2009)
Nature
, vol.458
, pp. 1191-1195
-
-
Park, B.S.1
Song, D.H.2
Kim, H.M.3
Choi, B.S.4
Lee, H.5
Lee, J.O.6
-
43
-
-
77955406845
-
Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production
-
Peirce MJ, Brook M, Morrice N, Snelgrove R, Begum S, Lanfrancotti A, Notley C, Hussell T, Cope AP, Wait R (2010). Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production. PLoS One 3, e11465.
-
(2010)
PLoS One
, vol.3
, pp. e11465
-
-
Peirce, M.J.1
Brook, M.2
Morrice, N.3
Snelgrove, R.4
Begum, S.5
Lanfrancotti, A.6
Notley, C.7
Hussell, T.8
Cope, A.P.9
Wait, R.10
-
44
-
-
84922101673
-
Co-operation of TLR4 and raft proteins in LPS-induced proinflammatory signaling
-
Plociennikowska A, Hromada-Judycka A, Borzeçka K, Kwiatkowska K (2015a). Co-operation of TLR4 and raft proteins in LPS-induced proinflammatory signaling. Cell Mol Life Sci 72, 557-581.
-
(2015)
Cell Mol Life Sci
, vol.72
, pp. 557-581
-
-
Plociennikowska, A.1
Hromada-Judycka, A.2
Borzeçka, K.3
Kwiatkowska, K.4
-
45
-
-
84949844935
-
LPS-induced clustering of CD14 triggers generation of PI(4,5) P2
-
Plociennikowska A, Zdioruk MI, Traczyk G, Swiatkowska A, Kwiatkowska K (2015b). LPS-induced clustering of CD14 triggers generation of PI(4, 5) P2. J Cell Sci 128, 4096-4111.
-
(2015)
J Cell Sci
, vol.128
, pp. 4096-4111
-
-
Plociennikowska, A.1
Zdioruk, M.I.2
Traczyk, G.3
Swiatkowska, A.4
Kwiatkowska, K.5
-
46
-
-
79960907910
-
The MAPK cascades: Signaling components, nuclear roles and mechanisms of nuclear translocation
-
Plotnikov A, Zehorai E, Procaccia S, Seger R (2011). The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation. Biochim Biophys Acta 1813, 1619-1633.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1619-1633
-
-
Plotnikov, A.1
Zehorai, E.2
Procaccia, S.3
Seger, R.4
-
47
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, et al. (1998). Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
-
48
-
-
38349051325
-
A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration
-
Posevitz-Fejfar A, Smida M, Kliche S, Hartig R, Schraven B, Lindquist JA (2008). A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration. Eur J Immunol 38, 250-259.
-
(2008)
Eur J Immunol
, vol.38
, pp. 250-259
-
-
Posevitz-Fejfar, A.1
Smida, M.2
Kliche, S.3
Hartig, R.4
Schraven, B.5
Lindquist, J.A.6
-
49
-
-
83255170447
-
S100A6 mediates nuclear translocation of Sgt1: A heat shock-regulated protein
-
Prus W, Filipek A (2010). S100A6 mediates nuclear translocation of Sgt1: a heat shock-regulated protein. Amino Acids 41, 781-787.
-
(2010)
Amino Acids
, vol.41
, pp. 781-787
-
-
Prus, W.1
Filipek, A.2
-
50
-
-
0035041672
-
Cross-correlation analysis of inner-leaflet- anchored green fluorescent protein co-redistributed with IgE receptors and outer leaflet lipid raft components
-
Pyenta PS, Holowka D, Baird B (2001). Cross-correlation analysis of inner-leaflet- anchored green fluorescent protein co-redistributed with IgE receptors and outer leaflet lipid raft components. Biophys J 80, 2120-2132.
-
(2001)
Biophys J
, vol.80
, pp. 2120-2132
-
-
Pyenta, P.S.1
Holowka, D.2
Baird, B.3
-
51
-
-
84959317195
-
Assessment of clinical criteria for sepsis: For the third international consensus definitions for sepsis and septic shock (Sepsis-3)
-
Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, Rubenfeld G, Kahn JM, Shankar-Hari M, Singer M, et al. (2016). Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3). J Am Med Assoc 315, 762-774.
-
(2016)
J Am Med Assoc
, vol.315
, pp. 762-774
-
-
Seymour, C.W.1
Liu, V.X.2
Iwashyna, T.J.3
Brunkhorst, F.M.4
Rea, T.D.5
Scherag, A.6
Rubenfeld, G.7
Kahn, J.M.8
Shankar-Hari, M.9
Singer, M.10
-
52
-
-
34547932452
-
Src kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets
-
Shvartsman DE, Donaldson JC, Diaz B, Gutman O, Martin GS, Henis YI (2007). Src kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets. J Cell Biol 178, 675-686.
-
(2007)
J Cell Biol
, vol.178
, pp. 675-686
-
-
Shvartsman, D.E.1
Donaldson, J.C.2
Diaz, B.3
Gutman, O.4
Martin, G.S.5
Henis, Y.I.6
-
53
-
-
35548985405
-
Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages
-
Smolinska MJ, Horwood NJ, Page TH, Smallie T, Foxwell BM (2008). Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages. Mol Immunol 45, 990-1000.
-
(2008)
Mol Immunol
, vol.45
, pp. 990-1000
-
-
Smolinska, M.J.1
Horwood, N.J.2
Page, T.H.3
Smallie, T.4
Foxwell, B.M.5
-
54
-
-
82755187669
-
Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP- 1
-
Smolinska MJ, Page TH, Urbaniak AM, Mutch BE, Horwood NJ (2011). Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP- 1. J Immunol 187, 6043-6051.
-
(2011)
J Immunol
, vol.187
, pp. 6043-6051
-
-
Smolinska, M.J.1
Page, T.H.2
Urbaniak, A.M.3
Mutch, B.E.4
Horwood, N.J.5
-
55
-
-
0027434028
-
Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56lyn
-
Stefanova I, Corcoran ML, Horak EM, Wahl LM, Bolen JB, Horak ID (1993). Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56lyn. J Biol Chem 268, 20725-20728.
-
(1993)
J Biol Chem
, vol.268
, pp. 20725-20728
-
-
Stefanova, I.1
Corcoran, M.L.2
Horak, E.M.3
Wahl, L.M.4
Bolen, J.B.5
Horak, I.D.6
-
56
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, et al. (2010). CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat Immunol 11, 155-161.
-
(2010)
Nat Immunol
, vol.11
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
Van Gils, J.M.4
Deng, J.5
Halle, A.6
Rayner, K.J.7
Boyer, L.8
Zhong, R.9
Frazier, W.A.10
-
57
-
-
34249066421
-
GPI-anchored receptor clusters transiently recruit Lyn and Gα for temporary cluster immobilization and Lyn activation: Single-molecule tracking study 1
-
Suzuki KG, Fujiwara TK, Sanematsu F, Iino R, Edidin M, Kusumi A (2007). GPI-anchored receptor clusters transiently recruit Lyn and Gα for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1. J Cell Biol 177, 717-730.
-
(2007)
J Cell Biol
, vol.177
, pp. 717-730
-
-
Suzuki, K.G.1
Fujiwara, T.K.2
Sanematsu, F.3
Iino, R.4
Edidin, M.5
Kusumi, A.6
-
58
-
-
41349111083
-
Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts
-
Tauzin S, Ding H, Khatib K, Ahmad I, Burdevet D, van Echten-Deckert G, Lindquist JA, Schraven B, Din NU, Borisch B, Hoessli DC (2008). Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts. Blood 111, 2310-2320.
-
(2008)
Blood
, vol.111
, pp. 2310-2320
-
-
Tauzin, S.1
Ding, H.2
Khatib, K.3
Ahmad, I.4
Burdevet, D.5
Van Echten-Deckert, G.6
Lindquist, J.A.7
Schraven, B.8
Din, N.U.9
Borisch, B.10
Hoessli, D.C.11
-
59
-
-
84867277240
-
Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K
-
Troutman TD, Bazan JF, Pasare C (2012a). Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K. Cell Cycle 11, 3559-67.
-
(2012)
Cell Cycle
, vol.11
, pp. 3559-3567
-
-
Troutman, T.D.1
Bazan, J.F.2
Pasare, C.3
-
60
-
-
84856008042
-
Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt
-
Troutman TD, Hu W, Fulenchek S, Yamazaki T, Kurosaki T, Bazan JF, Pasare C (2012b). Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt. Proc Natl Acad Sci USA 109, 273-278.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 273-278
-
-
Troutman, T.D.1
Hu, W.2
Fulenchek, S.3
Yamazaki, T.4
Kurosaki, T.5
Bazan, J.F.6
Pasare, C.7
-
61
-
-
0034614557
-
Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids
-
Webb Y, Hermida-Matsumoto L, Resh MD (2000). Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids. J Biol Chem 275, 261-270.
-
(2000)
J Biol Chem
, vol.275
, pp. 261-270
-
-
Webb, Y.1
Hermida-Matsumoto, L.2
Resh, M.D.3
-
62
-
-
27744592100
-
Positive and negative regulation of mast cell activation by Lyn via the FcaRI
-
Xiao W, Nishimoto H, Hong H, Kitaura J, Nunomura S, Maeda- Yamamoto M, Kawakami Y, Lowell CA, Ra C, Kawakami T (2005). Positive and negative regulation of mast cell activation by Lyn via the Fc-RI. J Immunol 175, 6885-6892.
-
(2005)
J Immunol
, vol.175
, pp. 6885-6892
-
-
Xiao, W.1
Nishimoto, H.2
Hong, H.3
Kitaura, J.4
Nunomura, S.5
Maeda-Yamamoto, M.6
Kawakami, Y.7
Lowell, C.A.8
Ra, C.9
Kawakami, T.10
-
63
-
-
12444331082
-
Lyn tyrosine kinase: Accentuating the positive and the negative
-
Xu Y, Harder KW, Huntington ND, Hibbs ML, Tarlinton DM (2005). Lyn tyrosine kinase: accentuating the positive and the negative. Immunity 22, 9-18.
-
(2005)
Immunity
, vol.22
, pp. 9-18
-
-
Xu, Y.1
Harder, K.W.2
Huntington, N.D.3
Hibbs, M.L.4
Tarlinton, D.M.5
-
64
-
-
84867742499
-
Phosphatidylinositol-3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase
-
Xu Y, Huntington ND, Harder KW, Nandurkar H, Hibbs ML, Tarlinton DM (2012). Phosphatidylinositol-3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase. Immunol Cell Biol 90, 903-911.
-
(2012)
Immunol Cell Biol
, vol.90
, pp. 903-911
-
-
Xu, Y.1
Huntington, N.D.2
Harder, K.W.3
Nandurkar, H.4
Hibbs, M.L.5
Tarlinton, D.M.6
-
65
-
-
0033520997
-
Functional interaction between SHPTP1 and the Lyn tyrosine kinase in the apoptotic response to DNA damage
-
Yoshida K, Kharbanda S, Kufe D (1999). Functional interaction between SHPTP1 and the Lyn tyrosine kinase in the apoptotic response to DNA damage. J Biol Chem 274, 34663-34668.
-
(1999)
J Biol Chem
, vol.274
, pp. 34663-34668
-
-
Yoshida, K.1
Kharbanda, S.2
Kufe, D.3
-
66
-
-
81055129630
-
CD14 controls the LPS-induced endocytosis of Toll-like receptor 4
-
Zanoni I, Ostuni R, Marek LR, Barresi S, Barbalat R, Barton GM, Granucci F, Kagan JC (2011). CD14 controls the LPS-induced endocytosis of Toll-like receptor 4. Cell 147, 868-880.
-
(2011)
Cell
, vol.147
, pp. 868-880
-
-
Zanoni, I.1
Ostuni, R.2
Marek, L.R.3
Barresi, S.4
Barbalat, R.5
Barton, G.M.6
Granucci, F.7
Kagan, J.C.8
-
67
-
-
77952695712
-
Tandem fluorescence imaging of dynamic S-acylation and protein turnover
-
Zhang MM, Tsou LK, Charron G, Raghavan AS, Hang HC (2010). Tandem fluorescence imaging of dynamic S-acylation and protein turnover. Proc Natl Acad Sci USA 107, 8627-8632.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8627-8632
-
-
Zhang, M.M.1
Tsou, L.K.2
Charron, G.3
Raghavan, A.S.4
Hang, H.C.5
|